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Items: 1 to 50 of 152

1.

Plasma metabolomics profiles suggest beneficial effects of a low-glycemic load dietary pattern on inflammation and energy metabolism.

Navarro SL, Tarkhan A, Shojaie A, Randolph TW, Gu H, Djukovic D, Osterbauer KJ, Hullar MA, Kratz M, Neuhouser ML, Lampe PD, Raftery D, Lampe JW.

Am J Clin Nutr. 2019 Aug 20. pii: nqz169. doi: 10.1093/ajcn/nqz169. [Epub ahead of print]

PMID:
31432072
2.

Connexin 43 Functions as a Positive Regulator of Stem Cell Differentiation into Definitive Endoderm and Pancreatic Progenitors.

Yang W, Lampe PD, Kensel-Hammes P, Hesson J, Ware CB, Crisa L, Cirulli V.

iScience. 2019 Jul 24;19:450-460. doi: 10.1016/j.isci.2019.07.033. [Epub ahead of print]

3.

Phosphorylation of connexin43 at MAPK, PKC or CK1 sites each distinctly alter the kinetics of epidermal wound repair.

Lastwika KJ, Dunn CA, Solan JL, Lampe PD.

J Cell Sci. 2019 Aug 19. pii: jcs.234633. doi: 10.1242/jcs.234633. [Epub ahead of print]

PMID:
31427427
4.

The lipidated connexin mimetic peptide, SRPTEKT-Hdc, is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform.

Cotter ML, Boitano S, Lampe PD, Solan JL, Vagner J, Ek-Vitorin JF, Burt JM.

Am J Physiol Cell Physiol. 2019 Jul 31. doi: 10.1152/ajpcell.00160.2019. [Epub ahead of print]

PMID:
31365296
5.

Proteomic Analysis of Plasma Reveals Fat Mass Influences Cancer-Related Pathways in Healthy Humans Fed Controlled Diets Differing in Glycemic Load.

Garrison CB, Zhang Y, Navarro SL, Randolph TW, Hullar MAJ, Kratz M, Neuhouser ML, Raftery D, Lampe PD, Lampe JW.

Cancer Prev Res (Phila). 2019 Sep;12(9):567-578. doi: 10.1158/1940-6207.CAPR-19-0175. Epub 2019 Jul 2.

PMID:
31266826
6.

Cx43 phosphorylation-mediated effects on ERK and Akt protect against ischemia reperfusion injury and alter the stability of the stress-inducible protein NDRG1.

Solan JL, Márquez-Rosado L, Lampe PD.

J Biol Chem. 2019 Aug 2;294(31):11762-11771. doi: 10.1074/jbc.RA119.009162. Epub 2019 Jun 12.

PMID:
31189653
7.

Comparison of prediction models with radiological semantic features and radiomics in lung cancer diagnosis of the pulmonary nodules: a case-control study.

Wu W, Pierce LA, Zhang Y, Pipavath SNJ, Randolph TW, Lastwika KJ, Lampe PD, Houghton AM, Liu H, Xia L, Kinahan PE.

Eur Radiol. 2019 May 21. doi: 10.1007/s00330-019-06213-9. [Epub ahead of print]

PMID:
31115618
8.

Targeting MAPK phosphorylation of Connexin43 provides neuroprotection in stroke.

Freitas-Andrade M, Wang N, Bechberger JF, De Bock M, Lampe PD, Leybaert L, Naus CC.

J Exp Med. 2019 Apr 1;216(4):916-935. doi: 10.1084/jem.20171452. Epub 2019 Mar 14.

PMID:
30872361
9.

Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane.

DeLalio LJ, Billaud M, Ruddiman CA, Johnstone SR, Butcher JT, Wolpe AG, Jin X, Keller TCS 4th, Keller AS, Rivière T, Good ME, Best AK, Lohman AW, Swayne LA, Penuela S, Thompson RJ, Lampe PD, Yeager M, Isakson BE.

J Biol Chem. 2019 Apr 26;294(17):6940-6956. doi: 10.1074/jbc.RA118.006982. Epub 2019 Feb 27.

PMID:
30814251
10.

Differences in serum biomarkers between combined glucosamine and chondroitin versus celecoxib in a randomized, double-blind trial in osteoarthritis patients.

Navarro SL, Herrero M, Martinez H, Zhang Y, Ladd J, Lo E, Shelley D, Randolph TW, Lampe JW, Lampe PD.

Antiinflamm Antiallergy Agents Med Chem. 2019 Jan 14. doi: 10.2174/1871523018666190115094512. [Epub ahead of print]

PMID:
30648524
11.

Tumor-derived Autoantibodies Identify Malignant Pulmonary Nodules.

