Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 113

1.

New therapeutic approaches and novel alternatives for organophosphate toxicity.

Katz FS, Pecic S, Schneider L, Zhu Z, Hastings A, Luzac M, Macdonald J, Landry DW, Stojanovic MN.

Toxicol Lett. 2018 Jul;291:1-10. doi: 10.1016/j.toxlet.2018.03.028. Epub 2018 Mar 31.

2.

Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects.

Pham TH, Defaix C, Xu X, Deng SX, Fabresse N, Alvarez JC, Landry DW, Brachman RA, Denny CA, Gardier AM.

Biol Psychiatry. 2018 Jul 1;84(1):e3-e6. doi: 10.1016/j.biopsych.2017.10.020. Epub 2017 Oct 26. No abstract available.

PMID:
29174592
3.

Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer's Disease.

Fiorito J, Vendome J, Saeed F, Staniszewski A, Zhang H, Yan S, Deng SX, Arancio O, Landry DW.

J Med Chem. 2017 Nov 9;60(21):8858-8875. doi: 10.1021/acs.jmedchem.7b00979. Epub 2017 Oct 23.

PMID:
28985058
4.

Integrated Microfluidic Aptasensor for Mass Spectrometric Detection of Vasopressin in Human Plasma Ultrafiltrate.

Yang J, Zhu J, Pei R, Oliver JA, Landry DW, Stojanovic MN, Lin Q.

Anal Methods. 2016 Jul 14;8(26):5190-5196. doi: 10.1039/C5AY02979A. Epub 2016 May 11.

5.

A novel inhibitor of active protein kinase G attenuates chronic inflammatory and osteoarthritic pain.

Sung YJ, Sofoluke N, Nkamany M, Deng S, Xie Y, Greenwood J, Farid R, Landry DW, Ambron RT.

Pain. 2017 May;158(5):822-832. doi: 10.1097/j.pain.0000000000000832.

6.

Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.

Deng C, Lipstein MR, Scotto L, Jirau Serrano XO, Mangone MA, Li S, Vendome J, Hao Y, Xu X, Deng SX, Realubit RB, Tatonetti NP, Karan C, Lentzsch S, Fruman DA, Honig B, Landry DW, O'Connor OA.

Blood. 2017 Jan 5;129(1):88-99. doi: 10.1182/blood-2016-08-731240. Epub 2016 Oct 26.

7.

Feather and faecal corticosterone concentrations predict future reproductive decisions in harlequin ducks (Histrionicus histrionicus).

Hansen WK, Bate LJ, Landry DW, Chastel O, Parenteau C, Breuner CW.

Conserv Physiol. 2016 Jun 6;4(1):cow015. doi: 10.1093/conphys/cow015. eCollection 2016.

8.

Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.

Katz FS, Pecic S, Tran TH, Trakht I, Schneider L, Zhu Z, Ton-That L, Luzac M, Zlatanic V, Damera S, Macdonald J, Landry DW, Tong L, Stojanovic MN.

Chembiochem. 2015 Oct 12;16(15):2205-2215. doi: 10.1002/cbic.201500348. Epub 2015 Sep 9.

9.

Sulfhydryl-specific PEGylation of phosphotriesterase cysteine mutants for organophosphate detoxification.

Daffu GK, Lopez P, Katz F, Vinogradov M, Zhan CG, Landry DW, Macdonald J.

Protein Eng Des Sel. 2015 Nov;28(11):501-6. doi: 10.1093/protein/gzv036. Epub 2015 Aug 4.

PMID:
26243887
10.

Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.

Ozcan L, Xu X, Deng SX, Ghorpade DS, Thomas T, Cremers S, Hubbard B, Serrano-Wu MH, Gaestel M, Landry DW, Tabas I.

Diabetes. 2015 Oct;64(10):3396-405. doi: 10.2337/db14-1945. Epub 2015 Jun 11.

11.

Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites.

Frame IJ, Deniskin R, Rinderspacher A, Katz F, Deng SX, Moir RD, Adjalley SH, Coburn-Flynn O, Fidock DA, Willis IM, Landry DW, Akabas MH.

ACS Chem Biol. 2015 Mar 20;10(3):775-83. doi: 10.1021/cb500981y. Epub 2015 Jan 30.

12.

Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists.

