Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51

1.

Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores.

McFarlane JS, Zhang J, Wang S, Lei X, Moran GR, Lamb AL.

J Biol Chem. 2019 Nov 22;294(47):17988-18001. doi: 10.1074/jbc.RA119.011059. Epub 2019 Oct 15.

PMID:
31615895
2.

Immune state is associated with natural dietary variation in wild mice Mus musculus domesticus.

Taylor CH, Young S, Fenn J, Lamb AL, Lowe AE, Poulin B, MacColl ADC, Bradley JE.

Funct Ecol. 2019 Aug;33(8):1425-1435. doi: 10.1111/1365-2435.13354. Epub 2019 May 22.

3.

Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation-π bond.

McFarlane JS, Ronnebaum TA, Meneely KM, Chilton A, Fenton AW, Lamb AL.

Acta Crystallogr F Struct Biol Commun. 2019 Jun 1;75(Pt 6):461-469. doi: 10.1107/S2053230X19007209. Epub 2019 Jun 10.

PMID:
31204694
4.

Multi-isotope analysis reveals that feasts in the Stonehenge environs and across Wessex drew people and animals from throughout Britain.

Madgwick R, Lamb AL, Sloane H, Nederbragt AJ, Albarella U, Pearson MP, Evans JA.

Sci Adv. 2019 Mar 13;5(3):eaau6078. doi: 10.1126/sciadv.aau6078. eCollection 2019 Mar.

5.

PvdF of pyoverdin biosynthesis is a structurally unique N10-formyltetrahydrofolate-dependent formyltransferase.

Kenjić N, Hoag MR, Moraski GC, Caperelli CA, Moran GR, Lamb AL.

Arch Biochem Biophys. 2019 Mar 30;664:40-50. doi: 10.1016/j.abb.2019.01.028. Epub 2019 Jan 26.

PMID:
30689984
6.

Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis.

Ronnebaum TA, McFarlane JS, Prisinzano TE, Booker SJ, Lamb AL.

Biochemistry. 2019 Feb 12;58(6):665-678. doi: 10.1021/acs.biochem.8b00716. Epub 2018 Dec 27.

PMID:
30525512
7.

The relationship between the phosphate and structural carbonate fractionation of fallow deer bioapatite in tooth enamel.

Miller H, Chenery C, Lamb AL, Sloane H, Carden RF, Atici L, Sykes N.

Rapid Commun Mass Spectrom. 2019 Jan 30;33(2):151-164. doi: 10.1002/rcm.8324.

8.

Not as easy as π: An insertional residue does not explain the π-helix gain-of-function in two-component FMN reductases.

McFarlane JS, Hagen RA, Chilton AS, Forbes DL, Lamb AL, Ellis HR.

Protein Sci. 2019 Jan;28(1):123-134. doi: 10.1002/pro.3504. Epub 2018 Nov 15.

PMID:
30171650
9.

An early Cambrian greenhouse climate.

Hearing TW, Harvey THP, Williams M, Leng MJ, Lamb AL, Wilby PR, Gabbott SE, Pohl A, Donnadieu Y.

Sci Adv. 2018 May 9;4(5):eaar5690. doi: 10.1126/sciadv.aar5690. eCollection 2018 May.

10.

Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase.

McFarlane JS, Davis CL, Lamb AL.

J Biol Chem. 2018 May 25;293(21):8009-8019. doi: 10.1074/jbc.RA118.002007. Epub 2018 Apr 4.

11.

Unraveling the Structure and Mechanism of the MST(ery) Enzymes.

Shelton CL, Lamb AL.

Trends Biochem Sci. 2018 May;43(5):342-357. doi: 10.1016/j.tibs.2018.02.011. Epub 2018 Mar 21. Review.

12.

Nonribosomal peptides for iron acquisition: pyochelin biosynthesis as a case study.

Ronnebaum TA, Lamb AL.

Curr Opin Struct Biol. 2018 Dec;53:1-11. doi: 10.1016/j.sbi.2018.01.015. Epub 2018 Feb 20. Review.

13.

Biosynthesis of an Opine Metallophore by Pseudomonas aeruginosa.

McFarlane JS, Lamb AL.

Biochemistry. 2017 Nov 14;56(45):5967-5971. doi: 10.1021/acs.biochem.7b00804. Epub 2017 Nov 3.

14.

Elevated salivary IgA, decreased anxiety, and an altered oral microbiota are associated with active participation on an undergraduate athletic team.

Lamb AL, Hess DE, Edenborn S, Ubinger E, Carrillo AE, Appasamy PM.

Physiol Behav. 2017 Feb 1;169:169-177. doi: 10.1016/j.physbeh.2016.12.004. Epub 2016 Dec 5.

PMID:
27932242
15.

A multi-isotope investigation of diet and subsistence amongst island and mainland populations from early medieval western Britain.

