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Items: 1 to 50 of 221

1.

Oxygen-mediated control of the keratinocyte proliferation-differentiation axis.

Koh R, Szeverényi I, Lee B, Denil SLIJ, John Lim SY, Benny PA, Grasset N, Tan BK, Lane EB.

J Invest Dermatol. 2019 Jul 5. pii: S0022-202X(19)31852-4. doi: 10.1016/j.jid.2019.05.030. [Epub ahead of print] No abstract available.

PMID:
31283927
2.

Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A.

Kolundzic N, Khurana P, Devito L, Donne M, Hobbs C, Jeriha J, Wong XFCC, Common JAE, Lane EB, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D.

Stem Cell Res. 2019 Jul;38:101462. doi: 10.1016/j.scr.2019.101462. Epub 2019 May 13.

3.

Array-based sequencing of filaggrin gene for comprehensive detection of disease-associated variants.

Wong XFCC, Denil SLIJ, Foo JN, Chen H, Tay ASL, Haines RL, Tang MBY, McLean WHI, Sandilands A, Smith FJD, Lane EB, Liu J, Common JEA.

J Allergy Clin Immunol. 2018 Feb;141(2):814-816. doi: 10.1016/j.jaci.2017.10.001. Epub 2017 Oct 19. No abstract available.

4.

EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis.

Sundaram GM, Ismail HM, Bashir M, Muhuri M, Vaz C, Nama S, Ow GS, Vladimirovna IA, Ramalingam R, Burke B, Tanavde V, Kuznetsov V, Lane EB, Sampath P.

J Exp Med. 2017 Oct 2;214(10):2889-2900. doi: 10.1084/jem.20170354. Epub 2017 Aug 21.

5.

Keratin gene mutations influence the keratinocyte response to DNA damage and cytokine induced apoptosis.

Zupancic T, Sersa G, Törmä H, Lane EB, Herrmann H, Komel R, Liovic M.

Arch Dermatol Res. 2017 Sep;309(7):587-593. doi: 10.1007/s00403-017-1757-9. Epub 2017 Jun 24.

PMID:
28647894
6.

Modeling the Structure of Keratin 1 and 10 Terminal Domains and their Misassembly in Keratoderma.

Badowski C, Sim AYL, Verma C, Szeverényi I, Natesavelalar C, Terron-Kwiatkowski A, Harper J, O'Toole EA, Lane EB.

J Invest Dermatol. 2017 Sep;137(9):1914-1923. doi: 10.1016/j.jid.2017.03.038. Epub 2017 May 16.

7.

Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes.

Kriszt R, Arai S, Itoh H, Lee MH, Goralczyk AG, Ang XM, Cypess AM, White AP, Shamsi F, Xue R, Lee JY, Lee SC, Hou Y, Kitaguchi T, Sudhaharan T, Ishiwata S, Lane EB, Chang YT, Tseng YH, Suzuki M, Raghunath M.

Sci Rep. 2017 May 3;7(1):1383. doi: 10.1038/s41598-017-00291-9.

8.

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.

Kumar D, Puan KJ, Andiappan AK, Lee B, Westerlaken GH, Haase D, Melchiotti R, Li Z, Yusof N, Lum J, Koh G, Foo S, Yeong J, Alves AC, Pekkanen J, Sun LD, Irwanto A, Fairfax BP, Naranbhai V, Common JE, Tang M, Chuang CK, Jarvelin MR, Knight JC, Zhang X, Chew FT, Prabhakar S, Jianjun L, Wang Y, Zolezzi F, Poidinger M, Lane EB, Meyaard L, Rötzschke O.

Genome Med. 2017 Feb 20;9(1):18. doi: 10.1186/s13073-017-0404-6.

9.

Late-Onset Multiple Self-Healing Squamous Epithelioma Ferguson-Smith Recurrence Induced by Radiotherapy.

