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Items: 1 to 50 of 321

1.

Correction: DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract.

Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Al-Gazali L, Shamsi AMSMA, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR.

Genet Med. 2019 Dec 20. doi: 10.1038/s41436-019-0732-6. [Epub ahead of print]

PMID:
31857706
2.

An approach that someday may boost testosterone biosynthesis in males with late-onset hypogonadism (low testosterone).

Lamb DJ.

Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):22904-22906. doi: 10.1073/pnas.1916719116. Epub 2019 Oct 25. No abstract available.

3.

Differential modulation of transendothelial electrical resistance by TRPV4 agonists is mediated by apoptosis and/or necrosis.

Pairet N, Mang S, Kiechle T, Laufhäger N, Dietl P, Lamb DJ.

Biochem Biophys Rep. 2019 Sep 19;20:100672. doi: 10.1016/j.bbrep.2019.100672. eCollection 2019 Dec.

4.

Characterization of the renal phenotype in RMND1-related mitochondrial disease.

Shayota BJ, Le NT, Bekheirnia N, Rosenfeld JA, Goldstein AC, Moritz M, Bartholomew DW, Pastore MT, Xia F, Eng C, Yang Y, Lamb DJ, Scaglia F, Braun MC, Bekheirnia MR.

Mol Genet Genomic Med. 2019 Dec;7(12):e973. doi: 10.1002/mgg3.973. Epub 2019 Sep 30.

5.

DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract.

Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Al-Gazali L, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR.

Genet Med. 2019 Dec;21(12):2755-2764. doi: 10.1038/s41436-019-0576-0. Epub 2019 Jul 2. Erratum in: Genet Med. 2019 Dec 20;:.

6.

Where are we going with gene screening for male infertility?

Thirumavalavan N, Gabrielsen JS, Lamb DJ.

Fertil Steril. 2019 May;111(5):842-850. doi: 10.1016/j.fertnstert.2019.03.036. Review.

PMID:
31029238
7.

Distribution of Semen Parameters Among Adolescent Males Undergoing Fertility Preservation in a Multicenter International Cohort.

Halpern JA, Thirumavalavan N, Kohn TP, Patel AS, Leong JY, Cervellione RM, Keene DJB, Ibrahim E, Brackett NL, Lamb DJ, Ramasamy R.

Urology. 2019 May;127:119-123. doi: 10.1016/j.urology.2019.01.027. Epub 2019 Feb 13.

PMID:
30771377
8.

The risk of birth defects is not associated with semen parameters or mode of conception in offspring of men visiting a reproductive health clinic.

Pastuszak AW, Herati AS, Eisenberg ML, Cengiz C, Langlois PH, Kohn TP, Lamb DJ, Lipshultz LI.

Hum Reprod. 2019 Apr 1;34(4):733-739. doi: 10.1093/humrep/dez005.

PMID:
30753581
9.

Does Solid Organ Transplantation Affect Male Reproduction?

Thirumavalavan N, Scovell JM, Link RE, Lamb DJ, Lipshultz LI.

Eur Urol Focus. 2018 Apr;4(3):307-310. doi: 10.1016/j.euf.2018.08.012. Epub 2018 Sep 5. Review.

10.

Role of Sperm Morphology in Deciding Between Various Assisted Reproduction Technologies.

Kohn TP, Kohn JR, Lamb DJ.

Eur Urol Focus. 2018 Apr;4(3):311-313. doi: 10.1016/j.euf.2018.07.029. Epub 2018 Aug 22. Review.

PMID:
30143470
11.

Iron and a Man's Reproductive Health: the Good, the Bad, and the Ugly.

Gabrielsen JS, Lamb DJ, Lipshultz LI.

Curr Urol Rep. 2018 Jun 1;19(8):60. doi: 10.1007/s11934-018-0808-x. Review.

12.

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation.

Pairet N, Mang S, Fois G, Keck M, Kühnbach M, Gindele J, Frick M, Dietl P, Lamb DJ.

PLoS One. 2018 Apr 17;13(4):e0196055. doi: 10.1371/journal.pone.0196055. eCollection 2018.

13.

Importance of the IL-1 Axis in Haemophilus influenzae-stimulated M1 Macrophages Driving Transepithelial Signaling.

Mang S, Braun A, Pairet N, Lamb DJ.

Am J Respir Cell Mol Biol. 2018 Mar;58(3):412-415. doi: 10.1165/rcmb.2017-0283LE. No abstract available.

