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Items: 1 to 50 of 111

1.

Obesity Causes Renal Mitochondrial Dysfunction and Energy Imbalance and Accelerates Chronic Kidney Disease in Mice.

Andres-Hernando A, Lanaspa MA, Kuwabara M, Orlicky DJ, Cicerchi C, Bales E, Garcia GE, Roncal-Jimenez CA, Sato Y, Johnson RJ.

Am J Physiol Renal Physiol. 2019 Aug 14. doi: 10.1152/ajprenal.00203.2019. [Epub ahead of print]

PMID:
31411075
2.

The increase of core temperature affected the progression of kidney injury by repeated heat stress exposure.

Sato Y, Roncal-Jimenez CA, Andres-Hernando A, Jensen T, Tolan DR, Sanchez-Lozada LG, Newman LS, Butler-Dawson J, Sorensen C, Glaser J, Miyazaki M, Diaz HF, Ishimoto T, Kosugi T, Maruyama S, Garcia GE, Lanaspa MA, Johnson RJ.

Am J Physiol Renal Physiol. 2019 Aug 7. doi: 10.1152/ajprenal.00259.2019. [Epub ahead of print]

PMID:
31390229
3.

Antidiuretic hormone and serum osmolarity physiology and related outcomes: What is old, what is new and what is unknown?

Kanbay M, Yilmaz S, Dincer N, Ortiz A, Sag AA, Covic A, Sánchez-Lozada LG, Lanaspa MA, Cherney DZI, Johnson RJ, Afsar B.

J Clin Endocrinol Metab. 2019 Jul 31. pii: jc.2019-01049. doi: 10.1210/jc.2019-01049. [Epub ahead of print]

PMID:
31365096
4.

The case for uric acid-lowering treatment in patients with hyperuricaemia and CKD.

Sato Y, Feig DI, Stack AG, Kang DH, Lanaspa MA, Ejaz AA, Sánchez-Lozada LG, Kuwabara M, Borghi C, Johnson RJ.

Nat Rev Nephrol. 2019 Jul 11. doi: 10.1038/s41581-019-0174-z. [Epub ahead of print] Review.

PMID:
31296965
5.

Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase.

Hayasaki T, Ishimoto T, Doke T, Hirayama A, Soga T, Furuhashi K, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Maruyama S, Kadomatsu K.

J Nutr Biochem. 2019 Jun 8;71:54-62. doi: 10.1016/j.jnutbio.2019.05.017. [Epub ahead of print]

PMID:
31276916
6.

Climate Change and the Kidney.

Johnson RJ, Sánchez-Lozada LG, Newman LS, Lanaspa MA, Diaz HF, Lemery J, Rodriguez-Iturbe B, Tolan DR, Butler-Dawson J, Sato Y, Garcia G, Hernando AA, Roncal-Jimenez CA.

Ann Nutr Metab. 2019;74 Suppl 3:38-44. doi: 10.1159/000500344. Epub 2019 Jun 14.

7.

Endogenous fructose production: what do we know and how relevant is it?

Andres-Hernando A, Johnson RJ, Lanaspa MA.

Curr Opin Clin Nutr Metab Care. 2019 Jul;22(4):289-294. doi: 10.1097/MCO.0000000000000573.

PMID:
31166222
8.

Are Liquid Sugars Different from Solid Sugar in Their Ability to Cause Metabolic Syndrome?

Sundborn G, Thornley S, Merriman TR, Lang B, King C, Lanaspa MA, Johnson RJ.

Obesity (Silver Spring). 2019 Jun;27(6):879-887. doi: 10.1002/oby.22472. Epub 2019 May 4. Review.

PMID:
31054268
9.

The effects of fruit consumption in patients with hyperuricaemia or gout.

Nakagawa T, Lanaspa MA, Johnson RJ.

Rheumatology (Oxford). 2019 Jul 1;58(7):1133-1141. doi: 10.1093/rheumatology/kez128.

PMID:
31004140
10.

The perils of rehydrating with soft drinks following heat and exercise.

Sánchez-Lozada LG, Roncal-Jimenez CA, García-Arroyo FE, Jensen T, Lanaspa MA, Johnson RJ.

Am J Physiol Regul Integr Comp Physiol. 2019 Mar 1;316(3):R187-R188. doi: 10.1152/ajpregu.00007.2019. Epub 2019 Jan 23. No abstract available.

PMID:
30673300
11.

Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats.

