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Items: 1 to 50 of 134

1.

The fifty years it has taken to understand the dynamics of UO<sub>2</sub> in its ordered state.

Lander GH, Caciuffo R.

J Phys Condens Matter. 2019 Apr 29. doi: 10.1088/1361-648X/ab1dc5. [Epub ahead of print]

PMID:
31035272
2.

Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry.

Rollins MF, Chowdhury S, Carter J, Golden SM, Miettinen HM, Santiago-Frangos A, Faith D, Lawrence CM, Lander GC, Wiedenheft B.

Mol Cell. 2019 Apr 4;74(1):132-142.e5. doi: 10.1016/j.molcel.2019.02.001. Epub 2019 Mar 11.

PMID:
30872121
3.

High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM.

Herzik MA Jr, Wu M, Lander GC.

Nat Commun. 2019 Mar 4;10(1):1032. doi: 10.1038/s41467-019-08991-8.

4.

The rod-shaped ATG2A-WIPI4 complex tethers membranes in vitro.

Otomo T, Chowdhury S, Lander GC.

Contact (Thousand Oaks). 2018 Jan-Dec;1. doi: 10.1177/2515256418819936. Epub 2018 Dec 21.

5.

A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality.

Herzik MA Jr, Fraser JS, Lander GC.

Structure. 2019 Feb 5;27(2):344-358.e3. doi: 10.1016/j.str.2018.10.003. Epub 2018 Nov 15.

PMID:
30449687
6.

Conformational ensemble of the human TRPV3 ion channel.

Zubcevic L, Herzik MA Jr, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY.

Nat Commun. 2018 Nov 14;9(1):4773. doi: 10.1038/s41467-018-07117-w.

7.

Substrate-engaged 26S proteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.

de la Peña AH, Goodall EA, Gates SN, Lander GC, Martin A.

Science. 2018 Nov 30;362(6418). pii: eaav0725. doi: 10.1126/science.aav0725. Epub 2018 Oct 11.

PMID:
30309908
8.

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex.

Chowdhury S, Otomo C, Leitner A, Ohashi K, Aebersold R, Lander GC, Otomo T.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9792-E9801. doi: 10.1073/pnas.1811874115. Epub 2018 Sep 5.

9.

Cryo-EM structure of a mitochondrial calcium uniporter.

Yoo J, Wu M, Yin Y, Herzik MA Jr, Lander GC, Lee SY.

Science. 2018 Aug 3;361(6401):506-511. doi: 10.1126/science.aar4056. Epub 2018 Jun 28.

10.

B. T. M. (Terry) Willis (1927-2018).

Lander G, Carlile C.

Acta Crystallogr A Found Adv. 2018 May 1;74(Pt 3):287-288. doi: 10.1107/S2053273318004291. Epub 2018 Mar 27. No abstract available.

PMID:
29724971
11.

Exploring applications of crowdsourcing to cryo-EM.

Bruggemann J, Lander GC, Su AI.

J Struct Biol. 2018 Jul;203(1):37-45. doi: 10.1016/j.jsb.2018.02.006. Epub 2018 Feb 24.

12.

Author Correction: Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility.

Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC.

Nat Struct Mol Biol. 2018 Apr;25(4):355. doi: 10.1038/s41594-018-0043-7.

PMID:
29476122
13.

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility.

Grotjahn DA, Chowdhury S, Xu Y, McKenney RJ, Schroer TA, Lander GC.

Nat Struct Mol Biol. 2018 Mar;25(3):203-207. doi: 10.1038/s41594-018-0027-7. Epub 2018 Feb 7. Erratum in: Nat Struct Mol Biol. 2018 Feb 23;:.

14.

The peroxisomal AAA-ATPase Pex1/Pex6 unfolds substrates by processive threading.

Gardner BM, Castanzo DT, Chowdhury S, Stjepanovic G, Stefely MS, Hurley JH, Lander GC, Martin A.

Nat Commun. 2018 Jan 10;9(1):135. doi: 10.1038/s41467-017-02474-4.

15.

Structure of the cold- and menthol-sensing ion channel TRPM8.

Yin Y, Wu M, Zubcevic L, Borschel WF, Lander GC, Lee SY.

Science. 2018 Jan 12;359(6372):237-241. doi: 10.1126/science.aan4325. Epub 2017 Dec 7.

16.

Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing.

Puchades C, Rampello AJ, Shin M, Giuliano CJ, Wiseman RL, Glynn SE, Lander GC.

Science. 2017 Nov 3;358(6363). pii: eaao0464. doi: 10.1126/science.aao0464.

17.

Probing Magnetism in the Vortex Phase of PuCoGa_{5} by X-Ray Magnetic Circular Dichroism.

Magnani N, Eloirdi R, Wilhelm F, Colineau E, Griveau JC, Shick AB, Lander GH, Rogalev A, Caciuffo R.

Phys Rev Lett. 2017 Oct 13;119(15):157204. doi: 10.1103/PhysRevLett.119.157204. Epub 2017 Oct 12.

