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Items: 35


AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region.

van den Berg FT, Makoah NA, Ali SA, Scott TA, Mapengo RE, Mutsvunguma LZ, Mkhize NN, Lambson BE, Kgagudi PD, Crowther C, Abdool Karim SS, Balazs AB, Weinberg MS, Ely A, Arbuthnot PB, Morris L.

Mol Ther Methods Clin Dev. 2019 Jun 12;14:100-112. doi: 10.1016/j.omtm.2019.06.002. eCollection 2019 Sep 13.


Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan.

Umotoy J, Bagaya BS, Joyce C, Schiffner T, Menis S, Saye-Francisco KL, Biddle T, Mohan S, Vollbrecht T, Kalyuzhniy O, Madzorera S, Kitchin D, Lambson B, Nonyane M, Kilembe W; IAVI Protocol C Investigators; IAVI African HIV Research Network, Poignard P, Schief WR, Burton DR, Murrell B, Moore PL, Briney B, Sok D, Landais E.

Immunity. 2019 Jul 16;51(1):141-154.e6. doi: 10.1016/j.immuni.2019.06.004.


Evidence for both Intermittent and Persistent Compartmentalization of HIV-1 in the Female Genital Tract.

Mabvakure BM, Lambson BE, Ramdayal K, Masson L, Kitchin D, Allam M, Abdool Karim S, Williamson C, Passmore JA, Martin DP, Scheepers C, Moore PL, Harkins GW, Morris L.

J Virol. 2019 May 1;93(10). pii: e00311-19. doi: 10.1128/JVI.00311-19. Print 2019 May 15.


V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.

van Eeden C, Wibmer CK, Scheepers C, Richardson SI, Nonyane M, Lambson B, Mkhize NN, Vijayakumar B, Sheng Z, Stanfield-Oakley S, Bhiman JN, Bekker V, Hermanus T, Mabvakure B, Ismail A, Moody MA, Wiehe K, Garrett N, Karim SA, Dirr H, Fernandes MA, Sayed Y, Shapiro L, Ferrari G, Haynes BF, Moore PL, Morris L.

Cell Rep. 2018 Dec 11;25(11):3123-3135.e6. doi: 10.1016/j.celrep.2018.11.058.


A38 Diversity analyses of HIV-1 envelope glycoproteins in HIV-infected individuals with and without broadly neutralizing antibodies.

Mabvakure B, Scheepers C, Nonyane M, Lambson B, Madzorera S, Kitchin D, Bhiman J, Wibmer K, Abdool Karim S, Williamson C, Morris L, Moore PL.

Virus Evol. 2017 Mar 5;3(Suppl 1). pii: vew036.037. doi: 10.1093/ve/vew036.037. eCollection 2017 Mar. No abstract available.


Experimental test of Landauer's principle in single-bit operations on nanomagnetic memory bits.

Hong J, Lambson B, Dhuey S, Bokor J.

Sci Adv. 2016 Mar 11;2(3):e1501492. doi: 10.1126/sciadv.1501492. eCollection 2016 Mar.


South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication.

Richardson SI, Gray ES, Mkhize NN, Sheward DJ, Lambson BE, Wibmer CK, Masson L, Werner L, Garrett N, Passmore JA, Karim QA, Karim SS, Williamson C, Moore PL, Morris L.

Retrovirology. 2015 Jun 24;12:54. doi: 10.1186/s12977-015-0183-3.


Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire.

Scheepers C, Shrestha RK, Lambson BE, Jackson KJ, Wright IA, Naicker D, Goosen M, Berrie L, Ismail A, Garrett N, Abdool Karim Q, Abdool Karim SS, Moore PL, Travers SA, Morris L.

J Immunol. 2015 May 1;194(9):4371-8. doi: 10.4049/jimmunol.1500118. Epub 2015 Mar 30.


Sub-nanosecond signal propagation in anisotropy-engineered nanomagnetic logic chains.

Gu Z, Nowakowski ME, Carlton DB, Storz R, Im MY, Hong J, Chao W, Lambson B, Bennett P, Alam MT, Marcus MA, Doran A, Young A, Scholl A, Fischer P, Bokor J.