Danielsson J, Yim P, Rinderspacher A, Fu XW, Zhang Y, Landry DW, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2014 Aug 1;307(3):L273-82. doi: 10.1152/ajplung.00351.2013. Epub 2014 May 30.

13.

The selective vasopressin type 1a receptor agonist selepressin (FE 202158) blocks vascular leak in ovine severe sepsis*.

Maybauer MO, Maybauer DM, Enkhbaatar P, Laporte R, Wiśniewska H, Traber LD, Lin C, Fan J, Hawkins HK, Cox RA, Wiśniewski K, Schteingart CD, Landry DW, Rivière PJ, Traber DL.

Crit Care Med. 2014 Jul;42(7):e525-e533. doi: 10.1097/CCM.0000000000000300.

14.

Characterizing vasopressin and other vasoactive mediators released during resuscitation of trauma patients.

Cohn SM, DeRosa M, McCarthy J, Song J, White C, Louden C, Ehler B, Michalek J, Landry DW.

J Trauma Acute Care Surg. 2013 Oct;75(4):620-8. doi: 10.1097/TA.0b013e31829eff31.

PMID:
24064875
15.

Synthesis of quinoline derivatives: discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease.

Fiorito J, Saeed F, Zhang H, Staniszewski A, Feng Y, Francis YI, Rao S, Thakkar DM, Deng SX, Landry DW, Arancio O.

Eur J Med Chem. 2013 Feb;60:285-94. doi: 10.1016/j.ejmech.2012.12.009. Epub 2012 Dec 14.

16.

The Vocation of a Doctor.

Landry DW.

Linacre Q. 2012 Feb;79(1):14-18. doi: 10.1179/002436312803571456. Epub 2012 Feb 1.

17.

Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase.

Pecic S, Deng SX, Morisseau C, Hammock BD, Landry DW.

Bioorg Med Chem Lett. 2012 Jan 1;22(1):601-5. doi: 10.1016/j.bmcl.2011.10.074. Epub 2011 Oct 28.

18.

Label-free microfluidic characterization of temperature-dependent biomolecular interactions.

Nguyen T, Pei R, Landry DW, Stojanovic MN, Lin Q.

Biomicrofluidics. 2011 Sep;5(3):34118-341187. doi: 10.1063/1.3620417. Epub 2011 Aug 17.

19.

Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.

Vidović D, Xie Y, Rinderspacher A, Deng SX, Landry DW, Chung C, Smith DH, Tautz L, Schürer SC.

J Comput Aided Mol Des. 2011 Sep;25(9):873-83. doi: 10.1007/s10822-011-9469-2. Epub 2011 Sep 9.

PMID:
21904909
20.

Derivation of two new human embryonic stem cell lines from nonviable human embryos.

Gavrilov S, Marolt D, Douglas NC, Prosser RW, Khalid I, Sauer MV, Landry DW, Vunjak-Novakovic G, Papaioannou VE.

Stem Cells Int. 2011;2011:765378. doi: 10.4061/2011/765378. Epub 2011 May 22.

21.

The Ngal reporter mouse detects the response of the kidney to injury in real time.

Paragas N, Qiu A, Zhang Q, Samstein B, Deng SX, Schmidt-Ott KM, Viltard M, Yu W, Forster CS, Gong G, Liu Y, Kulkarni R, Mori K, Kalandadze A, Ratner AJ, Devarajan P, Landry DW, D'Agati V, Lin CS, Barasch J.

Nat Med. 2011 Feb;17(2):216-22. doi: 10.1038/nm.2290. Epub 2011 Jan 16.

22.

Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.

Vang T, Xie Y, Liu WH, Vidović D, Liu Y, Wu S, Smith DH, Rinderspacher A, Chung C, Gong G, Mustelin T, Landry DW, Rickert RC, Schürer SC, Deng SX, Tautz L.

J Med Chem. 2011 Jan 27;54(2):562-71. doi: 10.1021/jm101004d. Epub 2010 Dec 29.

23.

Increased complexity of vasopressin's vascular actions.

Landry DW, Oliver JA.

Crit Care. 2010;14(6):1011. doi: 10.1186/cc9344. Epub 2010 Dec 13. Review.

24.

Vasopressin deficiency and vasodilatory state in end-stage liver disease.