PMID:
29077471
18.

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection.

Chen D, Lander GR, Flagg EB.

J Vis Exp. 2017 Oct 13;(128). doi: 10.3791/56435.

PMID:
29053692
19.

Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.

Hirschi M, Herzik MA Jr, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY.

Nature. 2017 Oct 19;550(7676):411-414. doi: 10.1038/nature24055. Epub 2017 Oct 11.

20.

Achieving better-than-3-Å resolution by single-particle cryo-EM at 200 keV.

Herzik MA Jr, Wu M, Lander GC.

Nat Methods. 2017 Nov;14(11):1075-1078. doi: 10.1038/nmeth.4461. Epub 2017 Oct 9.

21.

The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.

Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL.

EMBO J. 2017 Aug 1;36(15):2296-2309. doi: 10.15252/embj.201695616. Epub 2017 Jun 27.

22.

Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.

Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5113-E5121. doi: 10.1073/pnas.1616395114. Epub 2017 Apr 24.

23.

Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex.

Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL, Davidson AR, Fischer ER, Lander GC, Wiedenheft B.

Cell. 2017 Mar 23;169(1):47-57.e11. doi: 10.1016/j.cell.2017.03.012.

24.

Polarization-Dependent Interference of Coherent Scattering from Orthogonal Dipole Moments of a Resonantly Excited Quantum Dot.

Chen D, Lander GR, Solomon GS, Flagg EB.

Phys Rev Lett. 2017 Jan 20;118(3):037401. doi: 10.1103/PhysRevLett.118.037401. Epub 2017 Jan 20.

PMID:
28157367
25.

Relevance of Kondo physics for the temperature dependence of the bulk modulus in plutonium.

Janoschek M, Lander G, Lawrence JM, Bauer ED, Lashley JC, Lumsden M, Abernathy DL, Thompson JD.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E268. doi: 10.1073/pnas.1618967114. Epub 2017 Jan 10. No abstract available.

26.

What's the Key to Unlocking the Proteasome's Gate?

de la Peña AH, Lander GC.

Structure. 2016 Dec 6;24(12):2037-2038. doi: 10.1016/j.str.2016.11.011.

27.

Isolation of yeast complex IV in native lipid nanodiscs.

Smirnova IA, Sjöstrand D, Li F, Björck M, Schäfer J, Östbye H, Högbom M, von Ballmoos C, Lander GC, Ädelroth P, Brzezinski P.

Biochim Biophys Acta. 2016 Dec;1858(12):2984-2992. doi: 10.1016/j.bbamem.2016.09.004. Epub 2016 Sep 13.

28.

A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.

Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J, Carmel G, Tran T, Riley M, Nosaka L, Lander GC, Gaidarova S, Xu S, Ruchelman AL, Handa H, Carmichael J, Daniel TO, Cathers BE, Lopez-Girona A, Chamberlain PP.

Nature. 2016 Jul 14;535(7611):252-7. doi: 10.1038/nature18611. Epub 2016 Jun 22.

PMID:
27338790
29.

Cryo-electron microscopy structure of the TRPV2 ion channel.

Zubcevic L, Herzik MA Jr, Chung BC, Liu Z, Lander GC, Lee SY.

Nat Struct Mol Biol. 2016 Feb;23(2):180-186. doi: 10.1038/nsmb.3159. Epub 2016 Jan 18.

30.

Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition.

Dambacher CM, Worden EJ, Herzik MA, Martin A, Lander GC.

Elife. 2016 Jan 8;5:e13027. doi: 10.7554/eLife.13027.

31.

The valence-fluctuating ground state of plutonium.

Janoschek M, Das P, Chakrabarti B, Abernathy DL, Lumsden MD, Lawrence JM, Thompson JD, Lander GH, Mitchell JN, Richmond S, Ramos M, Trouw F, Zhu JX, Haule K, Kotliar G, Bauer ED.

Sci Adv. 2015 Jul 10;1(6):e1500188. doi: 10.1126/sciadv.1500188. eCollection 2015 Jul.

32.

Thermodynamic Interrogation of the Assembly of a Viral Genome Packaging Motor Complex.

Yang TC, Ortiz D, Nosaka L, Lander GC, Catalano CE.

Biophys J. 2015 Oct 20;109(8):1663-75. doi: 10.1016/j.bpj.2015.08.037.

33.

Protein domain mapping by internal labeling and single particle electron microscopy.

Ciferri C, Lander GC, Nogales E.

J Struct Biol. 2015 Nov;192(2):159-62. doi: 10.1016/j.jsb.2015.09.016. Epub 2015 Sep 30.

34.

Site-specific labeling of proteins for electron microscopy.

Dambacher CM, Lander GC.

J Struct Biol. 2015 Nov;192(2):151-8. doi: 10.1016/j.jsb.2015.09.010. Epub 2015 Sep 25.

35.

Ubp6 deubiquitinase controls conformational dynamics and substrate degradation of the 26S proteasome.