Feldmeyer L, Szeverényi I, Mandallaz M, Lane EB, Hohl D.

Case Rep Dermatol. 2016 Dec 1;8(3):344-349. doi: 10.1159/000447481. eCollection 2016 Sep-Dec.

10.

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation.

Zhong FL, Mamaï O, Sborgi L, Boussofara L, Hopkins R, Robinson K, Szeverényi I, Takeichi T, Balaji R, Lau A, Tye H, Roy K, Bonnard C, Ahl PJ, Jones LA, Baker PJ, Lacina L, Otsuka A, Fournie PR, Malecaze F, Lane EB, Akiyama M, Kabashima K, Connolly JE, Masters SL, Soler VJ, Omar SS, McGrath JA, Nedelcu R, Gribaa M, Denguezli M, Saad A, Hiller S, Reversade B.

Cell. 2016 Sep 22;167(1):187-202.e17. doi: 10.1016/j.cell.2016.09.001.

11.
12.

Improving 2D and 3D Skin In Vitro Models Using Macromolecular Crowding.

Benny P, Badowski C, Lane EB, Raghunath M.

J Vis Exp. 2016 Aug 22;(114). doi: 10.3791/53642.

13.

Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare.

Chng KR, Tay AS, Li C, Ng AH, Wang J, Suri BK, Matta SA, McGovern N, Janela B, Wong XF, Sio YY, Au BV, Wilm A, De Sessions PF, Lim TC, Tang MB, Ginhoux F, Connolly JE, Lane EB, Chew FT, Common JE, Nagarajan N.

Nat Microbiol. 2016 Jul 11;1(9):16106. doi: 10.1038/nmicrobiol.2016.106.

PMID:
27562258
14.

Direct organelle thermometry with fluorescence lifetime imaging microscopy in single myotubes.

Itoh H, Arai S, Sudhaharan T, Lee SC, Chang YT, Ishiwata S, Suzuki M, Lane EB.

Chem Commun (Camb). 2016 Mar 25;52(24):4458-61. doi: 10.1039/c5cc09943a.

PMID:
26977478
15.

Assays to Study Consequences of Cytoplasmic Intermediate Filament Mutations: The Case of Epidermal Keratins.

Tan TS, Ng YZ, Badowski C, Dang T, Common JE, Lacina L, Szeverényi I, Lane EB.

Methods Enzymol. 2016;568:219-53. doi: 10.1016/bs.mie.2015.09.030. Epub 2016 Jan 6.

PMID:
26795473
16.

Breast cancer resistance protein identifies clonogenic keratinocytes in human interfollicular epidermis.

Ma D, Chua AW, Yang E, Teo P, Ting Y, Song C, Lane EB, Lee ST.

Stem Cell Res Ther. 2015 Mar 24;6:43. doi: 10.1186/s13287-015-0032-2.

17.

Characterization of fetal keratinocytes, showing enhanced stem cell-like properties: a potential source of cells for skin reconstruction.

Tan KK, Salgado G, Connolly JE, Chan JK, Lane EB.

Stem Cell Reports. 2014 Aug 12;3(2):324-38. doi: 10.1016/j.stemcr.2014.06.005. Epub 2014 Jul 10.

18.

Making more matrix: enhancing the deposition of dermal-epidermal junction components in vitro and accelerating organotypic skin culture development, using macromolecular crowding.

Benny P, Badowski C, Lane EB, Raghunath M.

Tissue Eng Part A. 2015 Jan;21(1-2):183-92. doi: 10.1089/ten.TEA.2013.0784. Epub 2014 Oct 9.

19.

Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease.

Zupancic T, Stojan J, Lane EB, Komel R, Bedina-Zavec A, Liovic M.

PLoS One. 2014 Jun 10;9(6):e99398. doi: 10.1371/journal.pone.0099398. eCollection 2014. Erratum in: PLoS One. 2014;9(7):e104122.

20.

