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Aminomethyl spectinomycins: a novel antibacterial chemotype for biothreat pathogens.

Scarff JM, Waidyarachchi SL, Meyer CJ, Lane DJ, Chai W, Lemmon MM, Liu J, Butler MM, Bowlin TL, Lee RE, Panchal RG.

J Antibiot (Tokyo). 2019 Jun 4. doi: 10.1038/s41429-019-0194-8. [Epub ahead of print]


Classification versus prediction of mortality risk using the SIRS and qSOFA scores in patients with infection transported by paramedics.

Lane DJ, Lin S, Scales DC.

Prehosp Emerg Care. 2019 May 29:1-9. doi: 10.1080/10903127.2019.1624901. [Epub ahead of print]


Characterization of hydration properties in structural ensemble of biomolecules.

Pradhan M, Nguyen MN, Kannan S, Fox SJ, Kwoh CK, Lane DP, Verma CS.

J Chem Inf Model. 2019 May 29. doi: 10.1021/acs.jcim.8b00453. [Epub ahead of print]


Bortezomib Stabilizes and Activates p53 in Proliferative Compartments of both Normal and Tumor Tissues In Vivo.

Xue Y, Barker N, Hoon S, He P, Thakur T, Abdeen SR, Maruthappan P, Ghadessy FJ, Lane DP.

Cancer Res. 2019 May 28. pii: canres.3744.2018. doi: 10.1158/0008-5472.CAN-18-3744. [Epub ahead of print]


Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly.

Frosi Y, Usher R, Lian DTG, Lane DP, Brown CJ.

BMC Biol. 2019 May 22;17(1):40. doi: 10.1186/s12915-019-0658-0.


Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

Højen AA, Søgaard M, Melgaard L, Lane DA, Sørensen EE, Goldhaber SZ, Larsen TB.

BMJ Open. 2019 May 14;9(5):e026159. doi: 10.1136/bmjopen-2018-026159.


Strategy to Identify Paramedic Transported Sepsis Cases in an Emergency Department Administrative Database.

Lane DJ, Blanchard IE, Cheskes S, Lazarenko G, Lin S, Morrison LJ, Saskin R, Seymour CW, Wunsch H, Scales DC.

Prehosp Emerg Care. 2019 May 31:1-9. doi: 10.1080/10903127.2019.1611978. [Epub ahead of print]


Objective measures of non-adherence in cardiometabolic diseases: a review focused on urine biochemical screening.

Lane D, Patel P, Khunti K, Gupta P.

Patient Prefer Adherence. 2019 Apr 12;13:537-547. doi: 10.2147/PPA.S162215. eCollection 2019. Review.


Anticoagulation for Atrial Fibrillation in Older Adults-Using Big Data for Big Questions.

Quinn TJ, Lane DA.

Thromb Haemost. 2019 Jun;119(6):855-857. doi: 10.1055/s-0039-1688482. Epub 2019 Apr 30. No abstract available.


Stroke Prevention, Evaluation of Bleeding Risk, and Anticoagulant Treatment Management in Atrial Fibrillation Contemporary International Guidelines.

Proietti M, Lane DA, Boriani G, Lip GYH.

Can J Cardiol. 2019 May;35(5):619-633. doi: 10.1016/j.cjca.2019.02.009. Epub 2019 Feb 21. Review.


Guardian of Genome Editing.

Ho T, Lane DP.

CRISPR J. 2018 Aug;1:258-260. doi: 10.1089/crispr.2018.29021.dal. No abstract available.


Imaging features of triple-negative breast cancers according to androgen receptor status.

Candelaria RP, Adrada BE, Wei W, Thompson AM, Santiago L, Lane DL, Huang ML, Arribas EM, Rauch GM, Symmans WF, Gilcrease MZ, Huo L, Lim B, Ueno NT, Moulder SL, Yang WT.

Eur J Radiol. 2019 May;114:167-174. doi: 10.1016/j.ejrad.2019.03.017. Epub 2019 Mar 21.


