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Items: 1 to 50 of 70

1.

PKCζ facilitates lymphatic metastatic spread of prostate cancer cells in a mice xenograft model.

Zang G, Mu Y, Gao L, Bergh A, Landström M.

Oncogene. 2019 May;38(22):4215-4231. doi: 10.1038/s41388-019-0722-9. Epub 2019 Jan 31.

PMID:
30705401
2.

VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma.

Mallikarjuna P, Sitaram RT, Landström M, Ljungberg B.

Oncotarget. 2018 Mar 27;9(23):16297-16310. doi: 10.18632/oncotarget.24631. eCollection 2018 Mar 27.

3.

The Nile Rat (Arvicanthis niloticus) as a Superior Carbohydrate-Sensitive Model for Type 2 Diabetes Mellitus (T2DM).

Subramaniam A, Landstrom M, Luu A, Hayes KC.

Nutrients. 2018 Feb 18;10(2). pii: E235. doi: 10.3390/nu10020235. Review.

4.

Osteoblast-derived factors promote metastatic potential in human prostate cancer cells, in part via non-canonical transforming growth factor β (TGFβ) signaling.

Karlsson T, Sundar R, Widmark A, Landström M, Persson E.

Prostate. 2018 May;78(6):446-456. doi: 10.1002/pros.23489. Epub 2018 Jan 31.

PMID:
29383751
5.

TGFβ activates PI3K-AKT signaling via TRAF6.

Song J, Landström M.

Oncotarget. 2017 Nov 2;8(59):99205-99206. doi: 10.18632/oncotarget.22275. eCollection 2017 Nov 21. No abstract available.

6.

Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer.

Gudey SK, Sundar R, Heldin CH, Bergh A, Landström M.

Oncotarget. 2017 Aug 9;8(58):97703-97726. doi: 10.18632/oncotarget.20097. eCollection 2017 Nov 17.

7.

Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion.

Holst MR, Vidal-Quadras M, Larsson E, Song J, Hubert M, Blomberg J, Lundborg M, Landström M, Lundmark R.

Cell Rep. 2017 Aug 22;20(8):1893-1905. doi: 10.1016/j.celrep.2017.08.006.

8.

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α.

Hamidi A, Song J, Thakur N, Itoh S, Marcusson A, Bergh A, Heldin CH, Landström M.

Sci Signal. 2017 Jul 4;10(486). pii: eaal4186. doi: 10.1126/scisignal.aal4186.

PMID:
28676490
9.

Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence.

Bugaytsova JA, Björnham O, Chernov YA, Gideonsson P, Henriksson S, Mendez M, Sjöström R, Mahdavi J, Shevtsova A, Ilver D, Moonens K, Quintana-Hayashi MP, Moskalenko R, Aisenbrey C, Bylund G, Schmidt A, Åberg A, Brännström K, Königer V, Vikström S, Rakhimova L, Hofer A, Ögren J, Liu H, Goldman MD, Whitmire JM, Ådén J, Younson J, Kelly CG, Gilman RH, Chowdhury A, Mukhopadhyay AK, Nair GB, Papadakos KS, Martinez-Gonzalez B, Sgouras DN, Engstrand L, Unemo M, Danielsson D, Suerbaum S, Oscarson S, Morozova-Roche LA, Olofsson A, Gröbner G, Holgersson J, Esberg A, Strömberg N, Landström M, Eldridge AM, Chromy BA, Hansen LM, Solnick JV, Lindén SK, Haas R, Dubois A, Merrell DS, Schedin S, Remaut H, Arnqvist A, Berg DE, Borén T.

Cell Host Microbe. 2017 Mar 8;21(3):376-389. doi: 10.1016/j.chom.2017.02.013.

10.

Low glycemic load diets protect against metabolic syndrome and Type 2 diabetes mellitus in the male Nile rat.

Bolsinger J, Landstrom M, Pronczuk A, Auerbach A, Hayes KC.

J Nutr Biochem. 2017 Apr;42:134-148. doi: 10.1016/j.jnutbio.2017.01.007. Epub 2017 Jan 26.

11.

Transforming growth factor-β promotes aggressiveness and invasion of clear cell renal cell carcinoma.

Sitaram RT, Mallikarjuna P, Landström M, Ljungberg B.

Oncotarget. 2016 Jun 14;7(24):35917-35931. doi: 10.18632/oncotarget.9177.

12.

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.

Song J, Mu Y, Li C, Bergh A, Miaczynska M, Heldin CH, Landström M.

Oncotarget. 2016 Jan 5;7(1):279-92. doi: 10.18632/oncotarget.6346.

