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Items: 1 to 50 of 67

1.

CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin.

Roser-Page S, Vikulina T, Weiss D, Habib MM, Beck GR Jr, Pacifici R, Lane TF, Weitzmann MN.

Ann N Y Acad Sci. 2018 Mar;1415(1):21-33. doi: 10.1111/nyas.13643. Epub 2018 Mar 3.

2.

NOTCH1 is a mechanosensor in adult arteries.

Mack JJ, Mosqueiro TS, Archer BJ, Jones WM, Sunshine H, Faas GC, Briot A, Aragón RL, Su T, Romay MC, McDonald AI, Kuo CH, Lizama CO, Lane TF, Zovein AC, Fang Y, Tarling EJ, de Aguiar Vallim TQ, Navab M, Fogelman AM, Bouchard LS, Iruela-Arispe ML.

Nat Commun. 2017 Nov 20;8(1):1620. doi: 10.1038/s41467-017-01741-8.

3.

Ras Signaling Is a Key Determinant for Metastatic Dissemination and Poor Survival of Luminal Breast Cancer Patients.

Wright KL, Adams JR, Liu JC, Loch AJ, Wong RG, Jo CE, Beck LA, Santhanam DR, Weiss L, Mei X, Lane TF, Koralov SB, Done SJ, Woodgett JR, Zacksenhaus E, Hu P, Egan SE.

Cancer Res. 2015 Nov 15;75(22):4960-72. doi: 10.1158/0008-5472.CAN-14-2992. Epub 2015 Sep 23.

4.

IRE1 phosphatase PP2Ce regulates adaptive ER stress response in the postpartum mammary gland.

Ren S, Lu G, Ota A, Zhou ZH, Vondriska TM, Lane TF, Wang Y.

PLoS One. 2014 Nov 4;9(11):e111606. doi: 10.1371/journal.pone.0111606. eCollection 2014.

5.

Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling.

Kim WS, Zhu Y, Deng Q, Chin CJ, He CB, Grieco AJ, Dravid GG, Parekh C, Hollis RP, Lane TF, Bouhassira EE, Kohn DB, Crooks GM.

Stem Cells. 2014 Jun;32(6):1503-14. doi: 10.1002/stem.1677.

6.

PIAS1 regulates breast tumorigenesis through selective epigenetic gene silencing.

Liu B, Tahk S, Yee KM, Yang R, Yang Y, Mackie R, Hsu C, Chernishof V, O'Brien N, Jin Y, Fan G, Lane TF, Rao J, Slamon D, Shuai K.

PLoS One. 2014 Feb 24;9(2):e89464. doi: 10.1371/journal.pone.0089464. eCollection 2014.

7.

PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response.

Lu G, Ota A, Ren S, Franklin S, Rau CD, Ping P, Lane TF, Zhou ZH, Reue K, Lusis AJ, Vondriska T, Wang Y.

Mol Metab. 2013 Aug 3;2(4):405-16. doi: 10.1016/j.molmet.2013.07.005. eCollection 2013.

8.

Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B.

Li JY, Adams J, Calvi LM, Lane TF, Weitzmann MN, Pacifici R.

Blood. 2013 Oct 3;122(14):2346-57. doi: 10.1182/blood-2013-03-487801. Epub 2013 Aug 16.

9.

Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance.

Roodhart JM, He H, Daenen LG, Monvoisin A, Barber CL, van Amersfoort M, Hofmann JJ, Radtke F, Lane TF, Voest EE, Iruela-Arispe ML.

Blood. 2013 Jul 4;122(1):143-53. doi: 10.1182/blood-2012-11-459347. Epub 2013 May 20.

10.

PTH expands short-term murine hemopoietic stem cells through T cells.

Li JY, Adams J, Calvi LM, Lane TF, DiPaolo R, Weitzmann MN, Pacifici R.

Blood. 2012 Nov 22;120(22):4352-62. doi: 10.1182/blood-2012-06-438531. Epub 2012 Sep 5.

11.

Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.

Adams JR, Xu K, Liu JC, Agamez NM, Loch AJ, Wong RG, Wang W, Wright KL, Lane TF, Zacksenhaus E, Egan SE.

Cancer Res. 2011 Apr 1;71(7):2706-17. doi: 10.1158/0008-5472.CAN-10-0738. Epub 2011 Feb 15.

12.

Disruption of reelin signaling alters mammary gland morphogenesis.

Khialeeva E, Lane TF, Carpenter EM.

Development. 2011 Feb;138(4):767-76. doi: 10.1242/dev.057588.

13.

BRCA1 Forms a Functional Complex with γ-H2AX as a Late Response to Genotoxic Stress.

