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Items: 1 to 50 of 284

1.

Strategies, Setbacks, and Successes in the Synthesis of (-)-Spiroleucettadine.

Lamb RA, Lucas NT, Lessene G, Hawkins BC.

J Org Chem. 2018 Sep 7;83(17):10120-10133. doi: 10.1021/acs.joc.8b01404. Epub 2018 Jul 26.

PMID:
30003773
2.

Taxonomy of the order Mononegavirales: update 2018.

Amarasinghe GK, Aréchiga Ceballos NG, Banyard AC, Basler CF, Bavari S, Bennett AJ, Blasdell KR, Briese T, Bukreyev A, Caì Y, Calisher CH, Campos Lawson C, Chandran K, Chapman CA, Chiu CY, Choi KS, Collins PL, Dietzgen RG, Dolja VV, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Echevarría JE, Fooks AR, Formenty PBH, Fouchier RAM, Freuling CM, Ghedin E, Goldberg TL, Hewson R, Horie M, Hyndman TH, Jiāng D, Kityo R, Kobinger GP, Kondō H, Koonin EV, Krupovic M, Kurath G, Lamb RA, Lee B, Leroy EM, Maes P, Maisner A, Marston DA, Mor SK, Müller T, Mühlberger E, Ramírez VMN, Netesov SV, Ng TFF, Nowotny N, Palacios G, Patterson JL, Pawęska JT, Payne SL, Prieto K, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Siddell S, Smither SJ, Song Q, Song T, Stenglein MD, Stone DM, Takada A, Tesh RB, Thomazelli LM, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Vázquez-Morón S, Verdugo C, Volchkov VE, Wahl V, Walker PJ, Wang D, Wang LF, Wellehan JFX, Wiley MR, Whitfield AE, Wolf YI, Yè G, Zhāng YZ, Kuhn JH.

Arch Virol. 2018 Aug;163(8):2283-2294. doi: 10.1007/s00705-018-3814-x. Epub 2018 Apr 11.

PMID:
29637429
3.

Problems of classification in the family Paramyxoviridae.

Rima B, Collins P, Easton A, Fouchier R, Kurath G, Lamb RA, Lee B, Maisner A, Rota P, Wang LF.

Arch Virol. 2018 May;163(5):1395-1404. doi: 10.1007/s00705-018-3720-2. Epub 2018 Jan 25.

PMID:
29372404
4.

Structure of the Paramyxovirus Parainfluenza Virus 5 Nucleoprotein in Complex with an Amino-Terminal Peptide of the Phosphoprotein.

Aggarwal M, Leser GP, Kors CA, Lamb RA.

J Virol. 2018 Feb 12;92(5). pii: e01304-17. doi: 10.1128/JVI.01304-17. Print 2018 Mar 1.

5.

ICTV Virus Taxonomy Profile: Pneumoviridae.

Rima B, Collins P, Easton A, Fouchier R, Kurath G, Lamb RA, Lee B, Maisner A, Rota P, Wang L, Ictv Report Consortium.

J Gen Virol. 2017 Dec;98(12):2912-2913. doi: 10.1099/jgv.0.000959. Epub 2017 Oct 31.

6.

Towards industrial ultrafast laser microwelding: SiO2 and BK7 to aluminum alloy.

Carter RM, Troughton M, Chen J, Elder I, Thomson RR, Daniel Esser MJ, Lamb RA, Hand DP.

Appl Opt. 2017 Jun 1;56(16):4873-4881. doi: 10.1364/AO.56.004873.

PMID:
29047628
7.

Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation.

Wong JJW, Young TA, Zhang J, Liu S, Leser GP, Komives EA, Lamb RA, Zhou ZH, Salafsky J, Jardetzky TS.

Nat Commun. 2017 Oct 3;8(1):781. doi: 10.1038/s41467-017-00863-3.

8.

Total Synthesis of (-)-Spiroleucettadine.

Lamb RA, Aberle NS, Lucas NT, Lessene G, Hawkins BC.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14663-14666. doi: 10.1002/anie.201708110. Epub 2017 Oct 20.

PMID:
28960638
9.

Single-photon three-dimensional imaging at up to 10 kilometers range.

Pawlikowska AM, Halimi A, Lamb RA, Buller GS.

Opt Express. 2017 May 15;25(10):11919-11931. doi: 10.1364/OE.25.011919.

PMID:
28788749
10.

Taxonomy of the order Mononegavirales: update 2017.

Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RAM, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiāng D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH.

Arch Virol. 2017 Aug;162(8):2493-2504. doi: 10.1007/s00705-017-3311-7. Epub 2017 Apr 7.

11.

