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Items: 1 to 50 of 235


The importance of different frailty domains in a population based sample in England.

Arnadottir SA, Bruce J, Lall R, Withers EJ, Underwood M, Shaw F, Sheridan R, Hossain A, Lamb SE; Pre-FIT Study Group.

BMC Geriatr. 2020 Jan 15;20(1):16. doi: 10.1186/s12877-019-1411-9.


Bayesian adaptive designs for multi-arm trials: an orthopaedic case study.

Ryan EG, Lamb SE, Williamson E, Gates S.

Trials. 2020 Jan 14;21(1):83. doi: 10.1186/s13063-019-4021-0.


Platelet-rich plasma injection for adults with acute Achilles tendon rupture: the PATH-2 RCT.

Alsousou J, Keene DJ, Harrison P, Hulley P, Wagland S, Thompson JY, Parsons SR, Byrne C, Schlüssel MM, O’Connor HM, Dutton SJ, Lamb SE, Willett K.

Southampton (UK): NIHR Journals Library; 2019 Nov.


Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial.

Keene DJ, Alsousou J, Harrison P, Hulley P, Wagland S, Parsons SR, Thompson JY, O'Connor HM, Schlüssel MM, Dutton SJ, Lamb SE, Willett K; PATH-2 trial group.

BMJ. 2019 Nov 20;367:l6132. doi: 10.1136/bmj.l6132.


Short and long-term clinical effectiveness and cost-effectiveness of a late-phase community-based balance and gait exercise program following hip fracture. The EVA-Hip Randomised Controlled Trial.

Taraldsen K, Thingstad P, Døhl Ø, Follestad T, Helbostad JL, Lamb SE, Saltvedt I, Sletvold O, Halsteinli V.

PLoS One. 2019 Nov 18;14(11):e0224971. doi: 10.1371/journal.pone.0224971. eCollection 2019.


Physiotherapy rehabilitation for osteoporotic vertebral fracture-a randomised controlled trial and economic evaluation (PROVE trial).

Barker KL, Newman M, Stallard N, Leal J, Lowe CM, Javaid MK, Noufaily A, Hughes T, Smith D, Gandhi V, Cooper C, Lamb SE; PROVE trial group.

Osteoporos Int. 2019 Nov 12. doi: 10.1007/s00198-019-05133-0. [Epub ahead of print]


Cost-effectiveness of negative-pressure wound therapy in adults with severe open fractures of the lower limb: evidence from the WOLLF randomized controlled trial.

Petrou S, Parker B, Masters J, Achten J, Bruce J, Lamb SE, Parsons N, Costa ML; WOLLF Trial Collaborators.

Bone Joint J. 2019 Nov;101-B(11):1392-1401. doi: 10.1302/0301-620X.101B11.BJJ-2018-1228.R2.


Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT.

Perkins GD, Mistry D, Lall R, Gao-Smith F, Snelson C, Hart N, Camporota L, Varley J, Carle C, Paramasivam E, Hoddell B, de Paeztron A, Dosanjh S, Sampson J, Blair L, Couper K, McAuley D, Young JD, Walsh T, Blackwood B, Rose L, Lamb SE, Dritsaki M, Maredza M, Khan I, Petrou S, Gates S.

Health Technol Assess. 2019 Sep;23(48):1-114. doi: 10.3310/hta23480.


Inadequate description of placebo and sham controls in a systematic review of recent trials.

Webster RK, Howick J, Hoffmann T, Macdonald H, Collins GS, Rees JL, Napadow V, Madigan C, Price A, Lamb SE, Bishop FL, Bokelmann K, Papanikitas A, Roberts N, Evers AWM.

Eur J Clin Invest. 2019 Nov;49(11):e13169. doi: 10.1111/eci.13169. Epub 2019 Sep 30.


Exercise or manual physiotherapy compared with a single session of physiotherapy for osteoporotic vertebral fracture: three-arm PROVE RCT.

Barker KL, Newman M, Stallard N, Leal J, Minns Lowe C, Javaid MK, Noufaily A, Adhikari A, Hughes T, Smith DJ, Gandhi V, Cooper C, Lamb SE.

