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Prostate cancer survivors' preferences on the delivery of diet and lifestyle advice: a pilot best-worst discrete choice experiment.

Robles LA, Wright SJ, Hackshaw-McGeagh L, Shingler E, Shiridzinomwa C, Lane JA, Martin RM, Burden S.

Pilot Feasibility Stud. 2020 Jan 6;6:2. doi: 10.1186/s40814-019-0549-8. eCollection 2020.


The ProtecT trial: analysis of the patient cohort, baseline risk stratification and disease progression.

Bryant RJ, Oxley J, Young GJ, Lane JA, Metcalfe C, Davis M, Turner EL, Martin RM, Goepel JR, Varma M, Griffiths DF, Grigor K, Mayer N, Warren AY, Bhattarai S, Dormer J, Mason M, Staffurth J, Walsh E, Rosario DJ, Catto JWF, Neal DE, Donovan JL, Hamdy FC; ProtecT Study Group.

BJU Int. 2020 Jan 3. doi: 10.1111/bju.14987. [Epub ahead of print]


Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatment Received.

Neal DE, Metcalfe C, Donovan JL, Lane JA, Davis M, Young GJ, Dutton SJ, Walsh EI, Martin RM, Peters TJ, Turner EL, Mason M, Bollina P, Catto J, Doherty A, Gillatt D, Gnanapragasam V, Holding P, Hughes O, Kockelbergh R, Kynaston H, Oxley J, Paul A, Paez E, Rosario DJ, Rowe E, Staffurth J, Altman DG, Hamdy FC; ProtecT Study Group.

Eur Urol. 2020 Mar;77(3):320-330. doi: 10.1016/j.eururo.2019.10.030. Epub 2019 Nov 24.


Best emollients for eczema (BEE) - comparing four types of emollients in children with eczema: protocol for randomised trial and nested qualitative study.

Ridd MJ, Wells S, Edwards L, Santer M, MacNeill S, Sanderson E, Sutton E, Shaw ARG, Banks J, Garfield K, Roberts A, Barrett TJ, Baxter H, Taylor J, Lane JA, Hay AD, Williams HC, Thomas KS.

BMJ Open. 2019 Nov 6;9(11):e033387. doi: 10.1136/bmjopen-2019-033387.


Phase II randomised control feasibility trial of a nutrition and physical activity intervention after radical prostatectomy for prostate cancer.

Hackshaw-McGeagh LE, Penfold C, Shingler E, Robles LA, Perks CM, Holly JMP, Rowe E, Koupparis A, Bahl A, Persad R, Shiridzinomwa C, Johnson L, Biernacka KM, Frankow A, Woodside JV, Gilchrist S, Oxley J, Abrams P, Lane JA, Martin RM.

BMJ Open. 2019 Nov 6;9(11):e029480. doi: 10.1136/bmjopen-2019-029480.


Clinical features, biochemistry and HLA-DRB1 status in children and adolescents with diabetes in Dhaka, Bangladesh.

Zabeen B, Govender D, Hassan Z, Noble JA, Lane JA, Mack SJ, Atkinson MA, Azad K, Wasserfall CH, Ogle GD.

Diabetes Res Clin Pract. 2019 Dec;158:107894. doi: 10.1016/j.diabres.2019.107894. Epub 2019 Oct 24.


A third trial oversight committee: Functions, benefits and issues.

Lane JA, Gamble C, Cragg WJ, Tembo D, Sydes MR.

Clin Trials. 2020 Feb;17(1):106-112. doi: 10.1177/1740774519881619. Epub 2019 Oct 30.


TReatIng Urinary symptoms in Men in Primary Healthcare using non-pharmacological and non-surgical interventions (TRIUMPH) compared with usual care: study protocol for a cluster randomised controlled trial.

Frost J, Lane JA, Cotterill N, Fader M, Hackshaw-McGeagh L, Hashim H, Macaulay M, MacNeill SJ, Noble S, Rees J, Ridd MJ, Robles L, Taylor G, Taylor J, Drake MJ, Worthington J.

Trials. 2019 Sep 2;20(1):546. doi: 10.1186/s13063-019-3648-1.


