Sort by
Items per page

Send to

Choose Destination

Search results

Items: 50


The chemokine CCL7 regulates invadopodia maturation and MMP-9 mediated collagen degradation in liver-metastatic carcinoma cells.

Qi S, Perrino S, Miao X, Lamarche-Vane N, Brodt P.

Cancer Lett. 2020 Mar 23. pii: S0304-3835(20)30137-3. doi: 10.1016/j.canlet.2020.03.018. [Epub ahead of print]


The calcium-activated protease calpain regulates netrin-1 receptor deleted in colorectal cancer-induced axon outgrowth in cortical neurons.

Duquette PM, Lamarche-Vane N.

J Neurochem. 2020 Feb;152(3):315-332. doi: 10.1111/jnc.14837. Epub 2019 Aug 22.


Regulators of Rho GTPases in the Nervous System: Molecular Implication in Axon Guidance and Neurological Disorders.

Niftullayev S, Lamarche-Vane N.

Int J Mol Sci. 2019 Mar 25;20(6). pii: E1497. doi: 10.3390/ijms20061497. Review.


Collagen IV-conveyed signals can regulate chemokine production and promote liver metastasis.

Vaniotis G, Rayes RF, Qi S, Milette S, Wang N, Perrino S, Bourdeau F, Nyström H, He Y, Lamarche-Vane N, Brodt P.

Oncogene. 2018 Jul;37(28):3790-3805. doi: 10.1038/s41388-018-0242-z. Epub 2018 Apr 13.


CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein.

Ben Djoudi Ouadda A, He Y, Calabrese V, Ishii H, Chidiac R, Gratton JP, Roux PP, Lamarche-Vane N.

Oncotarget. 2018 Jan 10;9(14):11646-11664. doi: 10.18632/oncotarget.24126. eCollection 2018 Feb 20.


The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts.

McCormack JJ, Bruche S, Ouadda ABD, Ishii H, Lu H, Garcia-Cattaneo A, Chávez-Olórtegui C, Lamarche-Vane N, Braga VMM.

Sci Rep. 2017 Aug 23;7(1):9249. doi: 10.1038/s41598-017-09024-4.


Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides.

Pan X, De Aragão CBP, Velasco-Martin JP, Priestman DA, Wu HY, Takahashi K, Yamaguchi K, Sturiale L, Garozzo D, Platt FM, Lamarche-Vane N, Morales CR, Miyagi T, Pshezhetsky AV.

FASEB J. 2017 Aug;31(8):3467-3483. doi: 10.1096/fj.201601299R. Epub 2017 Apr 25.


The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer.

He Y, Northey JJ, Pelletier A, Kos Z, Meunier L, Haibe-Kains B, Mes-Masson AM, Côté JF, Siegel PM, Lamarche-Vane N.

Oncogene. 2017 Jun 15;36(24):3490-3503. doi: 10.1038/onc.2016.492. Epub 2017 Jan 30.


Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function.

Berryer MH, Chattopadhyaya B, Xing P, Riebe I, Bosoi C, Sanon N, Antoine-Bertrand J, Lévesque M, Avoli M, Hamdan FF, Carmant L, Lamarche-Vane N, Lacaille JC, Michaud JL, Di Cristo G.

Nat Commun. 2016 Nov 9;7:13340. doi: 10.1038/ncomms13340.


CdGAP/ARHGAP31, a Cdc42/Rac1 GTPase regulator, is critical for vascular development and VEGF-mediated angiogenesis.

Caron C, DeGeer J, Fournier P, Duquette PM, Luangrath V, Ishii H, Karimzadeh F, Lamarche-Vane N, Royal I.

Sci Rep. 2016 Jun 7;6:27485. doi: 10.1038/srep27485.


A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects.

Stewart K, Gaitan Y, Shafer ME, Aoudjit L, Hu D, Sharma R, Tremblay M, Ishii H, Marcotte M, Stanga D, Tang YC, Boualia SK, Nguyen AH, Takano T, Lamarche-Vane N, Vidal S, Bouchard M.

PLoS Genet. 2016 Feb 9;12(2):e1005785. doi: 10.1371/journal.pgen.1005785. eCollection 2016 Feb.


Direct measurement of oscillatory RhoA activity in embryonic cortical neurons stimulated with the axon guidance cue netrin-1 using fluorescence resonance energy transfer.

Antoine-Bertrand J, Fu M, Lamarche-Vane N.

Biol Cell. 2016 May;108(5):115-26. doi: 10.1111/boc.201500077. Epub 2016 Feb 10.


p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance.

Antoine-Bertrand J, Duquette PM, Alchini R, Kennedy TE, Fournier AE, Lamarche-Vane N.