Hemer KA, Lamb AL, Chenery CA, Evans JA.

Am J Phys Anthropol. 2017 Mar;162(3):423-440. doi: 10.1002/ajpa.23127. Epub 2016 Nov 17.

16.

Ligand binding phenomena that pertain to the metabolic function of renalase.

Beaupre BA, Roman JV, Hoag MR, Meneely KM, Silvaggi NR, Lamb AL, Moran GR.

Arch Biochem Biophys. 2016 Dec 15;612:46-56. doi: 10.1016/j.abb.2016.10.011. Epub 2016 Oct 18.

17.

Holo Structure and Steady State Kinetics of the Thiazolinyl Imine Reductases for Siderophore Biosynthesis.

Meneely KM, Ronnebaum TA, Riley AP, Prisinzano TE, Lamb AL.

Biochemistry. 2016 Sep 27;55(38):5423-33. doi: 10.1021/acs.biochem.6b00735. Epub 2016 Sep 15.

18.

An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.

Meneely KM, Sundlov JA, Gulick AM, Moran GR, Lamb AL.

J Am Chem Soc. 2016 Jul 27;138(29):9277-93. doi: 10.1021/jacs.6b05134. Epub 2016 Jul 19.

19.

Breaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategy.

Lamb AL.

Biochim Biophys Acta. 2015 Aug;1854(8):1054-70. doi: 10.1016/j.bbapap.2015.05.001. Epub 2015 May 10. Review.

20.

You are lost without a map: Navigating the sea of protein structures.

Lamb AL, Kappock TJ, Silvaggi NR.

Biochim Biophys Acta. 2015 Apr;1854(4):258-68. doi: 10.1016/j.bbapap.2014.12.021. Epub 2014 Dec 29. Review.

21.

Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans.

George-Raizen JB, Shockley KR, Trojanowski NF, Lamb AL, Raizen DM.

Biol Open. 2014 Oct 31;3(11):1139-49. doi: 10.1242/bio.20147500.

22.

Structure of an Aspergillus fumigatus old yellow enzyme (EasA) involved in ergot alkaloid biosynthesis.

Chilton AS, Ellis AL, Lamb AL.

Acta Crystallogr F Struct Biol Commun. 2014 Oct;70(Pt 10):1328-32. doi: 10.1107/S2053230X14018962. Epub 2014 Sep 25.

23.

Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.

Meneely KM, Luo Q, Riley AP, Taylor B, Roy A, Stein RL, Prisinzano TE, Lamb AL.

Bioorg Med Chem. 2014 Nov 1;22(21):5961-9. doi: 10.1016/j.bmc.2014.09.010. Epub 2014 Sep 16.

24.

Compensating for the absence of selenocysteine in high-molecular weight thioredoxin reductases: the electrophilic activation hypothesis.

Lothrop AP, Snider GW, Flemer S Jr, Ruggles EL, Davidson RS, Lamb AL, Hondal RJ.

Biochemistry. 2014 Feb 4;53(4):664-74. doi: 10.1021/bi4007258. Epub 2014 Jan 23.

25.

Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities.

Meneely KM, Luo Q, Lamb AL.

Arch Biochem Biophys. 2013 Nov 1;539(1):70-80. doi: 10.1016/j.abb.2013.09.007. Epub 2013 Sep 19.

26.

Lysine221 is the general base residue of the isochorismate synthase from Pseudomonas aeruginosa (PchA) in a reaction that is diffusion limited.

Meneely KM, Luo Q, Dhar P, Lamb AL.

Arch Biochem Biophys. 2013 Oct 1;538(1):49-56. doi: 10.1016/j.abb.2013.07.026. Epub 2013 Aug 11.

27.

DAF-16/FOXO regulates homeostasis of essential sleep-like behavior during larval transitions in C. elegans.

Driver RJ, Lamb AL, Wyner AJ, Raizen DM.

Curr Biol. 2013 Mar 18;23(6):501-6. doi: 10.1016/j.cub.2013.02.009. Epub 2013 Mar 7.

28.
29.

Modification of residue 42 of the active site loop with a lysine-mimetic side chain rescues isochorismate-pyruvate lyase activity in Pseudomonas aeruginosa PchB.

Olucha J, Meneely KM, Lamb AL.

Biochemistry. 2012 Sep 25;51(38):7525-32. doi: 10.1021/bi300472n. Epub 2012 Sep 12.

30.

The oxygen isotope relationship between the phosphate and structural carbonate fractions of human bioapatite.

Chenery CA, Pashley V, Lamb AL, Sloane HJ, Evans JA.

Rapid Commun Mass Spectrom. 2012 Feb 15;26(3):309-19. doi: 10.1002/rcm.5331.

PMID:
22223318
31.

Mechanistic and structural studies of the N-hydroxylating flavoprotein monooxygenases.

Olucha J, Lamb AL.

