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Items: 49

1.

Epigenetic EGFR gene repression confers sensitivity to therapeutic BRAFV600E blockade in colon neuroendocrine carcinomas.

Capdevila J, Arqués O, Hernandez Mora JR, Matito J, Caratu G, Mancuso FM, Landolfi S, Barriuso J, Jimenez-Fonseca P, Lopez Lopez C, Garcia-Carbonero R, Hernando J, Matos I, Paolo N, Hernández-Losa J, Esteller M, Martínez-Cardús A, Tabernero J, Vivancos A, Palmer HG.

Clin Cancer Res. 2019 Oct 31. pii: clincanres.1266.2019. doi: 10.1158/1078-0432.CCR-19-1266. [Epub ahead of print]

PMID:
31672771
2.

Targeted multiplex proteomics for molecular prescreening and biomarker discovery in metastatic colorectal cancer.

Serna G, Ruiz-Pace F, Cecchi F, Fasani R, Jimenez J, Thyparambil S, Landolfi S, Elez E, Vivancos A, Hembrough T, Tabernero J, Dienstmann R, Nuciforo P.

Sci Rep. 2019 Sep 19;9(1):13568. doi: 10.1038/s41598-019-49867-7.

3.

Brief Report: Effectiveness of Trichloroacetic Acid vs. Electrocautery Ablation for the Treatment of Anal High-Grade Squamous Intraepithelial Lesion in HIV-Infected Patients.

Burgos J, Martin-Castillo M, Landolfi S, Dinares MC, Villar J, Navarro J, Ribera E, Falcó V, Curran A.

J Acquir Immune Defic Syndr. 2018 Dec 15;79(5):612-616. doi: 10.1097/QAI.0000000000001847.

PMID:
30179983
4.

Clinicopathological and Molecular Characterization of Metastatic Gastrointestinal Stromal Tumors with Prolonged Benefit to Frontline Imatinib.

Serrano C, García-Del-Muro X, Valverde C, Sebio A, Durán J, Manzano A, Pajares I, Hindi N, Landolfi S, Jiménez L, Rubió-Casadevall J, Estival A, Lavernia J, Safont MJ, Pericay C, Díaz-Beveridge R, Martínez-Marín V, Vicente-Baz D, Vivancos A, Hernández-Losa J, Arribas J, Carles J.

Oncologist. 2019 May;24(5):680-687. doi: 10.1634/theoncologist.2018-0032. Epub 2018 Aug 20.

PMID:
30126859
5.

TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence.

Puig I, Tenbaum SP, Chicote I, Arqués O, Martínez-Quintanilla J, Cuesta-Borrás E, Ramírez L, Gonzalo P, Soto A, Aguilar S, Eguizabal C, Caratù G, Prat A, Argilés G, Landolfi S, Casanovas O, Serra V, Villanueva A, Arroyo AG, Terracciano L, Nuciforo P, Seoane J, Recio JA, Vivancos A, Dienstmann R, Tabernero J, Palmer HG.

J Clin Invest. 2018 Aug 31;128(9):3887-3905. doi: 10.1172/JCI96393. Epub 2018 Aug 6.

6.

Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer.

Bullman S, Pedamallu CS, Sicinska E, Clancy TE, Zhang X, Cai D, Neuberg D, Huang K, Guevara F, Nelson T, Chipashvili O, Hagan T, Walker M, Ramachandran A, Diosdado B, Serna G, Mulet N, Landolfi S, Ramon Y Cajal S, Fasani R, Aguirre AJ, Ng K, Élez E, Ogino S, Tabernero J, Fuchs CS, Hahn WC, Nuciforo P, Meyerson M.

Science. 2017 Dec 15;358(6369):1443-1448. doi: 10.1126/science.aal5240. Epub 2017 Nov 23.

7.

Comparison between small bowel manometric patterns and full-thickness biopsy histopathology in severe intestinal dysmotility.