Nat Commun. 2015 Mar 16;6:6466. doi: 10.1038/ncomms7466.


Evaluation of a gp63-PCR based assay as a molecular diagnosis tool in canine leishmaniasis in Tunisia.

Guerbouj S, Djilani F, Bettaieb J, Lambson B, Diouani MF, Ben Salah A, Ben Ismail R, Guizani I.

PLoS One. 2014 Aug 25;9(8):e105419. doi: 10.1371/journal.pone.0105419. eCollection 2014.


HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria.

Trama AM, Moody MA, Alam SM, Jaeger FH, Lockwood B, Parks R, Lloyd KE, Stolarchuk C, Scearce R, Foulger A, Marshall DJ, Whitesides JF, Jeffries TL Jr, Wiehe K, Morris L, Lambson B, Soderberg K, Hwang KK, Tomaras GD, Vandergrift N, Jackson KJL, Roskin KM, Boyd SD, Kepler TB, Liao HX, Haynes BF.

Cell Host Microbe. 2014 Aug 13;16(2):215-226. doi: 10.1016/j.chom.2014.07.003.


Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape.

Moore PL, Gray ES, Wibmer CK, Bhiman JN, Nonyane M, Sheward DJ, Hermanus T, Bajimaya S, Tumba NL, Abrahams MR, Lambson BE, Ranchobe N, Ping L, Ngandu N, Abdool Karim Q, Abdool Karim SS, Swanstrom RI, Seaman MS, Williamson C, Morris L.

Nat Med. 2012 Nov;18(11):1688-92. doi: 10.1038/nm.2985. Epub 2012 Oct 21.


Exploring the thermodynamic limits of computation in integrated systems: magnetic memory, nanomagnetic logic, and the Landauer limit.

Lambson B, Carlton D, Bokor J.

Phys Rev Lett. 2011 Jul 1;107(1):010604. Epub 2011 Jul 1.


Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual.

Gray ES, Moody MA, Wibmer CK, Chen X, Marshall D, Amos J, Moore PL, Foulger A, Yu JS, Lambson B, Abdool Karim S, Whitesides J, Tomaras GD, Haynes BF, Morris L, Liao HX.

J Virol. 2011 Aug;85(15):7719-29. doi: 10.1128/JVI.00563-11. Epub 2011 May 25.


Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin.

Alexandre KB, Gray ES, Lambson BE, Moore PL, Choge IA, Mlisana K, Karim SS, McMahon J, O'Keefe B, Chikwamba R, Morris L.

Virology. 2010 Jun 20;402(1):187-96. doi: 10.1016/j.virol.2010.03.021. Epub 2010 Apr 13.


Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.

Moore PL, Ranchobe N, Lambson BE, Gray ES, Cave E, Abrahams MR, Bandawe G, Mlisana K, Abdool Karim SS, Williamson C, Morris L; CAPRISA 002 Study; NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI).

PLoS Pathog. 2009 Sep;5(9):e1000598. doi: 10.1371/journal.ppat.1000598. Epub 2009 Sep 18.


Identification of candidate sialome components expressed in ixodid tick salivary glands using secretion signal complementation in mammalian cells.

Lambson B, Nene V, Obura M, Shah T, Pandit P, Ole-Moiyoi O, Delroux K, Welburn S, Skilton R, de Villiers E, Bishop R.

Insect Mol Biol. 2005 Aug;14(4):403-14.


A cement protein of the tick Rhipicephalus appendiculatus, located in the secretory e cell granules of the type III salivary gland acini, induces strong antibody responses in cattle.

Bishop R, Lambson B, Wells C, Pandit P, Osaso J, Nkonge C, Morzaria S, Musoke A, Nene V.

Int J Parasitol. 2002 Jun 15;32(7):833-42.


Homologous minicircles in Leishmania donovani.

Lambson B, Barker DC.

Trans R Soc Trop Med Hyg. 2002 Apr;96 Suppl 1:S75-80.


Diagnosis of leishmaniasis in Maltese dogs with the aid of the polymerase chain reaction.

Headington CE, Barbara CH, Lambson BE, Hart DT, Barker DC.

Trans R Soc Trop Med Hyg. 2002 Apr;96 Suppl 1:S195-7.