Lastwika KJ, Kargl J, Zhang Y, Zhu X, Lo E, Shelley D, Ladd JJ, Wu W, Kinahan P, Pipavath SNJ, Randolph TW, Shipley M, Lampe PD, Houghton AM.

Am J Respir Crit Care Med. 2019 May 15;199(10):1257-1266. doi: 10.1164/rccm.201804-0628OC.

PMID:
30422669
12.

Therapeutic strategies targeting connexins.

Laird DW, Lampe PD.

Nat Rev Drug Discov. 2018 Dec;17(12):905-921. doi: 10.1038/nrd.2018.138. Epub 2018 Oct 12. Review.

13.

Implications of Epigenetic Drift in Colorectal Neoplasia.

Luebeck GE, Hazelton WD, Curtius K, Maden SK, Yu M, Carter KT, Burke W, Lampe PD, Li CI, Ulrich CM, Newcomb PA, Westerhoff M, Kaz AM, Luo Y, Inadomi JM, Grady WM.

Cancer Res. 2019 Feb 1;79(3):495-504. doi: 10.1158/0008-5472.CAN-18-1682. Epub 2018 Oct 5.

PMID:
30291105
14.

Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43.

Kam CY, Dubash AD, Magistrati E, Polo S, Satchell KJF, Sheikh F, Lampe PD, Green KJ.

J Cell Biol. 2018 Sep 3;217(9):3219-3235. doi: 10.1083/jcb.201710161. Epub 2018 Jun 29.

15.

Suppression of connexin 43 phosphorylation promotes astrocyte survival and vascular regeneration in proliferative retinopathy.

Slavi N, Toychiev AH, Kosmidis S, Ackert J, Bloomfield SA, Wulff H, Viswanathan S, Lampe PD, Srinivas M.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5934-E5943. doi: 10.1073/pnas.1803907115. Epub 2018 Jun 11.

16.

Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study.

Ginos BNR, Navarro SL, Schwarz Y, Gu H, Wang D, Randolph TW, Shojaie A, Hullar MAJ, Lampe PD, Kratz M, Neuhouser ML, Raftery D, Lampe JW.

Metabolism. 2018 Jun;83:197-204. doi: 10.1016/j.metabol.2018.02.006. Epub 2018 Feb 17.

17.

Newly Identified NO-Sensor Guanylyl Cyclase/Connexin 43 Association Is Involved in Cardiac Electrical Function.

Crassous PA, Shu P, Huang C, Gordan R, Brouckaert P, Lampe PD, Xie LH, Beuve A.

J Am Heart Assoc. 2017 Dec 21;6(12). pii: e006397. doi: 10.1161/JAHA.117.006397.

18.

Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications.

Leybaert L, Lampe PD, Dhein S, Kwak BR, Ferdinandy P, Beyer EC, Laird DW, Naus CC, Green CR, Schulz R.

Pharmacol Rev. 2017 Oct;69(4):396-478. doi: 10.1124/pr.115.012062. Review.

19.

SnapShot: Connexins and Disease.

Laird DW, Naus CC, Lampe PD.

Cell. 2017 Sep 7;170(6):1260-1260.e1. doi: 10.1016/j.cell.2017.08.034.

20.

Regulation of Cx37 channel and growth-suppressive properties by phosphorylation.

Jacobsen NL, Pontifex TK, Li H, Solan JL, Lampe PD, Sorgen PL, Burt JM.

J Cell Sci. 2017 Oct 1;130(19):3308-3321. doi: 10.1242/jcs.202572. Epub 2017 Aug 17.

21.

Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets.

Miles FL, Navarro SL, Schwarz Y, Gu H, Djukovic D, Randolph TW, Shojaie A, Kratz M, Hullar MAJ, Lampe PD, Neuhouser ML, Raftery D, Lampe JW.

Food Funct. 2017 Sep 20;8(9):3209-3218. doi: 10.1039/c7fo00684e.

22.

Gap junctions and cancer: communicating for 50 years.

Aasen T, Mesnil M, Naus CC, Lampe PD, Laird DW.

Nat Rev Cancer. 2017 Jan;17(1):74. doi: 10.1038/nrc.2016.142. Epub 2016 Dec 2. No abstract available.

PMID:
28704356
23.

An update on minding the gap in cancer.

Mesnil M, Aasen T, Boucher J, Chépied A, Cronier L, Defamie N, Kameritsch P, Laird DW, Lampe PD, Lathia JD, Leithe E, Mehta PP, Monvoisin A, Pogoda K, Sin WC, Tabernero A, Yamasaki H, Yeh ES, Dagli MLZ, Naus CC.

Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):237-243. doi: 10.1016/j.bbamem.2017.06.015. Epub 2017 Jun 24. Review.

24.

Exploratory plasma proteomic analysis in a randomized crossover trial of aspirin among healthy men and women.

