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Items: 1 to 50 of 235

1.

Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC.

Yoshikawa H, Larance M, Harney DJ, Sundaramoorthy R, Ly T, Owen-Hughes T, Lamond AI.

Elife. 2018 Aug 10;7. pii: e36530. doi: 10.7554/eLife.36530.

2.

PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ.

Jonik-Nowak B, Menneteau T, Fesquet D, Baldin V, Bonne-Andrea C, Méchali F, Fabre B, Boisguerin P, de Rossi S, Henriquet C, Pugnière M, Ducoux-Petit M, Burlet-Schiltz O, Lamond AI, Fort P, Boulon S, Bousquet MP, Coux O.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6477-E6486. doi: 10.1073/pnas.1722299115. Epub 2018 Jun 22.

3.

Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells.

Ly T, Endo A, Brenes A, Gierlinski M, Afzal V, Pawellek A, Lamond AI.

Wellcome Open Res. 2018 May 2;3:51. doi: 10.12688/wellcomeopenres.14392.1. eCollection 2018.

4.

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.

Loftus RM, Assmann N, Kedia-Mehta N, O'Brien KL, Garcia A, Gillespie C, Hukelmann JL, Oefner PJ, Lamond AI, Gardiner CM, Dettmer K, Cantrell DA, Sinclair LV, Finlay DK.

Nat Commun. 2018 Jun 14;9(1):2341. doi: 10.1038/s41467-018-04719-2.

5.

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.

Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM.

Nature. 2018 Apr;556(7701):376-380. doi: 10.1038/s41586-018-0032-3. Epub 2018 Apr 11.

PMID:
29643507
6.

Proteomic Analysis of the Cell Cycle of Procylic Form Trypanosoma brucei.

Crozier TWM, Tinti M, Wheeler RJ, Ly T, Ferguson MAJ, Lamond AI.

Mol Cell Proteomics. 2018 Jun;17(6):1184-1195. doi: 10.1074/mcp.RA118.000650. Epub 2018 Mar 19.

7.

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCFSlmb degron.

Gray KM, Kaifer KA, Baillat D, Wen Y, Bonacci TR, Ebert AD, Raimer AC, Spring AM, Have ST, Glascock JJ, Gupta K, Van Duyne GD, Emanuele MJ, Lamond AI, Wagner EJ, Lorson CL, Matera AG.

Mol Biol Cell. 2018 Jan 15;29(2):96-110. doi: 10.1091/mbc.E17-11-0627. Epub 2017 Nov 22.

8.

Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS.

Ly T, Whigham A, Clarke R, Brenes-Murillo AJ, Estes B, Madhessian D, Lundberg E, Wadsworth P, Lamond AI.

Elife. 2017 Oct 20;6. pii: e27574. doi: 10.7554/eLife.27574.

9.

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis.

Mishra A, Oulès B, Pisco AO, Ly T, Liakath-Ali K, Walko G, Viswanathan P, Tihy M, Nijjher J, Dunn SJ, Lamond AI, Watt FM.

Elife. 2017 Oct 18;6. pii: e27356. doi: 10.7554/eLife.27356.

10.

Prediction of Protein Complexes in Trypanosoma brucei by Protein Correlation Profiling Mass Spectrometry and Machine Learning.

Crozier TWM, Tinti M, Larance M, Lamond AI, Ferguson MAJ.

Mol Cell Proteomics. 2017 Dec;16(12):2254-2267. doi: 10.1074/mcp.O117.068122. Epub 2017 Oct 17.

11.

The Encyclopedia of Proteome Dynamics: a big data ecosystem for (prote)omics.

Brenes A, Afzal V, Kent R, Lamond AI.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1202-D1209. doi: 10.1093/nar/gkx807.

12.

Characterisation of the biflavonoid hinokiflavone as a pre-mRNA splicing modulator that inhibits SENP.

Pawellek A, Ryder U, Tammsalu T, King LJ, Kreinin H, Ly T, Hay RT, Hartley RC, Lamond AI.

