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Items: 1 to 50 of 189

1.

Actin stabilizing compounds show specific biological effects due to their binding mode.

Wang S, Crevenna AH, Ugur I, Marion A, Antes I, Kazmaier U, Hoyer M, Lamb DC, Gegenfurtner F, Kliesmete Z, Ziegenhain C, Enard W, Vollmar A, Zahler S.

Sci Rep. 2019 Jul 5;9(1):9731. doi: 10.1038/s41598-019-46282-w.

2.

Nanoresolution real-time 3D orbital tracking for studying mitochondrial trafficking in vertebrate axons in vivo.

Wehnekamp F, Plucińska G, Thong R, Misgeld T, Lamb DC.

Elife. 2019 Jun 10;8. pii: e46059. doi: 10.7554/eLife.46059.

3.

On the occurrence of cytochrome P450 in viruses.

Lamb DC, Follmer AH, Goldstone JV, Nelson DR, Warrilow AG, Price CL, True MY, Kelly SL, Poulos TL, Stegeman JJ.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12343-12352. doi: 10.1073/pnas.1901080116. Epub 2019 Jun 5.

PMID:
31167942
4.

Tuning porosity in macroscopic monolithic metal-organic frameworks for exceptional natural gas storage.

Connolly BM, Aragones-Anglada M, Gandara-Loe J, Danaf NA, Lamb DC, Mehta JP, Vulpe D, Wuttke S, Silvestre-Albero J, Moghadam PZ, Wheatley AEH, Fairen-Jimenez D.

Nat Commun. 2019 May 28;10(1):2345. doi: 10.1038/s41467-019-10185-1.

5.

Quantitative Single-Molecule Three-Color Förster Resonance Energy Transfer by Photon Distribution Analysis.

Barth A, Voith von Voithenberg L, Lamb DC.

J Phys Chem B. 2019 Aug 15;123(32):6901-6916. doi: 10.1021/acs.jpcb.9b02967. Epub 2019 Jun 4.

PMID:
31117611
6.

Coordinated Conformational Processing of the Tumor Suppressor Protein p53 by the Hsp70 and Hsp90 Chaperone Machineries.

Dahiya V, Agam G, Lawatscheck J, Rutz DA, Lamb DC, Buchner J.

Mol Cell. 2019 May 16;74(4):816-830.e7. doi: 10.1016/j.molcel.2019.03.026. Epub 2019 Apr 23.

PMID:
31027879
7.

Coordinative Binding of Polymers to Metal-Organic Framework Nanoparticles for Control of Interactions at the Biointerface.

Zimpel A, Al Danaf N, Steinborn B, Kuhn J, Höhn M, Bauer T, Hirschle P, Schrimpf W, Engelke H, Wagner E, Barz M, Lamb DC, Lächelt U, Wuttke S.

ACS Nano. 2019 Apr 23;13(4):3884-3895. doi: 10.1021/acsnano.8b06287. Epub 2019 Mar 15.

PMID:
30844241
8.

Density fluctuations as door-opener for diffusion on crowded surfaces.

Henß AK, Sakong S, Messer PK, Wiechers J, Schuster R, Lamb DC, Groß A, Wintterlin J.

Science. 2019 Feb 15;363(6428):715-718. doi: 10.1126/science.aav4143. Epub 2019 Feb 14.

PMID:
30765561
9.

Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP-DNA dissociation.

Heiss G, Ploetz E, Voith von Voithenberg L, Viswanathan R, Glaser S, Schluesche P, Madhira S, Meisterernst M, Auble DT, Lamb DC.

Nucleic Acids Res. 2019 Apr 8;47(6):2793-2806. doi: 10.1093/nar/gky1322.

10.

Analyzing the Dynamics of Single TBP-DNA-NC2 Complexes Using Hidden Markov Models.

Zarrabi N, Schluesche P, Meisterernst M, Börsch M, Lamb DC.

