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Items: 1 to 50 of 57

1.

Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease.

Paul S, Lancaster GI, Meikle PJ.

Prog Lipid Res. 2019 Apr;74:186-195. doi: 10.1016/j.plipres.2019.04.003. Epub 2019 Apr 8. Review.

PMID:
30974122
2.

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.

Dragoljevic D, Kraakman MJ, Nagareddy PR, Ngo D, Shihata W, Kammoun HL, Whillas A, Lee MKS, Al-Sharea A, Pernes G, Flynn MC, Lancaster GI, Febbraio MA, Chin-Dusting J, Hanaoka BY, Wicks IP, Murphy AJ.

Eur Heart J. 2018 Jun 14;39(23):2158-2167. doi: 10.1093/eurheartj/ehy119.

3.

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice.

Lancaster GI, Henstridge DC.

J Vis Exp. 2018 May 24;(135). doi: 10.3791/57280.

PMID:
29889190
4.

Lipidomic Profiling of Murine Macrophages Treated with Fatty Acids of Varying Chain Length and Saturation Status.

Huynh K, Pernes G, Mellett NA, Meikle PJ, Murphy AJ, Lancaster GI.

Metabolites. 2018 Apr 23;8(2). pii: E29. doi: 10.3390/metabo8020029.

5.

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism.

Lancaster GI, Langley KG, Berglund NA, Kammoun HL, Reibe S, Estevez E, Weir J, Mellett NA, Pernes G, Conway JRW, Lee MKS, Timpson P, Murphy AJ, Masters SL, Gerondakis S, Bartonicek N, Kaczorowski DC, Dinger ME, Meikle PJ, Bond PJ, Febbraio MA.

Cell Metab. 2018 May 1;27(5):1096-1110.e5. doi: 10.1016/j.cmet.2018.03.014. Epub 2018 Apr 19.

6.

Evidence against a role for NLRP3-driven islet inflammation in db/db mice.

Kammoun HL, Allen TL, Henstridge DC, Barre S, Coll RC, Lancaster GI, Cron L, Reibe S, Chan JY, Bensellam M, Laybutt DR, Butler MS, Robertson AAB, O'Neill LA, Cooper MA, Febbraio MA.

Mol Metab. 2018 Apr;10:66-73. doi: 10.1016/j.molmet.2018.02.001. Epub 2018 Feb 7.

7.

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.

Kraakman MJ, Kammoun HL, Dragoljevic D, Al-Sharea A, Lee MKS, Flynn MC, Stolz CJ, Guirguis AA, Lancaster GI, Chin-Dusting J, Curtis DJ, Murphy AJ.

Haematologica. 2018 Apr;103(4):597-606. doi: 10.3324/haematol.2017.181958. Epub 2018 Jan 25.

8.

Take me to the liver: adipose tissue macrophages coordinate hepatic neutrophil recruitment.

Pernes G, Lancaster GI, Murphy AJ.

Gut. 2018 Jul;67(7):1204-1206. doi: 10.1136/gutjnl-2017-315393. Epub 2018 Jan 3. No abstract available.

PMID:
29298875
9.

Single-Payer Reform.

Lancaster GI, Drozda JP Jr.

Ann Intern Med. 2017 Oct 3;167(7):526-527. doi: 10.7326/L17-0324. No abstract available.

PMID:
28973205
10.

Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism.

Chaurasia B, Kaddai VA, Lancaster GI, Henstridge DC, Sriram S, Galam DL, Gopalan V, Prakash KN, Velan SS, Bulchand S, Tsong TJ, Wang M, Siddique MM, Yuguang G, Sigmundsson K, Mellet NA, Weir JM, Meikle PJ, Bin M Yassin MS, Shabbir A, Shayman JA, Hirabayashi Y, Shiow ST, Sugii S, Summers SA.

Cell Metab. 2016 Dec 13;24(6):820-834. doi: 10.1016/j.cmet.2016.10.002. Epub 2016 Nov 3.

11.

PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications.

Lancaster GI, Kammoun HL, Kraakman MJ, Kowalski GM, Bruce CR, Febbraio MA.

Nat Commun. 2016 Feb 3;7:10626. doi: 10.1038/ncomms10626.

12.

