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Items: 1 to 50 of 1996

1.

The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors.

Kannan S, Partridge AW, Lane DP, Verma CS.

Int J Mol Sci. 2019 Nov 28;20(23). pii: E5996. doi: 10.3390/ijms20235996.

2.

Volatilisation of major, minor, and trace elements during thermal processing of fly ashes from waste- and wood-fired power plants in oxidising and reducing gas atmospheres.

Lane DJ, Sippula O, Koponen H, Heimonen M, Peräniemi S, Lähde A, Kinnunen NM, Nivajärvi T, Shurpali N, Jokiniemi J.

Waste Manag. 2019 Nov 30;102:698-709. doi: 10.1016/j.wasman.2019.11.025. [Epub ahead of print]

PMID:
31794929
3.

Simultaneous measurement of p53:Mdm2 and p53:Mdm4 protein-protein interactions in whole cells using fluorescence labelled foci.

Frosi Y, Inoue K, Ramlan SR, Lane DP, Watanabe T, Brown CJ.

Sci Rep. 2019 Nov 29;9(1):17933. doi: 10.1038/s41598-019-54123-z.

4.

Monocular Vision Loss: A Rare Cause.

Lane D, Pomeranz K, Findlay S, Miller D.

Clin Pract Cases Emerg Med. 2019 Mar 27;3(4):436-437. doi: 10.5811/cpcem.2019.6.43224. eCollection 2019 Nov.

5.

Alpha-synuclein is strategically positioned for afferent modulation of midbrain dopamine neurons and is essential for cocaine preference.

Trubetckaia O, Lane AE, Qian L, Zhou P, Lane DA.

Commun Biol. 2019 Nov 15;2:418. doi: 10.1038/s42003-019-0651-8. eCollection 2019.

6.

Validation of the modified Microlife blood pressure monitor in patients with paroxysmal atrial fibrillation.

Huppertz N, Lip GYH, Lane DA.

Clin Res Cardiol. 2019 Nov 7. doi: 10.1007/s00392-019-01567-y. [Epub ahead of print]

PMID:
31701215
7.

Guideline-Adherent Treatment for Stroke and Death in Atrial Fibrillation Patients From UK and Japanese AF Registries.

Miyazawa K, Ogawa H, Mazurek M, Shantsila E, Lane DA, Wolff A, Akao M, Lip GYH.

Circ J. 2019 Nov 25;83(12):2434-2442. doi: 10.1253/circj.CJ-19-0546. Epub 2019 Nov 6.

8.

The quantification of antibody elements and receptors subunit expression using qPCR: The design of VH, VL, CH, CL, FcR subunits primers for a more holistic view of the immune system.

Ling WL, Ng YL, Wipat A, Lane DP, Gan SK.

J Immunol Methods. 2019 Nov 1:112683. doi: 10.1016/j.jim.2019.112683. [Epub ahead of print]

9.

Ascorbate and Tumor Cell Iron Metabolism: The Evolving Story and its Link to Pathology.

Bae DH, Gholam Azad M, Kalinowski DS, Lane DJR, Jansson PJ, Richardson DR.

Antioxid Redox Signal. 2019 Nov 1. doi: 10.1089/ars.2019.7903. [Epub ahead of print]

PMID:
31672021
10.

Understanding the Fate of Environmental Chemicals Inside Living Organisms: NMR-Based 13C Isotopic Suppression Selects Only the Molecule of Interest within 13C-Enriched Organisms.

Lane D, Liaghati Mobarhan Y, Soong R, Ning P, Bermel W, Tabatabaei Anaraki M, Wu B, Heumann H, Gundy M, Boenisch H, Jeong TY, Kovacevic V, Simpson MJ, Simpson AJ.

Anal Chem. 2019 Dec 3;91(23):15000-15008. doi: 10.1021/acs.analchem.9b03596. Epub 2019 Nov 13.

PMID:
31670507
11.

The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells.

Mortensen ACL, Spiegelberg D, Brown CJ, Lane DP, Nestor M.

Front Oncol. 2019 Sep 19;9:923. doi: 10.3389/fonc.2019.00923. eCollection 2019.

12.

Functionalized Resins for the Synthesis of Peptide Alcohols.

Ferrer-Gago FJ, Koh LQ, Lane DP.

Chemistry. 2019 Oct 14. doi: 10.1002/chem.201903965. [Epub ahead of print]

PMID:
31609031
13.