Biophys J. 2018 Dec 18;115(12):2310-2326. doi: 10.1016/j.bpj.2018.11.015. Epub 2018 Nov 17.

PMID:
30527334
11.

Dynamic interactions of type I cohesin modules fine-tune the structure of the cellulosome of Clostridium thermocellum.

Barth A, Hendrix J, Fried D, Barak Y, Bayer EA, Lamb DC.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11274-E11283. doi: 10.1073/pnas.1809283115. Epub 2018 Nov 14.

12.

Publisher Correction: Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study.

Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Adariani SR, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, Gebhardt C, Götz M, Gouridis G, Gratton E, Ha T, Hao P, Hanke CA, Hartmann A, Hendrix J, Hildebrandt LL, Hirschfeld V, Hohlbein J, Hua B, Hübner CG, Kallis E, Kapanidis AN, Kim JY, Krainer G, Lamb DC, Lee NK, Lemke EA, Levesque B, Levitus M, McCann JJ, Naredi-Rainer N, Nettels D, Ngo T, Qiu R, Robb NC, Röcker C, Sanabria H, Schlierf M, Schröder T, Schuler B, Seidel H, Streit L, Thurn J, Tinnefeld P, Tyagi S, Vandenberk N, Vera AM, Weninger KR, Wünsch B, Yanez-Orozco IS, Michaelis J, Seidel CAM, Craggs TD, Hugel T.

Nat Methods. 2018 Nov;15(11):984. doi: 10.1038/s41592-018-0193-x.

PMID:
30327572
13.

Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone.

Gegenfurtner FA, Zisis T, Al Danaf N, Schrimpf W, Kliesmete Z, Ziegenhain C, Enard W, Kazmaier U, Lamb DC, Vollmar AM, Zahler S.

Cell Mol Life Sci. 2018 Dec;75(24):4539-4555. doi: 10.1007/s00018-018-2919-4. Epub 2018 Sep 11.

PMID:
30206640
14.

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study.

Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Rezaei Adariani S, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, Gebhardt C, Götz M, Gouridis G, Gratton E, Ha T, Hao P, Hanke CA, Hartmann A, Hendrix J, Hildebrandt LL, Hirschfeld V, Hohlbein J, Hua B, Hübner CG, Kallis E, Kapanidis AN, Kim JY, Krainer G, Lamb DC, Lee NK, Lemke EA, Levesque B, Levitus M, McCann JJ, Naredi-Rainer N, Nettels D, Ngo T, Qiu R, Robb NC, Röcker C, Sanabria H, Schlierf M, Schröder T, Schuler B, Seidel H, Streit L, Thurn J, Tinnefeld P, Tyagi S, Vandenberk N, Vera AM, Weninger KR, Wünsch B, Yanez-Orozco IS, Michaelis J, Seidel CAM, Craggs TD, Hugel T.

Nat Methods. 2018 Sep;15(9):669-676. doi: 10.1038/s41592-018-0085-0. Epub 2018 Aug 31. Erratum in: Nat Methods. 2018 Nov;15(11):984.

15.

Stability of local secondary structure determines selectivity of viral RNA chaperones.

Bravo JPK, Borodavka A, Barth A, Calabrese AN, Mojzes P, Cockburn JJB, Lamb DC, Tuma R.

Nucleic Acids Res. 2018 Sep 6;46(15):7924-7937. doi: 10.1093/nar/gky394.

16.

Chemical diversity in a metal-organic framework revealed by fluorescence lifetime imaging.

Schrimpf W, Jiang J, Ji Z, Hirschle P, Lamb DC, Yaghi OM, Wuttke S.

Nat Commun. 2018 Apr 25;9(1):1647. doi: 10.1038/s41467-018-04050-w.

17.

PAM: A Framework for Integrated Analysis of Imaging, Single-Molecule, and Ensemble Fluorescence Data.

Schrimpf W, Barth A, Hendrix J, Lamb DC.

Biophys J. 2018 Apr 10;114(7):1518-1528. doi: 10.1016/j.bpj.2018.02.035.