Sanchez-Lozada LG, Andres-Hernando A, Garcia-Arroyo FE, Cicerchi C, Li N, Kuwabara M, Roncal-Jimenez CA, Johnson RJ, Lanaspa MA.

J Biol Chem. 2019 Mar 15;294(11):4272-4281. doi: 10.1074/jbc.RA118.006158. Epub 2019 Jan 16.

PMID:
30651350
12.

Multilayered Interplay Between Fructose and Salt in Development of Hypertension.

Eren OC, Ortiz A, Afsar B, Covic A, Kuwabara M, Lanaspa MA, Johnson RJ, Kanbay M.

Hypertension. 2019 Feb;73(2):265-272. doi: 10.1161/HYPERTENSIONAHA.118.12150. No abstract available.

PMID:
30595116
13.

Fasting blood glucose is predictive of hypertension in a general Japanese population.

Kuwabara M, Chintaluru Y, Kanbay M, Niwa K, Hisatome I, Andres-Hernando A, Roncal-Jimenez C, Ohno M, Johnson RJ, Lanaspa MA.

J Hypertens. 2019 Jan;37(1):167-174. doi: 10.1097/HJH.0000000000001895.

PMID:
30507865
14.

Fructose increases risk for kidney stones: potential role in metabolic syndrome and heat stress.

Johnson RJ, Perez-Pozo SE, Lillo JL, Grases F, Schold JD, Kuwabara M, Sato Y, Hernando AA, Garcia G, Jensen T, Rivard C, Sanchez-Lozada LG, Roncal C, Lanaspa MA.

BMC Nephrol. 2018 Nov 8;19(1):315. doi: 10.1186/s12882-018-1105-0.

15.

Acute effects of salt on blood pressure are mediated by serum osmolality.

Kanbay M, Aslan G, Afsar B, Dagel T, Siriopol D, Kuwabara M, Incir S, Camkiran V, Rodriguez-Iturbe B, Lanaspa MA, Covic A, Johnson RJ.

J Clin Hypertens (Greenwich). 2018 Oct;20(10):1447-1454. doi: 10.1111/jch.13374. Epub 2018 Sep 19.

16.

Increased Serum Uric Acid over five years is a Risk Factor for Developing Fatty Liver.

Jensen T, Niwa K, Hisatome I, Kanbay M, Andres-Hernando A, Roncal-Jimenez CA, Sato Y, Garcia G, Ohno M, Lanaspa MA, Johnson RJ, Kuwabara M.

Sci Rep. 2018 Aug 6;8(1):11735. doi: 10.1038/s41598-018-30267-2.

17.

Different Risk for Hypertension, Diabetes, Dyslipidemia, and Hyperuricemia According to Level of Body Mass Index in Japanese and American Subjects.

Kuwabara M, Kuwabara R, Niwa K, Hisatome I, Smits G, Roncal-Jimenez CA, MacLean PS, Yracheta JM, Ohno M, Lanaspa MA, Johnson RJ, Jalal DI.

Nutrients. 2018 Aug 3;10(8). pii: E1011. doi: 10.3390/nu10081011.

18.

Rehydration with fructose worsens dehydration-induced renal damage.

Milagres T, García-Arroyo FE, Lanaspa MA, Garcia G, Ishimoto T, Andres-Hernando A, Kuwabara M, Jensen T, Sato Y, Glaser J, Sánchez-Lozada LG, Johnson RJ, Roncal-Jimenez C.

BMC Nephrol. 2018 Jul 13;19(1):180. doi: 10.1186/s12882-018-0963-9.

19.

Correction: Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort Study.

Kuwabara M, Hisatome I, Roncal-Jimenez CA, Niwa K, Andres-Hernando A, Jensen T, Bjornstad P, Milagres T, Cicerchi C, Song Z, Garcia G, Sánchez-Lozada LG, Ohno M, Lanaspa MA, Johnson RJ.

PLoS One. 2018 May 17;13(5):e0197941. doi: 10.1371/journal.pone.0197941. eCollection 2018.

20.

Upregulation of CD80 on glomerular podocytes plays an important role in development of proteinuria following pig-to-baboon xeno-renal transplantation - an experimental study.

Rivard CJ, Tanabe T, Lanaspa MA, Watanabe H, Nomura S, Andres-Hernando A, Garth K, Sekijima M, Ishimoto T, Ariyoshi Y, Garcia GE, Shah J, Lennan B, Tasaki M, Pomposelli T, Shimizu A, Sachs DH, Johnson RJ, Yamada K.

