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Items: 14

1.

Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon.

Chang H, Pan Y, Landrette S, Ding S, Yang D, Liu L, Tian L, Chai H, Li P, Li DM, Xu T.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18507-18516. doi: 10.1073/pnas.1906354116. Epub 2019 Aug 26.

PMID:
31451639
2.

B-cell non-Hodgkin lymphoma: Selective vulnerability to PIKFYVE inhibition.

Gayle S, Landrette S, Beeharry N, Conrad C, Hernandez M, Beckett P, Ferguson SM, Xu T, Rothberg J, Lichenstein H.

Autophagy. 2017 Jun 3;13(6):1082-1083. doi: 10.1080/15548627.2017.1304871. Epub 2017 Mar 28.

3.

Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.

Gayle S, Landrette S, Beeharry N, Conrad C, Hernandez M, Beckett P, Ferguson SM, Mandelkern T, Zheng M, Xu T, Rothberg J, Lichenstein H.

Blood. 2017 Mar 30;129(13):1768-1778. doi: 10.1182/blood-2016-09-736892. Epub 2017 Jan 19.

4.

piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation.

Gayle S, Pan Y, Landrette S, Xu T.

Stem Cell Reports. 2015 May 12;4(5):926-38. doi: 10.1016/j.stemcr.2015.03.001. Epub 2015 Apr 9.

5.

Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors.

Choi J, Landrette SF, Wang T, Evans P, Bacchiocchi A, Bjornson R, Cheng E, Stiegler AL, Gathiaka S, Acevedo O, Boggon TJ, Krauthammer M, Halaban R, Xu T.

Pigment Cell Melanoma Res. 2014 Mar;27(2):253-62. doi: 10.1111/pcmr.12197. Epub 2014 Jan 6.

6.

Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma.

Ni TK, Landrette SF, Bjornson RD, Bosenberg MW, Xu T.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):E3640-9. doi: 10.1073/pnas.1314435110. Epub 2013 Sep 3.

7.

Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling.

Pulikkan JA, Madera D, Xue L, Bradley P, Landrette SF, Kuo YH, Abbas S, Zhu LJ, Valk P, Castilla LH.

Blood. 2012 Jul 26;120(4):868-79. doi: 10.1182/blood-2012-03-414649. Epub 2012 May 21.

8.

Characterization of fluorescent eye markers for mammalian transgenic studies.

Cornett JC, Landrette SF, Xu T.

PLoS One. 2011;6(12):e29486. doi: 10.1371/journal.pone.0029486. Epub 2011 Dec 28.

9.

piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.

Landrette SF, Cornett JC, Ni TK, Bosenberg MW, Xu T.

PLoS One. 2011;6(10):e26650. doi: 10.1371/journal.pone.0026650. Epub 2011 Oct 21.

10.

Somatic genetics empowers the mouse for modeling and interrogating developmental and disease processes.

Landrette SF, Xu T.

PLoS Genet. 2011 Jul;7(7):e1002110. doi: 10.1371/journal.pgen.1002110. Epub 2011 Jul 21. Review.

11.

The transcription factor PlagL2 activates Mpl transcription and signaling in hematopoietic progenitor and leukemia cells.

Landrette SF, Madera D, He F, Castilla LH.

Leukemia. 2011 Apr;25(4):655-62. doi: 10.1038/leu.2010.301. Epub 2011 Jan 25.

12.

Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia.

Kuo YH, Landrette SF, Heilman SA, Perrat PN, Garrett L, Liu PP, Le Beau MM, Kogan SC, Castilla LH.

Cancer Cell. 2006 Jan;9(1):57-68.

13.

Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11.

Landrette SF, Kuo YH, Hensen K, Barjesteh van Waalwijk van Doorn-Khosrovani S, Perrat PN, Van de Ven WJ, Delwel R, Castilla LH.

Blood. 2005 Apr 1;105(7):2900-7. Epub 2004 Dec 7.

PMID:
15585652
14.

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia.

Castilla LH, Perrat P, Martinez NJ, Landrette SF, Keys R, Oikemus S, Flanegan J, Heilman S, Garrett L, Dutra A, Anderson S, Pihan GA, Wolff L, Liu PP.

Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4924-9. Epub 2004 Mar 24.

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