Humanising medicine: teaching on tri-morbidity using expert patient narratives in medical education.

Player E, Gure-Klinke H, North S, Hanson S, Lane D, Culyer G, Rodrigues V.

Educ Prim Care. 2019 Oct 3:1-7. doi: 10.1080/14739879.2019.1670097. [Epub ahead of print]

PMID:
31580229
14.

Warfarin Therapy and Improved Anticoagulation Control by Patient Self-Management.

Ritchie LA, Penson PE, Lane DA.

Thromb Haemost. 2019 Oct;19(10):1550-1552. doi: 10.1055/s-0039-1696982. Epub 2019 Sep 29. No abstract available.

PMID:
31564055
15.

Global Use of Idarucizumab in Clinical Practice: Outcomes of the RE-VECTO Surveillance Program.

Fanikos J, Murwin D, Gruenenfelder F, Tartakovsky I, França LR, Reilly PA, Kermer P, Wowern FV, Lane DA, Butcher K.

Thromb Haemost. 2019 Aug 30. doi: 10.1055/s-0039-1695771. [Epub ahead of print]

16.

Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin.

Ahnström J, Gierula M, Temenu J, Laffan MA, Lane DA.

J Thromb Haemost. 2019 Aug 29. doi: 10.1111/jth.14627. [Epub ahead of print]

PMID:
31466141
17.

Metabolic Profiling Using In Vivo High Field Flow NMR.

Anaraki MT, Lane D, Bastawrous M, Jenne A, Simpson AJ.

Methods Mol Biol. 2019;2037:395-409. doi: 10.1007/978-1-4939-9690-2_22.

PMID:
31463857
18.

Selective Amino Acid-Only in Vivo NMR: A Powerful Tool To Follow Stress Processes.

Lane D, Soong R, Bermel W, Ning P, Dutta Majumdar R, Tabatabaei-Anaraki M, Heumann H, Gundy M, Bönisch H, Liaghati Mobarhan Y, Simpson MJ, Simpson AJ.

ACS Omega. 2019 May 22;4(5):9017-9028. doi: 10.1021/acsomega.9b00931. eCollection 2019 May 31.

19.

Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase.

Koh XY, Koh XH, Hwang LA, Ferrer FJ, Rahmat SAB, Lama D, Lane DP.

Oncogene. 2019 Nov;38(48):7342-7356. doi: 10.1038/s41388-019-0946-8. Epub 2019 Aug 15.

PMID:
31417186
20.

Baggage scanners and their use as an imaging resource in mass fatality incidents.

D'Arcy G, Márquez-Grant N, Lane DW.

Int J Legal Med. 2019 Aug 8. doi: 10.1007/s00414-019-02132-y. [Epub ahead of print]

PMID:
31396702
21.

How to lose tumor suppression.

Lane DP.

Science. 2019 Aug 9;365(6453):539-540. doi: 10.1126/science.aay4319. No abstract available.

PMID:
31395768
22.

Integrated care for the management of atrial fibrillation: what are the key components and important outcomes?

Lane DA, Lip GYH.

Europace. 2019 Aug 7. pii: euz211. doi: 10.1093/europace/euz211. [Epub ahead of print] No abstract available.

PMID:
31390468
23.

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex.

Gierula M, Salles-Crawley II, Santamaria S, Teraz-Orosz A, Crawley JTB, Lane DA, Ahnström J.

J Thromb Haemost. 2019 Dec;17(12):2056-2068. doi: 10.1111/jth.14594. Epub 2019 Aug 9.

PMID:
31364267
24.

Low-Fat Dietary Pattern and Cancer Mortality in the Women's Health Initiative (WHI) Randomized Controlled Trial.

Chlebowski RT, Anderson GL, Manson JE, Prentice RL, Aragaki AK, Snetselaar L, Beresford SAA, Kuller LH, Johnson K, Lane D, Luo J, Rohan TE, Jiao L, Barac A, Womack C, Coday M, Datta M, Thomson CA.

JNCI Cancer Spectr. 2019 Jan 7;2(4):pky065. doi: 10.1093/jncics/pky065. eCollection 2018 Oct.

25.

Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis.

Santamaria S, Yamamoto K, Teraz-Orosz A, Koch C, Apte SS, de Groot R, Lane DA, Ahnström J.

Sci Rep. 2019 Jul 29;9(1):10914. doi: 10.1038/s41598-019-47494-w.

