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Items: 38

1.

Microsatellite instability in gastric cancer: molecular bases, clinical perspectives, and new treatment approaches.

Ratti M, Lampis A, Hahne JC, Passalacqua R, Valeri N.

Cell Mol Life Sci. 2018 Nov;75(22):4151-4162. doi: 10.1007/s00018-018-2906-9. Epub 2018 Sep 1. Review.

PMID:
30173350
2.

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial.

Khan KH, Cunningham D, Werner B, Vlachogiannis G, Spiteri I, Heide T, Mateos JF, Vatsiou A, Lampis A, Damavandi MD, Lote H, Huntingford IS, Hedayat S, Chau I, Tunariu N, Mentrasti G, Trevisani F, Rao S, Anandappa G, Watkins D, Starling N, Thomas J, Peckitt C, Khan N, Rugge M, Begum R, Hezelova B, Bryant A, Jones T, Proszek P, Fassan M, Hahne JC, Hubank M, Braconi C, Sottoriva A, Valeri N.

Cancer Discov. 2018 Oct;8(10):1270-1285. doi: 10.1158/2159-8290.CD-17-0891. Epub 2018 Aug 30.

PMID:
30166348
3.

Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma.

Mensah AA, Cascione L, Gaudio E, Tarantelli C, Bomben R, Bernasconi E, Zito D, Lampis A, Hahne JC, Rinaldi A, Stathis A, Zucca E, Kwee I, Gattei V, Valeri N, Riveiro ME, Bertoni F.

Haematologica. 2018 Aug 3. pii: haematol.2018.191684. doi: 10.3324/haematol.2018.191684. [Epub ahead of print]

4.

MicroRNAs as Mediators of Resistance Mechanisms to Small-Molecule Tyrosine Kinase Inhibitors in Solid Tumours.

Ghidini M, Hahne JC, Frizziero M, Tomasello G, Trevisani F, Lampis A, Passalacqua R, Valeri N.

Target Oncol. 2018 Aug;13(4):423-436. doi: 10.1007/s11523-018-0580-3.

PMID:
30006826
5.

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.

Vlachogiannis G, Hedayat S, Vatsiou A, Jamin Y, Fernández-Mateos J, Khan K, Lampis A, Eason K, Huntingford I, Burke R, Rata M, Koh DM, Tunariu N, Collins D, Hulkki-Wilson S, Ragulan C, Spiteri I, Moorcraft SY, Chau I, Rao S, Watkins D, Fotiadis N, Bali M, Darvish-Damavandi M, Lote H, Eltahir Z, Smyth EC, Begum R, Clarke PA, Hahne JC, Dowsett M, de Bono J, Workman P, Sadanandam A, Fassan M, Sansom OJ, Eccles S, Starling N, Braconi C, Sottoriva A, Robinson SP, Cunningham D, Valeri N.

Science. 2018 Feb 23;359(6378):920-926. doi: 10.1126/science.aao2774.

6.

KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer.

Sclafani F, Chau I, Cunningham D, Hahne JC, Vlachogiannis G, Eltahir Z, Lampis A, Braconi C, Kalaitzaki E, De Castro DG, Wotherspoon A, Capdevila J, Glimelius B, Tarazona N, Begum R, Lote H, Hulkki Wilson S, Mentrasti G, Brown G, Tait D, Oates J, Valeri N.

Sci Rep. 2018 Jan 23;8(1):1445. doi: 10.1038/s41598-018-19212-5.

7.

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma.

Lampis A, Carotenuto P, Vlachogiannis G, Cascione L, Hedayat S, Burke R, Clarke P, Bosma E, Simbolo M, Scarpa A, Yu S, Cole R, Smyth E, Mateos JF, Begum R, Hezelova B, Eltahir Z, Wotherspoon A, Fotiadis N, Bali MA, Nepal C, Khan K, Stubbs M, Hahne JC, Gasparini P, Guzzardo V, Croce CM, Eccles S, Fassan M, Cunningham D, Andersen JB, Workman P, Valeri N, Braconi C.

Gastroenterology. 2018 Mar;154(4):1066-1079.e5. doi: 10.1053/j.gastro.2017.10.043. Epub 2017 Nov 4.

8.

Characterisation of the immune-related transcriptome in resected biliary tract cancers.

Ghidini M, Cascione L, Carotenuto P, Lampis A, Trevisani F, Previdi MC, Hahne JC, Said-Huntingford I, Raj M, Zerbi A, Mescoli C, Cillo U, Rugge M, Roncalli M, Torzilli G, Rimassa L, Santoro A, Valeri N, Fassan M, Braconi C.