Health Technol Assess. 2019 Aug;23(44):1-318. doi: 10.3310/hta23440.


Investigating causal mechanisms in randomised controlled trials.

Lee H, Herbert RD, Lamb SE, Moseley AM, McAuley JH.

Trials. 2019 Aug 23;20(1):524. doi: 10.1186/s13063-019-3593-z.


Percutaneous fixation with Kirschner wires versus volar locking-plate fixation in adults with dorsally displaced fracture of distal radius: five-year follow-up of a randomized controlled trial.

Costa ML, Achten J, Rangan A, Lamb SE, Parsons NR.

Bone Joint J. 2019 Aug;101-B(8):978-983. doi: 10.1302/0301-620X.101B8.BJJ-2018-1285.R1.


Caregiver Interventions for Adults Discharged from the Hospital: Systematic Review and Meta-Analysis.

Smith TO, Pearson M, Pfeiffer K, Crotty M, Lamb SE.

J Am Geriatr Soc. 2019 Sep;67(9):1960-1969. doi: 10.1111/jgs.16048. Epub 2019 Jul 27. Review.


Predicting patient-reported and objectively measured functional outcome 6 months after ankle fracture in people aged 60 years or over in the UK: prognostic model development and internal validation.

Keene DJ, Vadher K, Willett K, Mistry D, Costa ML, Collins GS, Lamb SE.

BMJ Open. 2019 Jul 23;9(7):e029813. doi: 10.1136/bmjopen-2019-029813.


Exercise- and strategy-based physiotherapy-delivered intervention for preventing repeat falls in people with Parkinson's: the PDSAFE RCT.

Ashburn A, Pickering R, McIntosh E, Hulbert S, Rochester L, Roberts HC, Nieuwboer A, Kunkel D, Goodwin VA, Lamb SE, Ballinger C, Seymour KC.

Health Technol Assess. 2019 Jul;23(36):1-150. doi: 10.3310/hta23360.


The different influence of high levels of physical activity on the incidence of knee OA in overweight and obese men and women-a gender specific analysis.

Soutakbar H, Lamb SE, Silman AJ.

Osteoarthritis Cartilage. 2019 Oct;27(10):1430-1436. doi: 10.1016/j.joca.2019.05.025. Epub 2019 Jul 18.


Caregiver-Delivered Stroke Rehabilitation in Rural China.

Zhou B, Zhang J, Zhao Y, Li X, Anderson CS, Xie B, Wang N, Zhang Y, Tang X, Prvu Bettger J, Chen S, Gu W, Luo R, Zhao Q, Li X, Sun Z, Lindley RI, Lamb SE, Wu Y, Shi J, Yan LL.

Stroke. 2019 Jul;50(7):1825-1830. doi: 10.1161/STROKEAHA.118.021558. Epub 2019 Jun 10.


Validation of a prospective cohort study of older adults with hip fractures.

Metcalfe D, Costa ML, Parsons NR, Achten J, Masters J, Png ME, Lamb SE, Griffin XL.

Bone Joint J. 2019 Jun;101-B(6):708-714. doi: 10.1302/0301-620X.101B6.BJJ-2018-1623.R1.


Factors associated with the magnitude of limitations during recovery from a fracture of the proximal humerus: predictors of limitations after proximal humerus fracture.

Jayakumar P, Teunis T, Williams M, Lamb SE, Ring D, Gwilym S.

Bone Joint J. 2019 Jun;101-B(6):715-723. doi: 10.1302/0301-620X.101B6.BJJ-2018-0857.R1.


Process evaluation of complex interventions tested in randomised controlled trials in musculoskeletal disorders: a systematic review protocol.

Ribeiro DC, Abbott JH, Sharma S, Lamb SE.

BMJ Open. 2019 May 19;9(5):e028160. doi: 10.1136/bmjopen-2018-028160.


Using Bayesian adaptive designs to improve phase III trials: a respiratory care example.

Ryan EG, Bruce J, Metcalfe AJ, Stallard N, Lamb SE, Viele K, Young D, Gates S.