26.

Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function.

Crawley JTB, Zalli A, Monkman JH, Petri A, Lane DA, Ahnstrӧm J, Salles-Crawley II.

J Thromb Haemost. 2019 Nov;17(11):1935-1949. doi: 10.1111/jth.14593. Epub 2019 Aug 26.

PMID:
31351019
27.

Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice.

Pickel VM, Bourie F, Chan J, Mackie K, Lane DA, Wang G.

Neuropsychopharmacology. 2019 Jul 19. doi: 10.1038/s41386-019-0466-9. [Epub ahead of print]

PMID:
31323660
28.

Intratumour heterogeneity of p53 expression; causes and consequences.

Xue Y, San Luis B, Lane DP.

J Pathol. 2019 Nov;249(3):274-285. doi: 10.1002/path.5328. Epub 2019 Aug 27. Review.

PMID:
31322742
29.

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles.

Yuen TY, Brown CJ, Xue Y, Tan YS, Ferrer Gago FJ, Lee XE, Neo JY, Thean D, Kaan HYK, Partridge AW, Verma CS, Lane DP, Johannes CW.

Chem Sci. 2019 May 30;10(26):6457-6466. doi: 10.1039/c9sc01456j. eCollection 2019 Jul 14.

30.

Patients' Perceptions of Atrial Fibrillation, Stroke Risk, and Oral Anticoagulation Treatment: An International Survey.

Lane DA, Meyerhoff J, Rohner U, Lip GYH.

TH Open. 2018 Jul 5;2(3):e233-e241. doi: 10.1055/s-0038-1666803. eCollection 2018 Jul.

31.

Educational Impact on Apixaban Adherence in Atrial Fibrillation (the AEGEAN STUDY): A Randomized Clinical Trial.

Montalescot G, Brotons C, Cosyns B, Crijns HJ, D'Angelo A, Drouet L, Eberli F, Lane DA, Besse B, Chan A, Vicaut E, Darius H; AEGEAN Study Investigators.

Am J Cardiovasc Drugs. 2019 Jun 26. doi: 10.1007/s40256-019-00356-2. [Epub ahead of print]

PMID:
31243691
32.

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties.

Partridge AW, Kaan HYK, Juang YC, Sadruddin A, Lim S, Brown CJ, Ng S, Thean D, Ferrer F, Johannes C, Yuen TY, Kannan S, Aronica P, Tan YS, Pradhan MR, Verma CS, Hochman J, Chen S, Wan H, Ha S, Sherborne B, Lane DP, Sawyer TK.

Molecules. 2019 Jun 20;24(12). pii: E2292. doi: 10.3390/molecules24122292.

33.

p53: updates on mechanisms, biology and therapy (I).

Lane DP, Verma CS.

J Mol Cell Biol. 2019 Mar 1;11(3):185-186. doi: 10.1093/jmcb/mjz017. No abstract available.

PMID:
31222355
34.

p53: updates on mechanisms, biology and therapy (II).

Lane DP, Verma CS.

J Mol Cell Biol. 2019 Apr 1;11(4):265-266. doi: 10.1093/jmcb/mjz018. No abstract available.

PMID:
31222348
35.

Assessing Severity of Illness in Patients Transported to Hospital by Paramedics: External Validation of 3 Prognostic Scores.

Lane DJ, Wunsch H, Saskin R, Cheskes S, Lin S, Morrison LJ, Scales DC.

Prehosp Emerg Care. 2019 Jul 15:1-9. doi: 10.1080/10903127.2019.1632998. [Epub ahead of print]

PMID:
31210571
36.

Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens.

Scarff JM, Waidyarachchi SL, Meyer CJ, Lane DJ, Chai W, Lemmon MM, Liu J, Butler MM, Bowlin TL, Lee RE, Panchal RG.

J Antibiot (Tokyo). 2019 Sep;72(9):693-701. doi: 10.1038/s41429-019-0194-8. Epub 2019 Jun 4.

37.

Classification versus Prediction of Mortality Risk using the SIRS and qSOFA Scores in Patients with Infection Transported by Paramedics.

Lane DJ, Lin S, Scales DC.

Prehosp Emerg Care. 2019 Jun 19:1-8. doi: 10.1080/10903127.2019.1624901. [Epub ahead of print]

PMID:
31140890
38.

Characterization of Hydration Properties in Structural Ensembles of Biomolecules.