Precision Nutrition and the Microbiome Part II: Potential Opportunities and Pathways to Commercialisation.

Mills S, Lane JA, Smith GJ, Grimaldi KA, Ross RP, Stanton C.

Nutrients. 2019 Jun 27;11(7). pii: E1468. doi: 10.3390/nu11071468. Review.


Factors associated with trial recruitment, preferences, and treatments received were elucidated in a comprehensive cohort study.

Donovan JL, Opmeer B, Young GJ, Mills N, Martin RM, Lane JA, Metcalfe C, Peters TJ, Davis M, Turner EL, Walsh E, Neal DE, Hamdy FC; ProtecT Study Group.

J Clin Epidemiol. 2019 Sep;113:200-213. doi: 10.1016/j.jclinepi.2019.05.036. Epub 2019 Jun 3.


Challenges to and Facilitators of Recruitment to an Alzheimer's Disease Clinical Trial: A Qualitative Interview Study.

Clement C, Selman LE, Kehoe PG, Howden B, Lane JA, Horwood J.

J Alzheimers Dis. 2019;69(4):1067-1075. doi: 10.3233/JAD-190146.


Clinical and Patient-reported Outcome Measures in Men Referred for Consideration of Surgery to Treat Lower Urinary Tract Symptoms: Baseline Results and Diagnostic Findings of the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM).

Lewis AL, Young GJ, Abrams P, Blair PS, Chapple C, Glazener CMA, Horwood J, McGrath JS, Noble S, Taylor GT, Ito H, Belal M, Davies MC, Dickinson AJ, Foley CL, Foley S, Fulford S, Gammal MM, Garthwaite M, Harris MRE, Ilie PC, Jones R, Sabbagh S, Mason RG, McLarty E, Mishra V, Mom J, Morley R, Natale S, Nitkunan T, Page T, Payne D, Rashid TG, Saeb-Parsy K, Sandhu SS, Simoes A, Singh G, Sullivan M, Tempest HV, Viswanath S, Walker RMH, Lane JA, Drake MJ.

Eur Urol Focus. 2019 May;5(3):340-350. doi: 10.1016/j.euf.2019.04.006. Epub 2019 Apr 30.


Precision Nutrition and the Microbiome, Part I: Current State of the Science.

Mills S, Stanton C, Lane JA, Smith GJ, Ross RP.

Nutrients. 2019 Apr 24;11(4). pii: E923. doi: 10.3390/nu11040923. Review.


The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF-I, IGF-II, IGFBP-1, IGFBP-2 and IGFBP-3 in a pooled analysis of 16,024 men from 22 studies.

Watts EL, Perez-Cornago A, Appleby PN, Albanes D, Ardanaz E, Black A, Bueno-de-Mesquita HB, Chan JM, Chen C, Chubb SAP, Cook MB, Deschasaux M, Donovan JL, English DR, Flicker L, Freedman ND, Galan P, Giles GG, Giovannucci EL, Gunter MJ, Habel LA, Häggström C, Haiman C, Hamdy FC, Hercberg S, Holly JM, Huang J, Huang WY, Johansson M, Kaaks R, Kubo T, Lane JA, Layne TM, Le Marchand L, Martin RM, Metter EJ, Mikami K, Milne RL, Morris HA, Mucci LA, Neal DE, Neuhouser ML, Oliver SE, Overvad K, Ozasa K, Pala V, Pernar CH, Pollak M, Rowlands MA, Schaefer CA, Schenk JM, Stattin P, Tamakoshi A, Thysell E, Touvier M, Trichopoulou A, Tsilidis KK, Van Den Eeden SK, Weinstein SJ, Wilkens L, Yeap BB, Key TJ, Allen NE, Travis RC.

Int J Cancer. 2019 Dec 15;145(12):3244-3256. doi: 10.1002/ijc.32276. Epub 2019 Apr 4.


Clinical features, biochemistry and HLA-DRB1 status in youth-onset type 1 diabetes in Pakistan.

Fawwad A, Govender D, Ahmedani MY, Basit A, Lane JA, Mack SJ, Atkinson MA, Henry Wasserfall C, Ogle GD, Noble JA.