Transpl Int. 2018 Oct;31(10):1164-1177. doi: 10.1111/tri.13273. Epub 2018 Jun 5.

21.

Different effects of global osteopontin and macrophage osteopontin in glomerular injury.

Trostel J, Truong LD, Roncal-Jimenez C, Miyazaki M, Miyazaki-Anzai S, Kuwabara M, McMahan R, Andres-Hernando A, Sato Y, Jensen T, Lanaspa MA, Johnson RJ, Garcia GE.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F759-F768. doi: 10.1152/ajprenal.00458.2017. Epub 2018 May 2.

PMID:
29717936
22.

Remaining Physiological Barriers in Porcine Kidney Xenotransplantation: Potential Pathways behind Proteinuria as well as Factors Related to Growth Discrepancies following Pig-to-Kidney Xenotransplantation.

Shah JA, Lanaspa MA, Tanabe T, Watanabe H, Johnson RJ, Yamada K.

J Immunol Res. 2018 Mar 4;2018:6413012. doi: 10.1155/2018/6413012. eCollection 2018. Review.

23.

The role of autoimmune reactivity induced by heat shock protein 70 in the pathogenesis of essential hypertension.

Rodriguez-Iturbe B, Lanaspa MA, Johnson RJ.

Br J Pharmacol. 2019 Jun;176(12):1829-1838. doi: 10.1111/bph.14334. Epub 2018 May 22. Review.

PMID:
29679484
24.

Experimental heat stress nephropathy and liver injury are improved by allopurinol.

Roncal-Jimenez CA, Sato Y, Milagres T, Andres Hernando A, García G, Bjornstad P, Dawson JB, Sorensen C, Newman L, Krisher L, Madero M, Glaser J, Gárcía-Trabanino R, Romero EJ, Song Z, Jensen T, Kuwabara M, Rodriguez-Iturbe B, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F726-F733. doi: 10.1152/ajprenal.00543.2017. Epub 2018 Apr 18.

PMID:
29667911
25.

Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice.

Doke T, Ishimoto T, Hayasaki T, Ikeda S, Hasebe M, Hirayama A, Soga T, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Kadomatsu K, Maruyama S.

Metabolism. 2018 Aug;85:161-170. doi: 10.1016/j.metabol.2018.03.020. Epub 2018 Mar 29.

26.

Elevated serum uric acid increases risks for developing high LDL cholesterol and hypertriglyceridemia: A five-year cohort study in Japan.

Kuwabara M, Borghi C, Cicero AFG, Hisatome I, Niwa K, Ohno M, Johnson RJ, Lanaspa MA.

Int J Cardiol. 2018 Jun 15;261:183-188. doi: 10.1016/j.ijcard.2018.03.045. Epub 2018 Mar 13.

PMID:
29551256
27.

Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.

Lanaspa MA, Andres-Hernando A, Orlicky DJ, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe MF, Rabinowitz JD, Johnson RJ, Tolan DR.

J Clin Invest. 2018 Jun 1;128(6):2226-2238. doi: 10.1172/JCI94427. Epub 2018 Apr 23.

28.

High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism.

Lanaspa MA, Kuwabara M, Andres-Hernando A, Li N, Cicerchi C, Jensen T, Orlicky DJ, Roncal-Jimenez CA, Ishimoto T, Nakagawa T, Rodriguez-Iturbe B, MacLean PS, Johnson RJ.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3138-3143. doi: 10.1073/pnas.1713837115. Epub 2018 Mar 5. Erratum in: Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):E9509.

29.

Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation.

Johnson RJ, Bakris GL, Borghi C, Chonchol MB, Feldman D, Lanaspa MA, Merriman TR, Moe OW, Mount DB, Sanchez Lozada LG, Stahl E, Weiner DE, Chertow GM.

Am J Kidney Dis. 2018 Jun;71(6):851-865. doi: 10.1053/j.ajkd.2017.12.009. Epub 2018 Feb 27. Review.

PMID:
29496260
30.

Urinary CD80: a biomarker for a favorable response to corticosteroids in minimal change disease.

Cara-Fuentes G, Lanaspa MA, Garcia GE, Banks M, Garin EH, Johnson RJ.

Pediatr Nephrol. 2018 Jul;33(7):1101-1103. doi: 10.1007/s00467-018-3886-6. Epub 2018 Mar 1.

31.

Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.