Wang X, Shojaie A, Zhang Y, Shelley D, Lampe PD, Levy L, Peters U, Potter JD, White E, Lampe JW.

PLoS One. 2017 May 25;12(5):e0178444. doi: 10.1371/journal.pone.0178444. eCollection 2017.

25.

Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics.

Solan JL, Lampe PD.

Biochim Biophys Acta Biomembr. 2018 Jan;1860(1):83-90. doi: 10.1016/j.bbamem.2017.04.008. Epub 2017 Apr 13. Review.

26.

Protein and glycomic plasma markers for early detection of adenoma and colon cancer.

Rho JH, Ladd JJ, Li CI, Potter JD, Zhang Y, Shelley D, Shibata D, Coppola D, Yamada H, Toyoda H, Tada T, Kumada T, Brenner DE, Hanash SM, Lampe PD.

Gut. 2018 Mar;67(3):473-484. doi: 10.1136/gutjnl-2016-312794. Epub 2016 Nov 7.

27.

Gap junctions and cancer: communicating for 50 years.

Aasen T, Mesnil M, Naus CC, Lampe PD, Laird DW.

Nat Rev Cancer. 2016 Dec;16(12):775-788. doi: 10.1038/nrc.2016.105. Epub 2016 Oct 21. Review. Erratum in: Nat Rev Cancer. 2017 Jan;17 (1):74.

28.

Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections with Obesity.

Garrison CB, Lastwika KJ, Zhang Y, Li CI, Lampe PD.

J Proteome Res. 2017 Jan 6;16(1):274-287. doi: 10.1021/acs.jproteome.6b00611. Epub 2016 Nov 14.

29.

Regulation of gap junction conductance by calcineurin through Cx43 phosphorylation: implications for action potential conduction.

Jabr RI, Hatch FS, Salvage SC, Orlowski A, Lampe PD, Fry CH.

Pflugers Arch. 2016 Nov;468(11-12):1945-1955. Epub 2016 Oct 19.

30.

Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study.

Böhm J, Pianka F, Stüttgen N, Rho J, Gigic B, Zhang Y, Habermann N, Schrotz-King P, Abbenhardt-Martin C, Zielske L, Lampe PD, Ulrich A, Diener MK, Ulrich CM.

Surgery. 2017 Mar;161(3):808-817. doi: 10.1016/j.surg.2016.08.025. Epub 2016 Oct 13.

31.

Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis.

Egbert JR, Uliasz TF, Shuhaibar LC, Geerts A, Wunder F, Kleiman RJ, Humphrey JM, Lampe PD, Artemyev NO, Rybalkin SD, Beavo JA, Movsesian MA, Jaffe LA.

Biol Reprod. 2016 May;94(5):110. doi: 10.1095/biolreprod.115.135897. Epub 2016 Mar 23.

32.

Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism.

Puebla C, Cisterna BA, Salas DP, Delgado-López F, Lampe PD, Sáez JC.

Biochim Biophys Acta. 2016 May;1861(5):439-48. doi: 10.1016/j.bbalip.2016.02.002. Epub 2016 Feb 8.

33.

Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43.

Morel S, Christoffersen C, Axelsen LN, Montecucco F, Rochemont V, Frias MA, Mach F, James RW, Naus CC, Chanson M, Lampe PD, Nielsen MS, Nielsen LB, Kwak BR.

Cardiovasc Res. 2016 Mar 1;109(3):385-96. doi: 10.1093/cvr/cvw004. Epub 2016 Jan 13.

34.

Kinase programs spatiotemporally regulate gap junction assembly and disassembly: Effects on wound repair.

Solan JL, Lampe PD.

Semin Cell Dev Biol. 2016 Feb;50:40-8. doi: 10.1016/j.semcdb.2015.12.010. Epub 2015 Dec 17. Review.

35.

Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.

Thomas SS, Makar KW, Li L, Zheng Y, Yang P, Levy L, Rudolph RY, Lampe PD, Yan M, Markowitz SD, Bigler J, Lampe JW, Potter JD.

Genom Data. 2015 Sep 1;6:154-8. doi: 10.1016/j.gdata.2015.08.029. eCollection 2015 Dec.

36.

Mitogen-activated Protein Kinase (MAPK) Activated by Prostaglandin E2 Phosphorylates Connexin 43 and Closes Osteocytic Hemichannels in Response to Continuous Flow Shear Stress.

Riquelme MA, Burra S, Kar R, Lampe PD, Jiang JX.

J Biol Chem. 2015 Nov 20;290(47):28321-8. doi: 10.1074/jbc.M115.683417. Epub 2015 Oct 6.

37.

MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas.