PMID:
29493324
14.

16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development.

Haller M, Au J, O'Neill M, Lamb DJ.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1849-E1858. doi: 10.1073/pnas.1716092115. Epub 2018 Feb 5.

15.

Novel Application of Micro-Computerized Tomography for Morphologic Characterization of the Murine Penis.

O'Neill M, Huang GO, Lamb DJ.

J Sex Med. 2017 Dec;14(12):1533-1539. doi: 10.1016/j.jsxm.2017.10.065. Epub 2017 Nov 16.

16.

Frontiers in sperm function testing: DNA fragmentation analysis shows promise.

Herati AS, Lamb DJ.

Transl Androl Urol. 2017 Sep;6(Suppl 4):S457-S458. doi: 10.21037/tau.2017.03.76. No abstract available.

17.

The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities.

Barratt CLR, Björndahl L, De Jonge CJ, Lamb DJ, Osorio Martini F, McLachlan R, Oates RD, van der Poel S, St John B, Sigman M, Sokol R, Tournaye H.

Hum Reprod Update. 2017 Nov 1;23(6):660-680. doi: 10.1093/humupd/dmx021. Review.

18.

Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing.

Gindele JA, Mang S, Pairet N, Christ I, Gantner F, Schymeinsky J, Lamb DJ.

PLoS One. 2017 Sep 1;12(9):e0184386. doi: 10.1371/journal.pone.0184386. eCollection 2017.

19.

Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development.

Haller M, Mo Q, Imamoto A, Lamb DJ.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):4981-4986. doi: 10.1073/pnas.1619523114. Epub 2017 Apr 24.

20.

Neutralization of both IL-1α/IL-1β plays a major role in suppressing combined cigarette smoke/virus-induced pulmonary inflammation in mice.

Bucher H, Mang S, Keck M, Przibilla M, Lamb DJ, Schiele F, Wittenbrink M, Fuchs K, Jung B, Erb KJ, Peter D.

Pulm Pharmacol Ther. 2017 Jun;44:96-105. doi: 10.1016/j.pupt.2017.03.008. Epub 2017 Mar 15.

21.

Age-related alterations in the genetics and genomics of the male germ line.

Herati AS, Zhelyazkova BH, Butler PR, Lamb DJ.

Fertil Steril. 2017 Feb;107(2):319-323. doi: 10.1016/j.fertnstert.2016.12.021. Review.

PMID:
28160920
22.

Poor Sleep Quality Predicts Hypogonadal Symptoms and Sexual Dysfunction in Male Nonstandard Shift Workers.

Pastuszak AW, Moon YM, Scovell J, Badal J, Lamb DJ, Link RE, Lipshultz LI.

Urology. 2017 Apr;102:121-125. doi: 10.1016/j.urology.2016.11.033. Epub 2016 Dec 14.

23.

Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.

Tabeling C, Herbert J, Hocke AC, Lamb DJ, Wollin SL, Erb KJ, Boiarina E, Movassagh H, Scheffel J, Doehn JM, Hippenstiel S, Maurer M, Gounni AS, Kuebler WM, Suttorp N, Witzenrath M.

Allergy. 2017 Jul;72(7):1061-1072. doi: 10.1111/all.13101. Epub 2017 Jan 12.

PMID:
27906453
24.

Men with a complete absence of normal sperm morphology exhibit high rates of success without assisted reproduction.

Kovac JR, Smith RP, Cajipe M, Lamb DJ, Lipshultz LI.

Asian J Androl. 2017 Jan-Feb;19(1):39-42. doi: 10.4103/1008-682X.189211.

25.

Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene.

Bekheirnia MR, Bekheirnia N, Bainbridge MN, Gu S, Coban Akdemir ZH, Gambin T, Janzen NK, Jhangiani SN, Muzny DM, Michael M, Brewer ED, Elenberg E, Kale AS, Riley AA, Swartz SJ, Scott DA, Yang Y, Srivaths PR, Wenderfer SE, Bodurtha J, Applegate CD, Velinov M, Myers A, Borovik L, Craigen WJ, Hanchard NA, Rosenfeld JA, Lewis RA, Gonzales ET, Gibbs RA, Belmont JW, Roth DR, Eng C, Braun MC, Lupski JR, Lamb DJ.

Genet Med. 2017 Apr;19(4):412-420. doi: 10.1038/gim.2016.131. Epub 2016 Sep 22.