Elife. 2017 Sep 8;6. pii: e27402. doi: 10.7554/eLife.27402.

13.

The Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.

Akay A, Di Domenico T, Suen KM, Nabih A, Parada GE, Larance M, Medhi R, Berkyurek AC, Zhang X, Wedeles CJ, Rudolph KLM, Engelhardt J, Hemberg M, Ma P, Lamond AI, Claycomb JM, Miska EA.

Dev Cell. 2017 Aug 7;42(3):241-255.e6. doi: 10.1016/j.devcel.2017.07.002.

14.

Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans.

Harvald EB, Sprenger RR, Dall KB, Ejsing CS, Nielsen R, Mandrup S, Murillo AB, Larance M, Gartner A, Lamond AI, Færgeman NJ.

Cell Syst. 2017 Jul 26;5(1):38-52.e4. doi: 10.1016/j.cels.2017.06.004. Epub 2017 Jul 19.

15.

New Apex in Proteome Analysis.

Ly T, Lamond AI.

Cell Syst. 2017 Jun 28;4(6):581-582. doi: 10.1016/j.cels.2017.06.009.

16.

Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development.

Offenburger SL, Bensaddek D, Murillo AB, Lamond AI, Gartner A.

Sci Rep. 2017 Jun 28;7(1):4314. doi: 10.1038/s41598-017-04375-4.

17.

Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ.

Nature. 2017 Jun 29;546(7660):686. doi: 10.1038/nature23012. Epub 2017 Jun 14.

PMID:
28614302
18.

Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ.

Nature. 2017 Jun 15;546(7658):370-375. doi: 10.1038/nature22403. Epub 2017 May 10. Erratum in: Nature. 2017 Jun 29;546(7660):686.

19.

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation.

Hiraga SI, Ly T, Garzón J, Hořejší Z, Ohkubo YN, Endo A, Obuse C, Boulton SJ, Lamond AI, Donaldson AD.

EMBO Rep. 2017 Mar;18(3):403-419. doi: 10.15252/embr.201641983. Epub 2017 Jan 11.

20.

The Chromatin Assembly Factor Complex 1 (CAF1) and 5-Azacytidine (5-AzaC) Affect Cell Motility in Src-transformed Human Epithelial Cells.

Endo A, Ly T, Pippa R, Bensaddek D, Nicolas A, Lamond AI.

J Biol Chem. 2017 Jan 6;292(1):172-184. doi: 10.1074/jbc.M116.751024. Epub 2016 Nov 21.

21.

Unlocking the chromatin code by deciphering protein-DNA interactions.

Bensaddek D, Lamond AI.

Mol Syst Biol. 2016 Nov 10;12(11):887. doi: 10.15252/msb.20167332. No abstract available.

22.

Analysis of Mass Spectrometry Data for Nucleolar Proteomics Experiments.

Nicolas A, Bensaddek D, Lamond AI.

Methods Mol Biol. 2016;1455:263-76. doi: 10.1007/978-1-4939-3792-9_21.

PMID:
27576726
23.

Quantitative Proteomic Analysis of the Human Nucleolus.

Bensaddek D, Nicolas A, Lamond AI.

Methods Mol Biol. 2016;1455:249-62. doi: 10.1007/978-1-4939-3792-9_20.

PMID:
27576725
24.

Deep Proteome Analysis Identifies Age-Related Processes in C. elegans.

Narayan V, Ly T, Pourkarimi E, Murillo AB, Gartner A, Lamond AI, Kenyon C.

Cell Syst. 2016 Aug;3(2):144-159. doi: 10.1016/j.cels.2016.06.011. Epub 2016 Jul 21.

25.

Enhanced snoMEN Vectors Facilitate Establishment of GFP-HIF-1α Protein Replacement Human Cell Lines.

Ono M, Yamada K, Bensaddek D, Afzal V, Biddlestone J, Ortmann B, Mudie S, Boivin V, Scott MS, Rocha S, Lamond AI.

PLoS One. 2016 Apr 29;11(4):e0154759. doi: 10.1371/journal.pone.0154759. eCollection 2016.

