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Items: 40


Disease modelling in human organoids.

Lancaster MA, Huch M.

Dis Model Mech. 2019 Jul 29;12(7). pii: dmm039347. doi: 10.1242/dmm.039347. Review.


Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output.

Giandomenico SL, Mierau SB, Gibbons GM, Wenger LMD, Masullo L, Sit T, Sutcliffe M, Boulanger J, Tripodi M, Derivery E, Paulsen O, Lakatos A, Lancaster MA.

Nat Neurosci. 2019 Apr;22(4):669-679. doi: 10.1038/s41593-019-0350-2. Epub 2019 Mar 18.


An Electric Take on Neural Fate and Cortical Development.

Lancaster MA.

Dev Cell. 2019 Jan 7;48(1):1-2. doi: 10.1016/j.devcel.2018.12.014.


Author Correction: Comprehensive comparative analysis of 5'-end RNA-sequencing methods.

Adiconis X, Haber AL, Simmons SK, Moonshine AL, Ji Z, Busby MA, Shi X, Jacques J, Lancaster MA, Pan JQ, Regev A, Levin JZ.

Nat Methods. 2018 Dec;15(12):1126. doi: 10.1038/s41592-018-0237-2.


Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids.

Lancaster MA, Corsini NS, Wolfinger S, Gustafson EH, Phillips AW, Burkard TR, Otani T, Livesey FJ, Knoblich JA.

Nat Biotechnol. 2018 Oct 11;36(10):1016. doi: 10.1038/nbt1018-1016a.


Chronic differences in white matter integrity following sport-related concussion as measured by diffusion MRI: 6-Month follow-up.

Lancaster MA, Meier TB, Olson DV, McCrea MA, Nelson LD, Muftuler LT.

Hum Brain Mapp. 2018 Nov;39(11):4276-4289. doi: 10.1002/hbm.24245. Epub 2018 Jul 2.


Comprehensive comparative analysis of 5'-end RNA-sequencing methods.

Adiconis X, Haber AL, Simmons SK, Levy Moonshine A, Ji Z, Busby MA, Shi X, Jacques J, Lancaster MA, Pan JQ, Regev A, Levin JZ.

Nat Methods. 2018 Jul;15(7):505-511. doi: 10.1038/s41592-018-0014-2. Epub 2018 Jun 4. Erratum in: Nat Methods. 2018 Dec;15(12):1126.


Brain organoids get vascularized.

Lancaster MA.

Nat Biotechnol. 2018 May 9;36(5):407-408. doi: 10.1038/nbt.4133. No abstract available.


Crinkle-Cut Brain Organoids.

Lancaster MA.

Cell Stem Cell. 2018 May 3;22(5):616-618. doi: 10.1016/j.stem.2018.04.011.


Understanding the role of steroids in typical and atypical brain development: Advantages of using a "brain in a dish" approach.

Adhya D, Annuario E, Lancaster MA, Price J, Baron-Cohen S, Srivastava DP.

J Neuroendocrinol. 2018 Feb;30(2). doi: 10.1111/jne.12547. Review.


Non-model model organisms.

Russell JJ, Theriot JA, Sood P, Marshall WF, Landweber LF, Fritz-Laylin L, Polka JK, Oliferenko S, Gerbich T, Gladfelter A, Umen J, Bezanilla M, Lancaster MA, He S, Gibson MC, Goldstein B, Tanaka EM, Hu CK, Brunet A.

BMC Biol. 2017 Jun 29;15(1):55. doi: 10.1186/s12915-017-0391-5.


Guided self-organization and cortical plate formation in human brain organoids.

Lancaster MA, Corsini NS, Wolfinger S, Gustafson EH, Phillips AW, Burkard TR, Otani T, Livesey FJ, Knoblich JA.

Nat Biotechnol. 2017 Jul;35(7):659-666. doi: 10.1038/nbt.3906. Epub 2017 May 31. Erratum in: Nat Biotechnol. 2018 Oct 11;36(10):1016.


A Simple Method of Generating 3D Brain Organoids Using Standard Laboratory Equipment.

Sutcliffe M, Lancaster MA.