Eur J Cancer. 2017 Nov;86:158-165. doi: 10.1016/j.ejca.2017.09.005. Epub 2017 Oct 6.

9.

Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study.

Khan K, Rata M, Cunningham D, Koh DM, Tunariu N, Hahne JC, Vlachogiannis G, Hedayat S, Marchetti S, Lampis A, Damavandi MD, Lote H, Rana I, Williams A, Eccles SA, Fontana E, Collins D, Eltahir Z, Rao S, Watkins D, Starling N, Thomas J, Kalaitzaki E, Fotiadis N, Begum R, Bali M, Rugge M, Temple E, Fassan M, Chau I, Braconi C, Valeri N.

Gut. 2018 Aug;67(8):1484-1492. doi: 10.1136/gutjnl-2017-314178. Epub 2017 Aug 8.

10.

Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer.

Lote H, Spiteri I, Ermini L, Vatsiou A, Roy A, McDonald A, Maka N, Balsitis M, Bose N, Simbolo M, Mafficini A, Lampis A, Hahne JC, Trevisani F, Eltahir Z, Mentrasti G, Findlay C, Kalkman EAJ, Punta M, Werner B, Lise S, Aktipis A, Maley C, Greaves M, Braconi C, White J, Fassan M, Scarpa A, Sottoriva A, Valeri N.

Ann Oncol. 2017 Jun 1;28(6):1243-1249. doi: 10.1093/annonc/mdx074.

11.

MicroRNA 193b-3p as a predictive biomarker of chronic kidney disease in patients undergoing radical nephrectomy for renal cell carcinoma.

Trevisani F, Ghidini M, Larcher A, Lampis A, Lote H, Manunta P, Alibrandi MT, Zagato L, Citterio L, Dell'Antonio G, Carenzi C, Capasso G, Rugge M, Rigotti P, Bertini R, Cascione L, Briganti A, Salonia A, Benigni F, Braconi C, Fassan M, Hahne JC, Montorsi F, Valeri N.

Br J Cancer. 2016 Nov 22;115(11):1343-1350. doi: 10.1038/bjc.2016.329. Epub 2016 Nov 1.

12.

Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers.

Carotenuto P, Fassan M, Pandolfo R, Lampis A, Vicentini C, Cascione L, Paulus-Hock V, Boulter L, Guest R, Quagliata L, Hahne JC, Ridgway R, Jamieson T, Athineos D, Veronese A, Visone R, Murgia C, Ferrari G, Guzzardo V, Evans TRJ, MacLeod M, Feng GJ, Dale T, Negrini M, Forbes SJ, Terracciano L, Scarpa A, Patel T, Valeri N, Workman P, Sansom O, Braconi C.

Gut. 2017 Jul;66(7):1268-1277. doi: 10.1136/gutjnl-2016-312278. Epub 2016 Sep 12.

13.

Coherent control of group index and magneto-optical anisotropy in a multilevel atomic vapor.

Lampis A, Culver R, Megyeri B, Goldwin J.

Opt Express. 2016 Jul 11;24(14):15494-505. doi: 10.1364/OE.24.015494.

PMID:
27410824
14.

Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients.

Sclafani F, Chau I, Cunningham D, Lampis A, Hahne JC, Ghidini M, Lote H, Zito D, Tabernero J, Glimelius B, Cervantes A, Begum R, De Castro DG, Wilson SH, Peckitt C, Eltahir Z, Wotherspoon A, Tait D, Brown G, Oates J, Braconi C, Valeri N.

Carcinogenesis. 2016 Sep;37(9):852-7. doi: 10.1093/carcin/bgw073. Epub 2016 Jul 5.

15.

Effect of Pathologic Tumor Response and Nodal Status on Survival in the Medical Research Council Adjuvant Gastric Infusional Chemotherapy Trial.

Smyth EC, Fassan M, Cunningham D, Allum WH, Okines AF, Lampis A, Hahne JC, Rugge M, Peckitt C, Nankivell M, Langley R, Ghidini M, Braconi C, Wotherspoon A, Grabsch HI, Valeri N.

J Clin Oncol. 2016 Aug 10;34(23):2721-7. doi: 10.1200/JCO.2015.65.7692. Epub 2016 Jun 13.

16.

Prognostic role of the LCS6 KRAS variant in locally advanced rectal cancer: results of the EXPERT-C trial.

