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Items: 1 to 50 of 232

1.

Twenty Years of "Lipid World": A Fertile Partnership with David Deamer.

Lancet D, Segrè D, Kahana A.

Life (Basel). 2019 Sep 20;9(4). pii: E77. doi: 10.3390/life9040077. Review.

2.

Enceladus: First Observed Primordial Soup Could Arbitrate Origin-of-Life Debate.

Kahana A, Schmitt-Kopplin P, Lancet D.

Astrobiology. 2019 Oct;19(10):1263-1278. doi: 10.1089/ast.2019.2029. Epub 2019 Jul 22.

3.

Noncoding deletions reveal a gene that is critical for intestinal function.

Oz-Levi D, Olender T, Bar-Joseph I, Zhu Y, Marek-Yagel D, Barozzi I, Osterwalder M, Alkelai A, Ruzzo EK, Han Y, Vos ESM, Reznik-Wolf H, Hartman C, Shamir R, Weiss B, Shapiro R, Pode-Shakked B, Tatarskyy P, Milgrom R, Schvimer M, Barshack I, Imai DM, Coleman-Derr D, Dickel DE, Nord AS, Afzal V, van Bueren KL, Barnes RM, Black BL, Mayhew CN, Kuhar MF, Pitstick A, Tekman M, Stanescu HC, Wells JM, Kleta R, de Laat W, Goldstein DB, Pras E, Visel A, Lancet D, Anikster Y, Pennacchio LA.

Nature. 2019 Jul;571(7763):107-111. doi: 10.1038/s41586-019-1312-2. Epub 2019 Jun 19.

4.

Protobiotic Systems Chemistry Analyzed by Molecular Dynamics.

Kahana A, Lancet D.

Life (Basel). 2019 May 10;9(2). pii: E38. doi: 10.3390/life9020038. Review.

5.

Systems protobiology: origin of life in lipid catalytic networks.

Lancet D, Zidovetzki R, Markovitch O.

J R Soc Interface. 2018 Jul;15(144). pii: 20180159. doi: 10.1098/rsif.2018.0159. Review.

6.

Replication of Simulated Prebiotic Amphiphilic Vesicles in a Finite Environment Exhibits Complex Behavior That Includes High Progeny Variability and Competition.

Armstrong DL, Lancet D, Zidovetzki R.

Astrobiology. 2018 Apr;18(4):419-430. doi: 10.1089/ast.2016.1615. Epub 2018 Mar 16.

7.

Next-generation sequencing of patients with congenital anosmia.

Alkelai A, Olender T, Dode C, Shushan S, Tatarskyy P, Furman-Haran E, Boyko V, Gross-Isseroff R, Halvorsen M, Greenbaum L, Milgrom R, Yamada K, Haneishi A, Blau I, Lancet D.

Eur J Hum Genet. 2017 Dec;25(12):1377-1387. doi: 10.1038/s41431-017-0014-1. Epub 2017 Nov 13.

8.

Mutations in AIFM1 cause an X-linked childhood cerebellar ataxia partially responsive to riboflavin.

Heimer G, Eyal E, Zhu X, Ruzzo EK, Marek-Yagel D, Sagiv D, Anikster Y, Reznik-Wolf H, Pras E, Oz Levi D, Lancet D, Ben-Zeev B, Nissenkorn A.

Eur J Paediatr Neurol. 2018 Jan;22(1):93-101. doi: 10.1016/j.ejpn.2017.09.004. Epub 2017 Sep 15.

PMID:
28967629
9.

Rational confederation of genes and diseases: NGS interpretation via GeneCards, MalaCards and VarElect.

Rappaport N, Fishilevich S, Nudel R, Twik M, Belinky F, Plaschkes I, Stein TI, Cohen D, Oz-Levi D, Safran M, Lancet D.

Biomed Eng Online. 2017 Aug 18;16(Suppl 1):72. doi: 10.1186/s12938-017-0359-2.

10.

GeneHancer: genome-wide integration of enhancers and target genes in GeneCards.

Fishilevich S, Nudel R, Rappaport N, Hadar R, Plaschkes I, Iny Stein T, Rosen N, Kohn A, Twik M, Safran M, Lancet D, Cohen D.

Database (Oxford). 2017 Jan 1;2017. doi: 10.1093/database/bax028.

11.

MalaCards: an amalgamated human disease compendium with diverse clinical and genetic annotation and structured search.

