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Items: 1 to 50 of 1982

1.

Global Use of Idarucizumab in Clinical Practice: Outcomes of the RE-VECTO Surveillance Program.

Fanikos J, Murwin D, Gruenenfelder F, Tartakovsky I, França LR, Reilly PA, Kermer P, Wowern FV, Lane DA, Butcher K.

Thromb Haemost. 2019 Aug 30. doi: 10.1055/s-0039-1695771. [Epub ahead of print]

2.

Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin.

Ahnström J, Gierula M, Temenu J, Laffan MA, Lane DA.

J Thromb Haemost. 2019 Aug 29. doi: 10.1111/jth.14627. [Epub ahead of print]

PMID:
31466141
3.

Metabolic Profiling Using In Vivo High Field Flow NMR.

Anaraki MT, Lane D, Bastawrous M, Jenne A, Simpson AJ.

Methods Mol Biol. 2019;2037:395-409. doi: 10.1007/978-1-4939-9690-2_22.

PMID:
31463857
4.

Selective Amino Acid-Only in Vivo NMR: A Powerful Tool To Follow Stress Processes.

Lane D, Soong R, Bermel W, Ning P, Dutta Majumdar R, Tabatabaei-Anaraki M, Heumann H, Gundy M, Bönisch H, Liaghati Mobarhan Y, Simpson MJ, Simpson AJ.

ACS Omega. 2019 May 22;4(5):9017-9028. doi: 10.1021/acsomega.9b00931. eCollection 2019 May 31.

5.

Therapeutic anti-cancer activity of antibodies targeting sulfhydryl bond constrained epitopes on unglycosylated RON receptor tyrosine kinase.

Koh XY, Koh XH, Hwang LA, Ferrer FJ, Rahmat SAB, Lama D, Lane DP.

Oncogene. 2019 Aug 15. doi: 10.1038/s41388-019-0946-8. [Epub ahead of print]

PMID:
31417186
6.

Baggage scanners and their use as an imaging resource in mass fatality incidents.

D'Arcy G, Márquez-Grant N, Lane DW.

Int J Legal Med. 2019 Aug 8. doi: 10.1007/s00414-019-02132-y. [Epub ahead of print]

PMID:
31396702
7.

How to lose tumor suppression.

Lane DP.

Science. 2019 Aug 9;365(6453):539-540. doi: 10.1126/science.aay4319. No abstract available.

PMID:
31395768
8.

Integrated care for the management of atrial fibrillation: what are the key components and important outcomes?

Lane DA, Lip GYH.

Europace. 2019 Aug 7. pii: euz211. doi: 10.1093/europace/euz211. [Epub ahead of print] No abstract available.

PMID:
31390468
9.

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex.

Gierula M, Salles-Crawley II, Santamaria S, Teraz-Orosz A, Crawley JTB, Lane DA, Ahnström J.

J Thromb Haemost. 2019 Jul 30. doi: 10.1111/jth.14594. [Epub ahead of print]

PMID:
31364267
10.

Low-Fat Dietary Pattern and Cancer Mortality in the Women's Health Initiative (WHI) Randomized Controlled Trial.

Chlebowski RT, Anderson GL, Manson JE, Prentice RL, Aragaki AK, Snetselaar L, Beresford SAA, Kuller LH, Johnson K, Lane D, Luo J, Rohan TE, Jiao L, Barac A, Womack C, Coday M, Datta M, Thomson CA.

JNCI Cancer Spectr. 2019 Jan 7;2(4):pky065. doi: 10.1093/jncics/pky065. eCollection 2018 Oct.

11.

Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis.

Santamaria S, Yamamoto K, Teraz-Orosz A, Koch C, Apte SS, de Groot R, Lane DA, Ahnström J.

Sci Rep. 2019 Jul 29;9(1):10914. doi: 10.1038/s41598-019-47494-w.

12.

Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function.

Crawley JTB, Zalli A, Monkman JH, Petri A, Lane DA, Ahnstrom J, Salles-Crawley II.

J Thromb Haemost. 2019 Jul 27. doi: 10.1111/jth.14593. [Epub ahead of print]

PMID:
31351019
13.

Chronic adolescent exposure to ∆9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice.

Pickel VM, Bourie F, Chan J, Mackie K, Lane DA, Wang G.

Neuropsychopharmacology. 2019 Jul 19. doi: 10.1038/s41386-019-0466-9. [Epub ahead of print]

PMID:
31323660
14.

Intratumour heterogeneity of p53 expression; causes and consequences.

Xue Y, San Luis B, Lane DP.

J Pathol. 2019 Jul 19. doi: 10.1002/path.5328. [Epub ahead of print] Review.