Bashore C, Dambacher CM, Goodall EA, Matyskiela ME, Lander GC, Martin A.

Nat Struct Mol Biol. 2015 Sep;22(9):712-9. doi: 10.1038/nsmb.3075. Epub 2015 Aug 24.

36.

Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22.

McNulty R, Lokareddy RK, Roy A, Yang Y, Lander GC, Heck AJR, Johnson JE, Cingolani G.

J Mol Biol. 2015 Oct 9;427(20):3285-3299. doi: 10.1016/j.jmb.2015.08.013. Epub 2015 Aug 21.

37.

Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.

Garnham CP, Vemu A, Wilson-Kubalek EM, Yu I, Szyk A, Lander GC, Milligan RA, Roll-Mecak A.

Cell. 2015 May 21;161(5):1112-1123. doi: 10.1016/j.cell.2015.04.003. Epub 2015 May 7.

38.

Water corrosion of spent nuclear fuel: radiolysis driven dissolution at the UO2/water interface.

Springell R, Rennie S, Costelle L, Darnbrough J, Stitt C, Cocklin E, Lucas C, Burrows R, Sims H, Wermeille D, Rawle J, Nicklin C, Nuttall W, Scott T, Lander G.

Faraday Discuss. 2015;180:301-11. doi: 10.1039/c4fd00254g.

PMID:
25932469
39.

Magnetic polarization of the americium J=0 ground state in AmFe(2).

Magnani N, Caciuffo R, Wilhelm F, Colineau E, Eloirdi R, Griveau JC, Rusz J, Oppeneer PM, Rogalev A, Lander GH.

Phys Rev Lett. 2015 Mar 6;114(9):097203. Epub 2015 Mar 6.

PMID:
25793847
40.

Structural organization of the dynein-dynactin complex bound to microtubules.

Chowdhury S, Ketcham SA, Schroer TA, Lander GC.

Nat Struct Mol Biol. 2015 Apr;22(4):345-7. doi: 10.1038/nsmb.2996. Epub 2015 Mar 9.

41.

The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.

Gardner BM, Chowdhury S, Lander GC, Martin A.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1375-1388. doi: 10.1016/j.jmb.2015.01.019. Epub 2015 Feb 7.

42.

Solid-to-fluid-like DNA transition in viruses facilitates infection.

Liu T, Sae-Ueng U, Li D, Lander GC, Zuo X, Jönsson B, Rau D, Shefer I, Evilevitch A.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14675-80. doi: 10.1073/pnas.1321637111. Epub 2014 Sep 30. Erratum in: Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2410.

43.

High-resolution microtubule structures reveal the structural transitions in αβ-tubulin upon GTP hydrolysis.

Alushin GM, Lander GC, Kellogg EH, Zhang R, Baker D, Nogales E.

Cell. 2014 May 22;157(5):1117-29. doi: 10.1016/j.cell.2014.03.053.

44.

Distinct magnetic phase transition at the surface of an antiferromagnet.

Langridge S, Watson GM, Gibbs D, Betouras JJ, Gidopoulos NI, Pollmann F, Long MW, Vettier C, Lander GH.

Phys Rev Lett. 2014 Apr 25;112(16):167201. Epub 2014 Apr 22.

PMID:
24815664
45.

Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy.

Zhao Q, Potter CS, Carragher B, Lander G, Sworen J, Towne V, Abraham D, Duncan P, Washabaugh MW, Sitrin RD.

Hum Vaccin Immunother. 2014;10(3):734-9. Epub 2013 Dec 3.

46.

Conformational switching of the 26S proteasome enables substrate degradation.

Matyskiela ME, Lander GC, Martin A.

Nat Struct Mol Biol. 2013 Jul;20(7):781-8. doi: 10.1038/nsmb.2616. Epub 2013 Jun 16.

47.

The proteasome under the microscope: the regulatory particle in focus.

Lander GC, Martin A, Nogales E.

Curr Opin Struct Biol. 2013 Apr;23(2):243-51. doi: 10.1016/j.sbi.2013.02.004. Epub 2013 Mar 13. Review.

48.

DNA bending-induced phase transition of encapsidated genome in phage λ.

Lander GC, Johnson JE, Rau DC, Potter CS, Carragher B, Evilevitch A.

Nucleic Acids Res. 2013 Apr;41(8):4518-24. doi: 10.1093/nar/gkt137. Epub 2013 Feb 28.

49.

Molecular architecture of human polycomb repressive complex 2.

Ciferri C, Lander GC, Maiolica A, Herzog F, Aebersold R, Nogales E.

Elife. 2012 Oct 30;1:e00005. doi: 10.7554/eLife.00005.

50.

Go hybrid: EM, crystallography, and beyond.

Lander GC, Saibil HR, Nogales E.

Curr Opin Struct Biol. 2012 Oct;22(5):627-35. doi: 10.1016/j.sbi.2012.07.006. Epub 2012 Jul 24. Review.

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