Exercise and the immune system: implications for elite athletes and the general population.

Lancaster GI, Febbraio MA.

Immunol Cell Biol. 2016 Feb;94(2):115-6. doi: 10.1038/icb.2015.103. Epub 2015 Dec 15. No abstract available.

PMID:
26667594
13.

The roles of c-Jun NH2-terminal kinases (JNKs) in obesity and insulin resistance.

Pal M, Febbraio MA, Lancaster GI.

J Physiol. 2016 Jan 15;594(2):267-79. doi: 10.1113/JP271457. Epub 2015 Dec 14. Review.

14.

Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism.

Meex RC, Hoy AJ, Morris A, Brown RD, Lo JC, Burke M, Goode RJ, Kingwell BA, Kraakman MJ, Febbraio MA, Greve JW, Rensen SS, Molloy MP, Lancaster GI, Bruce CR, Watt MJ.

Cell Metab. 2015 Dec 1;22(6):1078-89. doi: 10.1016/j.cmet.2015.09.023. Epub 2015 Oct 22.

15.

Blocking IL-6 trans-signaling prevents high-fat diet-induced adipose tissue macrophage recruitment but does not improve insulin resistance.

Kraakman MJ, Kammoun HL, Allen TL, Deswaerte V, Henstridge DC, Estevez E, Matthews VB, Neill B, White DA, Murphy AJ, Peijs L, Yang C, Risis S, Bruce CR, Du XJ, Bobik A, Lee-Young RS, Kingwell BA, Vasanthakumar A, Shi W, Kallies A, Lancaster GI, Rose-John S, Febbraio MA.

Cell Metab. 2015 Mar 3;21(3):403-16. doi: 10.1016/j.cmet.2015.02.006. Erratum in: Cell Metab. 2016 Mar 8;23(3):563.

16.

The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice.

Lancaster GI, Kraakman MJ, Kammoun HL, Langley KG, Estevez E, Banerjee A, Grumont RJ, Febbraio MA, Gerondakis S.

PLoS One. 2014 Nov 6;9(11):e111524. doi: 10.1371/journal.pone.0111524. eCollection 2014.

17.

Endogenous, adipocyte-derived lipids signal the recruitment of proinflammatory immune cells.

Lancaster GI, Langley KG.

Diabetes. 2014 Jun;63(6):1844-6. doi: 10.2337/db14-0303. No abstract available.

18.

The immunomodulating role of exercise in metabolic disease.

Lancaster GI, Febbraio MA.

Trends Immunol. 2014 Jun;35(6):262-9. doi: 10.1016/j.it.2014.02.008. Epub 2014 Mar 26. Review.

PMID:
24680647
19.

Targeting gp130 to prevent inflammation and promote insulin action.

Kraakman MJ, Allen TL, Whitham M, Iliades P, Kammoun HL, Estevez E, Lancaster GI, Febbraio MA.

Diabetes Obes Metab. 2013 Sep;15 Suppl 3:170-5. doi: 10.1111/dom.12170. Review.

PMID:
24003934
20.

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding.

Turner N, Kowalski GM, Leslie SJ, Risis S, Yang C, Lee-Young RS, Babb JR, Meikle PJ, Lancaster GI, Henstridge DC, White PJ, Kraegen EW, Marette A, Cooney GJ, Febbraio MA, Bruce CR.

Diabetologia. 2013 Jul;56(7):1638-48. doi: 10.1007/s00125-013-2913-1. Epub 2013 Apr 26.

PMID:
23620060
21.

Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice.

Henstridge DC, Bruce CR, Pang CP, Lancaster GI, Allen TL, Estevez E, Gardner T, Weir JM, Meikle PJ, Lam KSL, Xu A, Fujii N, Goodyear LJ, Febbraio MA.

Diabetologia. 2012 Oct;55(10):2769-2778. doi: 10.1007/s00125-012-2652-8. Epub 2012 Jul 26.

22.

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin.

Winbanks CE, Weeks KL, Thomson RE, Sepulveda PV, Beyer C, Qian H, Chen JL, Allen JM, Lancaster GI, Febbraio MA, Harrison CA, McMullen JR, Chamberlain JS, Gregorevic P.