J Biol Chem. 2016 Feb 26;291(9):4589-602. doi: 10.1074/jbc.M115.674846. Epub 2015 Dec 28.


Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1.

DeGeer J, Kaplan A, Mattar P, Morabito M, Stochaj U, Kennedy TE, Debant A, Cayouette M, Fournier AE, Lamarche-Vane N.

J Cell Biol. 2015 Aug 31;210(5):817-32. doi: 10.1083/jcb.201505084.


CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.

Pal R, Ramdzan ZM, Kaur S, Duquette PM, Marcotte R, Leduy L, Davoudi S, Lamarche-Vane N, Iulianella A, Nepveu A.

J Biol Chem. 2015 Sep 11;290(37):22520-31. doi: 10.1074/jbc.M115.651042. Epub 2015 Jul 28.


Rho GTPases in embryonic development.

Duquette PM, Lamarche-Vane N.

Small GTPases. 2014;5(2):8. doi: 10.4161/sgtp.29716. Review.


Rho GTPases in neurodegeneration diseases.

DeGeer J, Lamarche-Vane N.

Exp Cell Res. 2013 Sep 10;319(15):2384-94. doi: 10.1016/j.yexcr.2013.06.016. Epub 2013 Jul 2. Review.


Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth.

DeGeer J, Boudeau J, Schmidt S, Bedford F, Lamarche-Vane N, Debant A.

Mol Cell Biol. 2013 Feb;33(4):739-51. doi: 10.1128/MCB.01264-12. Epub 2012 Dec 10.


A stretch of polybasic residues mediates Cdc42 GTPase-activating protein (CdGAP) binding to phosphatidylinositol 3,4,5-trisphosphate and regulates its GAP activity.

Karimzadeh F, Primeau M, Mountassif D, Rouiller I, Lamarche-Vane N.

J Biol Chem. 2012 Jun 1;287(23):19610-21. doi: 10.1074/jbc.M112.344606. Epub 2012 Apr 19.


The activation of ezrin-radixin-moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1-induced axon outgrowth.

Antoine-Bertrand J, Ghogha A, Luangrath V, Bedford FK, Lamarche-Vane N.

Mol Biol Cell. 2011 Oct;22(19):3734-46. doi: 10.1091/mbc.E10-11-0917. Epub 2011 Aug 17.


Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies.

Southgate L, Machado RD, Snape KM, Primeau M, Dafou D, Ruddy DM, Branney PA, Fisher M, Lee GJ, Simpson MA, He Y, Bradshaw TY, Blaumeiser B, Winship WS, Reardon W, Maher ER, FitzPatrick DR, Wuyts W, Zenker M, Lamarche-Vane N, Trembath RC.

Am J Hum Genet. 2011 May 13;88(5):574-85. doi: 10.1016/j.ajhg.2011.04.013.


Implication of rho GTPases in neurodegenerative diseases.

Antoine-Bertrand J, Villemure JF, Lamarche-Vane N.

Curr Drug Targets. 2011 Jul 1;12(8):1202-15. Review.


Cdc42 GTPase-activating protein (CdGAP) interacts with the SH3D domain of Intersectin through a novel basic-rich motif.

Primeau M, Ben Djoudi Ouadda A, Lamarche-Vane N.

FEBS Lett. 2011 Mar 23;585(6):847-53. doi: 10.1016/j.febslet.2011.02.022. Epub 2011 Feb 22.


CdGAP is required for transforming growth factor β- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

He Y, Northey JJ, Primeau M, Machado RD, Trembath R, Siegel PM, Lamarche-Vane N.

Oncogene. 2011 Mar 3;30(9):1032-45. doi: 10.1038/onc.2010.477. Epub 2010 Nov 1.


Spatial and temporal activation of the small GTPases RhoA and Rac1 by the netrin-1 receptor UNC5a during neurite outgrowth.

Picard M, Petrie RJ, Antoine-Bertrand J, Saint-Cyr-Proulx E, Villemure JF, Lamarche-Vane N.

Cell Signal. 2009 Dec;21(12):1961-73. doi: 10.1016/j.cellsig.2009.09.004. Epub 2009 Sep 13.


Rab35 regulates neurite outgrowth and cell shape.

Chevallier J, Koop C, Srivastava A, Petrie RJ, Lamarche-Vane N, Presley JF.

FEBS Lett. 2009 Apr 2;583(7):1096-101. doi: 10.1016/j.febslet.2009.03.012. Epub 2009 Mar 14.


An adaptor role for cytoplasmic Sam68 in modulating Src activity during cell polarization.

Huot ME, Brown CM, Lamarche-Vane N, Richard S.