PMID:
31322742
15.

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles.

Yuen TY, Brown CJ, Xue Y, Tan YS, Ferrer Gago FJ, Lee XE, Neo JY, Thean D, Kaan HYK, Partridge AW, Verma CS, Lane DP, Johannes CW.

Chem Sci. 2019 May 30;10(26):6457-6466. doi: 10.1039/c9sc01456j. eCollection 2019 Jul 14.

16.

Patients' Perceptions of Atrial Fibrillation, Stroke Risk, and Oral Anticoagulation Treatment: An International Survey.

Lane DA, Meyerhoff J, Rohner U, Lip GYH.

TH Open. 2018 Jul 5;2(3):e233-e241. doi: 10.1055/s-0038-1666803. eCollection 2018 Jul.

17.

Educational Impact on Apixaban Adherence in Atrial Fibrillation (the AEGEAN STUDY): A Randomized Clinical Trial.

Montalescot G, Brotons C, Cosyns B, Crijns HJ, D'Angelo A, Drouet L, Eberli F, Lane DA, Besse B, Chan A, Vicaut E, Darius H; AEGEAN Study Investigators.

Am J Cardiovasc Drugs. 2019 Jun 26. doi: 10.1007/s40256-019-00356-2. [Epub ahead of print]

PMID:
31243691
18.

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties.

Partridge AW, Kaan HYK, Juang YC, Sadruddin A, Lim S, Brown CJ, Ng S, Thean D, Ferrer F, Johannes C, Yuen TY, Kannan S, Aronica P, Tan YS, Pradhan MR, Verma CS, Hochman J, Chen S, Wan H, Ha S, Sherborne B, Lane DP, Sawyer TK.

Molecules. 2019 Jun 20;24(12). pii: E2292. doi: 10.3390/molecules24122292.

19.

p53: updates on mechanisms, biology and therapy (I).

Lane DP, Verma CS.

J Mol Cell Biol. 2019 Mar 1;11(3):185-186. doi: 10.1093/jmcb/mjz017. No abstract available.

PMID:
31222355
20.

p53: updates on mechanisms, biology and therapy (II).

Lane DP, Verma CS.

J Mol Cell Biol. 2019 Apr 1;11(4):265-266. doi: 10.1093/jmcb/mjz018. No abstract available.

PMID:
31222348
21.

Assessing Severity of Illness in Patients Transported to Hospital by Paramedics: External Validation of 3 Prognostic Scores.

Lane DJ, Wunsch H, Saskin R, Cheskes S, Lin S, Morrison LJ, Scales DC.

Prehosp Emerg Care. 2019 Jul 15:1-9. doi: 10.1080/10903127.2019.1632998. [Epub ahead of print]

PMID:
31210571
22.

Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens.

Scarff JM, Waidyarachchi SL, Meyer CJ, Lane DJ, Chai W, Lemmon MM, Liu J, Butler MM, Bowlin TL, Lee RE, Panchal RG.

J Antibiot (Tokyo). 2019 Sep;72(9):693-701. doi: 10.1038/s41429-019-0194-8. Epub 2019 Jun 4.

PMID:
31164713
23.

Classification versus Prediction of Mortality Risk using the SIRS and qSOFA Scores in Patients with Infection Transported by Paramedics.

Lane DJ, Lin S, Scales DC.

Prehosp Emerg Care. 2019 Jun 19:1-8. doi: 10.1080/10903127.2019.1624901. [Epub ahead of print]

PMID:
31140890
24.

Characterization of Hydration Properties in Structural Ensembles of Biomolecules.

Pradhan MR, Nguyen MN, Kannan S, Fox SJ, Kwoh CK, Lane DP, Verma CS.

J Chem Inf Model. 2019 Jul 22;59(7):3316-3329. doi: 10.1021/acs.jcim.8b00453. Epub 2019 Jun 17.

PMID:
31140800
25.

Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of Both Normal and Tumor Tissues In Vivo.

Xue Y, Barker N, Hoon S, He P, Thakur T, Abdeen SR, Maruthappan P, Ghadessy FJ, Lane DP.

Cancer Res. 2019 Jul 15;79(14):3595-3607. doi: 10.1158/0008-5472.CAN-18-3744. Epub 2019 May 28.

PMID:
31138526
26.

Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly.

Frosi Y, Usher R, Lian DTG, Lane DP, Brown CJ.

BMC Biol. 2019 May 22;17(1):40. doi: 10.1186/s12915-019-0658-0.

27.

Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

Højen AA, Søgaard M, Melgaard L, Lane DA, Sørensen EE, Goldhaber SZ, Larsen TB.

BMJ Open. 2019 May 14;9(5):e026159. doi: 10.1136/bmjopen-2018-026159.