Methods Mol Biol. 2019;1576:1-12. doi: 10.1007/7651_2017_2.


Self-organized developmental patterning and differentiation in cerebral organoids.

Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA.

EMBO J. 2017 May 15;36(10):1316-1329. doi: 10.15252/embj.201694700. Epub 2017 Mar 10.


Probing human brain evolution and development in organoids.

Giandomenico SL, Lancaster MA.

Curr Opin Cell Biol. 2017 Feb;44:36-43. doi: 10.1016/ Epub 2017 Jan 31. Review.


Induction of Expansion and Folding in Human Cerebral Organoids.

Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R.

Cell Stem Cell. 2017 Mar 2;20(3):385-396.e3. doi: 10.1016/j.stem.2016.11.017. Epub 2016 Dec 29.


Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain.

Luo C, Lancaster MA, Castanon R, Nery JR, Knoblich JA, Ecker JR.

Cell Rep. 2016 Dec 20;17(12):3369-3384. doi: 10.1016/j.celrep.2016.12.001.


Diffusion Tensor Imaging Predictors of Episodic Memory Decline in Healthy Elders at Genetic Risk for Alzheimer's Disease.

Lancaster MA, Seidenberg M, Smith JC, Nielson KA, Woodard JL, Durgerian S, Rao SM.

J Int Neuropsychol Soc. 2016 Nov;22(10):1005-1015.


Abnormalities in Functional Connectivity in Collegiate Football Athletes with and without a Concussion History: Implications and Role of Neuroactive Kynurenine Pathway Metabolites.

Meier TB, Lancaster MA, Mayer AR, Teague TK, Savitz J.

J Neurotrauma. 2017 Feb 15;34(4):824-837. doi: 10.1089/neu.2016.4599. Epub 2016 Oct 13.


Dishing out mini-brains: Current progress and future prospects in brain organoid research.

Kelava I, Lancaster MA.

Dev Biol. 2016 Dec 15;420(2):199-209. doi: 10.1016/j.ydbio.2016.06.037. Epub 2016 Jul 9. Review.


Stem Cell Models of Human Brain Development.

Kelava I, Lancaster MA.

Cell Stem Cell. 2016 Jun 2;18(6):736-48. doi: 10.1016/j.stem.2016.05.022. Review.


Acute white matter changes following sport-related concussion: A serial diffusion tensor and diffusion kurtosis tensor imaging study.

Lancaster MA, Olson DV, McCrea MA, Nelson LD, LaRoche AA, Muftuler LT.

Hum Brain Mapp. 2016 Nov;37(11):3821-3834. doi: 10.1002/hbm.23278.


Psychometric properties and normative data for the Brief Symptom Inventory-18 (BSI-18) in high school and collegiate athletes.

Lancaster MA, McCrea MA, Nelson LD.

Clin Neuropsychol. 2016 Feb;30(2):338-50. doi: 10.1080/13854046.2016.1138504. Epub 2016 Feb 29.


Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.

Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R.

Stem Cell Reports. 2015 Dec 8;5(6):933-945. doi: 10.1016/j.stemcr.2015.10.011. Epub 2015 Nov 21.


Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders.

Smith JC, Lancaster MA, Nielson KA, Woodard JL, Seidenberg M, Durgerian S, Sakaie K, Rao SM.

Neuroimage. 2016 May 1;131:102-12. doi: 10.1016/j.neuroimage.2015.08.007. Epub 2015 Aug 8.


Generation of cerebral organoids from human pluripotent stem cells.

Lancaster MA, Knoblich JA.

Nat Protoc. 2014 Oct;9(10):2329-40. doi: 10.1038/nprot.2014.158. Epub 2014 Sep 4.


Organogenesis in a dish: modeling development and disease using organoid technologies.

Lancaster MA, Knoblich JA.

Science. 2014 Jul 18;345(6194):1247125. doi: 10.1126/science.1247125. Epub 2014 Jul 17. Review.


Cerebral organoids model human brain development and microcephaly.

Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, Hurles ME, Homfray T, Penninger JM, Jackson AP, Knoblich JA.