Bioorg Chem. 2011 Dec;39(5-6):171-7. doi: 10.1016/j.bioorg.2011.07.006. Epub 2011 Aug 5. Review.

32.

Pericyclic reactions catalyzed by chorismate-utilizing enzymes.

Lamb AL.

Biochemistry. 2011 Sep 6;50(35):7476-83. doi: 10.1021/bi2009739. Epub 2011 Aug 12. Review.

33.

Two structures of an N-hydroxylating flavoprotein monooxygenase: ornithine hydroxylase from Pseudomonas aeruginosa.

Olucha J, Meneely KM, Chilton AS, Lamb AL.

J Biol Chem. 2011 Sep 9;286(36):31789-98. doi: 10.1074/jbc.M111.265876. Epub 2011 Jul 13.

34.

pH Dependence of catalysis by Pseudomonas aeruginosa isochorismate-pyruvate lyase: implications for transition state stabilization and the role of lysine 42.

Olucha J, Ouellette AN, Luo Q, Lamb AL.

Biochemistry. 2011 Aug 23;50(33):7198-207. doi: 10.1021/bi200599j. Epub 2011 Jul 22.

35.

Entropic and enthalpic components of catalysis in the mutase and lyase activities of Pseudomonas aeruginosa PchB.

Luo Q, Meneely KM, Lamb AL.

J Am Chem Soc. 2011 May 11;133(18):7229-33. doi: 10.1021/ja202091a. Epub 2011 Apr 19.

36.

Multi-tissue analysis of oxygen isotopes in wild rhesus macaques (Macaca mulatta).

Chenery CA, Lamb AL, O'Regan HJ, Elton S.

Rapid Commun Mass Spectrom. 2011 Mar 30;25(6):779-88. doi: 10.1002/rcm.4916.

PMID:
21337640
37.

Structure of Escherichia coli malate dehydrogenase at 1.45 A resolution.

Zaitseva J, Meneely KM, Lamb AL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Sep 1;65(Pt 9):866-9. doi: 10.1107/S1744309109032217. Epub 2009 Aug 20.

38.

Expression, purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of a Chlamydia trachomatis OmpR/PhoB-subfamily response regulator homolog, ChxR.

Hickey JM, Hefty PS, Lamb AL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt 8):791-4. doi: 10.1107/S1744309109025184. Epub 2009 Jul 25.

40.

Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction.

Meneely KM, Barr EW, Bollinger JM Jr, Lamb AL.

Biochemistry. 2009 May 26;48(20):4371-6. doi: 10.1021/bi900442z.

41.

Modern macaque dietary heterogeneity assessed using stable isotope analysis of hair and bone.

O'Regan HJ, Chenery C, Lamb AL, Stevens RE, Rook L, Elton S.

J Hum Evol. 2008 Oct;55(4):617-26. doi: 10.1016/j.jhevol.2008.05.001. Epub 2008 Jul 2.

PMID:
18599109
43.

Two crystal structures of the isochorismate pyruvate lyase from Pseudomonas aeruginosa.

Zaitseva J, Lu J, Olechoski KL, Lamb AL.

J Biol Chem. 2006 Nov 3;281(44):33441-9. Epub 2006 Aug 16.

44.

The outcomes of using self-study modules in energy conservation education for people with multiple sclerosis.

Lamb AL, Finlayson M, Mathiowetz V, Chen HY.

Clin Rehabil. 2005 Aug;19(5):475-81.

PMID:
16119402
45.

Heterodimeric structure of superoxide dismutase in complex with its metallochaperone.

Lamb AL, Torres AS, O'Halloran TV, Rosenzweig AC.

Nat Struct Biol. 2001 Sep;8(9):751-5.

PMID:
11524675
46.

Heterodimer formation between superoxide dismutase and its copper chaperone.

Lamb AL, Torres AS, O'Halloran TV, Rosenzweig AC.

Biochemistry. 2000 Dec 5;39(48):14720-7.

PMID:
11101286
47.

Structural basis for copper transfer by the metallochaperone for the Menkes/Wilson disease proteins.

Wernimont AK, Huffman DL, Lamb AL, O'Halloran TV, Rosenzweig AC.

Nat Struct Biol. 2000 Sep;7(9):766-71.

PMID:
10966647
48.

Crystal structure of the second domain of the human copper chaperone for superoxide dismutase.

Lamb AL, Wernimont AK, Pufahl RA, O'Halloran TV, Rosenzweig AC.

Biochemistry. 2000 Feb 22;39(7):1589-95.

PMID:
10677207
49.

Crystal structure of the copper chaperone for superoxide dismutase.

Lamb AL, Wernimont AK, Pufahl RA, Culotta VC, O'Halloran TV, Rosenzweig AC.

Nat Struct Biol. 1999 Aug;6(8):724-9.

PMID:
10426947
50.

Supplemental Content

Support Center