Mobile Health (mHealth) technology for improved screening, patient involvement and optimising integrated care in atrial fibrillation: The mAFA (mAF-App) II randomised trial.

Guo Y, Lane DA, Wang L, Chen Y, Lip GYH; mAF-App II Trial investigators.

Int J Clin Pract. 2019 Apr 19:e13352. doi: 10.1111/ijcp.13352. [Epub ahead of print]


Diet and mitochondrial DNA haplotype of a sperm whale (Physeter macrocephalus) found dead off Jurong Island, Singapore.

Chua MAH, Lane DJW, Ooi SK, Tay SHX, Kubodera T.

PeerJ. 2019 Apr 5;7:e6705. doi: 10.7717/peerj.6705. eCollection 2019.


Understanding p53 functions through p53 antibodies.

Sabapathy K, Lane DP.

J Mol Cell Biol. 2019 Feb 14. pii: mjz010. doi: 10.1093/jmcb/mjz010. [Epub ahead of print]


The Liverpool Centre for Cardiovascular Science.

Lip GYH, Lane DA.

Eur Heart J. 2019 Mar 21;40(12):957-958. doi: 10.1093/eurheartj/ehz107. No abstract available.


Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides.

Pal A, Neo K, Rajamani L, Ferrer FJ, Lane DP, Verma CS, Mortellaro A.

Sci Rep. 2019 Mar 20;9(1):4913. doi: 10.1038/s41598-019-41211-3.


Biochemical Urine Testing of Adherence to Cardiovascular Medications Reveals High Rates of Nonadherence in People Attending Their Annual Review for Type 2 Diabetes.

Patel P, Gupta P, Burns A, Mohamed AA, Cole R, Lane D, Seidu S, Khunti K.

Diabetes Care. 2019 Jun;42(6):1132-1135. doi: 10.2337/dc18-1453. Epub 2019 Mar 18.


Management of asymptomatic arrhythmias: a European Heart Rhythm Association (EHRA) consensus document, endorsed by the Heart Failure Association (HFA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin America Heart Rhythm Society (LAHRS).

Arnar DO, Mairesse GH, Boriani G, Calkins H, Chin A, Coats A, Deharo JC, Svendsen JH, Heidbüchel H, Isa R, Kalman JM, Lane DA, Louw R, Lip GYH, Maury P, Potpara T, Sacher F, Sanders P, Varma N, Fauchier L; ESC Scientific Document Group ; EHRA Scientific Documents Committee .

Europace. 2019 Mar 18. pii: euz046. doi: 10.1093/europace/euz046. [Epub ahead of print]


Structural insights reveal a recognition feature for tailoring hydrocarbon stapled-peptides against the eukaryotic translation initiation factor 4E protein.

Lama D, Liberatore AM, Frosi Y, Nakhle J, Tsomaia N, Bashir T, Lane DP, Brown CJ, Verma CS, Auvin S.

Chem Sci. 2019 Jan 7;10(8):2489-2500. doi: 10.1039/c8sc03759k. eCollection 2019 Feb 28.


Antithrombotic treatment in patients with atrial fibrillation and acute coronary syndromes: results of the European Heart Rhythm Association survey.

Lane DA, Dagres N, Dan GA, García Seara J, Iliodromitis K, Lenarczyk R, Lip GYH, Mansourati J, Marín F, Scherr D, Potpara TS.

Europace. 2019 Mar 14. pii: euz033. doi: 10.1093/europace/euz033. [Epub ahead of print]


SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment.

Abdel-Fatah TMA, Broom RJ, Lu J, Moseley PM, Huang B, Li L, Liu S, Chen L, Ma RZ, Cao W, Wang X, Li Y, Perry JK, Aleskandarany M, Nolan CC, Rakha EA, Lobie PE, Chan SYT, Ellis IO, Hwang LA, Lane DP, Green AR, Liu DX.

Br J Cancer. 2019 Apr;120(7):728-745. doi: 10.1038/s41416-019-0405-x. Epub 2019 Feb 28.


Is There a Spillover Effect of Targeted Dietary Change on Untargeted Health Behaviors? Evidence From a Dietary Modification Trial.