13.

The Role of Ubiquitination to Determine Non-Smad Signaling Responses.

Gudey SK, Landström M.

Methods Mol Biol. 2016;1344:355-63. doi: 10.1007/978-1-4939-2966-5_23.

PMID:
26520137
14.

CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.

Yakymovych I, Yakymovych M, Zang G, Mu Y, Bergh A, Landström M, Heldin CH.

J Cell Biol. 2015 Jul 20;210(2):319-32. doi: 10.1083/jcb.201411025. Epub 2015 Jul 13.

15.

TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells.

Mu Y, Zang G, Engström U, Busch C, Landström M.

Br J Cancer. 2015 Mar 31;112(7):1223-31. doi: 10.1038/bjc.2015.71.

16.

TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.

Sundar R, Gudey SK, Heldin CH, Landström M.

Cell Cycle. 2015;14(4):554-65. doi: 10.4161/15384101.2014.990302.

17.

TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1.

Thakur N, Gudey SK, Marcusson A, Fu JY, Bergh A, Heldin CH, Landström M.

Cell Cycle. 2014;13(15):2400-14. doi: 10.4161/cc.29339.

18.

Regulated intramembrane proteolysis of the TGFβ type I receptor conveys oncogenic signals.

Gudey SK, Wallenius A, Landström M.

Future Oncol. 2014 Aug;10(11):1853-61. doi: 10.2217/fon.14.45. Epub 2014 Mar 5. Review.

PMID:
24597658
19.

TRAF6 stimulates the tumor-promoting effects of TGFβ type I receptor through polyubiquitination and activation of presenilin 1.

Gudey SK, Sundar R, Mu Y, Wallenius A, Zang G, Bergh A, Heldin CH, Landström M.

Sci Signal. 2014 Jan 7;7(307):ra2. doi: 10.1126/scisignal.2004207.

PMID:
24399296
20.

APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration.

Ekman M, Mu Y, Lee SY, Edlund S, Kozakai T, Thakur N, Tran H, Qian J, Groeden J, Heldin CH, Landström M.

Mol Biol Cell. 2012 Jun;23(11):2109-21. doi: 10.1091/mbc.E10-12-1000. Epub 2012 Apr 11.

21.

Polyubiquitination of transforming growth factor β (TGFβ)-associated kinase 1 mediates nuclear factor-κB activation in response to different inflammatory stimuli.

Hamidi A, von Bulow V, Hamidi R, Winssinger N, Barluenga S, Heldin CH, Landström M.

J Biol Chem. 2012 Jan 2;287(1):123-33. doi: 10.1074/jbc.M111.285122. Epub 2011 Nov 8.

22.

Non-Smad signaling pathways.

Mu Y, Gudey SK, Landström M.

Cell Tissue Res. 2012 Jan;347(1):11-20. doi: 10.1007/s00441-011-1201-y. Epub 2011 Jun 24. Review.

PMID:
21701805
23.

TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.

Mu Y, Sundar R, Thakur N, Ekman M, Gudey SK, Yakymovych M, Hermansson A, Dimitriou H, Bengoechea-Alonso MT, Ericsson J, Heldin CH, Landström M.

Nat Commun. 2011;2:330. doi: 10.1038/ncomms1332.

24.

The TAK1-TRAF6 signalling pathway.

Landström M.

Int J Biochem Cell Biol. 2010 May;42(5):585-9. doi: 10.1016/j.biocel.2009.12.023. Epub 2010 Jan 12. Review.

PMID:
20060931
25.

Perceptions of registered and enrolled nurses on thirst in mechanically ventilated adult patients in intensive care units-a phenomenographic study.

Landström M, Rehn IM, Frisman GH.

Intensive Crit Care Nurs. 2009 Jun;25(3):133-9. doi: 10.1016/j.iccn.2009.03.001. Epub 2009 Apr 24.

PMID:
19394226
26.

TGF-beta uses the E3-ligase TRAF6 to turn on the kinase TAK1 to kill prostate cancer cells.

Thakur N, Sorrentino A, Heldin CH, Landström M.

Future Oncol. 2009 Feb;5(1):1-3. doi: 10.2217/14796694.5.1.1. Review. No abstract available.

27.

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition.

Heldin CH, Landström M, Moustakas A.

Curr Opin Cell Biol. 2009 Apr;21(2):166-76. doi: 10.1016/j.ceb.2009.01.021. Epub 2009 Feb 23. Review.

PMID:
19237272
28.

Pro-apoptotic effect of aurothiomalate in prostate cancer cells.