Rappaport N, Twik M, Plaschkes I, Nudel R, Iny Stein T, Levitt J, Gershoni M, Morrey CP, Safran M, Lancet D.

Nucleic Acids Res. 2017 Jan 4;45(D1):D877-D887. doi: 10.1093/nar/gkw1012. Epub 2016 Nov 28. Review.

12.

ORDB, HORDE, ODORactor and other on-line knowledge resources of olfactory receptor-odorant interactions.

Marenco L, Wang R, McDougal R, Olender T, Twik M, Bruford E, Liu X, Zhang J, Lancet D, Shepherd G, Crasto C.

Database (Oxford). 2016 Oct 2;2016. pii: baw132. Print 2016.

13.

The human olfactory transcriptome.

Olender T, Keydar I, Pinto JM, Tatarskyy P, Alkelai A, Chien MS, Fishilevich S, Restrepo D, Matsunami H, Gilad Y, Lancet D.

BMC Genomics. 2016 Aug 11;17(1):619. doi: 10.1186/s12864-016-2960-3.

14.

VarElect: the phenotype-based variation prioritizer of the GeneCards Suite.

Stelzer G, Plaschkes I, Oz-Levi D, Alkelai A, Olender T, Zimmerman S, Twik M, Belinky F, Fishilevich S, Nudel R, Guan-Golan Y, Warshawsky D, Dahary D, Kohn A, Mazor Y, Kaplan S, Iny Stein T, Baris HN, Rappaport N, Safran M, Lancet D.

BMC Genomics. 2016 Jun 23;17 Suppl 2:444. doi: 10.1186/s12864-016-2722-2.

15.

The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses.

Stelzer G, Rosen N, Plaschkes I, Zimmerman S, Twik M, Fishilevich S, Stein TI, Nudel R, Lieder I, Mazor Y, Kaplan S, Dahary D, Warshawsky D, Guan-Golan Y, Kohn A, Rappaport N, Safran M, Lancet D.

Curr Protoc Bioinformatics. 2016 Jun 20;54:1.30.1-1.30.33. doi: 10.1002/cpbi.5.

PMID:
27322403
16.

Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene.

Vodo D, Sarig O, Geller S, Ben-Asher E, Olender T, Bochner R, Goldberg I, Nosgorodsky J, Alkelai A, Tatarskyy P, Peled A, Baum S, Barzilai A, Ibrahim SM, Zillikens D, Lancet D, Sprecher E.

PLoS Genet. 2016 May 5;12(5):e1006008. doi: 10.1371/journal.pgen.1006008. eCollection 2016 May.

17.

Genic insights from integrated human proteomics in GeneCards.

Fishilevich S, Zimmerman S, Kohn A, Iny Stein T, Olender T, Kolker E, Safran M, Lancet D.

Database (Oxford). 2016 Apr 5;2016. pii: baw030. doi: 10.1093/database/baw030. Print 2016.

18.

A role for TENM1 mutations in congenital general anosmia.

Alkelai A, Olender T, Haffner-Krausz R, Tsoory MM, Boyko V, Tatarskyy P, Gross-Isseroff R, Milgrom R, Shushan S, Blau I, Cohn E, Beeri R, Levy-Lahad E, Pras E, Lancet D.

Clin Genet. 2016 Sep;90(3):211-9. doi: 10.1111/cge.12782. Epub 2016 May 31.

PMID:
27040985
19.

GeneAnalytics: An Integrative Gene Set Analysis Tool for Next Generation Sequencing, RNAseq and Microarray Data.

Ben-Ari Fuchs S, Lieder I, Stelzer G, Mazor Y, Buzhor E, Kaplan S, Bogoch Y, Plaschkes I, Shitrit A, Rappaport N, Kohn A, Edgar R, Shenhav L, Safran M, Lancet D, Guan-Golan Y, Warshawsky D, Shtrichman R.

OMICS. 2016 Mar;20(3):139-51. doi: 10.1089/omi.2015.0168.

20.

TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability.

Heimer G, Oz-Levi D, Eyal E, Edvardson S, Nissenkorn A, Ruzzo EK, Szeinberg A, Maayan C, Mai-Zahav M, Efrati O, Pras E, Reznik-Wolf H, Lancet D, Goldstein DB, Anikster Y, Shalev SA, Elpeleg O, Ben Zeev B.

Eur J Paediatr Neurol. 2016 Jan;20(1):69-79. doi: 10.1016/j.ejpn.2015.10.003. Epub 2015 Oct 22.