Wagener G, Kovalevskaya G, Minhaz M, Mattis F, Emond JC, Landry DW.

J Cardiothorac Vasc Anesth. 2011 Aug;25(4):665-70. doi: 10.1053/j.jvca.2010.09.018. Epub 2010 Dec 3.

25.

San Antonio Vasopressin in Shock Symposium report.

Cohn SM, Blackbourne LH, Landry DW, Proctor KG, Walley KR, Wenzel V.

Resuscitation. 2010 Nov;81(11):1473-5. doi: 10.1016/j.resuscitation.2010.06.005. Epub 2010 Jul 23.

PMID:
20655650
26.

Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.

Bao G, Clifton M, Hoette TM, Mori K, Deng SX, Qiu A, Viltard M, Williams D, Paragas N, Leete T, Kulkarni R, Li X, Lee B, Kalandadze A, Ratner AJ, Pizarro JC, Schmidt-Ott KM, Landry DW, Raymond KN, Strong RK, Barasch J.

Nat Chem Biol. 2010 Aug;6(8):602-9. doi: 10.1038/nchembio.402. Epub 2010 Jun 27.

27.

Location of the beta 4 transmembrane helices in the BK potassium channel.

Wu RS, Chudasama N, Zakharov SI, Doshi D, Motoike H, Liu G, Yao Y, Niu X, Deng SX, Landry DW, Karlin A, Marx SO.

J Neurosci. 2009 Jul 1;29(26):8321-8. doi: 10.1523/JNEUROSCI.6191-08.2009.

28.

Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-beta load in an Alzheimer's disease mouse model.

Puzzo D, Staniszewski A, Deng SX, Privitera L, Leznik E, Liu S, Zhang H, Feng Y, Palmeri A, Landry DW, Arancio O.

J Neurosci. 2009 Jun 24;29(25):8075-86. doi: 10.1523/JNEUROSCI.0864-09.2009.

29.

Discovery of potent non-urea inhibitors of soluble epoxide hydrolase.

Xie Y, Liu Y, Gong G, Smith DH, Yan F, Rinderspacher A, Feng Y, Zhu Z, Li X, Deng SX, Branden L, Vidović D, Chung C, Schürer S, Morisseau C, Hammock BD, Landry DW.

Bioorg Med Chem Lett. 2009 Apr 15;19(8):2354-9. doi: 10.1016/j.bmcl.2008.09.066. Epub 2008 Sep 20.

30.

Potent inhibitors of Huntingtin protein aggregation in a cell-based assay.

Rinderspacher A, Cremona ML, Liu Y, Deng SX, Xie Y, Gong G, Aulner N, Többen U, Myers K, Chung C, Andersen M, Vidović D, Schürer S, Brandén L, Yamamoto A, Landry DW.

Bioorg Med Chem Lett. 2009 Mar 15;19(6):1715-7. doi: 10.1016/j.bmcl.2009.01.087. Epub 2009 Jan 30.

31.

Non-viable human embryos as a source of viable cells for embryonic stem cell derivation.

Gavrilov S, Prosser RW, Khalid I, MacDonald J, Sauer MV, Landry DW, Papaioannou VE.

Reprod Biomed Online. 2009 Feb;18(2):301-8.

PMID:
19192355
32.

Alternative strategies for the derivation of human embryonic stem cell lines and the role of dead embryos.

Gavrilov S, Papaioannou VE, Landry DW.

Curr Stem Cell Res Ther. 2009 Jan;4(1):81-6. Review.

PMID:
19149633
33.

Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation.

Gong G, Xie Y, Liu Y, Rinderspacher A, Deng SX, Feng Y, Zhu Z, Tang Y, Wyler M, Aulner N, Toebben U, Smith DH, Branden L, Chung C, Schürer S, Vidović D, Landry DW.

Bioorg Med Chem Lett. 2009 Feb 15;19(4):1191-4. doi: 10.1016/j.bmcl.2008.12.086. Epub 2008 Dec 25.

PMID:
19136257
34.

Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity.

Gao D, Narasimhan DL, Macdonald J, Brim R, Ko MC, Landry DW, Woods JH, Sunahara RK, Zhan CG.

Mol Pharmacol. 2009 Feb;75(2):318-23. doi: 10.1124/mol.108.049486. Epub 2008 Nov 5.

