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A simple and highly purified method for isolation of glomeruli from the mouse kidney.

Wang H, Sheng J, He H, Chen X, Li J, Tan R, Wang L, Lan HY.

Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1217-F1223. doi: 10.1152/ajprenal.00293.2019. Epub 2019 Sep 30.


Altered fecal microbiomes and short chain fatty acids of crew members with periodic intake of prepackaged food in a ground-based space station simulator for 50 days.

Dong HS, Lan HY, Yu YB, Li HF, Lin JM.

Travel Med Infect Dis. 2019 Sep 11:101480. doi: 10.1016/j.tmaid.2019.101480. [Epub ahead of print] No abstract available.


Quercetin protects against cisplatin-induced acute kidney injury by inhibiting Mincle/Syk/NF-κB signaling maintained macrophage inflammation.

Tan RZ, Wang C, Deng C, Zhong X, Yan Y, Luo Y, Lan HY, He T, Wang L.

Phytother Res. 2019 Sep 9. doi: 10.1002/ptr.6507. [Epub ahead of print]


Macrophages in Renal Fibrosis.

Meng XM, Mak TS, Lan HY.

Adv Exp Med Biol. 2019;1165:285-303. doi: 10.1007/978-981-13-8871-2_13. Review.


Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.

Li J, Yang KY, Tam RCY, Chan VW, Lan HY, Hori S, Zhou B, Lui KO.

Theranostics. 2019 Jun 9;9(15):4324-4341. doi: 10.7150/thno.32734. eCollection 2019.


Relationship between the status of phospholipase A2 receptor and prognosis of idiopathic membranous nephropathy.

Li YQ, Liu ZZ, Lin KX, Liu RH, Ni L, Liu GX, Lan HY, Shi YJ.

Nephrology (Carlton). 2019 Jun 21. doi: 10.1111/nep.13625. [Epub ahead of print]


Petchiether A attenuates obstructive nephropathy by suppressing TGF-β/Smad3 and NF-κB signalling.

You YK, Luo Q, Wu WF, Zhang JJ, Zhu HJ, Lao L, Lan HY, Chen HY, Cheng YX.

J Cell Mol Med. 2019 Aug;23(8):5576-5587. doi: 10.1111/jcmm.14454. Epub 2019 Jun 18.


Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury.

Lv LL, Feng Y, Wu M, Wang B, Li ZL, Zhong X, Wu WJ, Chen J, Ni HF, Tang TT, Tang RN, Lan HY, Liu BC.

Cell Death Differ. 2019 May 16. doi: 10.1038/s41418-019-0349-y. [Epub ahead of print]


LRNA9884, a Novel Smad3-Dependent Long Noncoding RNA, Promotes Diabetic Kidney Injury in db/db Mice via Enhancing MCP-1-Dependent Renal Inflammation.

Zhang YY, Tang PM, Tang PC, Xiao J, Huang XR, Yu C, Ma RCW, Lan HY.

Diabetes. 2019 Jul;68(7):1485-1498. doi: 10.2337/db18-1075. Epub 2019 May 2.


RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer.

Cheng WC, Liao TT, Lin CC, Yuan LE, Lan HY, Lin HH, Teng HW, Chang HC, Lin CH, Yang CY, Huang SC, Jiang JK, Yang SH, Yang MH, Hwang WL.

Int J Cancer. 2019 Oct 15;145(8):2209-2224. doi: 10.1002/ijc.32338. Epub 2019 Apr 30.


Macrophage migration inhibitory factor promotes renal injury induced by ischemic reperfusion.

Li JH, Tang Y, Lv J, Wang XH, Yang H, Tang PMK, Huang XR, He ZJ, Zhou ZJ, Huang QY, Klug J, Meinhardt A, Fingerle-Rowson G, Xu AP, Zheng ZH, Lan HY.

J Cell Mol Med. 2019 Jun;23(6):3867-3877. doi: 10.1111/jcmm.14234. Epub 2019 Apr 9.


Extracellular Vesicles: Opportunities and Challenges for the Treatment of Renal Diseases.

Tang TT, Lv LL, Lan HY, Liu BC.

Front Physiol. 2019 Mar 19;10:226. doi: 10.3389/fphys.2019.00226. eCollection 2019. Review.