Sclafani F, Chau I, Cunningham D, Peckitt C, Lampis A, Hahne JC, Braconi C, Tabernero J, Glimelius B, Cervantes A, Begum R, Gonzalez De Castro D, Hulkki Wilson S, Eltahir Z, Wotherspoon A, Tait D, Brown G, Oates J, Valeri N.

Ann Oncol. 2015 Sep;26(9):1936-41. doi: 10.1093/annonc/mdv285. Epub 2015 Jul 10.

17.

BRAF mutation analysis is a valid tool to implement in Lynch syndrome diagnosis in patients classified according to the Bethesda guidelines.

Molinari F, Signoroni S, Lampis A, Bertan C, Perrone F, Sala P, Mondini P, Crippa S, Bertario L, Frattini M.

Tumori. 2014 May-Jun;100(3):315-20. doi: 10.1700/1578.17214.

PMID:
25076244
18.

Circulating free DNA in a screening program for early colorectal cancer detection.

Perrone F, Lampis A, Bertan C, Verderio P, Ciniselli CM, Pizzamiglio S, Frattini M, Nucifora M, Molinari F, Gallino G, Gariboldi M, Meroni E, Leo E, Pierotti MA, Pilotti S.

Tumori. 2014 Mar-Apr;100(2):115-21. doi: 10.1700/1491.16389.

PMID:
24852853
19.

MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.

Valeri N, Braconi C, Gasparini P, Murgia C, Lampis A, Paulus-Hock V, Hart JR, Ueno L, Grivennikov SI, Lovat F, Paone A, Cascione L, Sumani KM, Veronese A, Fabbri M, Carasi S, Alder H, Lanza G, Gafa' R, Moyer MP, Ridgway RA, Cordero J, Nuovo GJ, Frankel WL, Rugge M, Fassan M, Groden J, Vogt PK, Karin M, Sansom OJ, Croce CM.

Cancer Cell. 2014 Apr 14;25(4):469-83. doi: 10.1016/j.ccr.2014.03.006.

20.

Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: Clinical outcome and biomarkers of efficacy.

Pietrantonio F, Perrone F, Biondani P, Maggi C, Lampis A, Bertan C, Venturini F, Tondulli L, Ferrari D, Ricci V, Villa F, Barone G, Bianco N, Ghidini A, Bossi I, Fanetti G, Di Bartolomeo M, de Braud F.

Cancer Biol Ther. 2013 Dec;14(12):1098-103. doi: 10.4161/cbt.26343. Epub 2013 Sep 4.

21.

Lack of KRAS, NRAS, BRAF and TP53 mutations improves outcome of elderly metastatic colorectal cancer patients treated with cetuximab, oxaliplatin and UFT.

Di Bartolomeo M, Pietrantonio F, Perrone F, Dotti KF, Lampis A, Bertan C, Beretta E, Rimassa L, Carbone C, Biondani P, Passalacqua R, Pilotti S, Bajetta E; Italian Trials in Medical Oncology Group.

Target Oncol. 2014 Jun;9(2):155-62. doi: 10.1007/s11523-013-0283-8. Epub 2013 Jul 3.

PMID:
23821376
22.

miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation.

Reid JF, Sokolova V, Zoni E, Lampis A, Pizzamiglio S, Bertan C, Zanutto S, Perrone F, Camerini T, Gallino G, Verderio P, Leo E, Pilotti S, Gariboldi M, Pierotti MA.

Mol Cancer Res. 2012 Apr;10(4):504-15. doi: 10.1158/1541-7786.MCR-11-0342. Epub 2012 Feb 16.

23.

Methylation status in patients with early stage colon cancer: a new prognostic marker?

Zanutto S, Pizzamiglio S, Lampis A, Camerini T, Di Mauro MG, Pierotti MA, Verderio P, Gariboldi M.

Int J Cancer. 2012 Jan 15;130(2):488-9. doi: 10.1002/ijc.26011. Epub 2011 Apr 25. No abstract available.

24.

Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle.

Bhoori S, Toffanin S, Sposito C, Germini A, Pellegrinelli A, Lampis A, Mazzaferro V.

J Hepatol. 2010 May;52(5):771-5. doi: 10.1016/j.jhep.2010.01.025. Epub 2010 Mar 4.

25.

Integrative approach for prioritizing cancer genes in sporadic colon cancer.