Diabetes Res Clin Pract. 2019 Mar;149:9-17. doi: 10.1016/j.diabres.2019.01.023. Epub 2019 Jan 30.


Bovine colostrum-driven modulation of intestinal epithelial cells for increased commensal colonisation.

Morrin ST, Lane JA, Marotta M, Bode L, Carrington SD, Irwin JA, Hickey RM.

Appl Microbiol Biotechnol. 2019 Mar;103(6):2745-2758. doi: 10.1007/s00253-019-09642-0. Epub 2019 Jan 26.


Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study.

Adams CD, Richmond R, Ferreira DLS, Spiller W, Tan V, Zheng J, Würtz P, Donovan J, Hamdy F, Neal D, Lane JA, Smith GD, Relton C, Eeles RA, Haiman CA, Kote-Jarai Z, Schumacher FR, Olama AAA, Benlloch S, Muir K, Berndt SI, Conti DV, Wiklund F, Chanock SJ, Gapstur S, Stevens VL, Tangen CM, Batra J, Clements JA, Gronberg H, Pashayan N, Schleutker J, Albanes D, Wolk A, West CML, Mucci LA, Cancel-Tassin G, Koutros S, Sorensen KD, Maehle L, Travis RC, Hamilton RJ, Ingles SA, Rosenstein BS, Lu YJ, Giles GG, Kibel AS, Vega A, Kogevinas M, Penney KL, Park JY, Stanford JL, Cybulski C, Nordestgaard BG, Brenner H, Maier C, Kim J, John EM, Teixeira MR, Neuhausen SL, De Ruyck K, Razack A, Newcomb LF, Lessel D, Kaneva RP, Usmani N, Claessens F, Townsend PA, Dominguez MG, Roobol MJ, Menegaux F, Khaw KT, Cannon-Albright LA, Pandha H, Thibodeau SN, Martin RM; PRACTICAL consortium.

Cancer Epidemiol Biomarkers Prev. 2019 Jan;28(1):208-216. doi: 10.1158/1055-9965.EPI-18-0079. Epub 2018 Oct 23.


ProDiet: A Phase II Randomized Placebo-controlled Trial of Green Tea Catechins and Lycopene in Men at Increased Risk of Prostate Cancer.

Lane JA, Er V, Avery KNL, Horwood J, Cantwell M, Caro GP, Crozier A, Smith GD, Donovan JL, Down L, Hamdy FC, Gillatt D, Holly J, Macefield R, Moody H, Neal DE, Walsh E, Martin RM, Metcalfe C.

Cancer Prev Res (Phila). 2018 Nov;11(11):687-696. doi: 10.1158/1940-6207.CAPR-18-0147. Epub 2018 Oct 11.


Epidemiology of childhood-onset type 1 diabetes in Azerbaijan: Incidence, clinical features, biochemistry, and HLA-DRB1 status.

Ahmadov GA, Govender D, Atkinson MA, Sultanova RA, Eubova AA, Wasserfall CH, Mack SJ, Lane JA, Noble JA, Ogle GD.

Diabetes Res Clin Pract. 2018 Oct;144:252-259. doi: 10.1016/j.diabres.2018.09.009. Epub 2018 Sep 13.


Systematic review evaluating randomized controlled trials of smoking and alcohol cessation interventions in people with head and neck cancer and oral dysplasia.

Shingler E, Robles LA, Perry R, Penfold C, Ness AR, Thomas S, Lane JA, Martin RM.

Head Neck. 2018 Aug;40(8):1845-1853. doi: 10.1002/hed.25138. Epub 2018 Mar 30.


Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial.

Martin RM, Donovan JL, Turner EL, Metcalfe C, Young GJ, Walsh EI, Lane JA, Noble S, Oliver SE, Evans S, Sterne JAC, Holding P, Ben-Shlomo Y, Brindle P, Williams NJ, Hill EM, Ng SY, Toole J, Tazewell MK, Hughes LJ, Davies CF, Thorn JC, Down E, Davey Smith G, Neal DE, Hamdy FC; CAP Trial Group.

