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Items: 40

1.

Impact of the Pediatric Emergency Care Applied Research Network (PECARN) guidelines on emergency department use of head computed tomography at a level I safety-net trauma center.

Gerber N, Sookraj K, Munnangi S, Angus LDG, Lamba V, Kumar K, Doraiswamy B.

Emerg Radiol. 2019 Feb;26(1):45-52. doi: 10.1007/s10140-018-1645-4. Epub 2018 Sep 27.

PMID:
30259227
2.

An Activator-Blocker Pair Provides a Controllable On-Off Switch for a Ketosteroid Isomerase Active Site Mutant.

Lamba V, Yabukarski F, Herschlag D.

J Am Chem Soc. 2017 Aug 16;139(32):11089-11095. doi: 10.1021/jacs.7b03547. Epub 2017 Aug 2.

PMID:
28719738
3.

Learning gene regulatory networks from next generation sequencing data.

Jia B, Xu S, Xiao G, Lamba V, Liang F.

Biometrics. 2017 Dec;73(4):1221-1230. doi: 10.1111/biom.12682. Epub 2017 Mar 10.

4.

Kemp Eliminase Activity of Ketosteroid Isomerase.

Lamba V, Sanchez E, Fanning LR, Howe K, Alvarez MA, Herschlag D, Forconi M.

Biochemistry. 2017 Jan 31;56(4):582-591. doi: 10.1021/acs.biochem.6b00762. Epub 2017 Jan 20.

5.

Evaluation of the Catalytic Contribution from a Positioned General Base in Ketosteroid Isomerase.

Lamba V, Yabukarski F, Pinney M, Herschlag D.

J Am Chem Soc. 2016 Aug 10;138(31):9902-9. doi: 10.1021/jacs.6b04796. Epub 2016 Jul 27.

PMID:
27410422
6.

STAT5A and STAT5B have opposite correlations with drug response gene expression.

Lamba V, Jia B, Liang F.

Biochem Biophys Res Commun. 2016 Oct 14;479(2):117-124. doi: 10.1016/j.bbrc.2016.06.011. Epub 2016 Jun 3.

7.

MicroRNA-mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients.

Bhise NS, Chauhan L, Shin M, Cao X, Pounds S, Lamba V, Lamba JK.

Front Pharmacol. 2016 Jan 28;6:324. doi: 10.3389/fphar.2015.00324. eCollection 2015.

8.

BIOPHYSICS. Comment on "Extreme electric fields power catalysis in the active site of ketosteroid isomerase".

Natarajan A, Yabukarski F, Lamba V, Schwans JP, Sunden F, Herschlag D.

Science. 2015 Aug 28;349(6251):936. doi: 10.1126/science.aab1584. Epub 2015 Aug 27.

9.

Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-Containing Conditioning and Autologous Transplantation for Lymphoma.

Bachanova V, Shanley R, Malik F, Chauhan L, Lamba V, Weisdorf DJ, Burns LJ, Lamba JK.

Biol Blood Marrow Transplant. 2015 May;21(5):944-8. doi: 10.1016/j.bbmt.2015.02.001. Epub 2015 Feb 10.

10.

Identification of suitable reference genes for hepatic microRNA quantitation.

Lamba V, Ghodke-Puranik Y, Guan W, Lamba JK.

BMC Res Notes. 2014 Mar 7;7:129. doi: 10.1186/1756-0500-7-129.

11.

microRNA-34a is associated with expression of key hepatic transcription factors and cytochromes P450.

Lamba V, Ghodke Y, Guan W, Tracy TS.

Biochem Biophys Res Commun. 2014 Mar 7;445(2):404-11. doi: 10.1016/j.bbrc.2014.02.024. Epub 2014 Feb 12.

12.

PharmGKB summary: mycophenolic acid pathway.

Lamba V, Sangkuhl K, Sanghavi K, Fish A, Altman RB, Klein TE.

Pharmacogenet Genomics. 2014 Jan;24(1):73-9. doi: 10.1097/FPC.0000000000000010. Review. No abstract available.

13.

Feasibility of an electronic stethoscope system for monitoring neonatal bowel sounds.

Dumas J, Hill KM, Adrezin RS, Alba J, Curry R, Campagna E, Fernandes C, Lamba V, Eisenfeld L.

Conn Med. 2013 Sep;77(8):467-71.

PMID:
24156174
14.

New directions in targeting protein kinases: focusing upon true allosteric and bivalent inhibitors.

Lamba V, Ghosh I.

Curr Pharm Des. 2012;18(20):2936-45. Review.

PMID:
22571662
15.

Using PharmGKB to train text mining approaches for identifying potential gene targets for pharmacogenomic studies.

Pakhomov S, McInnes BT, Lamba J, Liu Y, Melton GB, Ghodke Y, Bhise N, Lamba V, Birnbaum AK.

J Biomed Inform. 2012 Oct;45(5):862-9. doi: 10.1016/j.jbi.2012.04.007. Epub 2012 May 4.

16.

Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium.

Jacobson PA, Schladt D, Israni A, Oetting WS, Lin YC, Leduc R, Guan W, Lamba V, Matas AJ; DeKAF Investigators.

Transplantation. 2012 Mar 27;93(6):624-31. doi: 10.1097/TP.0b013e3182461288.

17.

Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes.

Lamba JK, Crews KR, Pounds SB, Cao X, Gandhi V, Plunkett W, Razzouk BI, Lamba V, Baker SD, Raimondi SC, Campana D, Pui CH, Downing JR, Rubnitz JE, Ribeiro RC.

Pharmacogenomics. 2011 Mar;12(3):327-39. doi: 10.2217/pgs.10.191.

18.

Designing molecular devices by altering bond lengths.