Generation and characterisation of keratin 7 (K7) knockout mice.

Sandilands A, Smith FJ, Lunny DP, Campbell LE, Davidson KM, MacCallum SF, Corden LD, Christie L, Fleming S, Lane EB, McLean WH.

PLoS One. 2013 May 31;8(5):e64404. doi: 10.1371/journal.pone.0064404. Print 2013.

21.

Lamin B1 fluctuations have differential effects on cellular proliferation and senescence.

Dreesen O, Chojnowski A, Ong PF, Zhao TY, Common JE, Lunny D, Lane EB, Lee SJ, Vardy LA, Stewart CL, Colman A.

J Cell Biol. 2013 Mar 4;200(5):605-17. doi: 10.1083/jcb.201206121. Epub 2013 Feb 25.

22.

'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing.

Sundaram GM, Common JE, Gopal FE, Srikanta S, Lakshman K, Lunny DP, Lim TC, Tanavde V, Lane EB, Sampath P.

Nature. 2013 Mar 7;495(7439):103-6. doi: 10.1038/nature11890. Epub 2013 Feb 10.

PMID:
23395958
23.

Keratins and disease at a glance.

Haines RL, Lane EB.

J Cell Sci. 2012 Sep 1;125(Pt 17):3923-8. doi: 10.1242/jcs.099655. Review. No abstract available.

24.

Ionizing radiation induces a dramatic persistence of p53 protein accumulation and DNA damage signaling in mutant p53 zebrafish.

Guo L, Liew HP, Camus S, Goh AM, Chee LL, Lunny DP, Lane EB, Lane DP.

Oncogene. 2013 Aug 22;32(34):4009-16. doi: 10.1038/onc.2012.409. Epub 2012 Oct 15.

PMID:
23069659
25.

Fibroblast-derived dermal matrix drives development of aggressive cutaneous squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa.

Ng YZ, Pourreyron C, Salas-Alanis JC, Dayal JH, Cepeda-Valdes R, Yan W, Wright S, Chen M, Fine JD, Hogg FJ, McGrath JA, Murrell DF, Leigh IM, Lane EB, South AP.

Cancer Res. 2012 Jul 15;72(14):3522-34. doi: 10.1158/0008-5472.CAN-11-2996. Epub 2012 May 7.

26.

The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes.

Beriault DR, Haddad O, McCuaig JV, Robinson ZJ, Russell D, Lane EB, Fudge DS.

PLoS One. 2012;7(2):e31320. doi: 10.1371/journal.pone.0031320. Epub 2012 Feb 21.

27.

Validation of GWAS loci for atopic dermatitis in a Singapore Chinese population.

Andiappan AK, Foo JN, Choy MW, Chen H, Common JE, Tang MB, van Bever HP, Giam YC, Suri BK, Ramani A, Nilkanth PP, Lane EB, Wang de Y, Chew FT, Liu J.

J Invest Dermatol. 2012 May;132(5):1505-7. doi: 10.1038/jid.2011.471. Epub 2012 Feb 9. No abstract available.

28.

Filaggrin mutations are associated with recurrent skin infection in Singaporean Chinese patients with atopic dermatitis.

Cai SC, Chen H, Koh WP, Common JE, van Bever HP, McLean WH, Lane EB, Giam YC, Tang MB.

Br J Dermatol. 2012 Jan;166(1):200-3. doi: 10.1111/j.1365-2133.2011.10541.x. Epub 2011 Nov 17.

PMID:
21790526
29.

Developmental expression of the fermitin/kindlin gene family in Xenopus laevis embryos.

Canning CA, Chan JS, Common JE, Lane EB, Jones CM.

Dev Dyn. 2011 Aug;240(8):1958-63. doi: 10.1002/dvdy.22683.

30.

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.

