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Items: 1 to 50 of 79

1.

Endothelial cell clonal expansion in the development of cerebral cavernous malformations.

Malinverno M, Maderna C, Abu Taha A, Corada M, Orsenigo F, Valentino M, Pisati F, Fusco C, Graziano P, Giannotta M, Yu QC, Zeng YA, Lampugnani MG, Magnusson PU, Dejana E.

Nat Commun. 2019 Jun 24;10(1):2761. doi: 10.1038/s41467-019-10707-x.

2.

Endothelial cell transitions.

Dejana E, Lampugnani MG.

Science. 2018 Nov 16;362(6416):746-747. doi: 10.1126/science.aas9432. No abstract available.

PMID:
30442789
3.

Corrigendum: Vascular Endothelial (VE)-Cadherin, Endothelial Adherens Junctions, and Vascular Disease.

Lampugnani MG, Dejana E, Giampietro C.

Cold Spring Harb Perspect Biol. 2017 Oct 3;9(10). pii: a033720. doi: 10.1101/cshperspect.a033720. No abstract available.

4.

Deregulated TGF-β/BMP Signaling in Vascular Malformations.

Cunha SI, Magnusson PU, Dejana E, Lampugnani MG.

Circ Res. 2017 Sep 29;121(8):981-999. doi: 10.1161/CIRCRESAHA.117.309930. Review.

PMID:
28963191
5.

Vascular Endothelial (VE)-Cadherin, Endothelial Adherens Junctions, and Vascular Disease.

Lampugnani MG, Dejana E, Giampietro C.

Cold Spring Harb Perspect Biol. 2018 Oct 1;10(10). pii: a029322. doi: 10.1101/cshperspect.a029322. Review. Erratum in: Cold Spring Harb Perspect Biol. 2017 Oct 3;9(10 ):.

PMID:
28851747
6.

Endothelial cell disease: emerging knowledge from cerebral cavernous malformations.

Lampugnani MG, Malinverno M, Dejana E, Rudini N.

Curr Opin Hematol. 2017 May;24(3):256-264. doi: 10.1097/MOH.0000000000000338. Review.

PMID:
28212190
7.

Endothelial Cells Lining Sporadic Cerebral Cavernous Malformation Cavernomas Undergo Endothelial-to-Mesenchymal Transition.

Bravi L, Malinverno M, Pisati F, Rudini N, Cuttano R, Pallini R, Martini M, Larocca LM, Locatelli M, Levi V, Bertani GA, Dejana E, Lampugnani MG.

Stroke. 2016 Mar;47(3):886-90. doi: 10.1161/STROKEAHA.115.011867. Epub 2016 Feb 2.

PMID:
26839352
8.

The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling.

Giampietro C, Disanza A, Bravi L, Barrios-Rodiles M, Corada M, Frittoli E, Savorani C, Lampugnani MG, Boggetti B, Niessen C, Wrana JL, Scita G, Dejana E.

J Cell Biol. 2015 Dec 21;211(6):1177-92. doi: 10.1083/jcb.201501089. Epub 2015 Dec 14.

9.

KLF4 is a key determinant in the development and progression of cerebral cavernous malformations.

Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E.

EMBO Mol Med. 2016 Jan 1;8(1):6-24. doi: 10.15252/emmm.201505433.

10.

Sulindac metabolites decrease cerebrovascular malformations in CCM3-knockout mice.

Bravi L, Rudini N, Cuttano R, Giampietro C, Maddaluno L, Ferrarini L, Adams RH, Corada M, Boulday G, Tournier-Lasserve E, Dejana E, Lampugnani MG.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8421-6. doi: 10.1073/pnas.1501352112. Epub 2015 Jun 24.

11.

The role of microvascular endothelial WNT signaling the formation of the blood brain barrier.

Lampugnani MG, Bravi L, Dejana E.

Springerplus. 2015 Jun 12;4(Suppl 1):L47. doi: 10.1186/2193-1801-4-S1-L47. eCollection 2015. No abstract available.

12.

Differential adhesion drives angiogenesis.

Dejana E, Lampugnani MG.

Nat Cell Biol. 2014 Apr;16(4):305-6. doi: 10.1038/ncb2943.

PMID:
24691258
13.

VE-cadherin at a glance.

Bravi L, Dejana E, Lampugnani MG.

Cell Tissue Res. 2014 Mar;355(3):515-22. doi: 10.1007/s00441-014-1843-7. Epub 2014 Mar 20.

PMID:
24643676
14.

EndMT contributes to the onset and progression of cerebral cavernous malformations.

Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, Ferrarini L, Orsenigo F, Papa E, Boulday G, Tournier-Lasserve E, Chapon F, Richichi C, Retta SF, Lampugnani MG, Dejana E.

