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Items: 1 to 50 of 97

1.

Insulinoma-Associated-1: From Neuroendocrine Tumor Marker to Cancer Therapeutics.

Chen C, Notkins AL, Lan MS.

Mol Cancer Res. 2019 Aug;17(8):1597-1604. doi: 10.1158/1541-7786.MCR-19-0286. Epub 2019 May 21. Review.

PMID:
31113827
2.

5'-Iodotubercidin represses insulinoma-associated-1 expression, decreases cAMP levels, and suppresses human neuroblastoma cell growth.

Chen C, Breslin MB, Guidry JJ, Lan MS.

J Biol Chem. 2019 Apr 5;294(14):5456-5465. doi: 10.1074/jbc.RA118.006761. Epub 2019 Feb 12.

PMID:
30755485
3.

Targeted deletion of Insm2 in mice result in reduced insulin secretion and glucose intolerance.

Wang L, Sun ZS, Xiang B, Wei CJ, Wang Y, Sun K, Chen G, Lan MS, Carmona GN, Notkins AL, Cai T.

J Transl Med. 2018 Oct 25;16(1):297. doi: 10.1186/s12967-018-1665-6.

4.

Sonic hedgehog signaling pathway promotes INSM1 transcription factor in neuroendocrine lung cancer.

Chen C, Breslin MB, Lan MS.

Cell Signal. 2018 Jun;46:83-91. doi: 10.1016/j.cellsig.2018.02.014. Epub 2018 Mar 1.

PMID:
29501727
6.

Ectopic expression of a small cell lung cancer transcription factor, INSM1 impairs alveologenesis in lung development.

Chen C, Breslin MB, Lan MS.

BMC Pulm Med. 2016 Apr 12;16:49. doi: 10.1186/s12890-016-0215-3.

7.

Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells.

Sparks AE, Chen C, Breslin MB, Lan MS.

J Biol Chem. 2016 May 20;291(21):11313-22. doi: 10.1074/jbc.M116.722488. Epub 2016 Apr 5.

8.

Tumor-specific promoter-driven adenoviral therapy for insulinoma.

Tseng AW, Chen C, Breslin MB, Lan MS.

Cell Oncol (Dordr). 2016 Jun;39(3):279-86. doi: 10.1007/s13402-016-0274-8. Epub 2016 Feb 22.

PMID:
26902080
9.

Detection of neuroendocrine tumors using promoter-specific secreted Gaussia luciferase.

Tseng AW, Akerstrom V, Chen C, Breslin MB, Lan MS.

Int J Oncol. 2016 Jan;48(1):173-80. doi: 10.3892/ijo.2015.3223. Epub 2015 Oct 30.

PMID:
26530405
10.

INSM1 increases N-myc stability and oncogenesis via a positive-feedback loop in neuroblastoma.

Chen C, Breslin MB, Lan MS.

Oncotarget. 2015 Nov 3;6(34):36700-12. doi: 10.18632/oncotarget.5485.

11.

Norditerpenoid alkaloids from Delphinium anthriscifolium.

Wang S, Zhou XL, Gong XM, Fan XY, Lan MS.

J Asian Nat Prod Res. 2016;18(2):141-6. doi: 10.1080/10286020.2015.1056522. Epub 2015 Aug 6.

PMID:
26245883
12.

Expression of biologically active TAT-fused recombinant islet transcription factors.

Lan MS, Chen C, Saunee NA, Zhang T, Breslin MB.

Life Sci. 2014 Sep 26;114(1):45-50. doi: 10.1016/j.lfs.2014.08.001. Epub 2014 Aug 14.

PMID:
25128855
13.

Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.

Zhang T, Chen C, Breslin MB, Song K, Lan MS.

Cell Signal. 2014 Apr;26(4):740-7. doi: 10.1016/j.cellsig.2013.12.014. Epub 2014 Jan 7.

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Modifications to the INSM1 promoter to preserve specificity and activity for use in adenoviral gene therapy of neuroendocrine carcinomas.