Malagelada C, Karunaratne TB, Accarino A, Cogliandro RF, Landolfi S, Gori A, Boschetti E, Malagelada JR, Stanghellini V, Azpiroz F, De Giorgio R.

Neurogastroenterol Motil. 2018 Mar;30(3). doi: 10.1111/nmo.13219. Epub 2017 Sep 22.

PMID:
28941004
8.

The role of oncogenic human papillomavirus determination for diagnosis of high-grade anal intraepithelial neoplasia in HIV-infected MSM.

Burgos J, Hernández-Losa J, Landolfi S, Guelar A, Dinares M, Villar J, Navarro J, Ribera E, Falcó V, Curran A.

AIDS. 2017 Oct 23;31(16):2227-2233. doi: 10.1097/QAD.0000000000001605.

PMID:
28723712
9.

Analysis of mutant allele fractions in driver genes in colorectal cancer - biological and clinical insights.

Dienstmann R, Elez E, Argiles G, Matos I, Sanz-Garcia E, Ortiz C, Macarulla T, Capdevila J, Alsina M, Sauri T, Verdaguer H, Vilaro M, Ruiz-Pace F, Viaplana C, Garcia A, Landolfi S, Palmer HG, Nuciforo P, Rodon J, Vivancos A, Tabernero J.

Mol Oncol. 2017 Sep;11(9):1263-1272. doi: 10.1002/1878-0261.12099. Epub 2017 Jul 20.

10.

Loss of the EPH receptor B6 contributes to colorectal cancer metastasis.

Mateo-Lozano S, Bazzocco S, Rodrigues P, Mazzolini R, Andretta E, Dopeso H, Fernández Y, Del Llano E, Bilic J, Suárez-López L, Macaya I, Cartón-García F, Nieto R, Jimenez-Flores LM, de Marcondes PG, Nuñez Y, Afonso E, Cacci K, Hernández-Losa J, Landolfi S, Abasolo I, Ramón Y Cajal S, Mariadason JM, Schwartz S Jr, Matsui T, Arango D.

Sci Rep. 2017 Mar 6;7:43702. doi: 10.1038/srep43702.

11.

Risk factors of high-grade anal intraepithelial neoplasia recurrence in HIV-infected MSM.

Burgos J, Curran A, Landolfi S, Guelar A, Miguel L, Dinares M, Villar J, Navarro J, Hernandez-Losa J, Falcó V.

AIDS. 2017 Jun 1;31(9):1245-1252. doi: 10.1097/QAD.0000000000001433.

PMID:
28252530
12.

Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.

Andretta E, Cartón-García F, Martínez-Barriocanal Á, de Marcondes PG, Jimenez-Flores LM, Macaya I, Bazzocco S, Bilic J, Rodrigues P, Nieto R, Landolfi S, Ramon Y Cajal S, Schwartz S, Brown A, Dopeso H, Arango D.

Sci Rep. 2017 Feb 7;7:41576. doi: 10.1038/srep41576.

13.

Towards a new paradigm of microscopic colitis: Incomplete and variant forms.

Guagnozzi D, Landolfi S, Vicario M.

World J Gastroenterol. 2016 Oct 14;22(38):8459-8471. Review.

14.

Epigenetic Homogeneity Within Colorectal Tumors Predicts Shorter Relapse-Free and Overall Survival Times for Patients With Locoregional Cancer.

Martínez-Cardús A, Moran S, Musulen E, Moutinho C, Manzano JL, Martinez-Balibrea E, Tierno M, Élez E, Landolfi S, Lorden P, Arribas C, Müller F, Bock C, Tabernero J, Esteller M.

Gastroenterology. 2016 Nov;151(5):961-972. doi: 10.1053/j.gastro.2016.08.001. Epub 2016 Aug 10.

15.

DPYD Genotyping to Predict Adverse Events Following Treatment With Fluorouracil-Based Adjuvant Chemotherapy in Patients With Stage III Colon Cancer: A Secondary Analysis of the PETACC-8 Randomized Clinical Trial.