Nature. 2013 Sep 19;501(7467):373-9. doi: 10.1038/nature12517. Epub 2013 Aug 28.


Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion.

David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Munafò MR, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R.

Addiction. 2013 Dec;108(12):2202-11. doi: 10.1111/add.12325. Epub 2013 Sep 18.


Spindle orientation in mammalian cerebral cortical development.

Lancaster MA, Knoblich JA.

Curr Opin Neurobiol. 2012 Oct;22(5):737-46. doi: 10.1016/j.conb.2012.04.003. Epub 2012 May 2. Review.


Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome.

Lancaster MA, Gopal DJ, Kim J, Saleem SN, Silhavy JL, Louie CM, Thacker BE, Williams Y, Zaki MS, Gleeson JG.

Nat Med. 2011 Jun;17(6):726-31. doi: 10.1038/nm.2380. Epub 2011 May 29.


Subcellular spatial regulation of canonical Wnt signalling at the primary cilium.

Lancaster MA, Schroth J, Gleeson JG.

Nat Cell Biol. 2011 Jun;13(6):700-7. doi: 10.1038/ncb2259. Epub 2011 May 22.


Does physical activity influence semantic memory activation in amnestic mild cognitive impairment?

Smith JC, Nielson KA, Woodard JL, Seidenberg M, Verber MD, Durgerian S, Antuono P, Butts AM, Hantke NC, Lancaster MA, Rao SM.

Psychiatry Res. 2011 Jul 30;193(1):60-2. doi: 10.1016/j.pscychresns.2011.04.001. Epub 2011 May 23.


Interactive effects of physical activity and APOE-ε4 on BOLD semantic memory activation in healthy elders.

Smith JC, Nielson KA, Woodard JL, Seidenberg M, Durgerian S, Antuono P, Butts AM, Hantke NC, Lancaster MA, Rao SM.

Neuroimage. 2011 Jan 1;54(1):635-44. doi: 10.1016/j.neuroimage.2010.07.070. Epub 2010 Aug 5.


Cystic kidney disease: the role of Wnt signaling.

Lancaster MA, Gleeson JG.

Trends Mol Med. 2010 Aug;16(8):349-60. doi: 10.1016/j.molmed.2010.05.004. Epub 2010 Jun 22. Review.


AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis.

Louie CM, Caridi G, Lopes VS, Brancati F, Kispert A, Lancaster MA, Schlossman AM, Otto EA, Leitges M, Gröne HJ, Lopez I, Gudiseva HV, O'Toole JF, Vallespin E, Ayyagari R, Ayuso C, Cremers FP, den Hollander AI, Koenekoop RK, Dallapiccola B, Ghiggeri GM, Hildebrandt F, Valente EM, Williams DS, Gleeson JG.

Nat Genet. 2010 Feb;42(2):175-80. doi: 10.1038/ng.519. Epub 2010 Jan 17.


Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy.

Lancaster MA, Louie CM, Silhavy JL, Sintasath L, Decambre M, Nigam SK, Willert K, Gleeson JG.

Nat Med. 2009 Sep;15(9):1046-54. doi: 10.1038/nm.2010. Epub 2009 Aug 30.


The primary cilium as a cellular signaling center: lessons from disease.

Lancaster MA, Gleeson JG.

Curr Opin Genet Dev. 2009 Jun;19(3):220-9. doi: 10.1016/j.gde.2009.04.008. Epub 2009 May 22. Review.


Mutations in CEP290, which encodes a centrosomal protein, cause pleiotropic forms of Joubert syndrome.

Valente EM, Silhavy JL, Brancati F, Barrano G, Krishnaswami SR, Castori M, Lancaster MA, Boltshauser E, Boccone L, Al-Gazali L, Fazzi E, Signorini S, Louie CM, Bellacchio E; International Joubert Syndrome Related Disorders Study Group, Bertini E, Dallapiccola B, Gleeson JG.

Nat Genet. 2006 Jun;38(6):623-5. Epub 2006 May 7.


A child with earache.

Lancaster MA.

Aust Fam Physician. 2002 May;31(5):410; author reply 410-1. No abstract available.


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