Pradhan MR, Nguyen MN, Kannan S, Fox SJ, Kwoh CK, Lane DP, Verma CS.

J Chem Inf Model. 2019 Jul 22;59(7):3316-3329. doi: 10.1021/acs.jcim.8b00453. Epub 2019 Jun 17.

PMID:
31140800
39.

Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo.

Xue Y, Barker N, Hoon S, He P, Thakur T, Abdeen SR, Maruthappan P, Ghadessy FJ, Lane DP.

Cancer Res. 2019 Jul 15;79(14):3595-3607. doi: 10.1158/0008-5472.CAN-18-3744. Epub 2019 May 28.

PMID:
31138526
40.

Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly.

Frosi Y, Usher R, Lian DTG, Lane DP, Brown CJ.

BMC Biol. 2019 May 22;17(1):40. doi: 10.1186/s12915-019-0658-0.

41.

Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

Højen AA, Søgaard M, Melgaard L, Lane DA, Sørensen EE, Goldhaber SZ, Larsen TB.

BMJ Open. 2019 May 14;9(5):e026159. doi: 10.1136/bmjopen-2018-026159.

42.

Strategy to Identify Paramedic Transported Sepsis Cases in an Emergency Department Administrative Database.

Lane DJ, Blanchard IE, Cheskes S, Lazarenko G, Lin S, Morrison LJ, Saskin R, Seymour CW, Wunsch H, Scales DC.

Prehosp Emerg Care. 2019 May 31:1-9. doi: 10.1080/10903127.2019.1611978. [Epub ahead of print]

PMID:
31046502
43.

Objective measures of non-adherence in cardiometabolic diseases: a review focused on urine biochemical screening.

Lane D, Patel P, Khunti K, Gupta P.

Patient Prefer Adherence. 2019 Apr 12;13:537-547. doi: 10.2147/PPA.S162215. eCollection 2019. Review.

44.

Anticoagulation for Atrial Fibrillation in Older Adults-Using Big Data for Big Questions.

Quinn TJ, Lane DA.

Thromb Haemost. 2019 Jun;119(6):855-857. doi: 10.1055/s-0039-1688482. Epub 2019 Apr 30. No abstract available.

PMID:
31041792
45.

Stroke Prevention, Evaluation of Bleeding Risk, and Anticoagulant Treatment Management in Atrial Fibrillation Contemporary International Guidelines.

Proietti M, Lane DA, Boriani G, Lip GYH.

Can J Cardiol. 2019 May;35(5):619-633. doi: 10.1016/j.cjca.2019.02.009. Epub 2019 Feb 21. Review.

PMID:
31030864
46.

Guardian of Genome Editing.

Ho T, Lane DP.

CRISPR J. 2018 Aug;1:258-260. doi: 10.1089/crispr.2018.29021.dal. No abstract available.

PMID:
31021215
47.

Imaging features of triple-negative breast cancers according to androgen receptor status.

Candelaria RP, Adrada BE, Wei W, Thompson AM, Santiago L, Lane DL, Huang ML, Arribas EM, Rauch GM, Symmans WF, Gilcrease MZ, Huo L, Lim B, Ueno NT, Moulder SL, Yang WT.

Eur J Radiol. 2019 May;114:167-174. doi: 10.1016/j.ejrad.2019.03.017. Epub 2019 Mar 21.

PMID:
31005169
48.

Mobile Health (mHealth) technology for improved screening, patient involvement and optimising integrated care in atrial fibrillation: The mAFA (mAF-App) II randomised trial.

Guo Y, Lane DA, Wang L, Chen Y, Lip GYH; mAF-App II Trial investigators.

Int J Clin Pract. 2019 Jul;73(7):e13352. doi: 10.1111/ijcp.13352. Epub 2019 Jun 3.

PMID:
31002434
49.

Diet and mitochondrial DNA haplotype of a sperm whale (Physeter macrocephalus) found dead off Jurong Island, Singapore.

Chua MAH, Lane DJW, Ooi SK, Tay SHX, Kubodera T.

PeerJ. 2019 Apr 5;7:e6705. doi: 10.7717/peerj.6705. eCollection 2019.

50.

Understanding p53 functions through p53 antibodies.

Sabapathy K, Lane DP.

J Mol Cell Biol. 2019 Apr 1;11(4):317-329. doi: 10.1093/jmcb/mjz010.

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