Lateral Organization of Influenza Virus Proteins in the Budozone Region of the Plasma Membrane.

Leser GP, Lamb RA.

J Virol. 2017 Apr 13;91(9). pii: e02104-16. doi: 10.1128/JVI.02104-16. Print 2017 May 1.

12.

Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus.

Wen X, Mousa JJ, Bates JT, Lamb RA, Crowe JE Jr, Jardetzky TS.

Nat Microbiol. 2017 Jan 30;2:16272. doi: 10.1038/nmicrobiol.2016.272.

13.

Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials.

Postler TS, Clawson AN, Amarasinghe GK, Basler CF, Bavari S, Benko M, Blasdell KR, Briese T, Buchmeier MJ, Bukreyev A, Calisher CH, Chandran K, Charrel R, Clegg CS, Collins PL, Juan Carlos T, Derisi JL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Emonet S, Formenty P, Fouchier RAM, Ghedin E, Gonzalez JP, Harrach B, Hewson R, Horie M, Jiang D, Kobinger G, Kondo H, Kropinski AM, Krupovic M, Kurath G, Lamb RA, Leroy EM, Lukashevich IS, Maisner A, Mushegian AR, Netesov SV, Nowotny N, Patterson JL, Payne SL, PaWeska JT, Peters CJ, Radoshitzky SR, Rima BK, Romanowski V, Rubbenstroth D, Sabanadzovic S, Sanfaçon H, Salvato MS, Schwemmle M, Smither SJ, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang LF, Varsani A, Whitfield AE, Zerbini FM, Kuhn JH.

Syst Biol. 2017 May 1;66(3):463-473. doi: 10.1093/sysbio/syw096.

14.

Flexibility of the Head-Stalk Linker Domain of Paramyxovirus HN Glycoprotein Is Essential for Triggering Virus Fusion.

Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA.

J Virol. 2016 Sep 29;90(20):9172-81. doi: 10.1128/JVI.01187-16. Print 2016 Oct 15.

15.

Immobilization of the N-terminal helix stabilizes prefusion paramyxovirus fusion proteins.

Song AS, Poor TA, Abriata LA, Jardetzky TS, Dal Peraro M, Lamb RA.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3844-51. doi: 10.1073/pnas.1608349113. Epub 2016 Jun 22.

16.

Mutagenesis of Paramyxovirus Hemagglutinin-Neuraminidase Membrane-Proximal Stalk Region Influences Stability, Receptor Binding, and Neuraminidase Activity.

Adu-Gyamfi E, Kim LS, Jardetzky TS, Lamb RA.

J Virol. 2016 Aug 12;90(17):7778-88. doi: 10.1128/JVI.00896-16. Print 2016 Sep 1.

17.

A Chimeric Pneumovirus Fusion Protein Carrying Neutralizing Epitopes of Both MPV and RSV.

Wen X, Pickens J, Mousa JJ, Leser GP, Lamb RA, Crowe JE Jr, Jardetzky TS.

PLoS One. 2016 May 25;11(5):e0155917. doi: 10.1371/journal.pone.0155917. eCollection 2016.

18.

Taxonomy of the order Mononegavirales: update 2016.

Afonso CL, Amarasinghe GK, Bányai K, Bào Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Chéng J, Clawson AN, Collins PL, Dietzgen RG, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Farkas SL, Freitas-Astúa J, Formenty P, Fouchier RA, Fù Y, Ghedin E, Goodin MM, Hewson R, Horie M, Hyndman TH, Jiāng D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lenardon S, Leroy EM, Li CX, Lin XD, Liú L, Longdon B, Marton S, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Randall RE, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Shi M, Smither SJ, Stenglein MD, Stone DM, Takada A, Terregino C, Tesh RB, Tian JH, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Verbeek M, Volchkov VE, Wahl-Jensen V, Walsh JA, Walker PJ, Wang D, Wang LF, Wetzel T, Whitfield AE, Xiè JT, Yuen KY, Zhang YZ, Kuhn JH.

Arch Virol. 2016 Aug;161(8):2351-60. doi: 10.1007/s00705-016-2880-1. Epub 2016 May 23.

19.

Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form.

Wong JJ, Paterson RG, Lamb RA, Jardetzky TS.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1056-61. doi: 10.1073/pnas.1523303113. Epub 2015 Dec 28.

20.

Type II integral membrane protein, TM of J paramyxovirus promotes cell-to-cell fusion.

Li Z, Hung C, Paterson RG, Michel F, Fuentes S, Place R, Lin Y, Hogan RJ, Lamb RA, He B.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12504-9. doi: 10.1073/pnas.1509476112. Epub 2015 Sep 21.

21.