26.

Global Membrane Protein Interactome Analysis using In vivo Crosslinking and Mass Spectrometry-based Protein Correlation Profiling.

Larance M, Kirkwood KJ, Tinti M, Brenes Murillo A, Ferguson MA, Lamond AI.

Mol Cell Proteomics. 2016 Jul;15(7):2476-90. doi: 10.1074/mcp.O115.055467. Epub 2016 Apr 25.

27.

Evaluating the use of HILIC in large-scale, multi dimensional proteomics: Horses for courses?

Bensaddek D, Nicolas A, Lamond AI.

Int J Mass Spectrom. 2015 Nov 30;391:105-114.

28.

CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells.

Ortmann B, Bensaddek D, Carvalhal S, Moser SC, Mudie S, Griffis ER, Swedlow JR, Lamond AI, Rocha S.

J Cell Sci. 2016 Jan 1;129(1):191-205. doi: 10.1242/jcs.179911. Epub 2015 Dec 7.

29.

Micro-proteomics with iterative data analysis: Proteome analysis in C. elegans at the single worm level.

Bensaddek D, Narayan V, Nicolas A, Murillo AB, Gartner A, Kenyon CJ, Lamond AI.

Proteomics. 2016 Feb;16(3):381-92. doi: 10.1002/pmic.201500264. Epub 2016 Jan 7.

30.

The cytotoxic T cell proteome and its shaping by the kinase mTOR.

Hukelmann JL, Anderson KE, Sinclair LV, Grzes KM, Murillo AB, Hawkins PT, Stephens LR, Lamond AI, Cantrell DA.

Nat Immunol. 2016 Jan;17(1):104-12. doi: 10.1038/ni.3314. Epub 2015 Nov 9.

31.

Targeted Knock-Down of miR21 Primary Transcripts Using snoMEN Vectors Induces Apoptosis in Human Cancer Cell Lines.

Ono M, Yamada K, Avolio F, Afzal V, Bensaddek D, Lamond AI.

PLoS One. 2015 Sep 25;10(9):e0138668. doi: 10.1371/journal.pone.0138668. eCollection 2015.

32.

Global Proteomics Analysis of the Response to Starvation in C. elegans.

Larance M, Pourkarimi E, Wang B, Brenes Murillo A, Kent R, Lamond AI, Gartner A.

Mol Cell Proteomics. 2015 Jul;14(7):1989-2001. doi: 10.1074/mcp.M114.044289. Epub 2015 May 11.

33.

The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway.

Bailly A, Perrin A, Bou Malhab LJ, Pion E, Larance M, Nagala M, Smith P, O'Donohue MF, Gleizes PE, Zomerdijk J, Lamond AI, Xirodimas DP.

Oncogene. 2016 Jan 28;35(4):415-26. doi: 10.1038/onc.2015.104. Epub 2015 Apr 13.

PMID:
25867069
34.

Multidimensional proteomics for cell biology.

Larance M, Lamond AI.

Nat Rev Mol Cell Biol. 2015 May;16(5):269-80. doi: 10.1038/nrm3970. Epub 2015 Apr 10. Review.

PMID:
25857810
35.

Identification of small molecule inhibitors of pre-mRNA splicing.

Pawallek A, McElroy S, Samatov T, Mitchell L, Woodland A, Ryder U, Gray D, Lührmann R, Lamond AI.

J Biol Chem. 2015 Mar 6;290(10):6005. doi: 10.1074/jbc.A114.590976. No abstract available.

36.

Time-lapse imaging of nuclear bodies.

Hutten S, Swift S, Lamond AI.

Methods Mol Biol. 2015;1262:55-67. doi: 10.1007/978-1-4939-2253-6_4.

PMID:
25555575
37.

Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells.

Ly T, Endo A, Lamond AI.

Elife. 2015 Jan 2;4. doi: 10.7554/eLife.04534.

38.

Identification of small molecule inhibitors of pre-mRNA splicing.