Sarma EA, Moyer A, Messina CR, Laroche HH, Snetselaar L, Van Horn L, Lane DS.

Health Educ Behav. 2019 Feb 27:1090198119831756. doi: 10.1177/1090198119831756. [Epub ahead of print]


The Emerging Identity of the Preventive Medicine Specialty: A Model for the Population Health Transition.

Jadotte YT, Leisy HB, Noel K, Lane DS.

Am J Prev Med. 2019 Apr;56(4):614-621. doi: 10.1016/j.amepre.2018.10.031. Epub 2019 Feb 16. No abstract available.


Atrial Fibrillation and Cognitive Function: JACC Review Topic of the Week.

Diener HC, Hart RG, Koudstaal PJ, Lane DA, Lip GYH.

J Am Coll Cardiol. 2019 Feb 12;73(5):612-619. doi: 10.1016/j.jacc.2018.10.077. Review.


Improving the Prescription of Oral Anticoagulants in Atrial Fibrillation: A Systematic Review.

Pritchett RV, Bem D, Turner GM, Thomas GN, Clarke JL, Fellows R, Lane DA, Jolly K.

Thromb Haemost. 2019 Feb;119(2):294-307. doi: 10.1055/s-0038-1676835. Epub 2019 Jan 22.


The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.

Newnham M, South K, Bleda M, Auger WR, Barberà JA, Bogaard H, Bunclark K, Cannon JE, Delcroix M, Hadinnapola C, Howard LS, Jenkins D, Mayer E, Ng C, Rhodes CJ, Screaton N, Sheares K, Simpson MA, Southwood M, Su L, Taboada D, Traylor M, Trembath RC, Villar SS, Wilkins MR, Wharton J, Gräf S, Pepke-Zaba J, Laffan M, Lane DA, Morrell NW, Toshner M.

Eur Respir J. 2019 Mar 28;53(3). pii: 1801805. doi: 10.1183/13993003.01805-2018. Print 2019 Mar.


Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket.

Pradhan MR, Siau JW, Kannan S, Nguyen MN, Ouaray Z, Kwoh CK, Lane DP, Ghadessy F, Verma CS.

Nucleic Acids Res. 2019 Feb 28;47(4):1637-1652. doi: 10.1093/nar/gky1314.


Association Between Early Intravenous Fluids Provided by Paramedics and Subsequent In-Hospital Mortality Among Patients With Sepsis.

Lane DJ, Wunsch H, Saskin R, Cheskes S, Lin S, Morrison LJ, Scales DC.

JAMA Netw Open. 2018 Dec 7;1(8):e185845. doi: 10.1001/jamanetworkopen.2018.5845. Erratum in: JAMA Netw Open. 2019 Jan 4;2(1):e187976.


Radiation-induced astrocyte senescence is rescued by Δ133p53.

Turnquist C, Beck JA, Horikawa I, Obiorah IE, Von Muhlinen N, Vojtesek B, Lane DP, Grunseich C, Chahine JJ, Ames HM, Smart DD, Harris BT, Harris CC.

Neuro Oncol. 2019 Mar 18;21(4):474-485. doi: 10.1093/neuonc/noz001.


Persistent vasomotor symptoms and breast cancer in the Women's Health Initiative.

Chlebowski RT, Mortimer JE, Crandall CJ, Pan K, Manson JE, Nelson R, Johnson KC, Vitolin MZ, Lane D, Wactawski-Wende J, Kwan K, Stefanick ML.

Menopause. 2018 Dec 28;26(6):578-587. doi: 10.1097/GME.0000000000001283.


Assessing the potential of quantitative 2D HSQC NMR in 13C enriched living organisms.

Lane D, Skinner TE, Gershenzon NI, Bermel W, Soong R, Dutta Majumdar R, Liaghati Mobarhan Y, Schmidt S, Heumann H, Monette M, Simpson MJ, Simpson AJ.

J Biomol NMR. 2019 Feb;73(1-2):31-42. doi: 10.1007/s10858-018-0221-2. Epub 2019 Jan 2.