JAMA. 2018 Mar 6;319(9):883-895. doi: 10.1001/jama.2018.0154.


Developing new age-specific prostate-specific antigen thresholds for testing for prostate cancer.

Gilbert R, Tilling K, Martin RM, Lane JA, Davis M, Hamdy FC, Neal DE, Donovan JL, Metcalfe C.

Cancer Causes Control. 2018 Mar;29(3):383-388. doi: 10.1007/s10552-018-1014-3. Epub 2018 Feb 16.


'Recruitment, recruitment, recruitment' - the need for more focus on retention: a qualitative study of five trials.

Daykin A, Clement C, Gamble C, Kearney A, Blazeby J, Clarke M, Lane JA, Shaw A.

Trials. 2018 Jan 29;19(1):76. doi: 10.1186/s13063-018-2467-0.


A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial.

Donovan JL, Young GJ, Walsh EI, Metcalfe C, Lane JA, Martin RM, Tazewell MK, Davis M, Peters TJ, Turner EL, Mills N, Khazragui H, Khera TK, Neal DE, Hamdy FC; ProtecT Study Group.

J Clin Epidemiol. 2018 Apr;96:35-46. doi: 10.1016/j.jclinepi.2017.12.019. Epub 2017 Dec 27.


'We all want to succeed, but we've also got to be realistic about what is happening': an ethnographic study of relationships in trial oversight and their impact.

Daykin A, Selman LE, Cramer H, McCann S, Shorter GW, Sydes MR, Gamble C, Macefield R, Lane JA, Shaw A.

Trials. 2017 Dec 22;18(1):612. doi: 10.1186/s13063-017-2305-9.


A cohort examination to establish reporting of the remit and function of Trial Steering Committees in randomised controlled trials.

Conroy EJ, Arch B, Harman NL, Lane JA, Lewis SC, Norrie J, Sydes MR, Gamble C.

Trials. 2017 Dec 8;18(1):590. doi: 10.1186/s13063-017-2300-1.


Prostate-specific antigen (PSA) testing of men in UK general practice: a 10-year longitudinal cohort study.

Young GJ, Harrison S, Turner EL, Walsh EI, Oliver SE, Ben-Shlomo Y, Evans S, Lane JA, Neal DE, Hamdy FC, Donovan JL, Martin RM, Metcalfe C.

BMJ Open. 2017 Oct 30;7(10):e017729. doi: 10.1136/bmjopen-2017-017729.


Barriers and facilitators to healthy lifestyle and acceptability of a dietary and physical activity intervention among African Caribbean prostate cancer survivors in the UK: a qualitative study.

Er V, Lane JA, Martin RM, Persad R, Chinegwundoh F, Njoku V, Sutton E.

BMJ Open. 2017 Oct 15;7(10):e017217. doi: 10.1136/bmjopen-2017-017217.


Acceptability of dietary and physical activity lifestyle modification for men following radiotherapy or radical prostatectomy for localised prostate cancer: a qualitative investigation.

Hackshaw-McGeagh LE, Sutton E, Persad R, Aning J, Bahl A, Koupparis A, Millett C, Martin RM, Lane JA.

BMC Urol. 2017 Oct 10;17(1):94. doi: 10.1186/s12894-017-0284-5.


Statistical analysis plan for the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM).

Young GJ, Lewis AL, Lane JA, Winton HL, Drake MJ, Blair PS.

Trials. 2017 Oct 3;18(1):455. doi: 10.1186/s13063-017-2206-y.


Post-diagnosis serum insulin-like growth factors in relation to dietary and lifestyle changes in the Prostate testing for cancer and Treatment (ProtecT) trial.

Er V, Biernacka K, Simpkin AJ, Martin RM, Jeffreys M, Emmett P, Gilbert R, Avery KNL, Walsh E, Davis M, Donovan JL, Neal DE, Hamdy FC, Holly JMP, Lane JA.

Cancer Causes Control. 2017 Aug;28(8):877-888. doi: 10.1007/s10552-017-0910-2. Epub 2017 Jun 23.


Prostate cancer risk related to foods, food groups, macronutrients and micronutrients derived from the UK Dietary Cohort Consortium food diaries.