Boige V, Vincent M, Alexandre P, Tejpar S, Landolfi S, Le Malicot K, Greil R, Cuyle PJ, Yilmaz M, Faroux R, Matzdorff A, Salazar R, Lepage C, Taieb J, Laurent-Puig P.

JAMA Oncol. 2016 May 1;2(5):655-662. doi: 10.1001/jamaoncol.2015.5392.

PMID:
26794347
16.

The effectiveness of electrocautery ablation for the treatment of high-grade anal intraepithelial neoplasia in HIV-infected men who have sex with men.

Burgos J, Curran A, Landolfi S, Navarro J, Tallada N, Guelar A, Crespo M, Ocaña I, Ribera E, Falcó V.

HIV Med. 2016 Aug;17(7):524-31. doi: 10.1111/hiv.12352. Epub 2015 Dec 21.

17.

Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch Repair Status of the MOSAIC Study.

André T, de Gramont A, Vernerey D, Chibaudel B, Bonnetain F, Tijeras-Raballand A, Scriva A, Hickish T, Tabernero J, Van Laethem JL, Banzi M, Maartense E, Shmueli E, Carlsson GU, Scheithauer W, Papamichael D, Möehler M, Landolfi S, Demetter P, Colote S, Tournigand C, Louvet C, Duval A, Fléjou JF, de Gramont A.

J Clin Oncol. 2015 Dec 10;33(35):4176-87. doi: 10.1200/JCO.2015.63.4238. Epub 2015 Nov 2.

PMID:
26527776
18.

Right angular pregnancy at seven weeks' gestation: a case report treated by laparoscopic approach.

Capobianco G, Dessole M, Landolfi S, Fadda GM, Dessole S.

Clin Exp Obstet Gynecol. 2015;42(5):698-700.

PMID:
26524831
19.

Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer.

Arqués O, Chicote I, Puig I, Tenbaum SP, Argilés G, Dienstmann R, Fernández N, Caratù G, Matito J, Silberschmidt D, Rodon J, Landolfi S, Prat A, Espín E, Charco R, Nuciforo P, Vivancos A, Shao W, Tabernero J, Palmer HG.

Clin Cancer Res. 2016 Feb 1;22(3):644-56. doi: 10.1158/1078-0432.CCR-14-3081. Epub 2015 Jul 29.

20.

Myo5b knockout mice as a model of microvillus inclusion disease.

Cartón-García F, Overeem AW, Nieto R, Bazzocco S, Dopeso H, Macaya I, Bilic J, Landolfi S, Hernandez-Losa J, Schwartz S Jr, Ramon y Cajal S, van Ijzendoorn SC, Arango D.

Sci Rep. 2015 Jul 23;5:12312. doi: 10.1038/srep12312.

21.

Gastrointestinal endarteropathy in adult dermatomyositis.

Mestre-Torres J, Landolfi S, Selva-O'Callaghan A.

Joint Bone Spine. 2016 May;83(3):353-4. doi: 10.1016/j.jbspin.2015.03.004. Epub 2015 Jul 14. No abstract available.

PMID:
26184526
22.

Risk of progression to high-grade anal intraepithelial neoplasia in HIV-infected MSM.

Burgos J, Curran A, Tallada N, Guelar A, Navarro J, Landolfi S, Villar J, Crespo M, Ribera E, Falcó V.

AIDS. 2015 Mar 27;29(6):695-702. doi: 10.1097/QAD.0000000000000603.

PMID:
25849833
23.

RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

Rodrigues P, Macaya I, Bazzocco S, Mazzolini R, Andretta E, Dopeso H, Mateo-Lozano S, Bilić J, Cartón-García F, Nieto R, Suárez-López L, Afonso E, Landolfi S, Hernandez-Losa J, Kobayashi K, Ramón y Cajal S, Tabernero J, Tebbutt NC, Mariadason JM, Schwartz S Jr, Arango D.