In memoriam--Richard M. Elliott (1954-2015).

Brennan B, Weber F, Kormelink R, Schnettler E, Bouloy M, Failloux AB, Weaver SC, Fazakerley JK, Fragkoudis R, Harris M, Barr JN, Palese P, García-Sastre A, Dalziel RG, Dutia BM, Lowen AC, Steel J, Randall RE, Paul Duprex W, Rice CM, Tesh RB, Murphy FA, Ebihara H, Vasconcelos PF, Nunes MR, Fooks AR, Smith GL, Goodfellow I, Pappu HR, Lamb RA, Paterson RG, Higgs S, Vanlandingham DL, Dietzgen RG, Stephen Lodmell J, Nichol ST, Daly J, Ullman DE, Plyusnin A, Plyusnina A, Efstathiou S, Hewson R, Tordo N, Cherry S, Boutell C, Hosie MJ, Murcia PR, Neil JC, Palmarini M, Patel AH, Willett BJ, Kohl A, McLauchlan J.

J Gen Virol. 2015 Aug;96(8):1975-8. doi: 10.1099/jgv.0.000241. No abstract available.

22.

Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex.

Alayyoubi M, Leser GP, Kors CA, Lamb RA.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1792-9. doi: 10.1073/pnas.1503941112. Epub 2015 Mar 23.

23.

Timing is everything: Fine-tuned molecular machines orchestrate paramyxovirus entry.

Bose S, Jardetzky TS, Lamb RA.

Virology. 2015 May;479-480:518-31. doi: 10.1016/j.virol.2015.02.037. Epub 2015 Mar 12. Review.

24.

On the stability of parainfluenza virus 5 F proteins.

Poor TA, Song AS, Welch BD, Kors CA, Jardetzky TS, Lamb RA.

J Virol. 2015 Mar;89(6):3438-41. doi: 10.1128/JVI.03221-14. Epub 2015 Jan 14.

25.

Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.

Wu Y, Canturk B, Jo H, Ma C, Gianti E, Klein ML, Pinto LH, Lamb RA, Fiorin G, Wang J, DeGrado WF.

J Am Chem Soc. 2014 Dec 31;136(52):17987-95. doi: 10.1021/ja508461m. Epub 2014 Dec 18.

26.

Influenza A virus uses intercellular connections to spread to neighboring cells.

Roberts KL, Manicassamy B, Lamb RA.

J Virol. 2015 Feb;89(3):1537-49. doi: 10.1128/JVI.03306-14. Epub 2014 Nov 26.

27.

The innate immune sensor LGP2 activates antiviral signaling by regulating MDA5-RNA interaction and filament assembly.

Bruns AM, Leser GP, Lamb RA, Horvath CM.

Mol Cell. 2014 Sep 4;55(5):771-81. doi: 10.1016/j.molcel.2014.07.003. Epub 2014 Aug 7.

28.

Probing the functions of the paramyxovirus glycoproteins F and HN with a panel of synthetic antibodies.

Welch BD, Paduch M, Leser GP, Bergman Z, Kors CA, Paterson RG, Jardetzky TS, Kossiakoff AA, Lamb RA.

J Virol. 2014 Oct;88(20):11713-25. doi: 10.1128/JVI.01707-14. Epub 2014 Aug 13.

29.

Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus.

Rey-Carrizo M, Barniol-Xicota M, Ma C, Frigolé-Vivas M, Torres E, Naesens L, Llabrés S, Juárez-Jiménez J, Luque FJ, DeGrado WF, Lamb RA, Pinto LH, Vázquez S.

J Med Chem. 2014 Jul 10;57(13):5738-47. doi: 10.1021/jm5005804. Epub 2014 Jun 30.

30.

Probing the paramyxovirus fusion (F) protein-refolding event from pre- to postfusion by oxidative footprinting.

Poor TA, Jones LM, Sood A, Leser GP, Plasencia MD, Rempel DL, Jardetzky TS, Woods RJ, Gross ML, Lamb RA.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2596-605. doi: 10.1073/pnas.1408983111. Epub 2014 Jun 9.

31.

Activation of paramyxovirus membrane fusion and virus entry.

Jardetzky TS, Lamb RA.

Curr Opin Virol. 2014 Apr;5:24-33. doi: 10.1016/j.coviro.2014.01.005. Epub 2014 Feb 16. Review.

32.

Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cells.

Bose S, Song AS, Jardetzky TS, Lamb RA.

J Virol. 2014 Apr;88(8):3925-41. doi: 10.1128/JVI.03741-13. Epub 2014 Jan 22.

33.

3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.

Rey-Carrizo M, Torres E, Ma C, Barniol-Xicota M, Wang J, Wu Y, Naesens L, DeGrado WF, Lamb RA, Pinto LH, Vázquez S.