Phytochemistry, Pharmacological Activities, Toxicity and Clinical Application of Momordica cochinchinensis.

Lan HY, Zhao B, Shen YL, Li XQ, Wang SJ, Zhang LJ, Zhang H.

Curr Pharm Des. 2019;25(6):715-728. doi: 10.2174/1381612825666190329123436.


Author Correction: Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition.

Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY, Yang WH, Huang CH, Kao SY, Tzeng CH, Tai SK, Chang SY, Lee OK, Wu KJ.

Nat Cell Biol. 2019 Apr;21(4):533. doi: 10.1038/s41556-019-0290-9.


Author Correction: MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells.

Hwang WL, Jiang JK, Yang SH, Huang TS, Lan HY, Teng HW, Yang CY, Tsai YP, Lin CH, Wang HW, Yang MH.

Nat Cell Biol. 2019 May;21(5):664. doi: 10.1038/s41556-019-0286-5.


Macrophages: versatile players in renal inflammation and fibrosis.

Tang PM, Nikolic-Paterson DJ, Lan HY.

Nat Rev Nephrol. 2019 Mar;15(3):144-158. doi: 10.1038/s41581-019-0110-2. Epub 2019 Jan 28. Review.


Letter by Zhang et al Regarding Article, "Heart Failure Stimulates Tumor Growth by Circulating Factors".

Zhang J, Lan HY, Wan S.

Circulation. 2019 Jan 29;139(5):718-719. doi: 10.1161/CIRCULATIONAHA.118.037275. No abstract available.


Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer.

Hwang WL, Lan HY, Cheng WC, Huang SC, Yang MH.

J Hematol Oncol. 2019 Jan 25;12(1):10. doi: 10.1186/s13045-019-0699-4.


Snail-induced claudin-11 prompts collective migration for tumour progression.

Li CF, Chen JY, Ho YH, Hsu WH, Wu LC, Lan HY, Hsu DS, Tai SK, Chang YC, Yang MH.

Nat Cell Biol. 2019 Feb;21(2):251-262. doi: 10.1038/s41556-018-0268-z. Epub 2019 Jan 21.


Curcumin relieved cisplatin-induced kidney inflammation through inhibiting Mincle-maintained M1 macrophage phenotype.

Tan RZ, Liu J, Zhang YY, Wang HL, Li JC, Liu YH, Zhong X, Zhang YW, Yan Y, Lan HY, Wang L.

Phytomedicine. 2019 Jan;52:284-294. doi: 10.1016/j.phymed.2018.09.210. Epub 2018 Sep 25.


Cardiomyocyte-specific loss of RNA polymerase II subunit 5-mediating protein causes myocardial dysfunction and heart failure.

Zhang J, Sheng J, Dong L, Xu Y, Yu L, Liu Y, Huang X, Wan S, Lan HY, Wang H.

Cardiovasc Res. 2019 Sep 1;115(11):1617-1628. doi: 10.1093/cvr/cvy307.


[Transforming growth factor-β and renal fibrosis].

Meng XM, Lan HY.

Sheng Li Xue Bao. 2018 Dec 25;70(6):612-622. Review. Chinese.


Loss of Smad7 Promotes Inflammation in Rheumatoid Arthritis.

Zhou G, Sun X, Qin Q, Lv J, Cai Y, Wang M, Mu R, Lan HY, Wang QW.

Front Immunol. 2018 Nov 2;9:2537. doi: 10.3389/fimmu.2018.02537. eCollection 2018.


Progression of diabetic kidney disease and trajectory of kidney function decline in Chinese patients with Type 2 diabetes.

Jiang G, Luk AOY, Tam CHT, Xie F, Carstensen B, Lau ESH, Lim CKP, Lee HM, Ng ACW, Ng MCY, Ozaki R, Kong APS, Chow CC, Yang X, Lan HY, Tsui SKW, Fan X, Szeto CC, So WY, Chan JCN, Ma RCW; Hong Kong Diabetes Register TRS Study Group.

Kidney Int. 2019 Jan;95(1):178-187. doi: 10.1016/j.kint.2018.08.026. Epub 2018 Nov 8.


Role of C-reactive protein in the pathogenesis of acute kidney injury.

Tang Y, Mak SK, Xu AP, Lan HY.