26.

Assays of Serum Testosterone.

Herati AS, Cengiz C, Lamb DJ.

Urol Clin North Am. 2016 May;43(2):177-84. doi: 10.1016/j.ucl.2016.01.003. Review.

PMID:
27132574
27.

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction.

van Eeuwijk JM, Stegner D, Lamb DJ, Kraft P, Beck S, Thielmann I, Kiefer F, Walzog B, Stoll G, Nieswandt B.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1247-53. doi: 10.1161/ATVBAHA.115.306883. Epub 2016 Apr 21.

PMID:
27102960
28.

Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway.

Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K.

PLoS One. 2016 Apr 15;11(4):e0153968. doi: 10.1371/journal.pone.0153968. eCollection 2016.

29.

Recent advances in the genetics of testicular failure.

Song SH, Chiba K, Ramasamy R, Lamb DJ.

Asian J Androl. 2016 May-Jun;18(3):350-5. doi: 10.4103/1008-682X.178857. Review.

30.

BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.

Lamb DJ, Wollin SL, Schnapp A, Bischoff D, Erb KJ, Bouyssou T, Guilliard B, Strasser C, Wex E, Blum S, Thaler E, Nickel H, Radmacher O, Haas H, Swantek JL, Souza D, Canfield M, White D, Panzenbeck M, Kashem MA, Sanville-Ross M, Kono T, Sewald K, Braun A, Obernolte H, Danov O, Schaenzle G, Rast G, Maier GM, Hoffmann M.

J Pharmacol Exp Ther. 2016 Jun;357(3):554-61. doi: 10.1124/jpet.116.233155. Epub 2016 Apr 5.

PMID:
27048659
31.

Ghrelin ameliorates adhesions in a postsurgical mouse model.

Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K.

J Surg Res. 2016 Mar;201(1):226-34. doi: 10.1016/j.jss.2015.10.044. Epub 2015 Nov 5.

32.

Comprehensive Assessment of Health Needs of Young Minority Males Attending a Family Planning Clinic.

Pastuszak AW, Wenker EP, Smith PB, Abacan A, Lamb DJ, Lipshultz LI, Buzi R.

Am J Mens Health. 2017 May;11(3):542-551. doi: 10.1177/1557988316629627. Epub 2016 Feb 4.

33.

The varicocele: diagnostic dilemmas, therapeutic challenges and future perspectives.

Chiba K, Ramasamy R, Lamb DJ, Lipshultz LI.

Asian J Androl. 2016 Mar-Apr;18(2):276-81. doi: 10.4103/1008-682X.167724. Review.

34.

Comparison of the Effects of Testosterone Gels, Injections, and Pellets on Serum Hormones, Erythrocytosis, Lipids, and Prostate-Specific Antigen.

Pastuszak AW, Gomez LP, Scovell JM, Khera M, Lamb DJ, Lipshultz LI.

Sex Med. 2015 Sep;3(3):165-73. doi: 10.1002/sm2.76. Epub 2015 Aug 12.

35.

Reproductive outcomes in men with karyotype abnormalities: Case report and review of the literature.

Kohn TP, Clavijo R, Ramasamy R, Hakky T, Candrashekar A, Lamb DJ, Lipshultz LI.

Can Urol Assoc J. 2015 Sep-Oct;9(9-10):E667-70. doi: 10.5489/cuaj.2902. Epub 2015 Sep 9.

36.

Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice.

Garcia JM, Chen JA, Guillory B, Donehower LA, Smith RG, Lamb DJ.

Biol Reprod. 2015 Jul;93(1):24. doi: 10.1095/biolreprod.115.129759. Epub 2015 May 27.

37.

Whole-exome sequencing identifies novel homozygous mutation in NPAS2 in family with nonobstructive azoospermia.

Ramasamy R, Bakırcıoğlu ME, Cengiz C, Karaca E, Scovell J, Jhangiani SN, Akdemir ZC, Bainbridge M, Yu Y, Huff C, Gibbs RA, Lupski JR, Lamb DJ.

Fertil Steril. 2015 Aug;104(2):286-91. doi: 10.1016/j.fertnstert.2015.04.001. Epub 2015 May 5.

38.

The need to improve patient care through discriminate use of intracytoplasmic sperm injection (ICSI) and improved understanding of spermatozoa, oocyte and embryo biology.

Carrell DT, Nyboe Andersen A, Lamb DJ.

