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Effects of Angle of Epiglottis on Aerodynamic and Acoustic Parameters in Excised Canine Larynges.

Zeng Q, Jiao Y, Huang X, Wang R, Bao H, Lamb JR, Le J, Zhuang P, Jiang J.

J Voice. 2019 Sep;33(5):627-633. doi: 10.1016/j.jvoice.2018.02.007. Epub 2018 Jun 28.


Visible-light-mediated, additive-free, and open-to-air controlled radical polymerization of acrylates and acrylamides.

Lamb JR, Qin KP, Johnson JA.

Polym Chem. 2019 Apr 7;10(13):1585-1590. doi: 10.1039/C9PY00022D. Epub 2019 Feb 8.


Measurement Reliability of Laryngeal Resistance and Mean Flow Rate in Pediatric Subjects.

Scholp AJ, Hedberg CD, Lamb JR, Hoffman MR, Braden MN, McMurray JS, Jiang JJ.

J Voice. 2019 Feb 19. pii: S0892-1997(18)30321-7. doi: 10.1016/j.jvoice.2019.02.005. [Epub ahead of print]


Regioselective Carbonylation of 2,2-Disubstituted Epoxides: An Alternative Route to Ketone-Based Aldol Products.

Hubbell AK, LaPointe AM, Lamb JR, Coates GW.

J Am Chem Soc. 2019 Feb 13;141(6):2474-2480. doi: 10.1021/jacs.8b12286. Epub 2019 Feb 1.


Measurement reliability of phonation threshold pressure in pediatric subjects.

Hoffman MR, Scholp AJ, Hedberg CD, Lamb JR, Braden MN, McMurray JS, Jiang JJ.

Laryngoscope. 2019 Jul;129(7):1520-1526. doi: 10.1002/lary.27418. Epub 2018 Nov 8.


Nucleophilic ring opening of trans-2,3-disubstituted epoxides to β-amino alcohols with catalyst-controlled regioselectivity.

Lee M, Lamb JR, Sanford MJ, LaPointe AM, Coates GW.

Chem Commun (Camb). 2018 Nov 15;54(92):12998-13001. doi: 10.1039/c8cc07200k.


The Role of Neonatal Gr-1+ Myeloid Cells in a Murine Model of Rhesus-Rotavirus-Induced Biliary Atresia.

Zhang R, Lin Z, Fu M, Guan X, Yu J, Zhong W, Zeng J, Lui VCH, Tam PKH, Lamb JR, Xia H, Chen Y.

Am J Pathol. 2018 Nov;188(11):2617-2628. doi: 10.1016/j.ajpath.2018.07.024. Epub 2018 Sep 8.


Downregulation of Hes1 expression in experimental biliary atresia and its effects on bile duct structure.

Zhang RZ, Zeng XH, Lin ZF, Ming-Fu, Tong YL, Lui VC, Tam PK, Lamb JR, Xia HM, Chen Y.

World J Gastroenterol. 2018 Aug 7;24(29):3260-3272. doi: 10.3748/wjg.v24.i29.3260.


Co-regulatory networks of human serum proteins link genetics to disease.

Emilsson V, Ilkov M, Lamb JR, Finkel N, Gudmundsson EF, Pitts R, Hoover H, Gudmundsdottir V, Horman SR, Aspelund T, Shu L, Trifonov V, Sigurdsson S, Manolescu A, Zhu J, Olafsson Ö, Jakobsdottir J, Lesley SA, To J, Zhang J, Harris TB, Launer LJ, Zhang B, Eiriksdottir G, Yang X, Orth AP, Jennings LL, Gudnason V.

Science. 2018 Aug 24;361(6404):769-773. doi: 10.1126/science.aaq1327. Epub 2018 Aug 2.


Silver nanoparticle treatment ameliorates biliary atresia syndrome in rhesus rotavirus inoculated mice.

Zhang R, Lin Z, Lui VCH, Wong KKY, Tam PKH, Lee P, Lok CN, Lamb JR, Chen Y, Xia H.

Nanomedicine. 2017 Apr;13(3):1041-1050. doi: 10.1016/j.nano.2016.11.013. Epub 2016 Nov 25.


Role of CD56-expressing immature biliary epithelial cells in biliary atresia.

Zhang RZ, Yu JK, Peng J, Wang FH, Liu HY, Lui VC, Nicholls JM, Tam PK, Lamb JR, Chen Y, Xia HM.

World J Gastroenterol. 2016 Feb 28;22(8):2545-57. doi: 10.3748/wjg.v22.i8.2545.


Mucosal inflammation at the respiratory interface: a zebrafish model.