Reid JF, Gariboldi M, Sokolova V, Capobianco P, Lampis A, Perrone F, Signoroni S, Costa A, Leo E, Pilotti S, Pierotti MA.

Genes Chromosomes Cancer. 2009 Nov;48(11):953-62. doi: 10.1002/gcc.20697.

PMID:
19672874
26.
27.

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients.

Perrone F, Lampis A, Orsenigo M, Di Bartolomeo M, Gevorgyan A, Losa M, Frattini M, Riva C, Andreola S, Bajetta E, Bertario L, Leo E, Pierotti MA, Pilotti S.

Ann Oncol. 2009 Jan;20(1):84-90. doi: 10.1093/annonc/mdn541. Epub 2008 Jul 31.

PMID:
18669866
28.

Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation.

Bozzi F, Ferrari A, Negri T, Conca E, Luca da R, Losa M, Casieri P, Orsenigo M, Lampis A, Meazza C, Casanova M, Pierotti MA, Tamborini E, Pilotti S.

Transl Oncol. 2008 Jul;1(2):95-101.

29.

Pulsatile secretion of thyrotropin in children.

Loche S, Cherubini V, Bartolotta E, Lampis A, Carta D, Tomasi P, Pintor C.

J Endocrinol Invest. 1994 Mar;17(3):189-93.

PMID:
8051341
30.

Growth hormone response to oral clonidine test in normal and short children.

Loche S, Cappa M, Ghigo E, Faedda A, Lampis A, Carta D, Pintor C.

J Endocrinol Invest. 1993 Dec;16(11):899-902.

PMID:
8144867
31.

The effect of short-term growth hormone or low-dose oxandrolone treatment in boys with constitutional growth delay.

Loche S, Pintor C, Cambiaso P, Lampis A, Carta D, Corda R, Cappa M.

J Endocrinol Invest. 1991 Oct;14(9):747-50.

PMID:
1761810
32.

High-energy gamma-ray production in the heavy-ion reaction 136Xe + Sn at E/A=89 and 124 MeV.

Clayton J, Stevenson J, Benenson W, Chen Y, Kashy E, Lampis AR, Samuel M, Tam CL, Mohar MF, Morrissey DJ, Murakami TK, Sherrill B, Winfield JS.

Phys Rev C Nucl Phys. 1989 Sep;40(3):1207-1212. No abstract available.

PMID:
9966094
33.

Mass dependence of high-energy gamma-ray production in heavy-ion reactions.

Tam CL, Stevenson J, Benenson W, Clayton J, Chen Y, Kashy E, Lampis AR, Morrissey DJ, Samuel M, Murakami TK, Winfield JS.

Phys Rev C Nucl Phys. 1989 Apr;39(4):1371-1376. No abstract available.

PMID:
9955344
34.

High-energy gamma-ray production in light-ion induced reactions.

Tam CL, Stevenson J, Benenson W, Clayton J, Chen Y, Kashy E, Lampis AR, Morrissey DJ, Samuel M, Murakami TK, Winfield JS.

Phys Rev C Nucl Phys. 1988 Dec;38(6):2526-2530. No abstract available.

PMID:
9955095
35.

Clonidine treatment in children with short stature.

Loche S, Lampis A, Cella SG, Locatelli V, Müller EE, Pintor C.

J Endocrinol Invest. 1988 Nov;11(10):763-7. Review. No abstract available.

PMID:
3068294
36.

Correlations between high energy gamma rays and light fragments in heavy ion collisions.

Lampis AR, Stevenson J, Benenson W, Clayton J, Cebra D, Chen Y, Fox D, Kashy E, Morrissey DJ, Samuel M, Smith R, Tam CL, Westfall GD, Wilson K, Winfield JS.

Phys Rev C Nucl Phys. 1988 Oct;38(4):1961-1964. No abstract available.

PMID:
9955013
37.

High-energy gamma-ray emission in heavy-ion collisions.

Stevenson J, Beard KB, Benenson W, Clayton J, Kashy E, Lampis A, Morrissey DJ, Samuel M, Smith RJ, Tam CL, Winfield JS.

Phys Rev Lett. 1986 Aug 4;57(5):555-558. No abstract available.

PMID:
10034092
38.

The effect of oxandrolone on the growth hormone response to growth hormone releasing hormone in children with constitutional growth delay.

Loche S, Corda R, Lampis A, Puggioni R, Cella SG, Muller EE, Pintor C.

Clin Endocrinol (Oxf). 1986 Aug;25(2):195-200.

PMID:
3098462

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