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Items: 1 to 50 of 96

1.

Expression of the murine norovirus (MNV) ORF1 polyprotein is sufficient to induce apoptosis in a virus-free cell model.

Herod MR, Salim O, Skilton RJ, Prince CA, Ward VK, Lambden PR, Clarke IN.

PLoS One. 2014 Mar 5;9(3):e90679. doi: 10.1371/journal.pone.0090679. eCollection 2014.

2.

Genetic transformation of a clinical (genital tract), plasmid-free isolate of Chlamydia trachomatis: engineering the plasmid as a cloning vector.

Wang Y, Kahane S, Cutcliffe LT, Skilton RJ, Lambden PR, Persson K, Bjartling C, Clarke IN.

PLoS One. 2013;8(3):e59195. doi: 10.1371/journal.pone.0059195. Epub 2013 Mar 18.

3.

Inherent structural disorder and dimerisation of murine norovirus NS1-2 protein.

Baker ES, Luckner SR, Krause KL, Lambden PR, Clarke IN, Ward VK.

PLoS One. 2012;7(2):e30534. doi: 10.1371/journal.pone.0030534. Epub 2012 Feb 7.

4.

Development of a transformation system for Chlamydia trachomatis: restoration of glycogen biosynthesis by acquisition of a plasmid shuttle vector.

Wang Y, Kahane S, Cutcliffe LT, Skilton RJ, Lambden PR, Clarke IN.

PLoS Pathog. 2011 Sep;7(9):e1002258. doi: 10.1371/journal.ppat.1002258. Epub 2011 Sep 22.

5.

Infection of calves with bovine norovirus GIII.1 strain Jena virus: an experimental model to study the pathogenesis of norovirus infection.

Otto PH, Clarke IN, Lambden PR, Salim O, Reetz J, Liebler-Tenorio EM.

J Virol. 2011 Nov;85(22):12013-21. doi: 10.1128/JVI.05342-11. Epub 2011 Aug 31.

6.

A structural study of norovirus 3C protease specificity: binding of a designed active site-directed peptide inhibitor.

Hussey RJ, Coates L, Gill RS, Erskine PT, Coker SF, Mitchell E, Cooper JB, Wood S, Broadbridge R, Clarke IN, Lambden PR, Shoolingin-Jordan PM.

Biochemistry. 2011 Jan 18;50(2):240-9. Epub 2010 Dec 15.

7.

Crystallization and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael acceptor inhibitor.

Hussey RJ, Coates L, Gill RS, Wright JN, Sarwar M, Coker S, Erskine PT, Cooper JB, Wood S, Clarke IN, Lambden PR, Broadbridge R, Shoolingin-Jordan PM.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Nov 1;66(Pt 11):1544-8. doi: 10.1107/S1744309110039059. Epub 2010 Oct 29.

8.

Penicillin induced persistence in Chlamydia trachomatis: high quality time lapse video analysis of the developmental cycle.

Skilton RJ, Cutcliffen LT, Barlow D, Wang Y, Salim O, Lambden PR, Clarke IN.

PLoS One. 2009 Nov 6;4(11):e7723. doi: 10.1371/journal.pone.0007723.

9.

Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain.

Seth-Smith HM, Harris SR, Persson K, Marsh P, Barron A, Bignell A, Bjartling C, Clark L, Cutcliffe LT, Lambden PR, Lennard N, Lockey SJ, Quail MA, Salim O, Skilton RJ, Wang Y, Holland MJ, Parkhill J, Thomson NR, Clarke IN.

BMC Genomics. 2009 May 21;10:239. doi: 10.1186/1471-2164-10-239.

10.
11.

Behind the chlamydial cloak: the replication cycle of chlamydiaphage Chp2, revealed.

Salim O, Skilton RJ, Lambden PR, Fane BA, Clarke IN.

Virology. 2008 Aug 1;377(2):440-5. doi: 10.1016/j.virol.2008.05.001.

12.

Functional analysis of the 5' genomic sequence of a bovine norovirus.

Salim O, Clarke IN, Lambden PR.

PLoS One. 2008 May 14;3(5):e2169. doi: 10.1371/journal.pone.0002169.

13.

Serotype 1 and 2 bovine noroviruses are endemic in cattle in the United kingdom and Germany.

Oliver SL, Wood E, Asobayire E, Wathes DC, Brickell JS, Elschner M, Otto P, Lambden PR, Clarke IN, Bridger JC.

J Clin Microbiol. 2007 Sep;45(9):3050-2. Epub 2007 Jun 27.

14.