PMID:
26542466
21.

Molecular disease presentation in diabetic nephropathy.

Heinzel A, Mühlberger I, Stelzer G, Lancet D, Oberbauer R, Martin M, Perco P.

Nephrol Dial Transplant. 2015 Aug;30 Suppl 4:iv17-25. doi: 10.1093/ndt/gfv267. Review.

PMID:
26209734
22.

SLC1A4 mutations cause a novel disorder of intellectual disability, progressive microcephaly, spasticity and thin corpus callosum.

Heimer G, Marek-Yagel D, Eyal E, Barel O, Oz Levi D, Hoffmann C, Ruzzo EK, Ganelin-Cohen E, Lancet D, Pras E, Rechavi G, Nissenkorn A, Anikster Y, Goldstein DB, Ben Zeev B.

Clin Genet. 2015 Oct;88(4):327-35. doi: 10.1111/cge.12637. Epub 2015 Jul 28.

PMID:
26138499
23.

PathCards: multi-source consolidation of human biological pathways.

Belinky F, Nativ N, Stelzer G, Zimmerman S, Iny Stein T, Safran M, Lancet D.

Database (Oxford). 2015 Feb 27;2015. pii: bav006. doi: 10.1093/database/bav006. Print 2015.

24.

Whole-exome sequencing in undiagnosed genetic diseases: interpreting 119 trios.

Zhu X, Petrovski S, Xie P, Ruzzo EK, Lu YF, McSweeney KM, Ben-Zeev B, Nissenkorn A, Anikster Y, Oz-Levi D, Dhindsa RS, Hitomi Y, Schoch K, Spillmann RC, Heimer G, Marek-Yagel D, Tzadok M, Han Y, Worley G, Goldstein J, Jiang YH, Lancet D, Pras E, Shashi V, McHale D, Need AC, Goldstein DB.

Genet Med. 2015 Oct;17(10):774-81. doi: 10.1038/gim.2014.191. Epub 2015 Jan 15.

25.

Quasispecies in population of compositional assemblies.

Gross R, Fouxon I, Lancet D, Markovitch O.

BMC Evol Biol. 2014 Dec 30;14:265. doi: 10.1186/s12862-014-0265-1.

26.

Exome sequencing as a differential diagnosis tool: resolving mild trichohepatoenteric syndrome.

Oz-Levi D, Weiss B, Lahad A, Greenberger S, Pode-Shakked B, Somech R, Olender T, Tatarsky P, Marek-Yagel D, Pras E, Anikster Y, Lancet D.

Clin Genet. 2015 Jun;87(6):602-3. doi: 10.1111/cge.12494. Epub 2014 Oct 21. No abstract available.

PMID:
25335910
27.

MalaCards: A Comprehensive Automatically-Mined Database of Human Diseases.

Rappaport N, Twik M, Nativ N, Stelzer G, Bahir I, Stein TI, Safran M, Lancet D.

Curr Protoc Bioinformatics. 2014 Sep 8;47:1.24.1-19. doi: 10.1002/0471250953.bi0124s47.

PMID:
25199789
28.

Multispecies population dynamics of prebiotic compositional assemblies.

Markovitch O, Lancet D.

J Theor Biol. 2014 Sep 21;357:26-34. doi: 10.1016/j.jtbi.2014.05.005. Epub 2014 May 14.

PMID:
24831416
29.

The MATCHIT automaton: exploiting compartmentalization for the synthesis of branched polymers.

Weyland MS, Fellermann H, Hadorn M, Sorek D, Lancet D, Rasmussen S, Füchslin RM.

Comput Math Methods Med. 2013;2013:467428. doi: 10.1155/2013/467428. Epub 2013 Dec 31.

30.

Toward more transparent and reproducible omics studies through a common metadata checklist and data publications.

Kolker E, Özdemir V, Martens L, Hancock W, Anderson G, Anderson N, Aynacioglu S, Baranova A, Campagna SR, Chen R, Choiniere J, Dearth SP, Feng WC, Ferguson L, Fox G, Frishman D, Grossman R, Heath A, Higdon R, Hutz MH, Janko I, Jiang L, Joshi S, Kel A, Kemnitz JW, Kohane IS, Kolker N, Lancet D, Lee E, Li W, Lisitsa A, Llerena A, Macnealy-Koch C, Marshall JC, Masuzzo P, May A, Mias G, Monroe M, Montague E, Mooney S, Nesvizhskii A, Noronha S, Omenn G, Rajasimha H, Ramamoorthy P, Sheehan J, Smarr L, Smith CV, Smith T, Snyder M, Rapole S, Srivastava S, Stanberry L, Stewart E, Toppo S, Uetz P, Verheggen K, Voy BH, Warnich L, Wilhelm SW, Yandl G.