Progatzky F, Cook HT, Lamb JR, Bugeon L, Dallman MJ.

Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15;310(6):L551-61. doi: 10.1152/ajplung.00323.2015. Epub 2015 Dec 30.


Regioselective Isomerization of 2,3-Disubstituted Epoxides to Ketones: An Alternative to the Wacker Oxidation of Internal Alkenes.

Lamb JR, Mulzer M, LaPointe AM, Coates GW.

J Am Chem Soc. 2015 Dec 2;137(47):15049-54. doi: 10.1021/jacs.5b10419. Epub 2015 Nov 20.


Modulatory effects of adiponectin on the polarization of tumor-associated macrophages.

Peng J, Tsang JY, Ho DH, Zhang R, Xiao H, Li D, Zhu J, Wang F, Bian Z, Lui VC, Xu A, Tam PK, Lamb JR, Xia H, Chen Y.

Int J Cancer. 2015 Aug 15;137(4):848-58. doi: 10.1002/ijc.29485. Epub 2015 Mar 4.


Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation.

Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR, Lamb JR, Bugeon L, Dallman MJ.

Nat Commun. 2014 Dec 23;5:5864. doi: 10.1038/ncomms6864.


Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.

Narayanan M, Huynh JL, Wang K, Yang X, Yoo S, McElwee J, Zhang B, Zhang C, Lamb JR, Xie T, Suver C, Molony C, Melquist S, Johnson AD, Fan G, Stone DJ, Schadt EE, Casaccia P, Emilsson V, Zhu J.

Mol Syst Biol. 2014 Jul 30;10:743. doi: 10.15252/msb.20145304.


Carbonylative enantioselective meso-desymmetrization of cis-epoxides to trans-β-lactones: effect of salen-ligand electronic variation on enantioselectivity.

Mulzer M, Lamb JR, Nelson Z, Coates GW.

Chem Commun (Camb). 2014 Sep 7;50(69):9842-5. doi: 10.1039/c4cc04397a.


Identification of altered dipeptidyl-peptidase activities as potential biomarkers for unipolar depression.

Deng J, Lamb JR, McKeown AP, Miller S, Muglia P, Guest PC, Bahn S, Domenici EH, Rahmoune H.

J Affect Disord. 2013 Nov;151(2):667-72. doi: 10.1016/j.jad.2013.07.015. Epub 2013 Jul 31.


Macrophage migration is controlled by Tribbles 1 through the interaction between C/EBPβ and TNF-α.

Liu YH, Tan KA, Morrison IW, Lamb JR, Argyle DJ.

Vet Immunol Immunopathol. 2013 Sep 1;155(1-2):67-75. doi: 10.1016/j.vetimm.2013.06.001. Epub 2013 Jun 6.


Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.

Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, MacDonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ, Gudnason V, Myers AJ, Schadt EE, Neumann H, Zhu J, Emilsson V.

Cell. 2013 Apr 25;153(3):707-20. doi: 10.1016/j.cell.2013.03.030.


Inhibition of TGF-β signaling in combination with TLR7 ligation re-programs a tumoricidal phenotype in tumor-associated macrophages.

Peng J, Tsang JY, Li D, Niu N, Ho DH, Lau KF, Lui VC, Lamb JR, Chen Y, Tam PK.

Cancer Lett. 2013 May 1;331(2):239-49. doi: 10.1016/j.canlet.2013.01.001. Epub 2013 Jan 11.


P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.

Taylor HB, Liepe J, Barthen C, Bugeon L, Huvet M, Kirk PD, Brown SB, Lamb JR, Stumpf MP, Dallman MJ.

Immunol Cell Biol. 2013 Jan;91(1):60-9. doi: 10.1038/icb.2012.57. Epub 2012 Nov 20.


Adiponectin mediated MHC class II mismatched cardiac graft rejection in mice is IL-4 dependent.

Li D, Tsang JY, Peng J, Ho DH, Chan YK, Zhu J, Lui VC, Xu A, Lamb JR, Tam PK, Chen Y.

PLoS One. 2012;7(11):e48893. doi: 10.1371/journal.pone.0048893. Epub 2012 Nov 14.


A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterations.

Xie T, D' Ario G, Lamb JR, Martin E, Wang K, Tejpar S, Delorenzi M, Bosman FT, Roth AD, Yan P, Bougel S, Di Narzo AF, Popovici V, Budinská E, Mao M, Weinrich SL, Rejto PA, Hodgson JG.

PLoS One. 2012;7(7):e42001. doi: 10.1371/journal.pone.0042001. Epub 2012 Jul 31.