Andrology. 2015 Mar;3(2):143-6. doi: 10.1111/andr.12034. No abstract available.

39.

Male biological clock: a critical analysis of advanced paternal age.

Ramasamy R, Chiba K, Butler P, Lamb DJ.

Fertil Steril. 2015 Jun;103(6):1402-6. doi: 10.1016/j.fertnstert.2015.03.011. Epub 2015 Apr 14. Review.

40.

Words of wisdom. Re: Testosterone treatment is a potent tumor promoter for the rat prostate.

Scovell JM, Butler P, Ramasamy R, Lamb DJ.

Eur Urol. 2015 Apr;67(4):814-5. doi: 10.1016/j.eururo.2014.12.049. No abstract available.

41.

Fluorescence in situ hybridization detects increased sperm aneuploidy in men with recurrent pregnancy loss.

Ramasamy R, Scovell JM, Kovac JR, Cook PJ, Lamb DJ, Lipshultz LI.

Fertil Steril. 2015 Apr;103(4):906-909.e1. doi: 10.1016/j.fertnstert.2015.01.029. Epub 2015 Feb 20.

42.

Ghrelin partially protects against cisplatin-induced male murine gonadal toxicity in a GHSR-1a-dependent manner.

Whirledge SD, Garcia JM, Smith RG, Lamb DJ.

Biol Reprod. 2015 Mar;92(3):76. doi: 10.1095/biolreprod.114.123570. Epub 2015 Jan 28.

43.

CYP17A1 inhibitors in castration-resistant prostate cancer.

Gomez L, Kovac JR, Lamb DJ.

Steroids. 2015 Mar;95:80-7. doi: 10.1016/j.steroids.2014.12.021. Epub 2015 Jan 3. Review.

44.

Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia.

Jorgez CJ, Wilken N, Addai JB, Newberg J, Vangapandu HV, Pastuszak AW, Mukherjee S, Rosenfeld JA, Lipshultz LI, Lamb DJ.

Fertil Steril. 2015 Jan;103(1):44-52.e1. doi: 10.1016/j.fertnstert.2014.09.021. Epub 2014 Oct 24.

45.

Fluorescent in situ hybridization of human sperm: diagnostics, indications, and therapeutic implications.

Ramasamy R, Besada S, Lamb DJ.

Fertil Steril. 2014 Dec;102(6):1534-9. doi: 10.1016/j.fertnstert.2014.09.013. Epub 2014 Oct 22.

46.

Testosterone supplementation therapy in the treatment of patients with metabolic syndrome.

Kovac JR, Pastuszak AW, Lamb DJ, Lipshultz LI.

Postgrad Med. 2014 Nov;126(7):149-56. doi: 10.3810/pgm.2014.11.2843. Review. Erratum in: Postgrad Med. 2015 Jan;127(1):117. Kovac, Jason [corrected to Kovac, Jason R].

47.

Genitourinary defects associated with genomic deletions in 2p15 encompassing OTX1.

Jorgez CJ, Rosenfeld JA, Wilken NR, Vangapandu HV, Sahin A, Pham D, Carvalho CM, Bandholz A, Miller A, Weaver DD, Burton B, Babu D, Bamforth JS, Wilks T, Flynn DP, Roeder E, Patel A, Cheung SW, Lupski JR, Lamb DJ.

PLoS One. 2014 Sep 9;9(9):e107028. doi: 10.1371/journal.pone.0107028. eCollection 2014.

48.

Testosterone therapy and mortality risk.

Eisenberg ML, Li S, Herder D, Lamb DJ, Lipshultz LI.

Int J Impot Res. 2015 Mar-Apr;27(2):46-8. doi: 10.1038/ijir.2014.29. Epub 2014 Jul 31.

49.

Current state of practice regarding testosterone supplementation therapy in men with prostate cancer.

Kovac JR, Pan MM, Lipshultz LI, Lamb DJ.

Steroids. 2014 Nov;89:27-32. doi: 10.1016/j.steroids.2014.07.004. Epub 2014 Jul 27. Review.

50.

Integrative DNA methylation and gene expression analysis identifies discoidin domain receptor 1 association with idiopathic nonobstructive azoospermia.

Ramasamy R, Ridgeway A, Lipshultz LI, Lamb DJ.

Fertil Steril. 2014 Oct;102(4):968-973.e3. doi: 10.1016/j.fertnstert.2014.06.028. Epub 2014 Jul 23.

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