Chen H, Common JE, Haines RL, Balakrishnan A, Brown SJ, Goh CS, Cordell HJ, Sandilands A, Campbell LE, Kroboth K, Irvine AD, Goh DL, Tang MB, van Bever HP, Giam YC, McLean WH, Lane EB.

Br J Dermatol. 2011 Jul;165(1):106-14. doi: 10.1111/j.1365-2133.2011.10331.x.

PMID:
21428977
31.

Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1.

Goudie DR, D'Alessandro M, Merriman B, Lee H, Szeverényi I, Avery S, O'Connor BD, Nelson SF, Coats SE, Stewart A, Christie L, Pichert G, Friedel J, Hayes I, Burrows N, Whittaker S, Gerdes AM, Broesby-Olsen S, Ferguson-Smith MA, Verma C, Lunny DP, Reversade B, Lane EB.

Nat Genet. 2011 Feb 27;43(4):365-9. doi: 10.1038/ng.780.

PMID:
21358634
32.

Keratin 14-null cells as a model to test the efficacy of gene therapy approaches in epithelial cells.

D'Alessandro M, Coats SE, Jonkmann MF, Leigh IM, Lane EB.

J Invest Dermatol. 2011 Jul;131(7):1412-9. doi: 10.1038/jid.2011.19. Epub 2011 Feb 17. Erratum in: J Invest Dermatol. 2011 Jun;131(6):1388. Jonkmann, Marcel F [corrected to Jonkman, Marcel F].

33.

Filaggrin null mutations are not a protective factor for acne vulgaris.

Common JE, Brown SJ, Haines RL, Goh CS, Chen H, Balakrishnan A, Munro CS, Tan AW, Tan HH, Tang MB, Lane EB.

J Invest Dermatol. 2011 Jun;131(6):1378-80. doi: 10.1038/jid.2011.23. Epub 2011 Feb 17. No abstract available.

34.

Immunohistochemical localization of cytokeratins in the junctional region of ectoderm and endoderm.

Hosoya A, Kwak S, Kim EJ, Lunny DP, Lane EB, Cho SW, Jung HS.

Anat Rec (Hoboken). 2010 Nov;293(11):1864-72. doi: 10.1002/ar.21233.

35.

A novel mutation in the kinase domain of KIT in an Indian family with a mild piebaldism phenotype.

Chong KL, Common JE, Lane EB, Goh BK.

J Dermatol Sci. 2010 Sep;59(3):206-9. doi: 10.1016/j.jdermsci.2010.06.009. Epub 2010 Jul 8. No abstract available.

PMID:
20688482
36.

ERK involvement in resistance to apoptosis in keratinocytes with mutant keratin.

Russell D, Ross H, Lane EB.

J Invest Dermatol. 2010 Mar;130(3):671-81. doi: 10.1038/jid.2009.327. Epub 2009 Oct 22.

37.

A rare connexin 26 mutation in a patient with a forme fruste of keratitis-ichthyosis-deafness (KID) syndrome.

Neoh CY, Chen H, Ng SK, Lane EB, Common JE.

Int J Dermatol. 2009 Oct;48(10):1078-81.

PMID:
19785089
38.

Steatocystoma multiplex, oligodontia and partial persistent primary dentition associated with a novel keratin 17 mutation.

Gass JK, Wilson NJ, Smith FJ, Lane EB, McLean WH, Rytina E, Salvary I, Burrows NP.

Br J Dermatol. 2009 Dec;161(6):1396-8. doi: 10.1111/j.1365-2133.2009.09383.x. Epub 2009 Jul 31. No abstract available.

PMID:
19659471
39.

Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes.

Liovic M, D'Alessandro M, Tomic-Canic M, Bolshakov VN, Coats SE, Lane EB.

Exp Cell Res. 2009 Oct 15;315(17):2995-3003. doi: 10.1016/j.yexcr.2009.07.013. Epub 2009 Jul 17.

PMID:
19616543
40.

Keratin K6c mutations cause focal palmoplantar keratoderma.