Jensen T, Abdelmalek MF, Sullivan S, Nadeau KJ, Green M, Roncal C, Nakagawa T, Kuwabara M, Sato Y, Kang DH, Tolan DR, Sanchez-Lozada LG, Rosen HR, Lanaspa MA, Diehl AM, Johnson RJ.

J Hepatol. 2018 May;68(5):1063-1075. doi: 10.1016/j.jhep.2018.01.019. Epub 2018 Feb 2. Review.

32.

Uric Acid as a Cause of the Metabolic Syndrome.

King C, Lanaspa MA, Jensen T, Tolan DR, Sánchez-Lozada LG, Johnson RJ.

Contrib Nephrol. 2018;192:88-102. doi: 10.1159/000484283. Epub 2018 Jan 23. Review.

PMID:
29393133
33.

Uric Acid Is a Strong Risk Marker for Developing Hypertension From Prehypertension: A 5-Year Japanese Cohort Study.

Kuwabara M, Hisatome I, Niwa K, Hara S, Roncal-Jimenez CA, Bjornstad P, Nakagawa T, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Rodriguez-Iturbe B, Ohno M, Lanaspa MA, Johnson RJ.

Hypertension. 2018 Jan;71(1):78-86. doi: 10.1161/HYPERTENSIONAHA.117.10370. Epub 2017 Dec 4.

34.

Xenotransplantation: Where Are We with Potential Kidney Recipients? Recent Progress and Potential Future Clinical Trials.

Yamada K, Shah JA, Tanabe T, Lanaspa MA, Johnson RJ.

Curr Transplant Rep. 2017 Jun;4(2):101-109. doi: 10.1007/s40472-017-0149-6. Epub 2017 May 8.

35.

"Metabolically Healthy" Obesity and Hyperuricemia Increase Risk for Hypertension and Diabetes: 5-year Japanese Cohort Study.

Kuwabara M, Kuwabara R, Hisatome I, Niwa K, Roncal-Jimenez CA, Bjornstad P, Andres-Hernando A, Sato Y, Jensen T, Garcia G, Ohno M, Hill JO, Lanaspa MA, Johnson RJ.

Obesity (Silver Spring). 2017 Nov;25(11):1997-2008. doi: 10.1002/oby.22000. Epub 2017 Sep 18.

36.

Serum uric acid and acute kidney injury: A mini review.

Hahn K, Kanbay M, Lanaspa MA, Johnson RJ, Ejaz AA.

J Adv Res. 2017 Sep;8(5):529-536. doi: 10.1016/j.jare.2016.09.006. Epub 2016 Sep 24. Review.

37.

Perspective: A Historical and Scientific Perspective of Sugar and Its Relation with Obesity and Diabetes.

Johnson RJ, Sánchez-Lozada LG, Andrews P, Lanaspa MA.

Adv Nutr. 2017 May 15;8(3):412-422. doi: 10.3945/an.116.014654. Print 2017 May. Review.

38.

Angiopoietin-like-4 and minimal change disease.

Cara-Fuentes G, Segarra A, Silva-Sanchez C, Wang H, Lanaspa MA, Johnson RJ, Garin EH.

PLoS One. 2017 Apr 25;12(4):e0176198. doi: 10.1371/journal.pone.0176198. eCollection 2017.

39.

Asymptomatic Hyperuricemia Without Comorbidities Predicts Cardiometabolic Diseases: Five-Year Japanese Cohort Study.

Kuwabara M, Niwa K, Hisatome I, Nakagawa T, Roncal-Jimenez CA, Andres-Hernando A, Bjornstad P, Jensen T, Sato Y, Milagres T, Garcia G, Ohno M, Lanaspa MA, Johnson RJ.

Hypertension. 2017 Jun;69(6):1036-1044. doi: 10.1161/HYPERTENSIONAHA.116.08998. Epub 2017 Apr 10.

40.

Erratum to: Dietary and commercialized fructose: Sweet or sour?

Yerlikaya A, Dagel T, King C, Kuwabara M, Lanaspa MA, Andres-Hernando A, Covic A, Manitius J, Sag AA, Kanbay M.

Int Urol Nephrol. 2017 Sep;49(9):1699. doi: 10.1007/s11255-017-1579-x. No abstract available.

PMID:
28382575
41.

Elevated Serum Uric Acid Level Predicts Rapid Decline in Kidney Function.

Kuwabara M, Bjornstad P, Hisatome I, Niwa K, Roncal-Jimenez CA, Andres-Hernando A, Jensen T, Milagres T, Sato Y, Garcia G, Ohno M, Lanaspa MA, Johnson RJ.