18.

Crosstalk-free multicolor RICS using spectral weighting.

Schrimpf W, Lemmens V, Smisdom N, Ameloot M, Lamb DC, Hendrix J.

Methods. 2018 May 1;140-141:97-111. doi: 10.1016/j.ymeth.2018.01.022. Epub 2018 Feb 22.

PMID:
29408283
19.

A self-assembled nanoscale robotic arm controlled by electric fields.

Kopperger E, List J, Madhira S, Rothfischer F, Lamb DC, Simmel FC.

Science. 2018 Jan 19;359(6373):296-301. doi: 10.1126/science.aao4284.

PMID:
29348232
20.

Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate.

Rosam M, Krader D, Nickels C, Hochmair J, Back KC, Agam G, Barth A, Zeymer C, Hendrix J, Schneider M, Antes I, Reinstein J, Lamb DC, Buchner J.

Nat Struct Mol Biol. 2018 Jan;25(1):90-100. doi: 10.1038/s41594-017-0012-6. Epub 2018 Jan 1.

PMID:
29323281
21.

Single Pair Förster Resonance Energy Transfer: A Versatile Tool To Investigate Protein Conformational Dynamics.

Voith von Voithenberg L, Lamb DC.

Bioessays. 2018 Mar;40(3). doi: 10.1002/bies.201700078. Epub 2018 Jan 5. Review.

PMID:
29314107
22.

Directional Photonic Wire Mediated by Homo-Förster Resonance Energy Transfer on a DNA Origami Platform.

Nicoli F, Barth A, Bae W, Neukirchinger F, Crevenna AH, Lamb DC, Liedl T.

ACS Nano. 2017 Nov 28;11(11):11264-11272. doi: 10.1021/acsnano.7b05631. Epub 2017 Nov 1.

23.

Protein-mediated RNA folding governs sequence-specific interactions between rotavirus genome segments.

Borodavka A, Dykeman EC, Schrimpf W, Lamb DC.

Elife. 2017 Sep 18;6. pii: e27453. doi: 10.7554/eLife.27453.

24.

Effects of Fluorophore Attachment on Protein Conformation and Dynamics Studied by spFRET and NMR Spectroscopy.

Sánchez-Rico C, Voith von Voithenberg L, Warner L, Lamb DC, Sattler M.

Chemistry. 2017 Oct 12;23(57):14267-14277. doi: 10.1002/chem.201702423. Epub 2017 Sep 12.

25.

Inhibition of the V-ATPase by Archazolid A: A New Strategy to Inhibit EMT.

Merk H, Messer P, Ardelt MA, Lamb DC, Zahler S, Müller R, Vollmar AM, Pachmayr J.

Mol Cancer Ther. 2017 Nov;16(11):2329-2339. doi: 10.1158/1535-7163.MCT-17-0129. Epub 2017 Aug 3.

26.

Molecular adaptation to high pressure in cytochrome P450 1A and aryl hydrocarbon receptor systems of the deep-sea fish Coryphaenoides armatus.

Lemaire B, Karchner SI, Goldstone JV, Lamb DC, Drazen JC, Rees JF, Hahn ME, Stegeman JJ.

Biochim Biophys Acta Proteins Proteom. 2018 Jan;1866(1):155-165. doi: 10.1016/j.bbapap.2017.06.026. Epub 2017 Jul 8.

27.

Covalent dye attachment influences the dynamics and conformational properties of flexible peptides.

Luitz MP, Barth A, Crevenna AH, Bomblies R, Lamb DC, Zacharias M.

PLoS One. 2017 May 23;12(5):e0177139. doi: 10.1371/journal.pone.0177139. eCollection 2017.

28.

3D motion of vesicles along microtubules helps them to circumvent obstacles in cells.

Verdeny-Vilanova I, Wehnekamp F, Mohan N, Sandoval Álvarez Á, Borbely JS, Otterstrom JJ, Lamb DC, Lakadamyali M.