BMC Med Res Methodol. 2019 May 14;19(1):99. doi: 10.1186/s12874-019-0739-3.


Treatment of first-time traumatic anterior shoulder dislocation: the UK TASH-D cohort study.

Rees JL, Shah A, Edwards K, Sanchez-Santos MT, Robinson DE, Delmestri A, Carr A, Arden N, Lamb SE, Rangan A, Judge A, Pinedo-Villanueva R, Holt T, Hopewell S, Prieto-Alhambra D, Collins G.

Health Technol Assess. 2019 Apr;23(18):1-104. doi: 10.3310/hta23180.


Duration of Treatment Effect Should Be Considered in the Design and Interpretation of Clinical Trials: Results of a Discrete Choice Experiment.

Copsey B, Buchanan J, Fitzpatrick R, Lamb SE, Dutton SJ, Cook JA.

Med Decis Making. 2019 May;39(4):461-473. doi: 10.1177/0272989X19841877. Epub 2019 Apr 8.


Multicentre, randomised controlled trial of PDSAFE, a physiotherapist-delivered fall prevention programme for people with Parkinson's.

Chivers Seymour K, Pickering R, Rochester L, Roberts HC, Ballinger C, Hulbert S, Kunkel D, Marian IR, Fitton C, McIntosh E, Goodwin VA, Nieuwboer A, Lamb SE, Ashburn A.

J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):774-782. doi: 10.1136/jnnp-2018-319448. Epub 2019 Apr 3.


Development and delivery of the BOOST (Better Outcomes for Older adults with Spinal Trouble) intervention for older adults with neurogenic claudication.

Ward L, Williamson E, Hansen Z, French DP, Boniface G, Rogers D, Lamb SE; Better Outcomes for Older Adults with Spinal Trouble BOOST Group.

Physiotherapy. 2019 Jun;105(2):262-274. doi: 10.1016/ Epub 2019 Feb 7.


Surgical fixation with K-wires versus plaster casting in the treatment of dorsally displaced distal radius fractures: protocol for Distal Radius Acute Fracture Fixation Trial 2 (DRAFFT 2).

Achten J, Sones W, Dias J, Hedley H, Cook JA, Dritsaki M, Png ME, Gray A, Lamb SE, Costa ML.

BMJ Open. 2019 Mar 23;9(3):e028474. doi: 10.1136/bmjopen-2018-028474.


An overview of systematic reviews found suboptimal reporting and methodological limitations of mediation studies investigating causal mechanisms.

Cashin AG, Lee H, Lamb SE, Hopewell S, Mansell G, Williams CM, Kamper SJ, Henschke N, McAuley JH.

J Clin Epidemiol. 2019 Jul;111:60-68.e1. doi: 10.1016/j.jclinepi.2019.03.005. Epub 2019 Mar 20. Review.


A study update newsletter or Post-it® note did not increase postal questionnaire response rates in a falls prevention trial: an embedded randomised factorial trial.

Rodgers S, Sbizzera I, Cockayne S, Fairhurst C, Lamb SE, Vernon W, Watson J, Hewitt C, Torgerson D.

Version 2. F1000Res. 2018 Jul 16 [revised 2019 Jan 1];7:1083. doi: 10.12688/f1000research.14591.2. eCollection 2018.


Effectiveness of scoliosis-specific exercises for adolescent idiopathic scoliosis compared with other non-surgical interventions: a systematic review and meta-analysis.

Thompson JY, Williamson EM, Williams MA, Heine PJ, Lamb SE; ACTIvATeS Study Group.

Physiotherapy. 2019 Jun;105(2):214-234. doi: 10.1016/ Epub 2018 Oct 27.


Exercise for preventing falls in older people living in the community.

Sherrington C, Fairhall NJ, Wallbank GK, Tiedemann A, Michaleff ZA, Howard K, Clemson L, Hopewell S, Lamb SE.

Cochrane Database Syst Rev. 2019 Jan 31;1:CD012424. doi: 10.1002/14651858.CD012424.pub2.