Nature. 2013 Jun 27;498(7455):492-6. doi: 10.1038/nature12207. Epub 2013 Jun 9.

PMID:
23748444
15.

Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory.

Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G.

Dev Cell. 2013 Mar 25;24(6):586-99. doi: 10.1016/j.devcel.2013.01.022. Epub 2013 Mar 7. Erratum in: Dev Cell. 2014 Jul 28;30(2):246-7.

16.

Endothelial cell-to-cell junctions: adhesion and signaling in physiology and pathology.

Lampugnani MG.

Cold Spring Harb Perspect Med. 2012 Oct 1;2(10). pii: a006528. doi: 10.1101/cshperspect.a006528. Review.

17.

Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells.

Giampietro C, Taddei A, Corada M, Sarra-Ferraris GM, Alcalay M, Cavallaro U, Orsenigo F, Lampugnani MG, Dejana E.

Blood. 2012 Mar 1;119(9):2159-70. doi: 10.1182/blood-2011-09-381012. Epub 2012 Jan 12.

PMID:
22246030
18.

Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?

Lampugnani MG.

J Biol. 2010;9(3):16. doi: 10.1186/jbiol232. Epub 2010 Apr 8. Review.

19.

CCM1 regulates vascular-lumen organization by inducing endothelial polarity.

Lampugnani MG, Orsenigo F, Rudini N, Maddaluno L, Boulday G, Chapon F, Dejana E.

J Cell Sci. 2010 Apr 1;123(Pt 7):1073-80. doi: 10.1242/jcs.059329.

20.

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.

Mazzone M, Dettori D, de Oliveira RL, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, de Almodovar CR, De Smet F, Vinckier S, Aragonés J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P.

Cell. 2009 Mar 6;136(5):839-851. doi: 10.1016/j.cell.2009.01.020. Epub 2009 Feb 12.

21.

Combinatorial interaction between CCM pathway genes precipitates hemorrhagic stroke.

Gore AV, Lampugnani MG, Dye L, Dejana E, Weinstein BM.

Dis Model Mech. 2008 Nov-Dec;1(4-5):275-81. doi: 10.1242/dmm.000513. Epub 2008 Oct 28.

22.

The role of adherens junctions and VE-cadherin in the control of vascular permeability.

Dejana E, Orsenigo F, Lampugnani MG.

J Cell Sci. 2008 Jul 1;121(Pt 13):2115-22. doi: 10.1242/jcs.017897. Review.

23.

The control of endothelial cell functions by adherens junctions.

Lampugnani MG, Dejana E.

Novartis Found Symp. 2007;283:4-13; discussion 13-7, 238-41.

PMID:
18300410
24.

Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration.

Turowski P, Martinelli R, Crawford R, Wateridge D, Papageorgiou AP, Lampugnani MG, Gamp AC, Vestweber D, Adamson P, Dejana E, Greenwood J.

J Cell Sci. 2008 Jan 1;121(Pt 1):29-37.

25.

Adherens junctions in endothelial cells regulate vessel maintenance and angiogenesis.

Lampugnani MG, Dejana E.

Thromb Res. 2007;120 Suppl 2:S1-6. Erratum in: Thromb Res. 2008;123(1):187-90.

PMID:
18023702
26.

Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments.

Lampugnani MG, Orsenigo F, Gagliani MC, Tacchetti C, Dejana E.

J Cell Biol. 2006 Aug 14;174(4):593-604. Epub 2006 Aug 7.

27.

A monoclonal antibody to vascular endothelial-cadherin inhibits tumor angiogenesis without side effects on endothelial permeability.

Corada M, Zanetta L, Orsenigo F, Breviario F, Lampugnani MG, Bernasconi S, Liao F, Hicklin DJ, Bohlen P, Dejana E.

Blood. 2002 Aug 1;100(3):905-11.

PMID:
12130501
28.

VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam.

Lampugnani MG, Zanetti A, Breviario F, Balconi G, Orsenigo F, Corada M, Spagnuolo R, Betson M, Braga V, Dejana E.

Mol Biol Cell. 2002 Apr;13(4):1175-89.

29.

Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism to control vascular endothelial growth factor receptor-2 signaling.

Zanetti A, Lampugnani MG, Balconi G, Breviario F, Corada M, Lanfrancone L, Dejana E.

Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):617-22.

PMID:
11950700
30.

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability.

Corada M, Liao F, Lindgren M, Lampugnani MG, Breviario F, Frank R, Muller WA, Hicklin DJ, Bohlen P, Dejana E.

Blood. 2001 Mar 15;97(6):1679-84.

PMID:
11238107
31.

The molecular organization of endothelial junctions and their functional role in vascular morphogenesis and permeability.

Dejana E, Lampugnani MG, Martinez-Estrada O, Bazzoni G.