The role of Nfil3 in zebrafish hematopoiesis.

Progatzky F, Taylor H, Bugeon L, Cassidy S, Radbruch A, Dallman MJ, Lamb JR.

Dev Comp Immunol. 2012 Sep;38(1):187-92. doi: 10.1016/j.dci.2012.04.008. Epub 2012 May 2.


Incorporation of an experimentally determined MTF for spatial frequency filtering and deconvolution during optical projection tomography reconstruction.

Chen L, McGinty J, Taylor HB, Bugeon L, Lamb JR, Dallman MJ, French PM.

Opt Express. 2012 Mar 26;20(7):7323-37. doi: 10.1364/OE.20.007323.


Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation.

Liepe J, Taylor H, Barnes CP, Huvet M, Bugeon L, Thorne T, Lamb JR, Dallman MJ, Stumpf MPH.

Integr Biol (Camb). 2012 Mar;4(3):335-345. doi: 10.1039/c2ib00175f. Epub 2012 Feb 10.


Effects of water uptake on melamine renal stone formation in mice.

Peng J, Li D, Chan YK, Chen Y, Lamb JR, Tam PK, El-Nezami H.

Nephrol Dial Transplant. 2012 Jun;27(6):2225-31. doi: 10.1093/ndt/gfr577. Epub 2011 Oct 10.


Novel synthesis of stable polypyrrole nanospheres using ozone.

Vetter CA, Suryawanshi A, Lamb JR, Law B, Gelling VJ.

Langmuir. 2011 Nov 15;27(22):13719-28. doi: 10.1021/la202947e. Epub 2011 Oct 12.


Inferring causal genomic alterations in breast cancer using gene expression data.

Tran LM, Zhang B, Zhang Z, Zhang C, Xie T, Lamb JR, Dai H, Schadt EE, Zhu J.

BMC Syst Biol. 2011 Aug 1;5:121. doi: 10.1186/1752-0509-5-121.


Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.

Lamb JR, Zhang C, Xie T, Wang K, Zhang B, Hao K, Chudin E, Fraser HB, Millstein J, Ferguson M, Suver C, Ivanovska I, Scott M, Philippar U, Bansal D, Zhang Z, Burchard J, Smith R, Greenawalt D, Cleary M, Derry J, Loboda A, Watters J, Poon RT, Fan ST, Yeung C, Lee NP, Guinney J, Molony C, Emilsson V, Buser-Doepner C, Zhu J, Friend S, Mao M, Shaw PM, Dai H, Luk JM, Schadt EE.

PLoS One. 2011;6(7):e20090. doi: 10.1371/journal.pone.0020090. Epub 2011 Jul 5.


In vivo fluorescence lifetime optical projection tomography.

McGinty J, Taylor HB, Chen L, Bugeon L, Lamb JR, Dallman MJ, French PM.

Biomed Opt Express. 2011 Apr 26;2(5):1340-50. doi: 10.1364/BOE.2.001340.


PPAR-γ signaling and IL-5 inhibition together prevent chronic rejection of MHC Class II-mismatched cardiac grafts.

Chen Y, Li D, Tsang JY, Niu N, Peng J, Zhu J, Hui K, Xu A, Lui VC, Lamb JR, Tam PK.

J Heart Lung Transplant. 2011 Jun;30(6):698-706. doi: 10.1016/j.healun.2011.01.704. Epub 2011 Mar 23.


Mast cells in health and disease.

Weller CL, Collington SJ, Williams T, Lamb JR.

Clin Sci (Lond). 2011 Jun;120(11):473-84. doi: 10.1042/CS20100459. Review.


Regulation of IL-17 in chronic inflammation in the human lung.

Pridgeon C, Bugeon L, Donnelly L, Straschil U, Tudhope SJ, Fenwick P, Lamb JR, Barnes PJ, Dallman MJ.

Clin Sci (Lond). 2011 Jun;120(12):515-24. doi: 10.1042/CS20100417.


microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma.

Burchard J, Zhang C, Liu AM, Poon RT, Lee NP, Wong KF, Sham PC, Lam BY, Ferguson MD, Tokiwa G, Smith R, Leeson B, Beard R, Lamb JR, Lim L, Mao M, Dai H, Luk JM.

Mol Syst Biol. 2010 Aug 24;6:402. doi: 10.1038/msb.2010.58.


Enhanced effector function of cytotoxic cells in the induced sputum of COPD patients.

Urbanowicz RA, Lamb JR, Todd I, Corne JM, Fairclough LC.

Respir Res. 2010 Jun 11;11:76. doi: 10.1186/1465-9921-11-76.