OMICS. 2014 Jan;18(1):10-4. doi: 10.1089/omi.2013.0149.

31.

MOPED enables discoveries through consistently processed proteomics data.

Higdon R, Stewart E, Stanberry L, Haynes W, Choiniere J, Montague E, Anderson N, Yandl G, Janko I, Broomall W, Fishilevich S, Lancet D, Kolker N, Kolker E.

J Proteome Res. 2014 Jan 3;13(1):107-13. doi: 10.1021/pr400884c. Epub 2013 Dec 18.

32.

Toward More Transparent and Reproducible Omics Studies Through a Common Metadata Checklist and Data Publications.

Kolker E, Özdemir V, Martens L, Hancock W, Anderson G, Anderson N, Aynacioglu S, Baranova A, Campagna SR, Chen R, Choiniere J, Dearth SP, Feng WC, Ferguson L, Fox G, Frishman D, Grossman R, Heath A, Higdon R, Hutz MH, Janko I, Jiang L, Joshi S, Kel A, Kemnitz JW, Kohane IS, Kolker N, Lancet D, Lee E, Li W, Lisitsa A, Llerena A, MacNealy-Koch C, Marshall JC, Masuzzo P, May A, Mias G, Monroe M, Montague E, Mooney S, Nesvizhskii A, Noronha S, Omenn G, Rajasimha H, Ramamoorthy P, Sheehan J, Smarr L, Smith CV, Smith T, Snyder M, Rapole S, Srivastava S, Stanberry L, Stewart E, Toppo S, Uetz P, Verheggen K, Voy BH, Warnich L, Wilhelm SW, Yandl G.

Big Data. 2013 Dec;1(4):196-201. doi: 10.1089/big.2013.0039.

PMID:
27447251
33.

Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.

Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, Lerman-Sagie T, Leshinsky-Silver E, Anikster Y, Ben-Asher E, Olender T, Colleaux L, Décarie JC, Blaser S, Banwell B, Joshi RB, He XP, Patry L, Silver RJ, Dobrzeniecka S, Islam MS, Hasnat A, Samuels ME, Aryal DK, Rodriguiz RM, Jiang YH, Wetsel WC, McNamara JO, Rouleau GA, Silver DL, Lancet D, Pras E, Mitchell GA, Michaud JL, Goldstein DB.

Neuron. 2013 Oct 16;80(2):429-41. doi: 10.1016/j.neuron.2013.08.013.

34.

Reproducibility: In praise of open research measures.

Kolker E, Altintas I, Bourne P, Faris J, Fox G, Frishman D, Geraci C, Hancock W, Lin B, Lancet D, Lisitsa A, Knight R, Martens L, Mesirov J, Özdemir V, Schultes E, Smith T, Snyder M, Srivastava S, Toppo S, Wilmes P.

Nature. 2013 Jun 13;498(7453):170. doi: 10.1038/498170b. No abstract available.

PMID:
23765483
35.

HORDE: comprehensive resource for olfactory receptor genomics.

Olender T, Nativ N, Lancet D.

Methods Mol Biol. 2013;1003:23-38. doi: 10.1007/978-1-62703-377-0_2.

PMID:
23585031
36.

MalaCards: an integrated compendium for diseases and their annotation.

Rappaport N, Nativ N, Stelzer G, Twik M, Guan-Golan Y, Stein TI, Bahir I, Belinky F, Morrey CP, Safran M, Lancet D.

Database (Oxford). 2013 Apr 12;2013:bat018. doi: 10.1093/database/bat018. Print 2013.

37.

TECPR2: a new autophagy link for neurodegeneration.

Oz-Levi D, Gelman A, Elazar Z, Lancet D.

Autophagy. 2013 May;9(5):801-2. doi: 10.4161/auto.23961. Epub 2013 Feb 25.

38.

Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis.

Oz-Levi D, Ben-Zeev B, Ruzzo EK, Hitomi Y, Gelman A, Pelak K, Anikster Y, Reznik-Wolf H, Bar-Joseph I, Olender T, Alkelai A, Weiss M, Ben-Asher E, Ge D, Shianna KV, Elazar Z, Goldstein DB, Pras E, Lancet D.