Nat Commun. 2014 Nov 21;5:5458. doi: 10.1038/ncomms6458.

24.

Cyclin E amplification/overexpression is associated with poor prognosis in gastric cancer.

Alsina M, Landolfi S, Aura C, Caci K, Jimenez J, Prudkin L, Castro S, Moreno D, Navalpotro B, Tabernero J, Scaltriti M.

Ann Oncol. 2015 Feb;26(2):438-9. doi: 10.1093/annonc/mdu535. Epub 2014 Nov 17. No abstract available.

PMID:
25403579
25.

Updated guidelines for biomarker testing in colorectal carcinoma: a national consensus of the Spanish Society of Pathology and the Spanish Society of Medical Oncology.

García-Alfonso P, García-Foncillas J, Salazar R, Pérez-Segura P, García-Carbonero R, Musulén-Palet E, Cuatrecasas M, Landolfi S, Ramón Y Cajal S, Navarro S; Spanish Society of Pathology; Spanish Society of Medical Oncology.

Clin Transl Oncol. 2015 Apr;17(4):264-73. doi: 10.1007/s12094-014-1252-0. Epub 2014 Nov 6.

PMID:
25373533
26.

Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.

Pineda M, González-Acosta M, Thompson BA, Sánchez R, Gómez C, Martínez-López J, Perea J, Caldés T, Rodríguez Y, Landolfi S, Balmaña J, Lázaro C, Robles L, Capellá G, Rueda D.

Clin Genet. 2015 Jun;87(6):543-8. doi: 10.1111/cge.12467. Epub 2014 Sep 16.

PMID:
25060679
27.

Breast-conservative surgery followed by radiofrequency ablation of margins decreases the need for a second surgical procedure for close or positive margins.

Rubio IT, Landolfi S, Molla M, Cortes J, Xercavins J.

Clin Breast Cancer. 2014 Oct;14(5):346-51. doi: 10.1016/j.clbc.2014.02.002. Epub 2014 Feb 21.

PMID:
24703804
28.

A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells.

Puig I, Chicote I, Tenbaum SP, Arqués O, Herance JR, Gispert JD, Jimenez J, Landolfi S, Caci K, Allende H, Mendizabal L, Moreno D, Charco R, Espín E, Prat A, Elez ME, Argilés G, Vivancos A, Tabernero J, Rojas S, Palmer HG.

Clin Cancer Res. 2013 Dec 15;19(24):6787-801. doi: 10.1158/1078-0432.CCR-12-1740. Epub 2013 Oct 29.

29.

Level of HER2 gene amplification predicts response and overall survival in HER2-positive advanced gastric cancer treated with trastuzumab.

Gomez-Martin C, Plaza JC, Pazo-Cid R, Salud A, Pons F, Fonseca P, Leon A, Alsina M, Visa L, Rivera F, Galan MC, Del Valle E, Vilardell F, Iglesias M, Fernandez S, Landolfi S, Cuatrecasas M, Mayorga M, Jose Paulés M, Sanz-Moncasi P, Montagut C, Garralda E, Rojo F, Hidalgo M, Lopez-Rios F.

J Clin Oncol. 2013 Dec 10;31(35):4445-52. doi: 10.1200/JCO.2013.48.9070. Epub 2013 Oct 14.

PMID:
24127447
30.

SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer.

Ordóñez-Morán P, Irmisch A, Barbáchano A, Chicote I, Tenbaum S, Landolfi S, Tabernero J, Huelsken J, Muñoz A, Pálmer HG.

Oncogene. 2014 Apr 10;33(15):1975-85. doi: 10.1038/onc.2013.140. Epub 2013 Apr 29.

PMID:
23624922
31.

Brush border myosin Ia inactivation in gastric but not endometrial tumors.

Mazzolini R, Rodrigues P, Bazzocco S, Dopeso H, Ferreira AM, Mateo-Lozano S, Andretta E, Woerner SM, Alazzouzi H, Landolfi S, Hernandez-Losa J, Macaya I, Suzuki H, Ramón y Cajal S, Mooseker MS, Mariadason JM, Gebert J, Hofstra RM, Reventós J, Yamamoto H, Schwartz S Jr, Arango D.