Negative-pressure wound therapy versus standard dressings for adults with an open lower limb fracture: the WOLLF RCT.

Costa ML, Achten J, Bruce J, Davis S, Hennings S, Willett K, Petrou S, Jeffery S, Griffin D, Parker B, Masters J, Lamb SE, Tutton E, Parsons N.

Health Technol Assess. 2018 Dec;22(73):1-162. doi: 10.3310/hta22730.


Effectiveness of cognitive-behavioural therapy: a protocol for an overview of systematic reviews and meta-analyses.

Fordham B, Sugavanam T, Hopewell S, Hemming K, Howick J, Kirtley S, das Nair R, Hamer-Hunt J, Lamb SE.

BMJ Open. 2018 Dec 14;8(12):e025761. doi: 10.1136/bmjopen-2018-025761.


Prognostic models for identifying risk of poor outcome in people with acute ankle sprains: the SPRAINED development and external validation study.

Keene DJ, Schlüssel MM, Thompson J, Hagan DA, Williams MA, Byrne C, Goodacre S, Cooke M, Gwilym S, Hormbrey P, Bostock J, Haywood K, Wilson D, Collins GS, Lamb SE.

Health Technol Assess. 2018 Nov;22(64):1-112. doi: 10.3310/hta22640.


Development and prospective external validation of a tool to predict poor recovery at 9 months after acute ankle sprain in UK emergency departments: the SPRAINED prognostic model.

Schlussel MM, Keene DJ, Collins GS, Bostock J, Byrne C, Goodacre S, Gwilym S, Hagan DA, Haywood K, Thompson J, Williams MA, Lamb SE; SPRAINED study team.

BMJ Open. 2018 Nov 5;8(11):e022802. doi: 10.1136/bmjopen-2018-022802.


Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial.

Perkins GD, Mistry D, Gates S, Gao F, Snelson C, Hart N, Camporota L, Varley J, Carle C, Paramasivam E, Hoddell B, McAuley DF, Walsh TS, Blackwood B, Rose L, Lamb SE, Petrou S, Young D, Lall R; Breathe Collaborators.

JAMA. 2018 Nov 13;320(18):1881-1888. doi: 10.1001/jama.2018.13763.


Better Outcomes for Older people with Spinal Trouble (BOOST) Trial: a randomised controlled trial of a combined physical and psychological intervention for older adults with neurogenic claudication, a protocol.

Williamson E, Ward L, Vadher K, Dutton SJ, Parker B, Petrou S, Hutchinson CE, Gagen R, Arden NK, Barker K, Boniface G, Bruce J, Collins G, Fairbank J, Fitch J, French DP, Garrett A, Gandhi V, Griffiths F, Hansen Z, Mallen C, Morris A, Lamb SE.

BMJ Open. 2018 Oct 18;8(10):e022205. doi: 10.1136/bmjopen-2018-022205.


Comparison of alternative falls data collection methods in the Prevention of Falls Injury Trial (PreFIT).

Griffin J, Lall R, Bruce J, Withers E, Finnegan S, Lamb SE; PreFIT Study Group.

J Clin Epidemiol. 2019 Feb;106:32-40. doi: 10.1016/j.jclinepi.2018.09.006. Epub 2018 Sep 25.


Problems persist in reporting of methods and results for the WOMAC measure in hip and knee osteoarthritis trials.

Copsey B, Thompson JY, Vadher K, Ali U, Dutton SJ, Fitzpatrick R, Lamb SE, Cook JA.

Qual Life Res. 2019 Feb;28(2):335-343. doi: 10.1007/s11136-018-1978-1. Epub 2018 Sep 18. Review.


Can occupational therapist-led home environmental assessment prevent falls in older people? A modified cohort randomised controlled trial protocol.

Cockayne S, Pighills A, Adamson J, Fairhurst C, Drummond A, Hewitt C, Rodgers S, Ronaldson SJ, Lamb SE, Crossland S, Boyes S, Gilbody S, Relton C, Torgerson DJ; OTIS study.

BMJ Open. 2018 Sep 10;8(9):e022488. doi: 10.1136/bmjopen-2018-022488.