J Cell Biol. 2012 Jun 25;197(7):997-1008. doi: 10.1083/jcb.201109091. Epub 2012 Jun 18.

23.

Tumor progression locus 2 (Tpl2) deficiency does not protect against obesity-induced metabolic disease.

Lancaster GI, Kowalski GM, Estevez E, Kraakman MJ, Grigoriadis G, Febbraio MA, Gerondakis S, Banerjee A.

PLoS One. 2012;7(6):e39100. doi: 10.1371/journal.pone.0039100. Epub 2012 Jun 11.

24.

IκB kinase β (IKKβ) does not mediate feedback inhibition of the insulin signalling cascade.

Lancaster GI, Skiba B, Yang C, Nicholls HT, Langley KG, Chan MH, Bruce CR, Rewcastle GW, Shepherd PR, Karin M, Febbraio MA.

Biochem J. 2012 Mar 15;442(3):723-32. doi: 10.1042/BJ20112037. Erratum in: Biochem J. 2013 May 15;452(1):171.

PMID:
22364283
25.

Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1.

Whitham M, Chan MH, Pal M, Matthews VB, Prelovsek O, Lunke S, El-Osta A, Broenneke H, Alber J, Brüning JC, Wunderlich FT, Lancaster GI, Febbraio MA.

J Biol Chem. 2012 Mar 30;287(14):10771-9. doi: 10.1074/jbc.M111.310581. Epub 2012 Feb 18.

26.

Previous aspirin use in acute coronary syndromes: more than a marker?

Lancaster GI, Srivastava AV, Zarich SW.

J Am Coll Cardiol. 2011 Apr 19;57(16):1715; author reply 1715-6. doi: 10.1016/j.jacc.2010.11.042. No abstract available.

27.

Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue.

Nicholls HT, Kowalski G, Kennedy DJ, Risis S, Zaffino LA, Watson N, Kanellakis P, Watt MJ, Bobik A, Bonen A, Febbraio M, Lancaster GI, Febbraio MA.

Diabetes. 2011 Apr;60(4):1100-10. doi: 10.2337/db10-1353. Epub 2011 Mar 4.

28.

A proteomic analysis of C-reactive protein stimulated THP-1 monocytes.

Eisenhardt SU, Habersberger J, Oliva K, Lancaster GI, Ayhan M, Woollard KJ, Bannasch H, Rice GE, Peter K.

Proteome Sci. 2011 Jan 10;9(1):1. doi: 10.1186/1477-5956-9-1.

29.

Adiponectin sphings into action.

Lancaster GI, Febbraio MA.

Nat Med. 2011 Jan;17(1):37-8. doi: 10.1038/nm0111-37. No abstract available.

PMID:
21217676
30.

Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice.

Kowalski GM, Nicholls HT, Risis S, Watson NK, Kanellakis P, Bruce CR, Bobik A, Lancaster GI, Febbraio MA.

Diabetologia. 2011 Apr;54(4):888-99. doi: 10.1007/s00125-010-2020-5. Epub 2011 Jan 6.

PMID:
21210076
31.

Contraction-induced changes in TNFalpha and Akt-mediated signalling are associated with increased myofibrillar protein in rat skeletal muscle.

Karagounis LG, Yaspelkis BB 3rd, Reeder DW, Lancaster GI, Hawley JA, Coffey VG.

Eur J Appl Physiol. 2010 Jul;109(5):839-48. doi: 10.1007/s00421-010-1427-5. Epub 2010 Mar 13.

PMID:
20229019
32.

Letter by Lancaster et al regarding article, "Tissue Doppler imaging in the estimation of intracardiac filling pressure in decompensated patients with advanced systolic heart failure".

Lancaster GI, Srinivasan J, Jain H.

Circulation. 2009 Aug 18;120(7):e48. doi: 10.1161/CIRCULATIONAHA.109.858423. No abstract available.

PMID:
19687367
33.

The expanding medical and behavioral resources with access to care for everyone health plan.

Lancaster GI, O'Connell R, Katz DL, Manson JE, Hutchison WR, Landau C, Yonkers KA; Healthcare Professionals for Healthcare Reform.

Ann Intern Med. 2009 Apr 7;150(7):490-2. Epub 2009 Mar 2.