Akerstrom V, Chen C, Lan MS, Breslin MB.

Cancer Gene Ther. 2012 Dec;19(12):828-38. doi: 10.1038/cgt.2012.66. Epub 2012 Oct 19.

PMID:
23079673
18.

Arylnaphthalene lignan glycosides and other constituents from Phyllanthus reticulatus.

Ma JX, Lan MS, Qu SJ, Tan JJ, Luo HF, Tan CH, Zhu DY.

J Asian Nat Prod Res. 2012;14(11):1073-7. doi: 10.1080/10286020.2012.712040. Epub 2012 Aug 28.

PMID:
22924384
19.

[Study on chemical constituents of the ethyl acetate extract from Blumea aromatica].

Lan MS, Luo C, Tan CH, Chen L, Wei S, Zhu DY.

Zhong Yao Cai. 2012 Feb;35(2):229-31. Chinese.

PMID:
22822668
20.

The transcription factor encyclopedia.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O'Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.

Genome Biol. 2012;13(3):R24. doi: 10.1186/gb-2012-13-3-r24.

21.

Functional role of an islet transcription factor, INSM1/IA-1, on pancreatic acinar cell trans-differentiation.

Zhang T, Saunee NA, Breslin MB, Song K, Lan MS.

J Cell Physiol. 2012 Jun;227(6):2470-9. doi: 10.1002/jcp.22982.

22.

Recombinant MafA protein containing its own protein transduction domain stimulates insulin gene expression in IEC-6 cells.

Lu J, Luo H, Wu H, Lan MS, Tan J, Lu D.

Life Sci. 2011 Jul 18;89(3-4):72-7. doi: 10.1016/j.lfs.2011.04.012. Epub 2011 Apr 30.

PMID:
21565207
23.

Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1.

Cai T, Chen X, Wang R, Xu H, You Y, Zhang T, Lan MS, Notkins AL.

Endocrinology. 2011 May;152(5):1961-9. doi: 10.1210/en.2010-1065. Epub 2011 Feb 22.

24.

Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats.

Jiang M, Zhang Y, Liu M, Lan MS, Fei J, Fan W, Gao X, Lu D.

Endocrinology. 2011 Apr;152(4):1284-9. doi: 10.1210/en.2010-1162. Epub 2011 Jan 14.

PMID:
21239437
25.

Both polymorphic variable number of tandem repeats and autoimmune regulator modulate differential expression of insulin in human thymic epithelial cells.

Cai CQ, Zhang T, Breslin MB, Giraud M, Lan MS.

Diabetes. 2011 Jan;60(1):336-44. doi: 10.2337/db10-0255. Epub 2010 Sep 28.

26.

[Studies on the chemical constituents of Teyou 2 Folium Mori].

Chen L, Lan MS.

Zhong Yao Cai. 2010 Mar;33(3):380-2. Chinese.

PMID:
20681303
27.

Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.

Chen QY, Zhang T, Pincus SH, Wu S, Ricks D, Liu D, Sun Z, Maclaren N, Lan MS.

J Immunol. 2010 May 1;184(9):5047-54. doi: 10.4049/jimmunol.0901912. Epub 2010 Apr 2.

28.

Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation.

Zhang T, Wang H, Saunee NA, Breslin MB, Lan MS.

Endocrinology. 2010 May;151(5):2030-9. doi: 10.1210/en.2009-1224. Epub 2010 Mar 9.

29.

INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumors.

Wang HW, Breslin MB, Chen C, Akerstrom V, Zhong Q, Lan MS.

Hum Gene Ther. 2009 Nov;20(11):1308-18. doi: 10.1089/hum.2008.168.

30.

Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation.

Lan MS, Breslin MB.

FASEB J. 2009 Jul;23(7):2024-33. doi: 10.1096/fj.08-125971. Epub 2009 Feb 26. Review.

31.

Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest.

Zhang T, Liu WD, Saunee NA, Breslin MB, Lan MS.