J Cell Sci. 2017 Jun 1;130(11):1904-1916. doi: 10.1242/jcs.201178. Epub 2017 Apr 18.

29.

Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods.

Heissig P, Schrimpf W, Hadwiger P, Wagner E, Lamb DC.

PLoS One. 2017 Mar 9;12(3):e0173401. doi: 10.1371/journal.pone.0173401. eCollection 2017.

30.

Structural Dynamics of the YidC:Ribosome Complex during Membrane Protein Biogenesis.

Kedrov A, Wickles S, Crevenna AH, van der Sluis EO, Buschauer R, Berninghausen O, Lamb DC, Beckmann R.

Cell Rep. 2016 Dec 13;17(11):2943-2954. doi: 10.1016/j.celrep.2016.11.059.

31.

The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.

Galilee M, Britan-Rosich E, Griner SL, Uysal S, Baumgärtel V, Lamb DC, Kossiakoff AA, Kotler M, Stroud RM, Marx A, Alian A.

Structure. 2016 Nov 1;24(11):1936-1946. doi: 10.1016/j.str.2016.08.015. Epub 2016 Sep 29.

32.

Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift.

Voith von Voithenberg L, Sánchez-Rico C, Kang HS, Madl T, Zanier K, Barth A, Warner LR, Sattler M, Lamb DC.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7169-E7175. Epub 2016 Oct 31.

33.

Arbitrary-Region Raster Image Correlation Spectroscopy.

Hendrix J, Dekens T, Schrimpf W, Lamb DC.

Biophys J. 2016 Oct 18;111(8):1785-1796. doi: 10.1016/j.bpj.2016.09.012.

34.

Investigation of the Co-Dependence of Morphology and Fluorescence Lifetime in a Metal-Organic Framework.

Schrimpf W, Ossato G, Hirschle P, Wuttke S, Lamb DC.

Small. 2016 Jul;12(27):3651-7. doi: 10.1002/smll.201600619. Epub 2016 May 12.

PMID:
27171620
35.

Secretory cargo sorting by Ca2+-dependent Cab45 oligomerization at the trans-Golgi network.

Crevenna AH, Blank B, Maiser A, Emin D, Prescher J, Beck G, Kienzle C, Bartnik K, Habermann B, Pakdel M, Leonhardt H, Lamb DC, von Blume J.

J Cell Biol. 2016 May 9;213(3):305-14. doi: 10.1083/jcb.201601089. Epub 2016 May 2.

36.

Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders.

Lemaire B, Kubota A, O'Meara CM, Lamb DC, Tanguay RL, Goldstone JV, Stegeman JJ.

Toxicol Appl Pharmacol. 2016 Apr 1;296:73-84. doi: 10.1016/j.taap.2016.02.001. Epub 2016 Feb 4.

37.

Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.

Lee DJ, Kessel E, Edinger D, He D, Klein PM, Voith von Voithenberg L, Lamb DC, Lächelt U, Lehto T, Wagner E.

Biomaterials. 2016 Jan;77:98-110. doi: 10.1016/j.biomaterials.2015.11.004. Epub 2015 Nov 5.

PMID:
26584350
38.

Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.

Goldstone JV, Sundaramoorthy M, Zhao B, Waterman MR, Stegeman JJ, Lamb DC.

Mol Phylogenet Evol. 2016 Jan;94(Pt B):676-687. doi: 10.1016/j.ympev.2015.09.012. Epub 2015 Oct 3.

39.

Live-cell observation of cytosolic HIV-1 assembly onset reveals RNA-interacting Gag oligomers.

Hendrix J, Baumgärtel V, Schrimpf W, Ivanchenko S, Digman MA, Gratton E, Kräusslich HG, Müller B, Lamb DC.

J Cell Biol. 2015 Aug 17;210(4):629-46. doi: 10.1083/jcb.201504006.

40.

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs.