Krum SA, la Rosa Dalugdugan Ed, Miranda-Carboni GA, Lane TF.

J Nucleic Acids. 2010 Sep 27;2010. pii: 801594. doi: 10.4061/2010/801594.

14.

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.

Jiang Z, Deng T, Jones R, Li H, Herschkowitz JI, Liu JC, Weigman VJ, Tsao MS, Lane TF, Perou CM, Zacksenhaus E.

J Clin Invest. 2010 Sep;120(9):3296-309. doi: 10.1172/JCI41490. Epub 2010 Aug 2.

15.

Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells.

Stevens JR, Miranda-Carboni GA, Singer MA, Brugger SM, Lyons KM, Lane TF.

J Bone Miner Res. 2010 Oct;25(10):2138-47. doi: 10.1002/jbmr.118.

16.

Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism.

Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML.

Dev Cell. 2010 Jan 19;18(1):39-51. doi: 10.1016/j.devcel.2009.12.006.

17.

University of California Research Seminar Network: a prospectus.

Carey JR, Christian Laursen J, Glaser SD, Raphael S, Miller GH, Crawford J, Lane TF, Liwang PJ, Hammond K, Groves T, Pittet JF, Stuart D, Kolaitis PG, Serwer L, Chen M, Feer K.

PLoS Biol. 2010 Jan 19;8(1):e1000289. doi: 10.1371/journal.pbio.1000289. No abstract available.

18.

T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling.

Terauchi M, Li JY, Bedi B, Baek KH, Tawfeek H, Galley S, Gilbert L, Nanes MS, Zayzafoon M, Guldberg R, Lamar DL, Singer MA, Lane TF, Kronenberg HM, Weitzmann MN, Pacifici R.

Cell Metab. 2009 Sep;10(3):229-40. doi: 10.1016/j.cmet.2009.07.010.

19.

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors.

Liu Q, Nguyen DH, Dong Q, Shitaku P, Chung K, Liu OY, Tso JL, Liu JY, Konkankit V, Cloughesy TF, Mischel PS, Lane TF, Liau LM, Nelson SF, Tso CL.

J Neurooncol. 2009 Aug;94(1):1-19. doi: 10.1007/s11060-009-9919-z. Epub 2009 May 26.

20.

A versatile targeting system with lentiviral vectors bearing the biotin-adaptor peptide.

Morizono K, Xie Y, Helguera G, Daniels TR, Lane TF, Penichet ML, Chen IS.

J Gene Med. 2009 Aug;11(8):655-63. doi: 10.1002/jgm.1345.

21.

Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation.

Moraes RC, Chang H, Harrington N, Landua JD, Prigge JT, Lane TF, Wainwright BJ, Hamel PA, Lewis MT.

Development. 2009 May;136(9):1423-32. doi: 10.1242/dev.023994. Epub 2009 Mar 18.

22.

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.

Miranda-Carboni GA, Krum SA, Yee K, Nava M, Deng QE, Pervin S, Collado-Hidalgo A, Galic Z, Zack JA, Nakayama K, Nakayama KI, Lane TF.

Genes Dev. 2008 Nov 15;22(22):3121-34. doi: 10.1101/gad.1692808.

23.

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.

Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M.

EMBO J. 2008 Feb 6;27(3):535-45. doi: 10.1038/sj.emboj.7601984. Epub 2008 Jan 24.

24.

Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation.

Bennett CN, Ouyang H, Ma YL, Zeng Q, Gerin I, Sousa KM, Lane TF, Krishnan V, Hankenson KD, MacDougald OA.

J Bone Miner Res. 2007 Dec;22(12):1924-32.

25.

Wnt signaling interacts with Shh to regulate taste papilla development.

Iwatsuki K, Liu HX, Grónder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2253-8. Epub 2007 Feb 6.

26.

VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium.

Monvoisin A, Alva JA, Hofmann JJ, Zovein AC, Lane TF, Iruela-Arispe ML.

Dev Dyn. 2006 Dec;235(12):3413-22.

27.

BRCA1 associates with the inactive X chromosome in late S-phase, coupled with transient H2AX phosphorylation.

Chadwick BP, Lane TF.

Chromosoma. 2005 Dec;114(6):432-9. Epub 2005 Nov 15.

PMID:
16240122
28.

COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice.

Narko K, Zweifel B, Trifan O, Ristimäki A, Lane TF, Hla T.

Prostaglandins Other Lipid Mediat. 2005 May;76(1-4):86-94.

PMID:
15967164
29.

The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia.

Chang SH, Ai Y, Breyer RM, Lane TF, Hla T.