J Biol Chem. 2009 Feb 27;284(9):5574-81. doi: 10.1074/jbc.M808843200. Epub 2009 Jan 5.

32.

Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential.

Jiang MH, Fei J, Lan MS, Lu ZP, Liu M, Fan WW, Gao X, Lu DR.

Diabetologia. 2008 Aug;51(8):1525-33. doi: 10.1007/s00125-008-1034-8. Epub 2008 May 22.

PMID:
18496667
33.

Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription.

Wang HW, Muguira M, Liu WD, Zhang T, Chen C, Aucoin R, Breslin MB, Lan MS.

J Endocrinol. 2008 Jul;198(1):29-39. doi: 10.1677/JOE-08-0001. Epub 2008 Apr 16.

34.

Pax4 paired domain mediates direct protein transduction into mammalian cells.

Lu J, Li G, Lan MS, Zhang S, Fan W, Wang H, Lu D.

Endocrinology. 2007 Nov;148(11):5558-65. Epub 2007 Aug 23.

PMID:
17717051
35.
36.

Neurogenin 3 recruits CBP co-activator to facilitate histone H3/H4 acetylation in the target gene INSM1.

Breslin MB, Wang HW, Pierce A, Aucoin R, Lan MS.

FEBS Lett. 2007 Mar 6;581(5):949-54. Epub 2007 Feb 7.

37.

Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells.

Nelson BR, Hartman BH, Georgi SA, Lan MS, Reh TA.

Dev Biol. 2007 Apr 15;304(2):479-98. Epub 2007 Jan 8.

38.

Coupling of glucose response element from L-type pyruvate kinase and G6Pase promoter enhances glucose responsive activity in hepatoma cells.

Lan MS, Wang HW, Chong J, Breslin MB.

Mol Cell Biochem. 2007 Jun;300(1-2):191-6. Epub 2006 Dec 8.

PMID:
17160355
39.

Sodium tanshinone IIA sulfonate derived from Slavia miltiorrhiza Bunge up-regulate the expression of prolactin releasing peptide (PrRP) in the medulla oblongata in ovariectomized rats.

Xiao Y, Qing WX, Lan MS, Ying CB.

Biochem Pharmacol. 2006 Aug 28;72(5):582-7. Epub 2006 Jul 17. Erratum in: Biochem Pharmacol. 2007 Feb 1;73(3):458. Xiaoa, Yao [corrected to Xiao, Yao].

PMID:
16846593
40.
41.

The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer.

Pedersen N, Pedersen MW, Lan MS, Breslin MB, Poulsen HS.

Cancer Gene Ther. 2006 Apr;13(4):375-84.

PMID:
16052225
42.

An effective alternate cloning strategy for unstable mouse genomic sequences.

Lan MS, Muguira M.

Biochem Biophys Res Commun. 2005 May 13;330(3):641-4.

PMID:
15809045
43.

Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology.

Conn KJ, Gao W, McKee A, Lan MS, Ullman MD, Eisenhauer PB, Fine RE, Wells JM.

Brain Res. 2004 Oct 1;1022(1-2):164-72.

PMID:
15353226
44.

Autoantibodies against IA-2, GAD, and topoisomerase II in type 1 diabetic patients.

Chang YH, Shiau MY, Tsai ST, Lan MS.

Biochem Biophys Res Commun. 2004 Jul 30;320(3):802-9.

PMID:
15240119
45.

Identification of three genomic haplotypes 5' to the human CD1D gene and their distribution in four ethnic groups.

Chen QY, Jackson N, Vargas A, Chalew S, Rao J, Batzer M, Lan MS, Chang YH, Mokhashi M, Liu D.

Tissue Antigens. 2003 Nov;62(5):442-8.

PMID:
14617053
46.
47.

Multiple autoantibodies as predictors of Type 1 diabetes in a general population.

Maclaren NK, Lan MS, Schatz D, Malone J, Notkins AL, Krischer J.

Diabetologia. 2003 Jun;46(6):873-4. Epub 2003 Jun 11. No abstract available.

PMID:
12802500
48.
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