Mol Cell Biol. 2009 Apr;29(7):1933-43. doi: 10.1128/MCB.01707-08. Epub 2009 Jan 12.


Compartmentalized DCC signalling is distinct from DCC localized to lipid rafts.

Petrie RJ, Zhao B, Bedford F, Lamarche-Vane N.

Biol Cell. 2009 Feb;101(2):77-90. doi: 10.1042/BC20070108.


[A brief overview of the small Rho GTPases].

Primeau M, Lamarche-Vane N.

Med Sci (Paris). 2008 Feb;24(2):157-62. doi: 10.1051/medsci/2008242157. Review. French.


Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

Briançon-Marjollet A, Ghogha A, Nawabi H, Triki I, Auziol C, Fromont S, Piché C, Enslen H, Chebli K, Cloutier JF, Castellani V, Debant A, Lamarche-Vane N.

Mol Cell Biol. 2008 Apr;28(7):2314-23. doi: 10.1128/MCB.00998-07. Epub 2008 Jan 22.


Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury.

Zhang H, Cybulsky AV, Aoudjit L, Zhu J, Li H, Lamarche-Vane N, Takano T.

Am J Physiol Renal Physiol. 2007 Jul;293(1):F148-56. Epub 2007 Mar 20.


Current knowledge of the large RhoGAP family of proteins.

Tcherkezian J, Lamarche-Vane N.

Biol Cell. 2007 Feb;99(2):67-86. Review.


Glycogen synthase kinase-3 phosphorylates CdGAP at a consensus ERK 1 regulatory site.

Danek EI, Tcherkezian J, Triki I, Meriane M, Lamarche-Vane N.

J Biol Chem. 2007 Feb 9;282(6):3624-31. Epub 2006 Dec 8.


CdGAP associates with actopaxin to regulate integrin-dependent changes in cell morphology and motility.

LaLonde DP, Grubinger M, Lamarche-Vane N, Turner CE.

Curr Biol. 2006 Jul 25;16(14):1375-85.


Adenovirus E4orf4 hijacks rho GTPase-dependent actin dynamics to kill cells: a role for endosome-associated actin assembly.

Robert A, Smadja-Lamère N, Landry MC, Champagne C, Petrie R, Lamarche-Vane N, Hosoya H, Lavoie JN.

Mol Biol Cell. 2006 Jul;17(7):3329-44. Epub 2006 May 10.


The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.

Tcherkezian J, Triki I, Stenne R, Danek EI, Lamarche-Vane N.

Biol Cell. 2006 Aug;98(8):445-56.


Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory site.

Tcherkezian J, Danek EI, Jenna S, Triki I, Lamarche-Vane N.

Mol Cell Biol. 2005 Aug;25(15):6314-29.


Cyclic AMP induces morphological changes of vascular smooth muscle cells by inhibiting a Rac-dependent signaling pathway.

Pelletier S, Julien C, Popoff MR, Lamarche-Vane N, Meloche S.

J Cell Physiol. 2005 Aug;204(2):412-22.


Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance.

Meriane M, Tcherkezian J, Webber CA, Danek EI, Triki I, McFarlane S, Bloch-Gallego E, Lamarche-Vane N.

J Cell Biol. 2004 Nov 22;167(4):687-98.


A novel testicular RhoGAP-domain protein induces apoptosis.

Modarressi MH, Cheng M, Tarnasky HA, Lamarche-Vane N, de Rooij DG, Ruan Y, van der Hoorn FA.

Biol Reprod. 2004 Dec;71(6):1980-90. Epub 2004 Aug 11.


The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism.

Li X, Meriane M, Triki I, Shekarabi M, Kennedy TE, Larose L, Lamarche-Vane N.

J Biol Chem. 2002 Oct 4;277(40):37788-97. Epub 2002 Jul 30.


The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin.

Jenna S, Hussain NK, Danek EI, Triki I, Wasiak S, McPherson PS, Lamarche-Vane N.

J Biol Chem. 2002 Feb 22;277(8):6366-73. Epub 2001 Dec 13.


Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP.

Hussain NK, Jenna S, Glogauer M, Quinn CC, Wasiak S, Guipponi M, Antonarakis SE, Kay BK, Stossel TP, Lamarche-Vane N, McPherson PS.

Nat Cell Biol. 2001 Oct;3(10):927-32.


Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.

Prakash SK, Paylor R, Jenna S, Lamarche-Vane N, Armstrong DL, Xu B, Mancini MA, Zoghbi HY.

Hum Mol Genet. 2000 Mar 1;9(4):477-88.


CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.

Lamarche-Vane N, Hall A.

J Biol Chem. 1998 Oct 30;273(44):29172-7.

Supplemental Content

Loading ...
Support Center