Int J Cancer. 2013 Apr 15;132(8):1790-9. doi: 10.1002/ijc.27856. Epub 2012 Oct 20.

32.

Intestinal schistosomiasis as unusual aetiology for acute appendicitis, nowadays a rising disease in Western countries.

López de Cenarruzabeitia I, Landolfi S, Armengol Carrasco M.

Case Rep Infect Dis. 2012;2012:896820. doi: 10.1155/2012/896820. Epub 2012 Jun 26.

33.

Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.

Dienstmann R, Serpico D, Rodon J, Saura C, Macarulla T, Elez E, Alsina M, Capdevila J, Perez-Garcia J, Sánchez-Ollé G, Aura C, Prudkin L, Landolfi S, Hernández-Losa J, Vivancos A, Tabernero J.

Mol Cancer Ther. 2012 Sep;11(9):2062-71. doi: 10.1158/1535-7163.MCT-12-0290. Epub 2012 Jun 21.

34.

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer.

Tenbaum SP, Ordóñez-Morán P, Puig I, Chicote I, Arqués O, Landolfi S, Fernández Y, Herance JR, Gispert JD, Mendizabal L, Aguilar S, Ramón y Cajal S, Schwartz S Jr, Vivancos A, Espín E, Rojas S, Baselga J, Tabernero J, Muñoz A, Palmer HG.

Nat Med. 2012 Jun;18(6):892-901. doi: 10.1038/nm.2772.

PMID:
22610277
35.

Brush border myosin Ia has tumor suppressor activity in the intestine.

Mazzolini R, Dopeso H, Mateo-Lozano S, Chang W, Rodrigues P, Bazzocco S, Alazzouzi H, Landolfi S, Hernández-Losa J, Andretta E, Alhopuro P, Espín E, Armengol M, Tabernero J, Ramón y Cajal S, Kloor M, Gebert J, Mariadason JM, Schwartz S Jr, Aaltonen LA, Mooseker MS, Arango D.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1530-5. doi: 10.1073/pnas.1108411109. Epub 2012 Jan 18.

36.

[Colon metastasis of lobular breast carcinoma].

Landi F, Martí Gallostra M, Espin Basany E, Landolfi S, Armengol Carrasco M.

Cir Esp. 2012 Aug-Sep;90(7):470-1. Epub 2011 Apr 22. Spanish. No abstract available.

PMID:
21514576
37.

SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity.

Barbáchano A, Ordóñez-Morán P, García JM, Sánchez A, Pereira F, Larriba MJ, Martínez N, Hernández J, Landolfi S, Bonilla F, Pálmer HG, Rojas JM, Muñoz A.

Oncogene. 2010 Aug 26;29(34):4800-13. doi: 10.1038/onc.2010.225. Epub 2010 Jun 14.

PMID:
20543868
38.

Aprataxin tumor levels predict response of colorectal cancer patients to irinotecan-based treatment.

Dopeso H, Mateo-Lozano S, Elez E, Landolfi S, Ramos Pascual FJ, Hernández-Losa J, Mazzolini R, Rodrigues P, Bazzocco S, Carreras MJ, Espín E, Armengol M, Wilson AJ, Mariadason JM, Ramon Y Cajal S, Tabernero J, Schwartz S Jr, Arango D.

Clin Cancer Res. 2010 Apr 15;16(8):2375-82. doi: 10.1158/1078-0432.CCR-09-3275. Epub 2010 Apr 6.

39.

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

Dopeso H, Mateo-Lozano S, Mazzolini R, Rodrigues P, Lagares-Tena L, Ceron J, Romero J, Esteves M, Landolfi S, Hernández-Losa J, Castaño J, Wilson AJ, Ramon y Cajal S, Mariadason JM, Schwartz S Jr, Arango D.