Int J Dev Biol. 2000;44(6):743-8. Review.

32.

The role of endothelial cell-to-cell junctions in vascular morphogenesis.

Dejana E, Bazzoni G, Lampugnani MG.

Thromb Haemost. 1999 Aug;82(2):755-61. Review. No abstract available.

PMID:
10605779
33.

Histamine induces tyrosine phosphorylation of endothelial cell-to-cell adherens junctions.

Andriopoulou P, Navarro P, Zanetti A, Lampugnani MG, Dejana E.

Arterioscler Thromb Vasc Biol. 1999 Oct;19(10):2286-97.

PMID:
10521356
34.

Endothelial adhesion molecules in the development of the vascular tree: the garden of forking paths.

Bazzoni G, Dejana E, Lampugnani MG.

Curr Opin Cell Biol. 1999 Oct;11(5):573-81. Review.

PMID:
10508655
35.

Vascular endothelial (VE)-cadherin: only an intercellular glue?

Dejana E, Bazzoni G, Lampugnani MG.

Exp Cell Res. 1999 Oct 10;252(1):13-9. Review.

PMID:
10502395
36.

Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo.

Corada M, Mariotti M, Thurston G, Smith K, Kunkel R, Brockhaus M, Lampugnani MG, Martin-Padura I, Stoppacciaro A, Ruco L, McDonald DM, Ward PA, Dejana E.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9815-20.

37.

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.

Carmeliet P, Lampugnani MG, Moons L, Breviario F, Compernolle V, Bono F, Balconi G, Spagnuolo R, Oosthuyse B, Dewerchin M, Zanetti A, Angellilo A, Mattot V, Nuyens D, Lutgens E, Clotman F, de Ruiter MC, Gittenberger-de Groot A, Poelmann R, Lupu F, Herbert JM, Collen D, Dejana E.

Cell. 1999 Jul 23;98(2):147-57.

38.

Cell migration into a wounded area in vitro.

Lampugnani MG.

Methods Mol Biol. 1999;96:177-82. Review. No abstract available.

PMID:
10098136
39.

Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells.

Esser S, Lampugnani MG, Corada M, Dejana E, Risau W.

J Cell Sci. 1998 Jul;111 ( Pt 13):1853-65.

40.

Interendothelial junctions: structure, signalling and functional roles.

Lampugnani MG, Dejana E.

Curr Opin Cell Biol. 1997 Oct;9(5):674-82. Review.

PMID:
9330871
41.

Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells.

Lampugnani MG, Corada M, Andriopoulou P, Esser S, Risau W, Dejana E.

J Cell Sci. 1997 Sep;110 ( Pt 17):2065-77.

42.

Intercellular junctions in the endothelium and the control of vascular permeability.

Dejana E, Valiron O, Navarro P, Lampugnani MG.

Ann N Y Acad Sci. 1997 Apr 15;811:36-43; discussion 43-4. Review. No abstract available.

PMID:
9186582
43.

Polymorphonuclear leukocyte adhesion triggers the disorganization of endothelial cell-to-cell adherens junctions.

Del Maschio A, Zanetti A, Corada M, Rival Y, Ruco L, Lampugnani MG, Dejana E.

J Cell Biol. 1996 Oct;135(2):497-510.

44.

Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin).

Caveda L, Martin-Padura I, Navarro P, Breviario F, Corada M, Gulino D, Lampugnani MG, Dejana E.

J Clin Invest. 1996 Aug 15;98(4):886-93.

45.

Thrombin-induced increase in endothelial permeability is associated with changes in cell-to-cell junction organization.

Rabiet MJ, Plantier JL, Rival Y, Genoux Y, Lampugnani MG, Dejana E.

Arterioscler Thromb Vasc Biol. 1996 Mar;16(3):488-96.

PMID:
8630677
46.

Catenin-dependent and -independent functions of vascular endothelial cadherin.

Navarro P, Caveda L, Breviario F, Mândoteanu I, Lampugnani MG, Dejana E.

J Biol Chem. 1995 Dec 29;270(52):30965-72.

47.

Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin.

Breviario F, Caveda L, Corada M, Martin-Padura I, Navarro P, Golay J, Introna M, Gulino D, Lampugnani MG, Dejana E.

Arterioscler Thromb Vasc Biol. 1995 Aug;15(8):1229-39.

PMID:
7627717
48.

Endothelial cell-to-cell junctions.

Dejana E, Corada M, Lampugnani MG.

FASEB J. 1995 Jul;9(10):910-8. Review.

PMID:
7615160
49.
50.

Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells.

Ayalon O, Sabanai H, Lampugnani MG, Dejana E, Geiger B.

J Cell Biol. 1994 Jul;126(1):247-58.

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