Recovery of infectious murine norovirus using pol II-driven expression of full-length cDNA.

Ward VK, McCormick CJ, Clarke IN, Salim O, Wobus CE, Thackray LB, Virgin HW 4th, Lambden PR.

Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11050-5. Epub 2007 Jun 20.

15.

Intracellular parasitism of chlamydiae: specific infectivity of chlamydiaphage Chp2 in Chlamydophila abortus.

Skilton RJ, Cutcliffe LT, Pickett MA, Lambden PR, Fane BA, Clarke IN.

J Bacteriol. 2007 Jul;189(13):4957-9. Epub 2007 Apr 27.

16.

The effect of penicillin on Chlamydia trachomatis DNA replication.

Lambden PR, Pickett MA, Clarke IN.

Microbiology. 2006 Sep;152(Pt 9):2573-8.

PMID:
16946252
17.

Characterization of a cross-reactive linear epitope in human genogroup I and bovine genogroup III norovirus capsid proteins.

Batten CA, Clarke IN, Kempster SL, Oliver SL, Bridger JC, Lambden PR.

Virology. 2006 Dec 5-20;356(1-2):179-87. Epub 2006 Aug 24.

18.

Genotype 1 and genotype 2 bovine noroviruses are antigenically distinct but share a cross-reactive epitope with human noroviruses.

Oliver SL, Batten CA, Deng Y, Elschner M, Otto P, Charpilienne A, Clarke IN, Bridger JC, Lambden PR.

J Clin Microbiol. 2006 Mar;44(3):992-8.

19.

Chlamydiaphage Chp2, a skeleton in the phiX174 closet: scaffolding protein and procapsid identification.

Clarke IN, Cutcliffe LT, Everson JS, Garner SA, Lambden PR, Pead PJ, Pickett MA, Brentlinger KL, Fane BA.

J Bacteriol. 2004 Nov;186(22):7571-4.

20.

National epidemic of Lordsdale Norovirus in the UK.

Vipond IB, Caul EO, Hirst D, Carmen B, Curry A, Lopman BA, Pead P, Pickett MA, Lambden PR, Clarke IN.

J Clin Virol. 2004 Jul;30(3):243-7.

PMID:
15135743
21.

Isolation, molecular characterisation and genome sequence of a bacteriophage (Chp3) from Chlamydophila pecorum.

Garner SA, Everson JS, Lambden PR, Fane BA, Clarke IN.

Virus Genes. 2004 Mar;28(2):207-14.

PMID:
14976421
22.

Surveillance of norovirus infection in a study of sporadic childhood gastroenteritis in South West England and South Wales, during one winter season (1999-2000).

Froggatt PC, Barry Vipond I, Ashley CR, Lambden PR, Clarke IN, Caul EO.

J Med Virol. 2004 Feb;72(2):307-11.

PMID:
14695675
23.

Host range of chlamydiaphages phiCPAR39 and Chp3.

Everson JS, Garner SA, Lambden PR, Fane BA, Clarke IN.

J Bacteriol. 2003 Nov;185(21):6490-2.

24.

Studies of epidemiology and seroprevalence of bovine noroviruses in Germany.

Deng Y, Batten CA, Liu BL, Lambden PR, Elschner M, Günther H, Otto P, Schnürch P, Eichhorn W, Herbst W, Clarke IN.

J Clin Microbiol. 2003 Jun;41(6):2300-5.

25.

Epidemiology of human Sapporo-like caliciviruses in the South West of England: molecular characterisation of a genetically distinct isolate.

Robinson S, Clarke IN, Vipond IB, Caul EO, Lambden PR.

J Med Virol. 2002 Jun;67(2):282-8.

PMID:
11992591
26.

Biological properties and cell tropism of Chp2, a bacteriophage of the obligate intracellular bacterium Chlamydophila abortus.

Everson JS, Garner SA, Fane B, Liu BL, Lambden PR, Clarke IN.

J Bacteriol. 2002 May;184(10):2748-54.

27.

Human group C rotavirus: completion of the genome sequence and gene coding assignments of a non-cultivatable rotavirus.

Chen Z, Lambden PR, Lau J, Caul EO, Clarke IN.

Virus Res. 2002 Feb 26;83(1-2):179-87.

PMID:
11864750
28.

The molecular biology of human caliciviruses.

Clarke IN, Lambden PR.

Novartis Found Symp. 2001;238:180-91; discussion 191-6. Review.

PMID:
11444026
29.

Organization and expression of calicivirus genes.

Clarke IN, Lambden PR.

J Infect Dis. 2000 May;181 Suppl 2:S309-16. Review.