Am J Nephrol. 2017;45(4):330-337. doi: 10.1159/000464260. Epub 2017 Mar 11.

42.

Dietary and commercialized fructose: Sweet or sour?

Yerlikaya A, Dagel T, King C, Kuwabara M, Lanaspa MA, Andres-Hernando A, Covic A, Manitius J, Sag AA, Kanbay M.

Int Urol Nephrol. 2017 Sep;49(9):1611-1620. doi: 10.1007/s11255-017-1544-8. Epub 2017 Feb 16. Review. Erratum in: Int Urol Nephrol. 2017 Apr 5;:.

PMID:
28210913
43.

Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice.

Andres-Hernando A, Li N, Cicerchi C, Inaba S, Chen W, Roncal-Jimenez C, Le MT, Wempe MF, Milagres T, Ishimoto T, Fini M, Nakagawa T, Johnson RJ, Lanaspa MA.

Nat Commun. 2017 Feb 13;8:14181. doi: 10.1038/ncomms14181.

44.

Increased Serum Sodium and Serum Osmolarity Are Independent Risk Factors for Developing Chronic Kidney Disease; 5 Year Cohort Study.

Kuwabara M, Hisatome I, Roncal-Jimenez CA, Niwa K, Andres-Hernando A, Jensen T, Bjornstad P, Milagres T, Cicerchi C, Song Z, Garcia G, Sánchez-Lozada LG, Ohno M, Lanaspa MA, Johnson RJ.

PLoS One. 2017 Jan 12;12(1):e0169137. doi: 10.1371/journal.pone.0169137. eCollection 2017. Erratum in: PLoS One. 2018 May 17;13(5):e0197941.

45.

Effects of exogenous desmopressin on a model of heat stress nephropathy in mice.

Roncal-Jimenez CA, Milagres T, Andres-Hernando A, Kuwabara M, Jensen T, Song Z, Bjornstad P, Garcia GE, Sato Y, Sanchez-Lozada LG, Lanaspa MA, Johnson RJ.

Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F418-F426. doi: 10.1152/ajprenal.00495.2016. Epub 2016 Dec 21.

46.

Acute kidney injury from SGLT2 inhibitors: potential mechanisms.

Hahn K, Ejaz AA, Kanbay M, Lanaspa MA, Johnson RJ.

Nat Rev Nephrol. 2016 Nov 16;12(12):711-712. doi: 10.1038/nrneph.2016.159. Review. No abstract available.

PMID:
27847389
47.

Hyponatremia with Persistent Elevated Urinary Fractional Uric Acid Excretion: Evidence for Proximal Tubular Injury?

Lee SK, Lanaspa MA, Sánchez-Lozada LG, Johnson RJ.

Kidney Blood Press Res. 2016;41(5):535-544. Epub 2016 Aug 26.

48.

A randomized, placebo-controlled, double-blind study on the effects of (-)-epicatechin on the triglyceride/HDLc ratio and cardiometabolic profile of subjects with hypertriglyceridemia: Unique in vitro effects.

Gutiérrez-Salmeán G, Meaney E, Lanaspa MA, Cicerchi C, Johnson RJ, Dugar S, Taub P, Ramírez-Sánchez I, Villarreal F, Schreiner G, Ceballos G.

Int J Cardiol. 2016 Nov 15;223:500-506. doi: 10.1016/j.ijcard.2016.08.158. Epub 2016 Aug 8.

PMID:
27552564
49.

Aging-associated renal disease in mice is fructokinase dependent.

Roncal-Jimenez CA, Ishimoto T, Lanaspa MA, Milagres T, Hernando AA, Jensen T, Miyazaki M, Doke T, Hayasaki T, Nakagawa T, Marumaya S, Long DA, Garcia GE, Kuwabara M, Sánchez-Lozada LG, Kang DH, Johnson RJ.

Am J Physiol Renal Physiol. 2016 Oct 1;311(4):F722-F730. doi: 10.1152/ajprenal.00306.2016. Epub 2016 Jul 27.

50.

Bioactivity-Guided Identification of Botanical Inhibitors of Ketohexokinase.

Le MT, Lanaspa MA, Cicerchi CM, Rana J, Scholten JD, Hunter BL, Rivard CJ, Randolph RK, Johnson RJ.

PLoS One. 2016 Jun 20;11(6):e0157458. doi: 10.1371/journal.pone.0157458. eCollection 2016.

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