Electronic patient identification for sample labeling reduces wrong blood in tube errors.

Kaufman RM, Dinh A, Cohn CS, Fung MK, Gorlin J, Melanson S, Murphy MF, Ziman A, Elahie AL, Chasse D, Degree L, Dunbar NM, Dzik WH, Flanagan P, Gabert K, Ipe TS, Jackson B, Lane D, Raspollini E, Ray C, Sharon Y, Ellis M, Selleng K, Staves J, Yu P, Zeller M, Yazer M; BEST Collaborative.

Transfusion. 2019 Mar;59(3):972-980. doi: 10.1111/trf.15102. Epub 2018 Dec 14.


Association of Body Fat and Risk of Breast Cancer in Postmenopausal Women With Normal Body Mass Index: A Secondary Analysis of a Randomized Clinical Trial and Observational Study.

Iyengar NM, Arthur R, Manson JE, Chlebowski RT, Kroenke CH, Peterson L, Cheng TD, Feliciano EC, Lane D, Luo J, Nassir R, Pan K, Wassertheil-Smoller S, Kamensky V, Rohan TE, Dannenberg AJ.

JAMA Oncol. 2018 Dec 6. doi: 10.1001/jamaoncol.2018.5327. [Epub ahead of print]


Improvements in lipid suppression for 1 H NMR-based metabolomics: Applications to solution-state and HR-MAS NMR in natural and in vivo samples.

Hassan Q, Dutta Majumdar R, Wu B, Lane D, Tabatabaei-Anraki M, Soong R, Simpson MJ, Simpson AJ.

Magn Reson Chem. 2018 Dec 5. doi: 10.1002/mrc.4814. [Epub ahead of print]


Cardiovascular Medication Stability in Urine for Non-Adherence Screening by LC-MS-MS.

Burns AD, Lane D, Cole R, Patel P, Gupta P.

J Anal Toxicol. 2019 May 1;43(4):325-329. doi: 10.1093/jat/bky090.


Association Between Intake of Red and Processed Meat and Survival in Patients With Colorectal Cancer in a Pooled Analysis.

Carr PR, Banbury B, Berndt SI, Campbell PT, Chang-Claude J, Hayes RB, Howard BV, Jansen L, Jacobs E, Lane DS, Nishihara R, Ogino S, Phipps AI, Slattery ML, Stefanick ML, Wallace R, Walter V, White E, Wu K, Peters U, Chan AT, Newcomb PA, Brenner H, Hoffmeister M.

Clin Gastroenterol Hepatol. 2018 Nov 23. pii: S1542-3565(18)31279-5. doi: 10.1016/j.cgh.2018.11.036. [Epub ahead of print]


Dried bonito dashi: Contributions of mineral salts and organic acids to the taste of dashi.

Delay ER, Weaver B, Lane DR, Kondoh T.

Physiol Behav. 2019 Feb 1;199:127-136. doi: 10.1016/j.physbeh.2018.11.016. Epub 2018 Nov 14.


Support for evidence-based alcohol policy in Ireland: results from the Community Action on Alcohol Pilot Project.

Davoren MP, Lane D, Kirby J, Gibney K, Kinsley G, Hope A, Byrne M, Perry IJ.

J Public Health Policy. 2019 Mar;40(1):76-90. doi: 10.1057/s41271-018-0151-y.


Initiation of Triple Therapy with Multiple Inhalers in Chronic Obstructive Pulmonary Disease: An Analysis of Treatment Patterns from a U.S. Retrospective Database Study.

Lane DC, Stemkowski S, Stanford RH, Tao Z.

J Manag Care Spec Pharm. 2018 Nov;24(11):1165-1172. doi: 10.18553/jmcp.2018.24.11.1165.


Selective interactions between diverse STEs organize the ANT-C Hox cluster.

Li M, Ma Z, Roy S, Patel SK, Lane DC, Duffy CR, Cai HN.

Sci Rep. 2018 Oct 11;8(1):15158. doi: 10.1038/s41598-018-33588-4.


