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Items: 23


Isolation and Differentiation of Primary Myoblasts from Mouse Skeletal Muscle Explants.

Vaughan M, Lamia KA.

J Vis Exp. 2019 Oct 15;(152). doi: 10.3791/60310.


Phosphorylation of CRY1 Serine 71 Alters Voluntary Activity but Not Circadian Rhythms In Vivo.

Vaughan M, Jordan SD, Duglan D, Chan AB, Afetian M, Lamia KA.

J Biol Rhythms. 2019 Aug;34(4):401-409. doi: 10.1177/0748730419858525. Epub 2019 Jul 1.


Clocking In, Working Out: Circadian Regulation of Exercise Physiology.

Duglan D, Lamia KA.

Trends Endocrinol Metab. 2019 Jun;30(6):347-356. doi: 10.1016/j.tem.2019.04.003. Epub 2019 May 2. Review.


The circadian E3 ligase complex SCFFBXL3+CRY targets TLK2.

Correia SP, Chan AB, Vaughan M, Zolboot N, Perea V, Huber AL, Kriebs A, Moresco JJ, Yates JR 3rd, Lamia KA.

Sci Rep. 2019 Jan 17;9(1):198. doi: 10.1038/s41598-018-36618-3.


Ticking time bombs: connections between circadian clocks and cancer.

Lamia KA.

F1000Res. 2017 Oct 30;6:1910. doi: 10.12688/f1000research.11770.1. eCollection 2017. Review.


The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin.

Henriksson E, Huber AL, Soto EK, Kriebs A, Vaughan ME, Duglan D, Chan AB, Papp SJ, Nguyen M, Afetian ME, Lamia KA.

J Biol Rhythms. 2017 Aug;32(4):345-358. doi: 10.1177/0748730417710348. Epub 2017 Jun 15.


Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity.

Kriebs A, Jordan SD, Soto E, Henriksson E, Sandate CR, Vaughan ME, Chan AB, Duglan D, Papp SJ, Huber AL, Afetian ME, Yu RT, Zhao X, Downes M, Evans RM, Lamia KA.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):8776-8781. doi: 10.1073/pnas.1704955114. Epub 2017 Jul 27.


CRY1/2 Selectively Repress PPARĪ“ and Limit Exercise Capacity.

Jordan SD, Kriebs A, Vaughan M, Duglan D, Fan W, Henriksson E, Huber AL, Papp SJ, Nguyen M, Afetian M, Downes M, Yu RT, Kralli A, Evans RM, Lamia KA.

Cell Metab. 2017 Jul 5;26(1):243-255.e6. doi: 10.1016/j.cmet.2017.06.002.


CRY2 and FBXL3 Cooperatively Degrade c-MYC.

Huber AL, Papp SJ, Chan AB, Henriksson E, Jordan SD, Kriebs A, Nguyen M, Wallace M, Li Z, Metallo CM, Lamia KA.

Mol Cell. 2016 Nov 17;64(4):774-789. doi: 10.1016/j.molcel.2016.10.012. Epub 2016 Nov 10.


Adipose Clocks: Burning the Midnight Oil.

Henriksson E, Lamia KA.

J Biol Rhythms. 2015 Oct;30(5):364-73. doi: 10.1177/0748730415581234. Epub 2015 Apr 29. Review.


DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.

Papp SJ, Huber AL, Jordan SD, Kriebs A, Nguyen M, Moresco JJ, Yates JR, Lamia KA.

Elife. 2015 Mar 10;4. doi: 10.7554/eLife.04883.


Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.

Emerling BM, Hurov JB, Poulogiannis G, Tsukazawa KS, Choo-Wing R, Wulf GM, Bell EL, Shim HS, Lamia KA, Rameh LE, Bellinger G, Sasaki AT, Asara JM, Yuan X, Bullock A, Denicola GM, Song J, Brown V, Signoretti S, Cantley LC.

Cell. 2013 Nov 7;155(4):844-57. doi: 10.1016/j.cell.2013.09.057.


AMPK at the crossroads of circadian clocks and metabolism.

Jordan SD, Lamia KA.

Mol Cell Endocrinol. 2013 Feb 25;366(2):163-9. doi: 10.1016/j.mce.2012.06.017. Epub 2012 Jun 28. Review.


Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.

Lamia KA, Papp SJ, Yu RT, Barish GD, Uhlenhaut NH, Jonker JW, Downes M, Evans RM.

Nature. 2011 Dec 14;480(7378):552-6. doi: 10.1038/nature10700.


An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice.

Sadacca LA, Lamia KA, deLemos AS, Blum B, Weitz CJ.

Diabetologia. 2011 Jan;54(1):120-4. doi: 10.1007/s00125-010-1920-8. Epub 2010 Oct 3.


Metabolism: Tick, tock, a beta-cell clock.

Lamia KA, Evans RM.

Nature. 2010 Jul 29;466(7306):571-2. doi: 10.1038/466571a. No abstract available.


AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation.

Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB, Evans RM.

Science. 2009 Oct 16;326(5951):437-40. doi: 10.1126/science.1172156.


Physiological significance of a peripheral tissue circadian clock.

Lamia KA, Storch KF, Weitz CJ.

Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15172-7. doi: 10.1073/pnas.0806717105. Epub 2008 Sep 8.


Nuclear receptors, metabolism, and the circadian clock.

Yang X, Lamia KA, Evans RM.

Cold Spring Harb Symp Quant Biol. 2007;72:387-94. doi: 10.1101/sqb.2007.72.058. Review.


The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin.

Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC.

Science. 2005 Dec 9;310(5754):1642-6. Epub 2005 Nov 24.


Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice.

Lamia KA, Peroni OD, Kim YB, Rameh LE, Kahn BB, Cantley LC.

Mol Cell Biol. 2004 Jun;24(11):5080-7.


The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.

Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, Rameh LE.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9867-72. Epub 2003 Aug 1.


Lipid research picks up speed on the slopes of Taos.

Field SJ, Lamia KA, Rameh LE, Cantley LC.

Dev Cell. 2002 Apr;2(4):407-10.

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