35.

Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists.

Xie Y, Raffo A, Ichise M, Deng S, Harris PE, Landry DW.

Bioorg Med Chem Lett. 2008 Sep 15;18(18):5111-4. doi: 10.1016/j.bmcl.2008.07.129. Epub 2008 Aug 7.

36.

Locations of the beta1 transmembrane helices in the BK potassium channel.

Liu G, Zakharov SI, Yang L, Wu RS, Deng SX, Landry DW, Karlin A, Marx SO.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10727-32. doi: 10.1073/pnas.0805212105. Epub 2008 Jul 31.

37.

Vasopressin in septic shock.

Landry DW, Oliver JA.

N Engl J Med. 2008 Jun 19;358(25):2736-7; author reply 2737-8. No abstract available.

PMID:
18572443
38.

Position and role of the BK channel alpha subunit S0 helix inferred from disulfide crosslinking.

Liu G, Zakharov SI, Yang L, Deng SX, Landry DW, Karlin A, Marx SO.

J Gen Physiol. 2008 Jun;131(6):537-48. doi: 10.1085/jgp.200809968. Epub 2008 May 12.

39.

Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.

Xie Y, Liu Y, Gong G, Rinderspacher A, Deng SX, Smith DH, Toebben U, Tzilianos E, Branden L, Vidović D, Chung C, Schürer S, Tautz L, Landry DW.

Bioorg Med Chem Lett. 2008 May 1;18(9):2840-4. doi: 10.1016/j.bmcl.2008.03.079. Epub 2008 Apr 8.

40.

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.

Bellinger AM, Reiken S, Dura M, Murphy PW, Deng SX, Landry DW, Nieman D, Lehnart SE, Samaru M, LaCampagne A, Marks AR.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2198-202. doi: 10.1073/pnas.0711074105. Epub 2008 Feb 11.

41.

Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation.

Xie Y, Deng S, Thomas CJ, Liu Y, Zhang YQ, Rinderspacher A, Huang W, Gong G, Wyler M, Cayanis E, Aulner N, Többen U, Chung C, Pampou S, Southall N, Vidović D, Schürer S, Branden L, Davis RE, Staudt LM, Inglese J, Austin CP, Landry DW, Smith DH, Auld DS.

Bioorg Med Chem Lett. 2008 Jan 1;18(1):329-35. Epub 2007 Oct 30.

42.

Endogenous and exogenous vasopressin in shock.

Oliver JA, Landry DW.

Curr Opin Crit Care. 2007 Aug;13(4):376-82. Review.

PMID:
17599006
43.

Hypocellularity and absence of compaction as criteria for embryonic death.

Landry DW, Zucker HA, Sauer MV, Reznik M, Wiebe L.

Regen Med. 2006 May;1(3):367-71.

PMID:
17465791
44.

Vasopressin administration facilitates fluid removal during hemodialysis.

van der Zee S, Thompson A, Zimmerman R, Lin J, Huan Y, Braskett M, Sciacca RR, Landry DW, Oliver JA.

Kidney Int. 2007 Feb;71(4):318-24. Epub 2006 Sep 27.

45.

Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase.

Cooper ZD, Narasimhan D, Sunahara RK, Mierzejewski P, Jutkiewicz EM, Larsen NA, Wilson IA, Landry DW, Woods JH.

Mol Pharmacol. 2006 Dec;70(6):1885-91. Epub 2006 Sep 12.

PMID:
16968810
46.

Identification of small-molecule inhibitors of the Abeta-ABAD interaction.

Xie Y, Deng S, Chen Z, Yan S, Landry DW.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4657-60. Epub 2006 Jun 14.

PMID:
16781151
47.

Blood pressure instability during hemodialysis.

Landry DW, Oliver JA.

Kidney Int. 2006 May;69(10):1710-1.

48.

Vasopressin and relativity: on the matter of deficiency and sensitivity.

Landry DW, Oliver JA.

Crit Care Med. 2006 Apr;34(4):1275-7. No abstract available.

PMID:
16550091
49.

Potassium channels and septic shock.

Oliver JA, Landry DW.

Crit Care Med. 2006 Apr;34(4):1255-7. No abstract available.

PMID:
16550079
50.

Supplemental Content

Loading ...
Support Center