Cancer Res. 2009 Sep 15;69(18):7430-8. doi: 10.1158/0008-5472.CAN-09-0706. Epub 2009 Sep 8.

40.

Risk factors for positive findings in patients with high-grade T1 bladder cancer treated with transurethral resection of bladder tumour (TUR) and bacille Calmette-Guérin therapy and the decision for a repeat TUR.

Orsola A, Cecchini L, Raventós CX, Trilla E, Planas J, Landolfi S, de Torres I, Morote J.

BJU Int. 2010 Jan;105(2):202-7. doi: 10.1111/j.1464-410X.2009.08694.x. Epub 2009 Jun 24.

41.

[Schistosomiasis as a cause of acute appendicitis].

Señuque Artini M, López de Cenarruzabeitia I, Rodríguez Conde N, Landolfi S, Armengol Carrasco M.

Cir Esp. 2009 Jun;85(6):387-9. doi: 10.1016/j.ciresp.2008.05.002. Epub 2009 Apr 29. Spanish. No abstract available.

PMID:
19406390
42.

Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity.

Scaltriti M, Verma C, Guzman M, Jimenez J, Parra JL, Pedersen K, Smith DJ, Landolfi S, Ramon y Cajal S, Arribas J, Baselga J.

Oncogene. 2009 Feb 12;28(6):803-14. doi: 10.1038/onc.2008.432. Epub 2008 Dec 8.

PMID:
19060928
43.

p16 INK4a immunostaining identifies occult CIN lesions in HPV-positive women.

Ordi J, Garcia S, del Pino M, Landolfi S, Alonso I, Quintó L, Torné A.

Int J Gynecol Pathol. 2009 Jan;28(1):90-7. doi: 10.1097/PGP.0b013e31817e9ac5.

PMID:
19047902
44.

Pre-operative chemoradiotherapy with UFT and Leucovorin in patients with advanced rectal cancer: a phase II study.

Giralt J, Tabernero J, Navalpotro B, Capdevila J, Espin E, Casado E, Mañes A, Landolfi S, Sanchez-Garcia JL, de Torres I, Armengol M.

Radiother Oncol. 2008 Dec;89(3):263-9. doi: 10.1016/j.radonc.2008.07.010. Epub 2008 Sep 1.

PMID:
18768230
45.

[Neuroendocrine carcinomas of the colon and rectum. A unit's experience over six years].

Vilallonga R, Espín Basany E, López Cano M, Landolfi S, Armengol Carrasco M.

Rev Esp Enferm Dig. 2008 Jan;100(1):11-6. Review. Spanish.

46.

p16 overexpression identifies HPV-positive vulvar squamous cell carcinomas.

Santos M, Landolfi S, Olivella A, Lloveras B, Klaustermeier J, Suárez H, Alòs L, Puig-Tintoré LM, Campo E, Ordi J.

Am J Surg Pathol. 2006 Nov;30(11):1347-56.

PMID:
17063073
47.

Poorly differentiated carcinomas of the thyroid with trabecular, insular, and solid patterns: a clinicopathologic study of 183 patients.

Volante M, Landolfi S, Chiusa L, Palestini N, Motta M, Codegone A, Torchio B, Papotti MG.

Cancer. 2004 Mar 1;100(5):950-7.

48.

Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis.

Papotti M, Bongiovanni M, Volante M, Allìa E, Landolfi S, Helboe L, Schindler M, Cole SL, Bussolati G.

Virchows Arch. 2002 May;440(5):461-75. Epub 2002 Mar 23.

PMID:
12021920
49.

Specific haplotypes of the RET proto-oncogene are over-represented in patients with sporadic papillary thyroid carcinoma.

Lesueur F, Corbex M, McKay JD, Lima J, Soares P, Griseri P, Burgess J, Ceccherini I, Landolfi S, Papotti M, Amorim A, Goldgar DE, Romeo G.

J Med Genet. 2002 Apr;39(4):260-5.

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