Nephrology (Carlton). 2018 Oct;23 Suppl 4:50-52. doi: 10.1111/nep.13454. Review.


LncRNAs in TGF-β-Driven Tissue Fibrosis.

Tang PM, Zhang YY, Lan HY.

Noncoding RNA. 2018 Oct 4;4(4). pii: E26. doi: 10.3390/ncrna4040026. Review.


The baseline levels and risk factors for high-sensitive C-reactive protein in Chinese healthy population.

Tang Y, Liang P, Chen J, Fu S, Liu B, Feng M, Lin B, Lee B, Xu A, Lan HY.

Immun Ageing. 2018 Sep 8;15:21. doi: 10.1186/s12979-018-0126-7. eCollection 2018.


Blocking Macrophage Migration Inhibitory Factor Protects Against Cisplatin-Induced Acute Kidney Injury in Mice.

Li J, Tang Y, Tang PMK, Lv J, Huang XR, Carlsson-Skwirut C, Da Costa L, Aspesi A, Fröhlich S, Szczęśniak P, Lacher P, Klug J, Meinhardt A, Fingerle-Rowson G, Gong R, Zheng Z, Xu A, Lan HY.

Mol Ther. 2018 Oct 3;26(10):2523-2532. doi: 10.1016/j.ymthe.2018.07.014. Epub 2018 Jul 17.


Combination of Asiatic Acid and Naringenin Modulates NK Cell Anti-cancer Immunity by Rebalancing Smad3/Smad7 Signaling.

Lian GY, Wang QM, Tang PM, Zhou S, Huang XR, Lan HY.

Mol Ther. 2018 Sep 5;26(9):2255-2266. doi: 10.1016/j.ymthe.2018.06.016. Epub 2018 Jun 22.


Enhanced Cancer Immunotherapy with Smad3-Silenced NK-92 Cells.

Wang QM, Tang PM, Lian GY, Li C, Li J, Huang XR, To KF, Lan HY.

Cancer Immunol Res. 2018 Aug;6(8):965-977. doi: 10.1158/2326-6066.CIR-17-0491. Epub 2018 Jun 18.


The preventive and therapeutic implication for renal fibrosis by targetting TGF-β/Smad3 signaling.

Zhang Y, Meng XM, Huang XR, Lan HY.

Clin Sci (Lond). 2018 Jul 9;132(13):1403-1415. doi: 10.1042/CS20180243. Print 2018 Jul 16.


Transforming growth factor-β signalling in renal fibrosis: from Smads to non-coding RNAs.

Tang PM, Zhang YY, Mak TS, Tang PC, Huang XR, Lan HY.

J Physiol. 2018 Aug;596(16):3493-3503. doi: 10.1113/JP274492. Epub 2018 Jun 28. Review.


Epithelial-mesenchymal transition softens head and neck cancer cells to facilitate migration in 3D environments.

Chen YQ, Lan HY, Wu YC, Yang WH, Chiou A, Yang MH.

J Cell Mol Med. 2018 May 4. doi: 10.1111/jcmm.13656. [Epub ahead of print]


Effects of a supportive care bundle on sleep variables of preterm infants during hospitalization.

Lan HY, Yang L, Hsieh KH, Yin T, Chang YC, Liaw JJ.

Res Nurs Health. 2018 Jun;41(3):281-291. doi: 10.1002/nur.21865. Epub 2018 Apr 20.


Editorial: Advances in Mechanisms of Renal Fibrosis.

Lan HY, Nikolic-Paterson DJ.

Front Physiol. 2018 Mar 23;9:284. doi: 10.3389/fphys.2018.00284. eCollection 2018. No abstract available.


RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism.

Liu W, Chen B, Wang Y, Meng C, Huang H, Huang XR, Qin J, Mulay SR, Anders HJ, Qiu A, Yang B, Freeman GJ, Lu HJ, Lin HY, Zheng ZH, Lan HY, Huang Y, Xia Y.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1475-E1484. doi: 10.1073/pnas.1716959115. Epub 2018 Jan 30.


A Novel Feeder-free System for Mass Production of Murine Natural Killer Cells In Vitro.

Tang PM, Tang PC, Chung JY, Hung JSC, Wang QM, Lian GY, Sheng J, Huang XR, To KF, Lan HY.