PMID:
10804143
30.

A diagnostic EIA for detection of the prevalent SRSV strain in United Kingdom outbreaks of gastroenteritis.

Vipond IB, Pelosi E, Williams J, Ashley CR, Lambden PR, Clarke IN, Caul EO.

J Med Virol. 2000 May;61(1):132-7.

PMID:
10745245
31.

Molecular characterization of a bacteriophage (Chp2) from Chlamydia psittaci.

Liu BL, Everson JS, Fane B, Giannikopoulou P, Vretou E, Lambden PR, Clarke IN.

J Virol. 2000 Apr;74(8):3464-9.

32.

Interaction of primary human endometrial cells with Neisseria gonorrhoeae expressing green fluorescent protein.

Christodoulides M, Everson JS, Liu BL, Lambden PR, Watt PJ, Thomas EJ, Heckels JE.

Mol Microbiol. 2000 Jan;35(1):32-43.

33.

Molecular characterization of human group C rotavirus genes 6, 7 and 9.

James VL, Lambden PR, Deng Y, Caul EO, Clarke IN.

J Gen Virol. 1999 Dec;80 ( Pt 12):3181-7.

PMID:
10567650
34.

The seroepidemiology of genogroup 1 and genogroup 2 Norwalk-like viruses in Italy.

Pelosi E, Lambden PR, Caul EO, Liu B, Dingle K, Deng Y, Clarke IN.

J Med Virol. 1999 May;58(1):93-9.

PMID:
10223553
35.
36.

Molecular characterization of a bovine enteric calicivirus: relationship to the Norwalk-like viruses.

Liu BL, Lambden PR, Günther H, Otto P, Elschner M, Clarke IN.

J Virol. 1999 Jan;73(1):819-25.

38.

Parkville virus: a novel genetic variant of human calicivirus in the Sapporo virus clade, associated with an outbreak of gastroenteritis in adults.

Noel JS, Liu BL, Humphrey CD, Rodriguez EM, Lambden PR, Clarke IN, Dwyer DM, Ando T, Glass RI, Monroe SS.

J Med Virol. 1997 Jun;52(2):173-8.

PMID:
9179765
39.

Seroepidemiology of human group C rotavirus in the UK.

James VL, Lambden PR, Caul EO, Cooke SJ, Clarke IN.

J Med Virol. 1997 May;52(1):86-91.

PMID:
9131463
40.

Capsid sequence diversity in small round structured viruses from recent UK outbreaks of gastroenteritis.

Green SM, Lambden PR, Caul EO, Clarke IN.

J Med Virol. 1997 May;52(1):14-9.

PMID:
9131452
41.

The molecular biology of caliciviruses.

Clarke IN, Lambden PR.

J Gen Virol. 1997 Feb;78 ( Pt 2):291-301. Review. No abstract available.

PMID:
9018049
42.

Viral zoonoses and food of animal origin: caliciviruses and human disease.

Clarke IN, Lambden PR.

Arch Virol Suppl. 1997;13:141-52. Review.

PMID:
9413534
43.

The genomic 5' terminus of Manchester calicivirus.

Liu B, Clarke IN, Caul EO, Lambden PR.

Virus Genes. 1997;15(1):25-8.

PMID:
9354265
45.

The VP3 gene of human group C rotavirus.

Samarbaf-Zadeh AR, Lambden PR, Green SM, Deng Y, Caul EO, Clarke IN.

Virus Genes. 1996;13(2):169-73.

PMID:
8972570
46.

The CrP operon of Chlamydia psittaci and Chlamydia pneumoniae.

Watson MW, Clarke IN, Everson JS, Lambden PR.

Microbiology. 1995 Oct;141 ( Pt 10):2489-97.

PMID:
7582008
47.
48.

Capsid diversity in small round-structured viruses: molecular characterization of an antigenically distinct human enteric calicivirus.

Green SM, Lambden PR, Caul EO, Ashley CR, Clarke IN.

Virus Res. 1995 Aug;37(3):271-83.

PMID:
8533462
49.

Genome organization in the caliciviridae.

Lambden PR, Clarke IN.

Trends Microbiol. 1995 Jul;3(7):261-5. Review.

PMID:
7551638
50.

Polymerase chain reaction detection of small round-structured viruses from two related hospital outbreaks of gastroenteritis using inosine-containing primers.

Green SM, Lambden PR, Deng Y, Lowes JA, Lineham S, Bushell J, Rogers J, Caul EO, Ashley CR, Clarke IN.

J Med Virol. 1995 Feb;45(2):197-202.

PMID:
7775939

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