Leishmania (Viannia) spp. dissemination and tissue tropism in naturally infected dogs (Canis familiaris).

Reithinger R, Lambson BE, Barker DC, Counihan H, Espinoza CJ, González JS, Davies CR.

Trans R Soc Trop Med Hyg. 2002 Jan-Feb;96(1):76-8.


Detection of Leishmania infantum by PCR, serology and cellular immune response in a cohort study of Brazilian dogs.

Quinnell RJ, Courtenay O, Davidson S, Garcez L, Lambson B, Ramos P, Shaw JJ, Shaw MA, Dye C.

Parasitology. 2001 Mar;122(Pt 3):253-61.


Corrigendum to "Intra and inter-specific microsatellite variation in the leishmania subgenus Viannia".

Russell R, Pilar Iribar M, Lambson B, Brewster S, Blackwell JM, Dye C, Ajioka JW.

Mol Biochem Parasitol. 2000 Apr 15;107(2):331. No abstract available.


Kala-azar in a high transmission focus: an ethnic and geographic dimension.

Ibrahim ME, Lambson B, Yousif AO, Deifalla NS, Alnaiem DA, Ismail A, Yousif H, Ghalib HW, Khalil EA, Kadaro A, Barker DC, El Hassan AM.

Am J Trop Med Hyg. 1999 Dec;61(6):941-4.


Use of PCR to detect Leishmania (Viannia) spp. in dog blood and bone marrow.

Reithinger R, Lambson BE, Barker DC, Davies CR.

J Clin Microbiol. 2000 Feb;38(2):748-51. Erratum in: J Clin Microbiol 2000 Aug;38(8):3141.


Intra and inter-specific microsatellite variation in the Leishmania subgenus Viannia.

Russell R, Iribar MP, Lambson B, Brewster S, Blackwell JM, Dye C, Ajioka JW.

Mol Biochem Parasitol. 1999 Sep 20;103(1):71-7. Erratum in: Mol Biochem Parasitol 2000 Apr 15;107(2):331.


Leishmania tropica is a probable cause of cutaneous leishmaniasis in the Sultanate of Oman: case report in a Pakistani resident.

Scrimgeour EM, Windsor JJ, Shetty MK, Banodkar DD, Lambson B, Barker DC, Idris MA, McCann SH, al-Suwaid AR.

Trans R Soc Trop Med Hyg. 1999 May-Jun;93(3):233-4. No abstract available.


Sequence homology within a minicircle class of the Leishmania donovani complex.

Lambson B, Smyth A, Barker D.

Mol Biochem Parasitol. 1999 Jun 25;101(1-2):229-32. No abstract available.


Characterisation of kinetoplast DNA minicircles from Herpetomonas samuelpessoai.

Fu G, Lambson B, Barker D.

FEMS Microbiol Lett. 1999 Mar 1;172(1):65-71.


First identification of a species of Leishmania causing visceral leishmaniasis in the Sultanate of Oman, in a patient with AIDS.

Scrimgeour EM, Barker DC, al-Waily A, Idris M, Lambson B, Nirmala V, Windsor JJ.

Trans R Soc Trop Med Hyg. 1998 May-Jun;92(3):356-7. No abstract available.


The sequence organization of Yp/proximal Xq homologous regions of the human sex chromosomes is highly conserved.

Sargent CA, Briggs H, Chalmers IJ, Lambson B, Walker E, Affara NA.

Genomics. 1996 Mar 1;32(2):200-9.


A set of ninety-seven overlapping yeast artificial chromosome clones spanning the human Y chromosome euchromatin.

Jones MH, Khwaja OS, Briggs H, Lambson B, Davey PM, Chalmers J, Zhou CY, Walker EM, Zhang Y, Todd C, et al.

Genomics. 1994 Nov 15;24(2):266-75.


Evolution of DNA sequence homologies between the sex chromosomes in primate species.

Lambson B, Affara NA, Mitchell M, Ferguson-Smith MA.

Genomics. 1992 Dec;14(4):1032-40.


Chromosomal evolution in secretory and nonsecretory subline of MOPC 21.

Lambson BE, Bernstein R, Mendelow BV.

Somat Cell Mol Genet. 1990 Jan;16(1):91-5.


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