Hargrove TY, Wawrzak Z, Lamb DC, Guengerich FP, Lepesheva GI.

J Biol Chem. 2015 Sep 25;290(39):23916-34. doi: 10.1074/jbc.M115.677310. Epub 2015 Aug 12.

41.

Role of the Cytosolic Loop C2 and the C Terminus of YidC in Ribosome Binding and Insertion Activity.

Geng Y, Kedrov A, Caumanns JJ, Crevenna AH, Lamb DC, Beckmann R, Driessen AJ.

J Biol Chem. 2015 Jul 10;290(28):17250-61. doi: 10.1074/jbc.M115.650309. Epub 2015 May 28.

42.

Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51).

Lamb DC, Warrilow AG, Rolley NJ, Parker JE, Nes WD, Smith SN, Kelly DE, Kelly SL.

Antimicrob Agents Chemother. 2015 Aug;59(8):4707-13. doi: 10.1128/AAC.00476-15. Epub 2015 May 26.

43.

Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules.

Röhl A, Wengler D, Madl T, Lagleder S, Tippel F, Herrmann M, Hendrix J, Richter K, Hack G, Schmid AB, Kessler H, Lamb DC, Buchner J.

Nat Commun. 2015 Apr 8;6:6655. doi: 10.1038/ncomms7655.

44.

Super-resolution imaging of ESCRT-proteins at HIV-1 assembly sites.

Prescher J, Baumgärtel V, Ivanchenko S, Torrano AA, Bräuchle C, Müller B, Lamb DC.

PLoS Pathog. 2015 Feb 24;11(2):e1004677. doi: 10.1371/journal.ppat.1004677. eCollection 2015 Feb.

45.

Side-binding proteins modulate actin filament dynamics.

Crevenna AH, Arciniega M, Dupont A, Mizuno N, Kowalska K, Lange OF, Wedlich-Söldner R, Lamb DC.

Elife. 2015 Feb 23;4. pii: e04599. doi: 10.7554/eLife.04599.

46.

Super-resolved fluorescence microscopy: Nobel Prize in Chemistry 2014 for Eric Betzig, Stefan Hell, and William E. Moerner.

Möckl L, Lamb DC, Bräuchle C.

Angew Chem Int Ed Engl. 2014 Dec 15;53(51):13972-7. doi: 10.1002/anie.201410265. Epub 2014 Nov 4.

PMID:
25371081
47.

The lateral membrane organization and dynamics of myelin proteins PLP and MBP are dictated by distinct galactolipids and the extracellular matrix.

Ozgen H, Schrimpf W, Hendrix J, de Jonge JC, Lamb DC, Hoekstra D, Kahya N, Baron W.

PLoS One. 2014 Jul 8;9(7):e101834. doi: 10.1371/journal.pone.0101834. eCollection 2014.

48.

Investigating the role of F-actin in human immunodeficiency virus assembly by live-cell microscopy.

Rahman SA, Koch P, Weichsel J, Godinez WJ, Schwarz U, Rohr K, Lamb DC, Kräusslich HG, Müller B.

J Virol. 2014 Jul;88(14):7904-14. doi: 10.1128/JVI.00431-14. Epub 2014 Apr 30.

49.

Eukaryotic and archaeal TBP and TFB/TF(II)B follow different promoter DNA bending pathways.

Gietl A, Holzmeister P, Blombach F, Schulz S, von Voithenberg LV, Lamb DC, Werner F, Tinnefeld P, Grohmann D.

Nucleic Acids Res. 2014 Jun;42(10):6219-31. doi: 10.1093/nar/gku273. Epub 2014 Apr 17.

50.

Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties.

Abate C, Niso M, Marottoli R, Riganti C, Ghigo D, Ferorelli S, Ossato G, Perrone R, Lacivita E, Lamb DC, Berardi F.

J Med Chem. 2014 Apr 24;57(8):3314-23. doi: 10.1021/jm401874n. Epub 2014 Apr 14.

PMID:
24697311

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