Complexity in common diseases: big biology for all.

Lamb JR, Gibson NW.

Sci Transl Med. 2010 Mar 31;2(25):25cm11. doi: 10.1126/scitranslmed.3000882.


Characterizing dynamic changes in the human blood transcriptional network.

Zhu J, Chen Y, Leonardson AS, Wang K, Lamb JR, Emilsson V, Schadt EE.

PLoS Comput Biol. 2010 Feb 12;6(2):e1000671. doi: 10.1371/journal.pcbi.1000671.


The effect of food intake on gene expression in human peripheral blood.

Leonardson AS, Zhu J, Chen Y, Wang K, Lamb JR, Reitman M, Emilsson V, Schadt EE.

Hum Mol Genet. 2010 Jan 1;19(1):159-69. doi: 10.1093/hmg/ddp476.


Altered effector function of peripheral cytotoxic cells in COPD.

Urbanowicz RA, Lamb JR, Todd I, Corne JM, Fairclough LC.

Respir Res. 2009 Jun 22;10:53. doi: 10.1186/1465-9921-10-53.


Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.

Yang X, Deignan JL, Qi H, Zhu J, Qian S, Zhong J, Torosyan G, Majid S, Falkard B, Kleinhanz RR, Karlsson J, Castellani LW, Mumick S, Wang K, Xie T, Coon M, Zhang C, Estrada-Smith D, Farber CR, Wang SS, van Nas A, Ghazalpour A, Zhang B, Macneil DJ, Lamb JR, Dipple KM, Reitman ML, Mehrabian M, Lum PY, Schadt EE, Lusis AJ, Drake TA.

Nat Genet. 2009 Apr;41(4):415-23. doi: 10.1038/ng.325. Epub 2009 Mar 8.


Human tribbles homologue 2 is expressed in unstable regions of carotid plaques and regulates macrophage IL-10 in vitro.

Deng J, James CH, Patel L, Smith A, Burnand KG, Rahmoune H, Lamb JR, Davis B.

Clin Sci (Lond). 2009 Feb;116(3):241-8. doi: 10.1042/CS20080058.


Genetics of gene expression and its effect on disease.

Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S, Mouy M, Steinthorsdottir V, Eiriksdottir GH, Bjornsdottir G, Reynisdottir I, Gudbjartsson D, Helgadottir A, Jonasdottir A, Jonasdottir A, Styrkarsdottir U, Gretarsdottir S, Magnusson KP, Stefansson H, Fossdal R, Kristjansson K, Gislason HG, Stefansson T, Leifsson BG, Thorsteinsdottir U, Lamb JR, Gulcher JR, Reitman ML, Kong A, Schadt EE, Stefansson K.

Nature. 2008 Mar 27;452(7186):423-8. doi: 10.1038/nature06758. Epub 2008 Mar 16.


Killer cells in chronic obstructive pulmonary disease.

Fairclough L, Urbanowicz RA, Corne J, Lamb JR.

Clin Sci (Lond). 2008 Apr;114(8):533-41. doi: 10.1042/CS20070356. Review.


Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation.

Liu Y, Chen Y, Liu FQ, Lamb JR, Tam PK.

Transpl Int. 2008 May;21(5):483-94. doi: 10.1111/j.1432-2277.2007.00630.x. Epub 2008 Feb 4.


Hypoxia modulates lipopolysaccharide induced TNF-alpha expression in murine macrophages.

Liu FQ, Liu Y, Lui VC, Lamb JR, Tam PK, Chen Y.

Exp Cell Res. 2008 Apr 1;314(6):1327-36. doi: 10.1016/j.yexcr.2008.01.007. Epub 2008 Jan 16.


LPS-induced up-regulation of TGF-beta receptor 1 is associated with TNF-alpha expression in human monocyte-derived macrophages.

Chen Y, Kam CS, Liu FQ, Liu Y, Lui VC, Lamb JR, Tam PK.

J Leukoc Biol. 2008 May;83(5):1165-73. doi: 10.1189/jlb.0807521. Epub 2008 Feb 5.


Triptolide, a component of Chinese herbal medicine, modulates the functional phenotype of dendritic cells.

Liu Y, Chen Y, Lamb JR, Tam PK.

Transplantation. 2007 Dec 15;84(11):1517-26.


Interleukin-10 is upregulated by nanomolar rosiglitazone treatment of mature dendritic cells and human CD4+ T cells.

Thompson PW, Bayliffe AI, Warren AP, Lamb JR.

Cytokine. 2007 Sep;39(3):184-91. Epub 2007 Sep 5.


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