Urban coral reefs: Degradation and resilience of hard coral assemblages in coastal cities of East and Southeast Asia.

Heery EC, Hoeksema BW, Browne NK, Reimer JD, Ang PO, Huang D, Friess DA, Chou LM, Loke LHL, Saksena-Taylor P, Alsagoff N, Yeemin T, Sutthacheep M, Vo ST, Bos AR, Gumanao GS, Syed Hussein MA, Waheed Z, Lane DJW, Johan O, Kunzmann A, Jompa J, Suharsono, Taira D, Bauman AG, Todd PA.

Mar Pollut Bull. 2018 Oct;135:654-681. doi: 10.1016/j.marpolbul.2018.07.041. Epub 2018 Aug 1. Review.


Weight loss and breast cancer incidence in postmenopausal women.

Chlebowski RT, Luo J, Anderson GL, Barrington W, Reding K, Simon MS, Manson JE, Rohan TE, Wactawski-Wende J, Lane D, Strickler H, Mosaver-Rahmani Y, Freudenheim JL, Saquib N, Stefanick ML.

Cancer. 2019 Jan 15;125(2):205-212. doi: 10.1002/cncr.31687. Epub 2018 Oct 8.


Effectiveness of Cognitive Behavioral Therapy for Depression and Anxiety in Patients With Cardiovascular Disease: A Systematic Review and Meta-Analysis.

Reavell J, Hopkinson M, Clarkesmith D, Lane DA.

Psychosom Med. 2018 Oct;80(8):742-753. doi: 10.1097/PSY.0000000000000626.


Synthetic 10FN3-based mono- and bivalent inhibitors of MDM2/X function.

Lau SY, Siau JW, Sobota RM, Wang CI, Zhong P, Lane DP, Ghadessy FJ.

Protein Eng Des Sel. 2018 Jul 1;31(7-8):301-312. doi: 10.1093/protein/gzy018.


Improved Outcomes by Integrated Care of Anticoagulated Patients with Atrial Fibrillation Using the Simple ABC (Atrial Fibrillation Better Care) Pathway.

Proietti M, Romiti GF, Olshansky B, Lane DA, Lip GYH.

Am J Med. 2018 Nov;131(11):1359-1366.e6. doi: 10.1016/j.amjmed.2018.06.012. Epub 2018 Aug 26.


Enhanced activity of an ADAMTS-13 variant (R568K/F592Y/R660K/Y661F/Y665F) against platelet agglutination in vitro and in a murine model of acute ischemic stroke.

South K, Denorme F, Salles-Crawley II, De Meyer SF, Lane DA.

J Thromb Haemost. 2018 Nov;16(11):2289-2299. doi: 10.1111/jth.14275. Epub 2018 Oct 24.


Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report.

Lip GYH, Banerjee A, Boriani G, Chiang CE, Fargo R, Freedman B, Lane DA, Ruff CT, Turakhia M, Werring D, Patel S, Moores L.

Chest. 2018 Nov;154(5):1121-1201. doi: 10.1016/j.chest.2018.07.040. Epub 2018 Aug 22.


Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive.

Keszei M, Record J, Kritikou JS, Wurzer H, Geyer C, Thiemann M, Drescher P, Brauner H, Köcher L, James J, He M, Baptista MA, Dahlberg CI, Biswas A, Lain S, Lane DP, Song W, Pütsep K, Vandenberghe P, Snapper SB, Westerberg LS.

J Clin Invest. 2018 Aug 31;128(9):4115-4131. doi: 10.1172/JCI64772. Epub 2018 Aug 20.


Computational modelling for decision-making: where, why, what, who and how.

Calder M, Craig C, Culley D, de Cani R, Donnelly CA, Douglas R, Edmonds B, Gascoigne J, Gilbert N, Hargrove C, Hinds D, Lane DC, Mitchell D, Pavey G, Robertson D, Rosewell B, Sherwin S, Walport M, Wilson A.

R Soc Open Sci. 2018 Jun 20;5(6):172096. doi: 10.1098/rsos.172096. eCollection 2018 Jun. Review.

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