PMID:
19258548
34.

Aspirin resistance: an update.

Lancaster GI, Srinivasan J, Jain H.

Curr Atheroscler Rep. 2009 Mar;11(2):105-10. Review.

PMID:
19228483
35.

Skeletal muscle: not simply an organ for locomotion and energy storage.

Lancaster GI, Febbraio MA.

J Physiol. 2009 Feb 1;587(3):509-10. doi: 10.1113/jphysiol.2008.165753. Epub 2008 Dec 1. No abstract available.

36.

Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats.

Holmes AG, Mesa JL, Neill BA, Chung J, Carey AL, Steinberg GR, Kemp BE, Southgate RJ, Lancaster GI, Bruce CR, Watt MJ, Febbraio MA.

J Endocrinol. 2008 Aug;198(2):367-74. doi: 10.1677/JOE-08-0113. Epub 2008 Jun 3. Erratum in: J Endocrinol. 2008 Oct;199(1):147.

PMID:
18523033
37.

Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes.

Soro-Paavonen A, Watson AM, Li J, Paavonen K, Koitka A, Calkin AC, Barit D, Coughlan MT, Drew BG, Lancaster GI, Thomas M, Forbes JM, Nawroth PP, Bierhaus A, Cooper ME, Jandeleit-Dahm KA.

Diabetes. 2008 Sep;57(9):2461-9. doi: 10.2337/db07-1808. Epub 2008 May 28.

38.

Survey of Connecticut cardiologists on health-care reform.

Lancaster GI, Schoenfeld MH.

Conn Med. 2008 Apr;72(4):211-3. No abstract available.

PMID:
18478987
39.

HSP72 protects against obesity-induced insulin resistance.

Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1739-44. doi: 10.1073/pnas.0705799105. Epub 2008 Jan 25.

40.

Effect of high-frequency resistance exercise on adaptive responses in skeletal muscle.

Coffey VG, Reeder DW, Lancaster GI, Yeo WK, Febbraio MA, Yaspelkis BB 3rd, Hawley JA.

Med Sci Sports Exerc. 2007 Dec;39(12):2135-44.

PMID:
18046184
41.

The role of aspirin resistance in the treatment of acute coronary syndromes.

Lancaster GI, Jain H, Zarich SW.

Clin Cardiol. 2008 Jan;31(1):11-7. Review.

42.

Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance.

Turpin SM, Lancaster GI, Darby I, Febbraio MA, Watt MJ.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1341-50. Epub 2006 Jul 18.

43.
44.
45.

Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins.

Lancaster GI, Febbraio MA.

J Biol Chem. 2005 Jun 17;280(24):23349-55. Epub 2005 Apr 12.

46.

The physiological regulation of toll-like receptor expression and function in humans.

Lancaster GI, Khan Q, Drysdale P, Wallace F, Jeukendrup AE, Drayson MT, Gleeson M.

J Physiol. 2005 Mar 15;563(Pt 3):945-55. Epub 2005 Jan 20.

47.

Effects of acute exhaustive exercise and chronic exercise training on type 1 and type 2 T lymphocytes.

Lancaster GI, Halson SL, Khan Q, Drysdale P, Wallace F, Jeukendrup AE, Drayson MT, Gleeson M.

Exerc Immunol Rev. 2004;10:91-106.

48.

Exercise induces the release of heat shock protein 72 from the human brain in vivo.

Lancaster GI, Møller K, Nielsen B, Secher NH, Febbraio MA, Nybo L.

Cell Stress Chaperones. 2004 Autumn;9(3):276-80.

49.

Leukocyte heat shock protein expression before and after intensified training.

Whitham M, Halson SL, Lancaster GI, Gleeson M, Jeukendrup AE, Blannin AK.

Int J Sports Med. 2004 Oct;25(7):522-7.

PMID:
15459833
50.

Effect of prolonged exercise and carbohydrate ingestion on type 1 and type 2 T lymphocyte distribution and intracellular cytokine production in humans.

Lancaster GI, Khan Q, Drysdale PT, Wallace F, Jeukendrup AE, Drayson MT, Gleeson M.

J Appl Physiol (1985). 2005 Feb;98(2):565-71. Epub 2004 Aug 20.

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