Wilson NJ, Messenger AG, Leachman SA, O'Toole EA, Lane EB, McLean WH, Smith FJ.

J Invest Dermatol. 2010 Feb;130(2):425-9. doi: 10.1038/jid.2009.215. Epub 2009 Jul 16.

41.

Association of skin barrier genes within the PSORS4 locus is enriched in Singaporean Chinese with early-onset psoriasis.

Chen H, Toh TK, Szeverenyi I, Ong RT, Theng CT, McLean WH, Seielstad M, Lane EB.

J Invest Dermatol. 2009 Mar;129(3):606-14. doi: 10.1038/jid.2008.273. Epub 2008 Sep 11.

42.

The intermediate filament network in cultured human keratinocytes is remarkably extensible and resilient.

Fudge D, Russell D, Beriault D, Moore W, Lane EB, Vogl AW.

PLoS One. 2008 Jun 4;3(6):e2327. doi: 10.1371/journal.pone.0002327.

43.

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL.

J Dermatol Sci. 2008 Sep;51(3):151-7. doi: 10.1016/j.jdermsci.2008.04.003. Epub 2008 May 20. Review.

44.

Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines.

Liovic M, Lee B, Tomic-Canic M, D'Alessandro M, Bolshakov VN, Lane EB.

Exp Cell Res. 2008 Jun 10;314(10):2066-75. doi: 10.1016/j.yexcr.2008.02.020. Epub 2008 Mar 8.

PMID:
18410923
45.

Unique and recurrent mutations in the filaggrin gene in Singaporean Chinese patients with ichthyosis vulgaris.

Chen H, Ho JC, Sandilands A, Chan YC, Giam YC, Evans AT, Lane EB, McLean WH.

J Invest Dermatol. 2008 Jul;128(7):1669-75. doi: 10.1038/sj.jid.2008.2. Epub 2008 Jan 31. Erratum in: J Invest Dermatol. 2008 Oct;128(10):2545.

46.

The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases.

Szeverenyi I, Cassidy AJ, Chung CW, Lee BT, Common JE, Ogg SC, Chen H, Sim SY, Goh WL, Ng KW, Simpson JA, Chee LL, Eng GH, Li B, Lunny DP, Chuon D, Venkatesh A, Khoo KH, McLean WH, Lim YP, Lane EB.

Hum Mutat. 2008 Mar;29(3):351-60.

PMID:
18033728
47.

Molecular force spectroscopy of homophilic nectin-1 interactions.

Vedula SR, Lim TS, Hui S, Kausalya PJ, Lane EB, Rajagopal G, Hunziker W, Lim CT.

Biochem Biophys Res Commun. 2007 Nov 3;362(4):886-92. Epub 2007 Aug 28.

PMID:
17822670
48.

A spectrum of mutations in keratins K6a, K16 and K17 causing pachyonychia congenita.

Liao H, Sayers JM, Wilson NJ, Irvine AD, Mellerio JE, Baselga E, Bayliss SJ, Uliana V, Fimiani M, Lane EB, McLean WH, Leachman SA, Smith FJ.

J Dermatol Sci. 2007 Dec;48(3):199-205. Epub 2007 Aug 24.

PMID:
17719747
49.

Ninein is released from the centrosome and moves bi-directionally along microtubules.

Moss DK, Bellett G, Carter JM, Liovic M, Keynton J, Prescott AR, Lane EB, Mogensen MM.

J Cell Sci. 2007 Sep 1;120(Pt 17):3064-74. Epub 2007 Aug 14.

50.

Detection of the p53 response in zebrafish embryos using new monoclonal antibodies.

Lee KC, Goh WL, Xu M, Kua N, Lunny D, Wong JS, Coomber D, Vojtesek B, Lane EB, Lane DP.

Oncogene. 2008 Jan 24;27(5):629-40. Epub 2007 Aug 6.

PMID:
17684488

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