28.

Strategy to Identify Paramedic Transported Sepsis Cases in an Emergency Department Administrative Database.

Lane DJ, Blanchard IE, Cheskes S, Lazarenko G, Lin S, Morrison LJ, Saskin R, Seymour CW, Wunsch H, Scales DC.

Prehosp Emerg Care. 2019 May 31:1-9. doi: 10.1080/10903127.2019.1611978. [Epub ahead of print]

PMID:
31046502
29.

Objective measures of non-adherence in cardiometabolic diseases: a review focused on urine biochemical screening.

Lane D, Patel P, Khunti K, Gupta P.

Patient Prefer Adherence. 2019 Apr 12;13:537-547. doi: 10.2147/PPA.S162215. eCollection 2019. Review.

30.

Anticoagulation for Atrial Fibrillation in Older Adults-Using Big Data for Big Questions.

Quinn TJ, Lane DA.

Thromb Haemost. 2019 Jun;119(6):855-857. doi: 10.1055/s-0039-1688482. Epub 2019 Apr 30. No abstract available.

PMID:
31041792
31.

Stroke Prevention, Evaluation of Bleeding Risk, and Anticoagulant Treatment Management in Atrial Fibrillation Contemporary International Guidelines.

Proietti M, Lane DA, Boriani G, Lip GYH.

Can J Cardiol. 2019 May;35(5):619-633. doi: 10.1016/j.cjca.2019.02.009. Epub 2019 Feb 21. Review.

PMID:
31030864
32.

Guardian of Genome Editing.

Ho T, Lane DP.

CRISPR J. 2018 Aug;1:258-260. doi: 10.1089/crispr.2018.29021.dal. No abstract available.

PMID:
31021215
33.

Imaging features of triple-negative breast cancers according to androgen receptor status.

Candelaria RP, Adrada BE, Wei W, Thompson AM, Santiago L, Lane DL, Huang ML, Arribas EM, Rauch GM, Symmans WF, Gilcrease MZ, Huo L, Lim B, Ueno NT, Moulder SL, Yang WT.

Eur J Radiol. 2019 May;114:167-174. doi: 10.1016/j.ejrad.2019.03.017. Epub 2019 Mar 21.

PMID:
31005169
34.

Mobile Health (mHealth) technology for improved screening, patient involvement and optimising integrated care in atrial fibrillation: The mAFA (mAF-App) II randomised trial.

Guo Y, Lane DA, Wang L, Chen Y, Lip GYH; mAF-App II Trial investigators.

Int J Clin Pract. 2019 Jul;73(7):e13352. doi: 10.1111/ijcp.13352. Epub 2019 Jun 3.

PMID:
31002434
35.

Diet and mitochondrial DNA haplotype of a sperm whale (Physeter macrocephalus) found dead off Jurong Island, Singapore.

Chua MAH, Lane DJW, Ooi SK, Tay SHX, Kubodera T.

PeerJ. 2019 Apr 5;7:e6705. doi: 10.7717/peerj.6705. eCollection 2019.

36.

Understanding p53 functions through p53 antibodies.

Sabapathy K, Lane DP.

J Mol Cell Biol. 2019 Apr 1;11(4):317-329. doi: 10.1093/jmcb/mjz010.

37.

The Liverpool Centre for Cardiovascular Science.

Lip GYH, Lane DA.

Eur Heart J. 2019 Mar 21;40(12):957-958. doi: 10.1093/eurheartj/ehz107. No abstract available.

PMID:
30896770
38.

Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides.

Pal A, Neo K, Rajamani L, Ferrer FJ, Lane DP, Verma CS, Mortellaro A.

Sci Rep. 2019 Mar 20;9(1):4913. doi: 10.1038/s41598-019-41211-3.

39.

Biochemical Urine Testing of Adherence to Cardiovascular Medications Reveals High Rates of Nonadherence in People Attending Their Annual Review for Type 2 Diabetes.

Patel P, Gupta P, Burns A, Mohamed AA, Cole R, Lane D, Seidu S, Khunti K.

Diabetes Care. 2019 Jun;42(6):1132-1135. doi: 10.2337/dc18-1453. Epub 2019 Mar 18.

PMID:
30885952
40.

Management of asymptomatic arrhythmias: a European Heart Rhythm Association (EHRA) consensus document, endorsed by the Heart Failure Association (HFA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin America Heart Rhythm Society (LAHRS).

Arnar DO, Mairesse GH, Boriani G, Calkins H, Chin A, Coats A, Deharo JC, Svendsen JH, Heidbüchel H, Isa R, Kalman JM, Lane DA, Louw R, Lip GYH, Maury P, Potpara T, Sacher F, Sanders P, Varma N, Fauchier L; ESC Scientific Document Group ; EHRA Scientific Documents Committee .