Lane JA, Oliver SE, Appleby PN, Lentjes MA, Emmett P, Kuh D, Stephen A, Brunner EJ, Shipley MJ, Hamdy FC, Neal DE, Donovan JL, Khaw KT, Key TJ.

Eur J Clin Nutr. 2017 Apr;71(4):567. doi: 10.1038/ejcn.2017.17. Epub 2017 Mar 15. No abstract available.


The feasibility of the Prostate cancer: Evidence of Exercise and Nutrition Trial (PrEvENT) dietary and physical activity modifications: a qualitative study.

Shingler E, Hackshaw-McGeagh L, Robles L, Persad R, Koupparis A, Rowe E, Shiridzinomwa C, Bahl A, Martin RM, Lane JA.

Trials. 2017 Mar 7;18(1):106. doi: 10.1186/s13063-017-1828-4.


The provision of dietary and physical activity advice for men diagnosed with prostate cancer: a qualitative study of the experiences and views of health care professionals, patients and partners.

Sutton E, Hackshaw-McGeagh LE, Aning J, Bahl A, Koupparis A, Persad R, Martin RM, Lane JA.

Cancer Causes Control. 2017 Apr;28(4):319-329. doi: 10.1007/s10552-017-0861-7. Epub 2017 Feb 20.


Replicatively senescent human fibroblasts reveal a distinct intracellular metabolic profile with alterations in NAD+ and nicotinamide metabolism.

James EL, Lane JA, Michalek RD, Karoly ED, Parkinson EK.

Sci Rep. 2016 Dec 7;6:38489. doi: 10.1038/srep38489.


Investigating the prostate specific antigen, body mass index and age relationship: is an age-BMI-adjusted PSA model clinically useful?

Harrison S, Tilling K, Turner EL, Lane JA, Simpkin A, Davis M, Donovan J, Hamdy FC, Neal DE, Martin RM.

Cancer Causes Control. 2016 Dec;27(12):1465-1474. Epub 2016 Nov 9.


The Role of Oligosaccharides in Host-Microbial Interactions for Human Health.

Ross SA, Lane JA, Marotta M, Kavanaugh D, Ryan JT, Joshi L, Hickey RM.

J Clin Gastroenterol. 2016 Nov/Dec;50 Suppl 2, Proceedings from the 8th Probiotics, Prebiotics & New Foods for Microbiota and Human Health meeting held in Rome, Italy on September 13-15, 2015:S131-S132.


Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial.

Walsh EI, Turner EL, Lane JA, Donovan JL, Neal DE, Hamdy FC, Martin RM; the CAP & ProtecT Trial Groups; Investigators; Research staff; Management Committee; CAP & ProtecT Trial Steering Committee; Data Monitoring Committee; Administrative staff.

Trials. 2016 Oct 13;17(1):497.


Mortality Among Men with Advanced Prostate Cancer Excluded from the ProtecT Trial.

Johnston TJ, Shaw GL, Lamb AD, Parashar D, Greenberg D, Xiong T, Edwards AL, Gnanapragasam V, Holding P, Herbert P, Davis M, Mizielinsk E, Lane JA, Oxley J, Robinson M, Mason M, Staffurth J, Bollina P, Catto J, Doble A, Doherty A, Gillatt D, Kockelbergh R, Kynaston H, Prescott S, Paul A, Powell P, Rosario D, Rowe E, Donovan JL, Hamdy FC, Neal DE; ProtecT study group.

Eur Urol. 2017 Mar;71(3):381-388. doi: 10.1016/j.eururo.2016.09.040. Epub 2016 Oct 6.


Is Your Dental Adhesive Forgiving? How to Address Challenges.

Lane JA, Hughey SJ, Gregory PN, Versluis-Tantbirojn D, Simon JF, Harrison J, Versluis A.

Compend Contin Educ Dent. 2016 Oct;37(9):621-625; quiz 626.


Delayed Application Effect on Bond Strength of a Unidose Bonding Adhesive.

Lane JA, Hughey SJ, Gregory PN, Versluis-Tantbirojn D, Simon JF, Harrison J, Versluis A.