Lamba V, Wilkinson SJ, Arora C.

J Mol Model. 2011 Dec;17(12):3251-5. doi: 10.1007/s00894-011-1013-8. Epub 2011 Mar 4.

PMID:
21369931
19.

Novel polymorphisms associated with tacrolimus trough concentrations: results from a multicenter kidney transplant consortium.

Jacobson PA, Oetting WS, Brearley AM, Leduc R, Guan W, Schladt D, Matas AJ, Lamba V, Julian BA, Mannon RB, Israni A; DeKAF Investigators.

Transplantation. 2011 Feb 15;91(3):300-8. doi: 10.1097/TP.0b013e318200e991.

20.

Genetic determinants of mycophenolate-related anemia and leukopenia after transplantation.

Jacobson PA, Schladt D, Oetting WS, Leduc R, Guan W, Matas AJ, Lamba V, Mannon RB, Julian BA, Israni A; DeKAF investigators.

Transplantation. 2011 Feb 15;91(3):309-16. doi: 10.1097/TP.0b013e318200e971.

21.

Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation.

Israni A, Leduc R, Holmes J, Jacobson PA, Lamba V, Guan W, Schladt D, Chen J, Matas AJ, Oetting WS; DeKAF Investigators.

Transplantation. 2010 Dec 27;90(12):1401-8. doi: 10.1097/TP.0b013e3182000085.

22.

PharmGKB summary: very important pharmacogene information for CYP2B6.

Thorn CF, Lamba JK, Lamba V, Klein TE, Altman RB.

Pharmacogenet Genomics. 2010 Aug;20(8):520-3. No abstract available.

23.

Genetic predictors of interindividual variability in hepatic CYP3A4 expression.

Lamba V, Panetta JC, Strom S, Schuetz EG.

J Pharmacol Exp Ther. 2010 Mar;332(3):1088-99. doi: 10.1124/jpet.109.160804. Epub 2009 Nov 24.

24.

Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.

Perera MA, Thirumaran RK, Cox NJ, Hanauer S, Das S, Brimer-Cline C, Lamba V, Schuetz EG, Ratain MJ, Di Rienzo A.

Pharmacogenomics J. 2009 Feb;9(1):49-60. doi: 10.1038/tpj.2008.13. Epub 2008 Sep 30.

25.

Pharmacogenetic pathway analysis of docetaxel elimination.

Baker SD, Verweij J, Cusatis GA, van Schaik RH, Marsh S, Orwick SJ, Franke RM, Hu S, Schuetz EG, Lamba V, Messersmith WA, Wolff AC, Carducci MA, Sparreboom A.

Clin Pharmacol Ther. 2009 Feb;85(2):155-63. doi: 10.1038/clpt.2008.95. Epub 2008 May 28.

26.

Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.

Lamba J, Lamba V, Strom S, Venkataramanan R, Schuetz E.

Drug Metab Dispos. 2008 Jan;36(1):169-81. Epub 2007 Oct 9.

PMID:
17925385
27.

ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics.

Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E.

Xenobiotica. 2006 Oct-Nov;36(10-11):989-1012.

PMID:
17118917
28.

MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.

Lamba J, Strom S, Venkataramanan R, Thummel KE, Lin YS, Liu W, Cheng C, Lamba V, Watkins PB, Schuetz E.

Clin Pharmacol Ther. 2006 Apr;79(4):325-38. Epub 2006 Feb 20.

PMID:
16580901
29.

Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.

Mouly SJ, Matheny C, Paine MF, Smith G, Lamba J, Lamba V, Pusek SN, Schuetz EG, Stewart PW, Watkins PB.

Clin Pharmacol Ther. 2005 Dec;78(6):605-18.

PMID:
16338276
30.

Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics.

Lamba J, Lamba V, Schuetz E.

Curr Drug Metab. 2005 Aug;6(4):369-83. Review.

PMID:
16101575
31.

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.

Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):251-65.

PMID:
15364541
32.

Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences.

Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, Schuetz E.

J Pharmacol Exp Ther. 2004 Nov;311(2):811-21. Epub 2004 Jun 11.

PMID:
15194709
33.

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.

Lamba V, Lamba J, Yasuda K, Strom S, Davila J, Hancock ML, Fackenthal JD, Rogan PK, Ring B, Wrighton SA, Schuetz EG.

J Pharmacol Exp Ther. 2003 Dec;307(3):906-22. Epub 2003 Oct 9.

PMID:
14551287
34.

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB.

Nat Med. 2003 Feb;9(2):220-4. Epub 2003 Jan 6.

PMID:
12514743
35.

Genetic polymorphism of CYP2D6 in North Indian subjects.

Lamba V, Lamba JK, Dilawari JB, Kohli KK.

Eur J Clin Pharmacol. 1998 Nov-Dec;54(9-10):787-91.

PMID:
9923585
36.
38.

Role of testosterone, estradiol-17 beta, and cortisol during vitellogenin synthesis in the catfish, Heteropneustes fossilis (Bloch).

Sundararaj BI, Goswami SV, Lamba VJ.

Gen Comp Endocrinol. 1982 Nov;48(3):390-7. No abstract available.

PMID:
7152240
39.

Radioimmunoassay for plasma cortisol, testosterone, estradiol-17 beta, and estrone in the catfish Heteropneustes fossilis (Bloch): development and validation.

Lamba VJ, Goswami SV, Sundararaj BI.

Gen Comp Endocrinol. 1982 Jun;47(2):170-81. No abstract available.

PMID:
7095414
40.

Some aspects of oocyte maturation in catfish.

Sundararaj BI, Goswami SV, Lamba V.

J Steroid Biochem. 1979 Jul;11(1C):701-7. No abstract available.

PMID:
491639

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