Am J Hum Genet. 2012 Dec 7;91(6):1065-72. doi: 10.1016/j.ajhg.2012.09.015. Epub 2012 Nov 21.

39.

Non-redundant compendium of human ncRNA genes in GeneCards.

Belinky F, Bahir I, Stelzer G, Zimmerman S, Rosen N, Nativ N, Dalah I, Iny Stein T, Rappaport N, Mituyama T, Safran M, Lancet D.

Bioinformatics. 2013 Jan 15;29(2):255-61. doi: 10.1093/bioinformatics/bts676. Epub 2012 Nov 19.

PMID:
23172862
40.

Is there an optimal level of open-endedness in prebiotic evolution?

Markovitch O, Sorek D, Lui LT, Lancet D, Krasnogor N.

Orig Life Evol Biosph. 2012 Oct;42(5):469-73; discussion 474. doi: 10.1007/s11084-012-9309-y.

PMID:
23114973
41.

General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations.

Keydar I, Ben-Asher E, Feldmesser E, Nativ N, Oshimoto A, Restrepo D, Matsunami H, Chien MS, Pinto JM, Gilad Y, Olender T, Lancet D.

Hum Mutat. 2013 Jan;34(1):32-41. doi: 10.1002/humu.22212. Epub 2012 Oct 11.

42.

Personal receptor repertoires: olfaction as a model.

Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D.

BMC Genomics. 2012 Aug 21;13:414. doi: 10.1186/1471-2164-13-414.

43.

Evolutionary grass roots for odor recognition.

Olender T, Lancet D.

Chem Senses. 2012 Sep;37(7):581-4. doi: 10.1093/chemse/bjs054. Epub 2012 Jun 13.

PMID:
22695794
44.

Excess mutual catalysis is required for effective evolvability.

Markovitch O, Lancet D.

Artif Life. 2012 Summer;18(3):243-66. doi: 10.1162/artl_a_00064. Epub 2012 Jun 4.

PMID:
22662913
45.

Genome sequence of the pattern-forming social bacterium Paenibacillus dendritiformis C454 chiral morphotype.

Sirota-Madi A, Olender T, Helman Y, Brainis I, Finkelshtein A, Roth D, Hagai E, Leshkowitz D, Brodsky L, Galatenko V, Nikolaev V, Gutnick DL, Lancet D, Ben-Jacob E.

J Bacteriol. 2012 Apr;194(8):2127-8. doi: 10.1128/JB.00158-12.

46.

Association of the type 2 diabetes mellitus susceptibility gene, TCF7L2, with schizophrenia in an Arab-Israeli family sample.

Alkelai A, Greenbaum L, Lupoli S, Kohn Y, Sarner-Kanyas K, Ben-Asher E, Lancet D, Macciardi F, Lerer B.

PLoS One. 2012;7(1):e29228. doi: 10.1371/journal.pone.0029228. Epub 2012 Jan 11.

47.

In-silico human genomics with GeneCards.

Stelzer G, Dalah I, Stein TI, Satanower Y, Rosen N, Nativ N, Oz-Levi D, Olender T, Belinky F, Bahir I, Krug H, Perco P, Mayer B, Kolker E, Safran M, Lancet D.

Hum Genomics. 2011 Oct;5(6):709-17.

48.

MOPED: Model Organism Protein Expression Database.

Kolker E, Higdon R, Haynes W, Welch D, Broomall W, Lancet D, Stanberry L, Kolker N.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1093-9. doi: 10.1093/nar/gkr1177. Epub 2011 Dec 1.

49.

Replication of simulated prebiotic amphiphile vesicles controlled by experimental lipid physicochemical properties.

Armstrong DL, Markovitch O, Zidovetzki R, Lancet D.

Phys Biol. 2011 Dec;8(6):066001. doi: 10.1088/1478-3975/8/6/066001. Epub 2011 Sep 26.

PMID:
21946049
50.

Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample.

Alkelai A, Lupoli S, Greenbaum L, Giegling I, Kohn Y, Sarner-Kanyas K, Ben-Asher E, Lancet D, Rujescu D, Macciardi F, Lerer B.

FASEB J. 2011 Nov;25(11):4011-23. doi: 10.1096/fj.11-184937. Epub 2011 Jul 27.

PMID:
21795503

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