Taguchi A, Rho JH, Yan Q, Zhang Y, Zhao Y, Xu H, Tripathi SC, Wang H, Brenner DE, Kucherlapati M, Kucherlapati R, Boutin AT, Wang YA, DePinho RA, Feng Z, Lampe PD, Hanash SM.

Cancer Prev Res (Phila). 2015 Nov;8(11):1112-9. doi: 10.1158/1940-6207.CAPR-15-0077. Epub 2015 Sep 4.

38.

CELLULAR SMALL TALK.

Laird DW, Lampe PD, Johnson RG.

Sci Am. 2015 May;312(5):70-7. No abstract available.

PMID:
26336714
39.

Candidate early detection protein biomarkers for ER+/PR+ invasive ductal breast carcinoma identified using pre-clinical plasma from the WHI observational study.

Buas MF, Rho JH, Chai X, Zhang Y, Lampe PD, Li CI.

Breast Cancer Res Treat. 2015 Sep;153(2):445-54. doi: 10.1007/s10549-015-3554-5. Epub 2015 Aug 30.

40.

Acetylation mediates Cx43 reduction caused by electrical stimulation.

Meraviglia V, Azzimato V, Colussi C, Florio MC, Binda A, Panariti A, Qanud K, Suffredini S, Gennaccaro L, Miragoli M, Barbuti A, Lampe PD, Gaetano C, Pramstaller PP, Capogrossi MC, Recchia FA, Pompilio G, Rivolta I, Rossini A.

J Mol Cell Cardiol. 2015 Oct;87:54-64. doi: 10.1016/j.yjmcc.2015.08.001. Epub 2015 Aug 8.

41.

Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection.

Schulz R, Görge PM, Görbe A, Ferdinandy P, Lampe PD, Leybaert L.

Pharmacol Ther. 2015 Sep;153:90-106. doi: 10.1016/j.pharmthera.2015.06.005. Epub 2015 Jun 11. Review.

42.

Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.

Thomas SS, Makar KW, Li L, Zheng Y, Yang P, Levy L, Rudolph RY, Lampe PD, Yan M, Markowitz SD, Bigler J, Lampe JW, Potter JD.

BMC Med Genet. 2015 Mar 24;16:18. doi: 10.1186/s12881-015-0161-6.

43.

Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition.

Salas D, Puebla C, Lampe PD, Lavandero S, Sáez JC.

Biochim Biophys Acta. 2015 Jul;1852(7):1268-77. doi: 10.1016/j.bbadis.2015.03.004. Epub 2015 Mar 14.

44.

Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles.

Shuhaibar LC, Egbert JR, Norris RP, Lampe PD, Nikolaev VO, Thunemann M, Wen L, Feil R, Jaffe LA.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5527-32. doi: 10.1073/pnas.1423598112. Epub 2015 Mar 16.

45.

Randomized trial of glucosamine and chondroitin supplementation on inflammation and oxidative stress biomarkers and plasma proteomics profiles in healthy humans.

Navarro SL, White E, Kantor ED, Zhang Y, Rho J, Song X, Milne GL, Lampe PD, Lampe JW.

PLoS One. 2015 Feb 26;10(2):e0117534. doi: 10.1371/journal.pone.0117534. eCollection 2015.

46.

Cross-species antibody microarray interrogation identifies a 3-protein panel of plasma biomarkers for early diagnosis of pancreas cancer.

Mirus JE, Zhang Y, Li CI, Lokshin AE, Prentice RL, Hingorani SR, Lampe PD.

Clin Cancer Res. 2015 Apr 1;21(7):1764-71. doi: 10.1158/1078-0432.CCR-13-3474. Epub 2015 Jan 14.

47.

Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease.

Mirus JE, Zhang Y, Hollingsworth MA, Solan JL, Lampe PD, Hingorani SR.

Mol Cell Proteomics. 2014 Dec;13(12):3484-96. doi: 10.1074/mcp.M113.036517. Epub 2014 Sep 15.

48.

Gap junction regulation of vascular tone: implications of modulatory intercellular communication during gestation.

Ampey BC, Morschauser TJ, Lampe PD, Magness RR.

Adv Exp Med Biol. 2014;814:117-32. doi: 10.1007/978-1-4939-1031-1_11. Review.

49.

Dermcidin expression is associated with disease progression and survival among breast cancer patients.

Brauer HA, D'Arcy M, Libby TE, Thompson HJ, Yasui YY, Hamajima N, Li CI, Troester MA, Lampe PD.

Breast Cancer Res Treat. 2014 Apr;144(2):299-306. doi: 10.1007/s10549-014-2880-3. Epub 2014 Feb 22.

50.

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo.

Solan JL, Lampe PD.

FEBS Lett. 2014 Apr 17;588(8):1423-9. doi: 10.1016/j.febslet.2014.01.049. Epub 2014 Feb 4. Review.

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