Trani M, Sorrentino A, Busch C, Landström M.

Cell Cycle. 2009 Jan 15;8(2):306-13. Epub 2009 Jan 10.

PMID:
19164922
29.

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner.

Sorrentino A, Thakur N, Grimsby S, Marcusson A, von Bulow V, Schuster N, Zhang S, Heldin CH, Landström M.

Nat Cell Biol. 2008 Oct;10(10):1199-207. doi: 10.1038/ncb1780. Epub 2008 Aug 31.

PMID:
18758450
30.

E-learning of infection control: it's contagious.

Bryce E, Yassi A, Maultsaid D, Gamage B, Landstrom M, LoChang J, Hon CY.

Can J Infect Control. 2008 Winter;23(4):228, 230, 232 passim.

PMID:
19351000
32.

TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner.

Zhang S, Ekman M, Thakur N, Bu S, Davoodpour P, Grimsby S, Tagami S, Heldin CH, Landström M.

Cell Cycle. 2006 Dec;5(23):2787-95. Epub 2006 Dec 1.

PMID:
17172861
33.

2-methoxyestradiol induces apoptosis in cultured human anaplastic thyroid carcinoma cells.

Roswall P, Bu S, Rubin K, Landström M, Heldin NE.

Thyroid. 2006 Feb;16(2):143-50.

PMID:
16676399
34.

Antiproliferative activity and toxicity of 2-methoxyestradiol in cervical cancer xenograft mice.

Li L, Da J, Landström M, Ulmsten U, Fu X.

Int J Gynecol Cancer. 2005 Mar-Apr;15(2):301-7.

35.

2-Methoxyestradiol-induced apoptosis in prostate cancer cells requires Smad7.

Davoodpour P, Landström M.

J Biol Chem. 2005 Apr 15;280(15):14773-9. Epub 2005 Feb 11.

36.

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis.

Edlund S, Lee SY, Grimsby S, Zhang S, Aspenström P, Heldin CH, Landström M.

Mol Cell Biol. 2005 Feb;25(4):1475-88.

37.

Effects of 2-methoxyestradiol on proliferation, apoptosis and PET-tracer uptake in human prostate cancer cell aggregates.

Davoodpour P, Bergström M, Landström M.

Nucl Med Biol. 2004 Oct;31(7):867-74.

PMID:
15464388
38.

Induction of apoptosis and G2/M arrest by 2-methoxyestradiol in human cervical cancer HeLaS3 cells.

Li L, Bu S, Bäckström T, Landström M, Ulmsten U, Fu X.

Anticancer Res. 2004 Mar-Apr;24(2B):873-80.

39.

Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.

Edlund S, Landström M, Heldin CH, Aspenström P.

J Cell Sci. 2004 Apr 1;117(Pt 9):1835-47.

40.
41.

Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells.

Bu S, Blaukat A, Fu X, Heldin NE, Landström M.

FEBS Lett. 2002 Nov 6;531(2):141-51.

42.
43.
44.

Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells.

Landström M, Heldin NE, Bu S, Hermansson A, Itoh S, ten Dijke P, Heldin CH.

Curr Biol. 2000 May 4;10(9):535-8.

45.

Phytoestrogens and prostate disease.

Adlercreutz H, Mazur W, Bartels P, Elomaa V, Watanabe S, Wähälä K, Landström M, Lundin E, Bergh A, Damber JE, Aman P, Widmark A, Johansson A, Zhang JX, Hallmans G.

J Nutr. 2000 Mar;130(3):658S-9S. Review. No abstract available.

PMID:
10702603
46.

Effects of tobacco smoke on tumor growth and radiation response of dunning R3327 prostate adenocarcinoma in rats.

Johansson S, Landström M, Bjermer L, Henriksson R.

Prostate. 2000 Mar 1;42(4):253-9.

PMID:
10679754
47.
48.

Expression of Smad proteins in human colorectal cancer.

Korchynskyi O, Landström M, Stoika R, Funa K, Heldin CH, ten Dijke P, Souchelnytskyi S.

Int J Cancer. 1999 Jul 19;82(2):197-202.

49.

Increased smad expression and activation are associated with apoptosis in normal and malignant prostate after castration.

Brodin G, ten Dijke P, Funa K, Heldin CH, Landström M.

Cancer Res. 1999 Jun 1;59(11):2731-8.

50.

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7.

Itóh S, Landström M, Hermansson A, Itoh F, Heldin CH, Heldin NE, ten Dijke P.

J Biol Chem. 1998 Oct 30;273(44):29195-201.

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