Platelet-rich plasma in Achilles tendon healing 2 (PATH-2) trial: statistical analysis plan for a multicentre, double-blinded, parallel-group, placebo-controlled randomised clinical trial.

Schlüssel MM, Keene DJ, Wagland S, Alsousou J, Lamb SE, Willett K, Dutton SJ; PATH-2 Trial Study Group.

Trials. 2018 Aug 29;19(1):464. doi: 10.1186/s13063-018-2840-z.


Sample size calculations are poorly conducted and reported in many randomized trials of hip and knee osteoarthritis: results of a systematic review.

Copsey B, Thompson JY, Vadher K, Ali U, Dutton SJ, Fitzpatrick R, Lamb SE, Cook JA.

J Clin Epidemiol. 2018 Dec;104:52-61. doi: 10.1016/j.jclinepi.2018.08.013. Epub 2018 Aug 23. Review.


Exercise for rheumatoid arthritis of the hand.

Williams MA, Srikesavan C, Heine PJ, Bruce J, Brosseau L, Hoxey-Thomas N, Lamb SE.

Cochrane Database Syst Rev. 2018 Jul 31;7:CD003832. doi: 10.1002/14651858.CD003832.pub3. Review.


Multifactorial and multiple component interventions for preventing falls in older people living in the community.

Hopewell S, Adedire O, Copsey BJ, Boniface GJ, Sherrington C, Clemson L, Close JC, Lamb SE.

Cochrane Database Syst Rev. 2018 Jul 23;7:CD012221. doi: 10.1002/14651858.CD012221.pub2. Review.


Do portable nursing stations within bays of hospital wards reduce the rate of inpatient falls? An interrupted time-series analysis.

Ali UM, Judge A, Foster C, Brooke A, James K, Marriott T, Lamb SE.

Age Ageing. 2018 Nov 1;47(6):818-824. doi: 10.1093/ageing/afy097.


Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial.

Nanchahal J, Ball C, Davidson D, Williams L, Sones W, McCann FE, Cabrita M, Swettenham J, Cahoon NJ, Copsey B, Anne Francis E, Taylor PC, Black J, Barber VS, Dutton S, Feldmann M, Lamb SE.

EBioMedicine. 2018 Jul;33:282-288. doi: 10.1016/j.ebiom.2018.06.022. Epub 2018 Jul 6.


An Online Hand Exercise Intervention for Adults With Rheumatoid Arthritis (mySARAH): Design, Development, and Usability Testing.

Srikesavan C, Williamson E, Cranston T, Hunter J, Adams J, Lamb SE.

J Med Internet Res. 2018 Jun 27;20(6):e10457. doi: 10.2196/10457.


Cost-Effectiveness of a Multifaceted Podiatry Intervention for the Prevention of Falls in Older People: The REducing Falls with Orthoses and a Multifaceted Podiatry Intervention Trial Findings.

Corbacho B, Cockayne S, Fairhurst C, Hewitt CE, Hicks K, Kenan AM, Lamb SE, MacIntosh C, Menz HB, Redmond AC, Rodgers S, Scantlebury A, Watson J, Torgerson DJ; on behalf of the REFORM study.

Gerontology. 2018;64(5):503-512. doi: 10.1159/000489171. Epub 2018 Jun 26.


Participation in a trial in the emergency situation: a qualitative study of patient experience in the UK WOLLF trial.

Tutton E, Achten J, Lamb SE, Willett K, Costa ML; UK WOLLF Research Collaborators.

Trials. 2018 Jun 25;19(1):328. doi: 10.1186/s13063-018-2722-4.


Development of an exercise intervention for the prevention of musculoskeletal shoulder problems after breast cancer treatment: the prevention of shoulder problems trial (UK PROSPER).

Richmond H, Lait C, Srikesavan C, Williamson E, Moser J, Newman M, Betteley L, Fordham B, Rees S, Lamb SE, Bruce J; PROSPER Study Group.

BMC Health Serv Res. 2018 Jun 18;18(1):463. doi: 10.1186/s12913-018-3280-x.

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