Pawellek A, McElroy S, Samatov T, Mitchell L, Woodland A, Ryder U, Gray D, Lührmann R, Lamond AI.

J Biol Chem. 2014 Dec 12;289(50):34683-98. doi: 10.1074/jbc.M114.590976. Epub 2014 Oct 3. Erratum in: J Biol Chem. 2015 Mar 6;290(10):6005.

39.

FMDV replicons encoding green fluorescent protein are replication competent.

Tulloch F, Pathania U, Luke GA, Nicholson J, Stonehouse NJ, Rowlands DJ, Jackson T, Tuthill T, Haas J, Lamond AI, Ryan MD.

J Virol Methods. 2014 Dec;209:35-40. doi: 10.1016/j.jviromet.2014.08.020. Epub 2014 Sep 4.

40.

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells.

Ly T, Ahmad Y, Shlien A, Soroka D, Mills A, Emanuele MJ, Stratton MR, Lamond AI.

Elife. 2014 Jan 1;3:e01630. doi: 10.7554/eLife.01630.

41.

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.

Hutten S, Chachami G, Winter U, Melchior F, Lamond AI.

J Cell Sci. 2014 Mar 1;127(Pt 5):1065-78. doi: 10.1242/jcs.141788. Epub 2014 Jan 10.

42.

A perspective on proteomics in cell biology.

Ahmad Y, Lamond AI.

Trends Cell Biol. 2014 Apr;24(4):257-64. doi: 10.1016/j.tcb.2013.10.010. Epub 2013 Nov 24. Review.

43.

Characterization of native protein complexes and protein isoform variation using size-fractionation-based quantitative proteomics.

Kirkwood KJ, Ahmad Y, Larance M, Lamond AI.

Mol Cell Proteomics. 2013 Dec;12(12):3851-73. doi: 10.1074/mcp.M113.032367. Epub 2013 Sep 16.

44.

Plant SILAC: stable-isotope labelling with amino acids of arabidopsis seedlings for quantitative proteomics.

Lewandowska D, ten Have S, Hodge K, Tillemans V, Lamond AI, Brown JW.

PLoS One. 2013 Aug 20;8(8):e72207. doi: 10.1371/journal.pone.0072207. eCollection 2013.

45.

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192.

Moser SC, Bensaddek D, Ortmann B, Maure JF, Mudie S, Blow JJ, Lamond AI, Swedlow JR, Rocha S.

Dev Cell. 2013 Aug 26;26(4):381-92. doi: 10.1016/j.devcel.2013.06.014. Epub 2013 Aug 8.

46.

Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations.

Visvanathan A, Ahmed K, Even-Faitelson L, Lleres D, Bazett-Jones DP, Lamond AI.

PLoS One. 2013 Jun 26;8(6):e67689. doi: 10.1371/journal.pone.0067689. Print 2013.

47.

FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21.

Yamada K, Ono M, Bensaddek D, Lamond AI, Rocha S.

Cell Cycle. 2013 Aug 1;12(15):2348-54. doi: 10.4161/cc.25511. Epub 2013 Jul 1.

48.

Analysis of human protein replacement stable cell lines established using snoMEN-PR vector.

Ono M, Yamada K, Endo A, Avolio F, Lamond AI.

PLoS One. 2013 Apr 25;8(4):e62305. doi: 10.1371/journal.pone.0062305. Print 2013.

49.

Cleaning up the masses: exclusion lists to reduce contamination with HPLC-MS/MS.

Hodge K, Have ST, Hutton L, Lamond AI.

J Proteomics. 2013 Aug 2;88:92-103. doi: 10.1016/j.jprot.2013.02.023. Epub 2013 Mar 15.

50.

Identification and functional characterization of FMN2, a regulator of the cyclin-dependent kinase inhibitor p21.

Yamada K, Ono M, Perkins ND, Rocha S, Lamond AI.

Mol Cell. 2013 Mar 7;49(5):922-33. doi: 10.1016/j.molcel.2012.12.023. Epub 2013 Jan 31.

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