Europace. 2019 Mar 18. pii: euz046. doi: 10.1093/europace/euz046. [Epub ahead of print]

PMID:
30882141
41.

Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein.

Lama D, Liberatore AM, Frosi Y, Nakhle J, Tsomaia N, Bashir T, Lane DP, Brown CJ, Verma CS, Auvin S.

Chem Sci. 2019 Jan 7;10(8):2489-2500. doi: 10.1039/c8sc03759k. eCollection 2019 Feb 28.

42.

Antithrombotic treatment in patients with atrial fibrillation and acute coronary syndromes: results of the European Heart Rhythm Association survey.

Lane DA, Dagres N, Dan GA, García Seara J, Iliodromitis K, Lenarczyk R, Lip GYH, Mansourati J, Marín F, Scherr D, Potpara TS.

Europace. 2019 Jul 1;21(7):1116-1125. doi: 10.1093/europace/euz033.

PMID:
30874724
43.

SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment.

Abdel-Fatah TMA, Broom RJ, Lu J, Moseley PM, Huang B, Li L, Liu S, Chen L, Ma RZ, Cao W, Wang X, Li Y, Perry JK, Aleskandarany M, Nolan CC, Rakha EA, Lobie PE, Chan SYT, Ellis IO, Hwang LA, Lane DP, Green AR, Liu DX.

Br J Cancer. 2019 Apr;120(7):728-745. doi: 10.1038/s41416-019-0405-x. Epub 2019 Feb 28.

PMID:
30816325
44.

Is There a Spillover Effect of Targeted Dietary Change on Untargeted Health Behaviors? Evidence From a Dietary Modification Trial.

Sarma EA, Moyer A, Messina CR, Laroche HH, Snetselaar L, Van Horn L, Lane DS.

Health Educ Behav. 2019 Aug;46(4):569-581. doi: 10.1177/1090198119831756. Epub 2019 Feb 27.

PMID:
30808245
45.

The Emerging Identity of the Preventive Medicine Specialty: A Model for the Population Health Transition.

Jadotte YT, Leisy HB, Noel K, Lane DS.

Am J Prev Med. 2019 Apr;56(4):614-621. doi: 10.1016/j.amepre.2018.10.031. Epub 2019 Feb 16. No abstract available.

PMID:
30782402
46.

Atrial Fibrillation and Cognitive Function: JACC Review Topic of the Week.

Diener HC, Hart RG, Koudstaal PJ, Lane DA, Lip GYH.

J Am Coll Cardiol. 2019 Feb 12;73(5):612-619. doi: 10.1016/j.jacc.2018.10.077. Review.

PMID:
30732716
47.

Improving the Prescription of Oral Anticoagulants in Atrial Fibrillation: A Systematic Review.

Pritchett RV, Bem D, Turner GM, Thomas GN, Clarke JL, Fellows R, Lane DA, Jolly K.

Thromb Haemost. 2019 Feb;119(2):294-307. doi: 10.1055/s-0038-1676835. Epub 2019 Jan 22.

PMID:
30669165
48.

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.

Newnham M, South K, Bleda M, Auger WR, Barberà JA, Bogaard H, Bunclark K, Cannon JE, Delcroix M, Hadinnapola C, Howard LS, Jenkins D, Mayer E, Ng C, Rhodes CJ, Screaton N, Sheares K, Simpson MA, Southwood M, Su L, Taboada D, Traylor M, Trembath RC, Villar SS, Wilkins MR, Wharton J, Gräf S, Pepke-Zaba J, Laffan M, Lane DA, Morrell NW, Toshner M.

Eur Respir J. 2019 Mar 28;53(3). pii: 1801805. doi: 10.1183/13993003.01805-2018. Print 2019 Mar.

49.

Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket.

Pradhan MR, Siau JW, Kannan S, Nguyen MN, Ouaray Z, Kwoh CK, Lane DP, Ghadessy F, Verma CS.

Nucleic Acids Res. 2019 Feb 28;47(4):1637-1652. doi: 10.1093/nar/gky1314.

50.

Association Between Early Intravenous Fluids Provided by Paramedics and Subsequent In-Hospital Mortality Among Patients With Sepsis.

Lane DJ, Wunsch H, Saskin R, Cheskes S, Lin S, Morrison LJ, Scales DC.

JAMA Netw Open. 2018 Dec 7;1(8):e185845. doi: 10.1001/jamanetworkopen.2018.5845. Erratum in: JAMA Netw Open. 2019 Jan 4;2(1):e187976.

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