J Med Chem. 2013 Nov 27;56(22):9265-74. doi: 10.1021/jm401340p. Epub 2013 Nov 15.

34.

Asp44 stabilizes the Trp41 gate of the M2 proton channel of influenza A virus.

Ma C, Fiorin G, Carnevale V, Wang J, Lamb RA, Klein ML, Wu Y, Pinto LH, DeGrado WF.

Structure. 2013 Nov 5;21(11):2033-41. doi: 10.1016/j.str.2013.08.029. Epub 2013 Oct 17.

35.

Viral membrane scission.

Rossman JS, Lamb RA.

Annu Rev Cell Dev Biol. 2013;29:551-69. doi: 10.1146/annurev-cellbio-101011-155838. Epub 2013 May 31. Review.

36.

Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastability.

Bose S, Heath CM, Shah PA, Alayyoubi M, Jardetzky TS, Lamb RA.

J Virol. 2013 Dec;87(24):13520-31. doi: 10.1128/JVI.02123-13. Epub 2013 Oct 2.

37.

Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain.

Welch BD, Yuan P, Bose S, Kors CA, Lamb RA, Jardetzky TS.

PLoS Pathog. 2013;9(8):e1003534. doi: 10.1371/journal.ppat.1003534. Epub 2013 Aug 8.

38.

The amphipathic helix of influenza A virus M2 protein is required for filamentous bud formation and scission of filamentous and spherical particles.

Roberts KL, Leser GP, Ma C, Lamb RA.

J Virol. 2013 Sep;87(18):9973-82. doi: 10.1128/JVI.01363-13. Epub 2013 Jul 10.

39.

Deadly H7N9 influenza virus: a pandemic in the making or a warning lesson?

Lamb RA.

Am J Respir Crit Care Med. 2013 Jul 1;188(1):1-2. doi: 10.1164/rccm.201305-0914ED. No abstract available.

40.

Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.

Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF.

J Med Chem. 2013 Apr 11;56(7):2804-12. doi: 10.1021/jm301538e. Epub 2013 Mar 27.

41.

Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay.

Balgi AD, Wang J, Cheng DY, Ma C, Pfeifer TA, Shimizu Y, Anderson HJ, Pinto LH, Lamb RA, DeGrado WF, Roberge M.

PLoS One. 2013;8(2):e55271. doi: 10.1371/journal.pone.0055271. Epub 2013 Feb 1.

42.

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus.

Wang J, Wu Y, Ma C, Fiorin G, Wang J, Pinto LH, Lamb RA, Klein ML, Degrado WF.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1315-20. doi: 10.1073/pnas.1216526110. Epub 2013 Jan 9.

43.

Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein.

Welch BD, Liu Y, Kors CA, Leser GP, Jardetzky TS, Lamb RA.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16672-7. doi: 10.1073/pnas.1213802109. Epub 2012 Sep 10.

44.

Reversible inhibition of fusion activity of a paramyxovirus fusion protein by an engineered disulfide bond in the membrane-proximal external region.

Zokarkar A, Connolly SA, Jardetzky TS, Lamb RA.

J Virol. 2012 Nov;86(22):12397-401. doi: 10.1128/JVI.02006-12. Epub 2012 Sep 5.

45.

Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering.

Bose S, Zokarkar A, Welch BD, Leser GP, Jardetzky TS, Lamb RA.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2625-34. Epub 2012 Sep 4.

46.

Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.

Yuan P, Paterson RG, Leser GP, Lamb RA, Jardetzky TS.

PLoS Pathog. 2012;8(8):e1002855. doi: 10.1371/journal.ppat.1002855. Epub 2012 Aug 9.

47.

Filamentous influenza virus enters cells via macropinocytosis.

Rossman JS, Leser GP, Lamb RA.

J Virol. 2012 Oct;86(20):10950-60. Epub 2012 Aug 8.

48.

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site.

Wen X, Krause JC, Leser GP, Cox RG, Lamb RA, Williams JV, Crowe JE Jr, Jardetzky TS.

Nat Struct Mol Biol. 2012 Mar 4;19(4):461-3. doi: 10.1038/nsmb.2250.

49.

Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5.

Kim YH, Donald JE, Grigoryan G, Leser GP, Fadeev AY, Lamb RA, DeGrado WF.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):20992-7. doi: 10.1073/pnas.1116034108. Epub 2011 Dec 16.

50.

The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unit.

Zokarkar A, Lamb RA.

J Virol. 2012 Mar;86(5):2600-9. doi: 10.1128/JVI.06546-11. Epub 2011 Dec 14.

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