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Items: 11

1.

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils.

Russo I, Kaganovich A, Ding J, Landeck N, Mamais A, Varanita T, Biosa A, Tessari I, Bubacco L, Greggio E, Cookson MR.

Neurobiol Dis. 2019 Sep;129:67-78. doi: 10.1016/j.nbd.2019.05.012. Epub 2019 May 15.

PMID:
31102768
2.

Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs.

Lillethorup TP, Glud AN, Alstrup AKO, Noer O, Nielsen EHT, Schacht AC, Landeck N, Kirik D, Orlowski D, Sørensen JCH, Doudet DJ, Landau AM.

Sci Rep. 2018 Oct 24;8(1):15715. doi: 10.1038/s41598-018-34084-5.

3.

In vivo quantification of glial activation in minipigs overexpressing human α-synuclein.

Lillethorup TP, Glud AN, Landeck N, Alstrup AKO, Jakobsen S, Vang K, Doudet DJ, Brooks DJ, Kirik D, Hinz R, Sørensen JC, Landau AM.

Synapse. 2018 Dec;72(12):e22060. doi: 10.1002/syn.22060. Epub 2018 Aug 12.

PMID:
30009467
4.

Toxic effects of human and rodent variants of alpha-synuclein in vivo.

Landeck N, Buck K, Kirik D.

Eur J Neurosci. 2017 Feb;45(4):536-547. doi: 10.1111/ejn.13493. Epub 2017 Jan 11.

PMID:
27893183
5.

A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein.

Landeck N, Hall H, Ardah MT, Majbour NK, El-Agnaf OM, Halliday G, Kirik D.

Mol Neurodegener. 2016 Aug 22;11(1):61. doi: 10.1186/s13024-016-0125-0.

6.

Assessment of brain metabolite correlates of adeno-associated virus-mediated over-expression of human alpha-synuclein in cortical neurons by in vivo (1) H-MR spectroscopy at 9.4 T.

Cuellar-Baena S, Landeck N, Sonnay S, Buck K, Mlynarik V, In 't Zandt R, Kirik D.

J Neurochem. 2016 Jun;137(5):806-19. doi: 10.1111/jnc.13547. Epub 2016 Feb 17.

7.

Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.

Buck K, Landeck N, Ulusoy A, Majbour NK, El-Agnaf OM, Kirik D.

Neurobiol Dis. 2015 Jun;78:100-14. doi: 10.1016/j.nbd.2015.03.008. Epub 2015 Mar 25.

PMID:
25818009
8.

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

Hall H, Reyes S, Landeck N, Bye C, Leanza G, Double K, Thompson L, Halliday G, Kirik D.

Brain. 2014 Sep;137(Pt 9):2493-508. doi: 10.1093/brain/awu193. Epub 2014 Jul 24.

PMID:
25062696
9.

Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration.

Xilouri M, Brekk OR, Landeck N, Pitychoutis PM, Papasilekas T, Papadopoulou-Daifoti Z, Kirik D, Stefanis L.

Brain. 2013 Jul;136(Pt 7):2130-46. doi: 10.1093/brain/awt131. Epub 2013 Jun 11.

PMID:
23757764
10.

Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors.

Hall H, Jewett M, Landeck N, Nilsson N, Schagerlöf U, Leanza G, Kirik D.

PLoS One. 2013 May 21;8(5):e64844. doi: 10.1371/journal.pone.0064844. Print 2013.

11.

Rapid, reproducible transduction of select forebrain regions by targeted recombinant virus injection into the neonatal mouse brain.

Pilpel N, Landeck N, Klugmann M, Seeburg PH, Schwarz MK.

J Neurosci Methods. 2009 Aug 30;182(1):55-63. doi: 10.1016/j.jneumeth.2009.05.020. Epub 2009 Jun 6.

PMID:
19505498

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