J Vis Exp. 2018 Jan 9;(131). doi: 10.3791/56785.


Renal tubule injury: a driving force toward chronic kidney disease.

Liu BC, Tang TT, Lv LL, Lan HY.

Kidney Int. 2018 Mar;93(3):568-579. doi: 10.1016/j.kint.2017.09.033. Epub 2018 Jan 17. Review.


Lethal (3) malignant brain tumor-like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage-p53-apoptosis pathway in renal tubular cells.

Huang H, Xu C, Wang Y, Meng C, Liu W, Zhao Y, Huang XR, You W, Feng B, Zheng ZH, Huang Y, Lan HY, Qin J, Xia Y.

Kidney Int. 2018 Apr;93(4):855-870. doi: 10.1016/j.kint.2017.09.030. Epub 2017 Dec 21.


Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b.

Sun SF, Tang PMK, Feng M, Xiao J, Huang XR, Li P, Ma RCW, Lan HY.

Diabetes. 2018 Apr;67(4):731-744. doi: 10.2337/db17-0816. Epub 2017 Dec 8.


TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis.

Feng M, Tang PM, Huang XR, Sun SF, You YK, Xiao J, Lv LL, Xu AP, Lan HY.

Mol Ther. 2018 Jan 3;26(1):148-161. doi: 10.1016/j.ymthe.2017.09.024. Epub 2017 Oct 5.


The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring.

Tang PM, Zhou S, Li CJ, Liao J, Xiao J, Wang QM, Lian GY, Li J, Huang XR, To KF, Ng CF, Chong CC, Ma RC, Lee TL, Lan HY.

Kidney Int. 2018 Jan;93(1):173-187. doi: 10.1016/j.kint.2017.07.026. Epub 2017 Oct 14.


Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin Degradation.

Liu Z, Huang XR, Chen HY, Fung E, Liu J, Lan HY.

Hypertension. 2017 Oct;70(4):822-830. doi: 10.1161/HYPERTENSIONAHA.117.09600. Epub 2017 Aug 14.


Factors Associated With Preterm Infants' Circadian Sleep/Wake Patterns at the Hospital.

Lan HY, Yin T, Chen JL, Chang YC, Liaw JJ.

Clin Nurs Res. 2019 May;28(4):456-472. doi: 10.1177/1054773817724960. Epub 2017 Aug 9.


Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis.

Zhang JT, Wang Y, Chen JJ, Zhang XH, Dong JD, Tsang LL, Huang XR, Cai Z, Lan HY, Jiang XH, Chan HC.

Sci Rep. 2017 Jul 12;7(1):5233. doi: 10.1038/s41598-017-05435-5.


Serum levels of WNT1-inducible signaling pathway protein-1 (WISP-1): a noninvasive biomarker of renal fibrosis in subjects with chronic kidney disease.

Zhong X, Tu YJ, Li Y, Zhang P, Wang W, Chen SS, Li L, Chung AC, Lan HY, Chen HY, Li GS, Wang L.

Am J Transl Res. 2017 Jun 15;9(6):2920-2932. eCollection 2017.


The incidence, risk factors and in-hospital mortality of acute kidney injury in patients after abdominal aortic aneurysm repair surgery.

Tang Y, Chen J, Huang K, Luo D, Liang P, Feng M, Chai W, Fung E, Lan HY, Xu A.

BMC Nephrol. 2017 May 31;18(1):184. doi: 10.1186/s12882-017-0594-6.


Smad7 protects against acute kidney injury by rescuing tubular epithelial cells from the G1 cell cycle arrest.

Fu S, Tang Y, Huang XR, Feng M, Xu AP, Lan HY.

Clin Sci (Lond). 2017 Jul 13;131(15):1955-1969. doi: 10.1042/CS20170127. Print 2017 Aug 1.


The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis.

Yang C, Huang XR, Fung E, Liu HF, Lan HY.

Sci Rep. 2017 May 3;7(1):1481. doi: 10.1038/s41598-017-01515-8.


TGF-β1 signaling in kidney disease: From Smads to long non-coding RNAs.

Tang PM, Tang PC, Chung JY, Lan HY.

Noncoding RNA Res. 2017 Apr 8;2(1):68-73. doi: 10.1016/j.ncrna.2017.04.001. eCollection 2017 Mar. Review.

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