Compend Contin Educ Dent. 2016 Oct;37(9):e5-e8.


Prostate cancer risk related to foods, food groups, macronutrients and micronutrients derived from the UK Dietary Cohort Consortium food diaries.

Lane JA, Oliver SE, Appleby PN, Lentjes MA, Emmett P, Kuh D, Stephen A, Brunner EJ, Shipley MJ, Hamdy FC, Neal DE, Donovan JL, Khaw KT, Key TJ.

Eur J Clin Nutr. 2017 Feb;71(2):274-283. doi: 10.1038/ejcn.2016.162. Epub 2016 Sep 28. Erratum in: Eur J Clin Nutr. 2017 Apr;71(4):567.


Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.

Donovan JL, Hamdy FC, Lane JA, Mason M, Metcalfe C, Walsh E, Blazeby JM, Peters TJ, Holding P, Bonnington S, Lennon T, Bradshaw L, Cooper D, Herbert P, Howson J, Jones A, Lyons N, Salter E, Thompson P, Tidball S, Blaikie J, Gray C, Bollina P, Catto J, Doble A, Doherty A, Gillatt D, Kockelbergh R, Kynaston H, Paul A, Powell P, Prescott S, Rosario DJ, Rowe E, Davis M, Turner EL, Martin RM, Neal DE; ProtecT Study Group*.

N Engl J Med. 2016 Oct 13;375(15):1425-1437. doi: 10.1056/NEJMoa1606221. Epub 2016 Sep 14.


10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer.

Hamdy FC, Donovan JL, Lane JA, Mason M, Metcalfe C, Holding P, Davis M, Peters TJ, Turner EL, Martin RM, Oxley J, Robinson M, Staffurth J, Walsh E, Bollina P, Catto J, Doble A, Doherty A, Gillatt D, Kockelbergh R, Kynaston H, Paul A, Powell P, Prescott S, Rosario DJ, Rowe E, Neal DE; ProtecT Study Group.

N Engl J Med. 2016 Oct 13;375(15):1415-1424. doi: 10.1056/NEJMoa1606220. Epub 2016 Sep 14.


Radiotherapy for Prostate Cancer: is it 'what you do' or 'the way that you do it'? A UK Perspective on Technique and Quality Assurance.

Mason MD, Moore R, Jones G, Lewis G, Donovan JL, Neal DE, Hamdy FC, Lane JA, Staffurth JN; ProtecT Study Group.

Clin Oncol (R Coll Radiol). 2016 Sep;28(9):e92-e100. doi: 10.1016/j.clon.2016.05.011. Epub 2016 Jul 12.


What are the roles and valued attributes of a Trial Steering Committee? Ethnographic study of eight clinical trials facing challenges.

Daykin A, Selman LE, Cramer H, McCann S, Shorter GW, Sydes MR, Gamble C, Macefield R, Lane JA, Shaw A.

Trials. 2016 Jul 1;17(1):307. doi: 10.1186/s13063-016-1425-y.


Temporal alterations in the bovine buttermilk glycome from parturition to milk maturation.

Ross SA, Gerlach JQ, Gill SK, Lane JA, Kilcoyne M, Hickey RM, Joshi L.

Food Chem. 2016 Nov 15;211:329-38. doi: 10.1016/j.foodchem.2016.05.027. Epub 2016 May 6.


Contemporary accuracy of death certificates for coding prostate cancer as a cause of death: Is reliance on death certification good enough? A comparison with blinded review by an independent cause of death evaluation committee.

Turner EL, Metcalfe C, Donovan JL, Noble S, Sterne JA, Lane JA, I Walsh E, Hill EM, Down L, Ben-Shlomo Y, Oliver SE, Evans S, Brindle P, Williams NJ, Hughes LJ, Davies CF, Ng SY, Neal DE, Hamdy FC, Albertsen P, Reid CM, Oxley J, McFarlane J, Robinson MC, Adolfsson J, Zietman A, Baum M, Koupparis A, Martin RM.

Br J Cancer. 2016 Jun 28;115(1):90-4. doi: 10.1038/bjc.2016.162. Epub 2016 Jun 2.

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