Cancer Res. 2005 Jun 1;65(11):4496-9.

30.

Regulation of osteoblastogenesis and bone mass by Wnt10b.

Bennett CN, Longo KA, Wright WS, Suva LJ, Lane TF, Hankenson KD, MacDougald OA.

Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3324-9. Epub 2005 Feb 22.

31.

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts.

Vertino AM, Taylor-Jones JM, Longo KA, Bearden ED, Lane TF, McGehee RE Jr, MacDougald OA, Peterson CA.

Mol Biol Cell. 2005 Apr;16(4):2039-48. Epub 2005 Jan 26.

32.

Type I interferon production enhances susceptibility to Listeria monocytogenes infection.

O'Connell RM, Saha SK, Vaidya SA, Bruhn KW, Miranda GA, Zarnegar B, Perry AK, Nguyen BO, Lane TF, Taniguchi T, Miller JF, Cheng G.

J Exp Med. 2004 Aug 16;200(4):437-45. Epub 2004 Aug 9.

33.

BRCA1 and transcription.

Lane TF.

Cancer Biol Ther. 2004 Jun;3(6):528-33. Epub 2004 Jun 24. Review.

PMID:
15254397
34.

Toll-like receptors induce a phagocytic gene program through p38.

Doyle SE, O'Connell RM, Miranda GA, Vaidya SA, Chow EK, Liu PT, Suzuki S, Suzuki N, Modlin RL, Yeh WC, Lane TF, Cheng G.

J Exp Med. 2004 Jan 5;199(1):81-90. Epub 2003 Dec 29.

35.

Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression.

Chang SH, Liu CH, Conway R, Han DK, Nithipatikom K, Trifan OC, Lane TF, Hla T.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):591-6. Epub 2003 Dec 19.

36.

BRCA1 associates with processive RNA polymerase II.

Krum SA, Miranda GA, Lin C, Lane TF.

J Biol Chem. 2003 Dec 26;278(52):52012-20. Epub 2003 Sep 23.

37.
38.
39.

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland.

Li G, Robinson GW, Lesche R, Martinez-Diaz H, Jiang Z, Rozengurt N, Wagner KU, Wu DC, Lane TF, Liu X, Hennighausen L, Wu H.

Development. 2002 Sep;129(17):4159-70.

40.

Identification of a novel endothelial-derived gene EG-1.

Liu C, Zhang L, Shao ZM, Beatty P, Sartippour M, Lane TF, Barsky SH, Livingston E, Nguyen M.

Biochem Biophys Res Commun. 2002 Jan 11;290(1):602-12.

PMID:
11779215
41.

Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor.

Rodriguez-Manzaneque JC, Lane TF, Ortega MA, Hynes RO, Lawler J, Iruela-Arispe ML.

Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12485-90. Epub 2001 Oct 16.

42.

Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice.

Liu CH, Chang SH, Narko K, Trifan OC, Wu MT, Smith E, Haudenschild C, Lane TF, Hla T.

J Biol Chem. 2001 May 25;276(21):18563-9. Epub 2001 Mar 7.

43.

Gene replacement with the human BRCA1 locus: tissue specific expression and rescue of embryonic lethality in mice.

Lane TF, Lin C, Brown MA, Solomon E, Leder P.

Oncogene. 2000 Aug 24;19(36):4085-90.

44.

Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution.

Pepper MS, Baetens D, Mandriota SJ, Di Sanza C, Oikemus S, Lane TF, Soriano JV, Montesano R, Iruela-Arispe ML.

Dev Dyn. 2000 Jul;218(3):507-24.

45.

METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.

Vázquez F, Hastings G, Ortega MA, Lane TF, Oikemus S, Lombardo M, Iruela-Arispe ML.

J Biol Chem. 1999 Aug 13;274(33):23349-57.

46.
47.

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice.

Lane TF, Deng C, Elson A, Lyu MS, Kozak CA, Leder P.

Genes Dev. 1995 Nov 1;9(21):2712-22. Erratum in: Genes Dev 1996 Feb 1;10(3):365.

48.

Distribution of SPARC in normal and neoplastic human tissue.

Porter PL, Sage EH, Lane TF, Funk SE, Gown AM.

J Histochem Cytochem. 1995 Aug;43(8):791-800.

PMID:
7622842
49.
50.

Expression of SPARC during development of the chicken chorioallantoic membrane: evidence for regulated proteolysis in vivo.

Iruela-Arispe ML, Lane TF, Redmond D, Reilly M, Bolender RP, Kavanagh TJ, Sage EH.

Mol Biol Cell. 1995 Mar;6(3):327-43.

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