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PIEZO2 mediates injury-induced tactile pain in mice and humans.

Szczot M, Liljencrantz J, Ghitani N, Barik A, Lam R, Thompson JH, Bharucha-Goebel D, Saade D, Necaise A, Donkervoort S, Foley AR, Gordon T, Case L, Bushnell MC, Bönnemann CG, Chesler AT.

Sci Transl Med. 2018 Oct 10;10(462). pii: eaat9892. doi: 10.1126/scitranslmed.aat9892.


Development of a Multistep Hypertension Quality Improvement Program in an Academic General Medicine Practice.

Bui-Duy MK, Wong S, Lam R, Karliner LS.

J Healthc Qual. 2018 Oct 8. doi: 10.1097/JHQ.0000000000000158. [Epub ahead of print]


Metabolomics of World Trade Center-Lung Injury: a machine learning approach.

Crowley G, Kwon S, Haider SH, Caraher EJ, Lam R, St-Jules DE, Liu M, Prezant DJ, Nolan A.

BMJ Open Respir Res. 2018 Sep 3;5(1):e000274. doi: 10.1136/bmjresp-2017-000274. eCollection 2018.


Early change in reward and punishment sensitivity as a predictor of response to antidepressant treatment for major depressive disorder: a CAN-BIND-1 report.

Allen TA, Lam RW, Milev R, Rizvi SJ, Frey BN, MacQueen GM, Müller DJ, Uher R, Kennedy SH, Quilty LC.

Psychol Med. 2018 Sep 17:1-10. doi: 10.1017/S0033291718002441. [Epub ahead of print]


A Comparison of Electronic Patient-Portal Use Among Patients with Resident and Attending Primary Care Providers.

Chan B, Lyles C, Kaplan C, Lam R, Karliner L.

J Gen Intern Med. 2018 Sep 5. doi: 10.1007/s11606-018-4637-x. [Epub ahead of print]


Evidence for the Efficacy of Bright Light Therapy for Bipolar Depression.

Benedetti F, Avery DH, Bauer M, Bunney WE, Çaliyurt O, Camardese G, Colombo C, Dallaspezia S, Henriksen TE, Kasper S, Kuriyama K, Lam RW, Martiny K, Meesters Y, Mishima K, Schulte R, Suzuki M, Święcicki Ł, Uchiyama M, Veale D, Winkler D, Wu J, Kupeli NY, Yoshiike T, Yu X.

Am J Psychiatry. 2018 Sep 1;175(9):905-906. doi: 10.1176/appi.ajp.2018.18020231. No abstract available.


Prevalence of tuberculosis infection and disease in children referred for tuberculosis medical surveillance in Ontario: a single-cohort study.

Yang C, Yasseen AS 3rd, Stimec J, Rea E, Waters V, Lam R, Morris SK, Kitai I.

CMAJ Open. 2018 Aug 28;6(3):E365-E371. doi: 10.9778/cmajo.20180043. Print 2018 Jul-Sep.


Microfluidic implementation of functional cytometric microbeads for improved multiplexed cytokine quantification.

Liu Y, Li J, Hu D, Lam JHM, Sun D, Pang SW, Lam RHW.

Biomicrofluidics. 2018 Aug 10;12(4):044112. doi: 10.1063/1.5044449. eCollection 2018 Jul.


Stability, reliability, and validity of the THINC-it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers.

Harrison JE, Barry H, Baune BT, Best MW, Bowie CR, Cha DS, Culpepper L, Fossati P, Greer TL, Harmer C, Klag E, Lam RW, Lee Y, Mansur RB, Wittchen HU, McIntyre RS.

Int J Methods Psychiatr Res. 2018 Sep;27(3):e1736. doi: 10.1002/mpr.1736. Epub 2018 Aug 7.


Appetitive Symptoms Differentially Predict Treatment Response to Fluoxetine, Light, and Placebo in Nonseasonal Major Depression.

Levitan RD, Levitt AJ, Michalak EE, Morehouse R, Ramasubbu R, Yatham LN, Tam EM, Lam RW.

J Clin Psychiatry. 2018 Jul 24;79(4). pii: 17m11856. doi: 10.4088/JCP.17m11856.


Retraction of "Substrate Stiffness Regulates the Development of Left-Right Asymmetry in Cell Orientation".

Bao Y, Huang Y, Lam ML, Xu T, Zhu N, Guo Z, Cui X, Lam RHW, Chen TH.

ACS Appl Mater Interfaces. 2018 Aug 1;10(30):25831. doi: 10.1021/acsami.8b10621. Epub 2018 Jul 20. No abstract available.


A randomized clinical trial of the efficacy and safety of sitagliptin compared with dapagliflozin in patients with type 2 diabetes mellitus and mild renal insufficiency: The CompoSIT-R study.

Scott R, Morgan J, Zimmer Z, Lam RLH, O'Neill EA, Kaufman KD, Engel SS, Raji A.

Diabetes Obes Metab. 2018 Jul 18. doi: 10.1111/dom.13473. [Epub ahead of print]


Effectiveness of a multidisciplinary approach to geriatric hip fractures in improving clinical outcomes and cost of care.

Leung FK, Lau TW, Yuen GW, Chan EM, Chan P, Lam RY.

Hong Kong Med J. 2018 Feb;24 Suppl 2(1):45-47. No abstract available.


Efficacy and Safety of Sitagliptin in Hispanic/Latino Patients with Type 2 Diabetes: A Pooled Analysis from Ten Randomized, Placebo-Controlled Phase 3 Clinical Trials.

Raji A, Long J, Lam RLH, O'Neill EA, Engel SS.

Diabetes Ther. 2018 Jun 23. doi: 10.1007/s13300-018-0461-x. [Epub ahead of print]


The association of duration and severity of disease with executive function: Differences between drug-naïve patients with bipolar and unipolar depression.

Yang T, Zhao G, Mao R, Huang J, Xu X, Su Y, Zhu N, Zhou R, Lin X, Xia W, Wang F, Liu R, Wang X, Huang Z, Wang Y, Hu Y, Cao L, Yuan C, Wang Z, Lam RW, Chen J, Fang Y.

J Affect Disord. 2018 Oct 1;238:412-417. doi: 10.1016/j.jad.2018.05.051. Epub 2018 May 29.


Shear elegance: A novel screen uncovers a mechanosensitive GPCR.

Lam RM, Chesler AT.

J Gen Physiol. 2018 Jul 2;150(7):907-910. doi: 10.1085/jgp.201812101. Epub 2018 Jun 14. No abstract available.


Efficacy and safety of MK-1293 insulin glargine compared with originator insulin glargine (Lantus) in type 1 diabetes: A randomized, open-label clinical trial.

Home PD, Lam RLH, Carofano WL, Golm GT, Eldor R, Crutchlow MF, Marcos MC, Rosenstock J, Hollander PA, Gallwitz B.

Diabetes Obes Metab. 2018 Sep;20(9):2220-2228. doi: 10.1111/dom.13354. Epub 2018 Jun 5.


Efficacy and safety of MK-1293 insulin glargine compared with originator insulin glargine (Lantus) in type 2 diabetes: A randomized, open-label clinical trial.

Hollander PA, Carofano WL, Lam RLH, Golm GT, Eldor R, Crutchlow MF, Marcos MC, Rendell MS, Home PD, Gallwitz B, Rosenstock J.

Diabetes Obes Metab. 2018 Sep;20(9):2229-2237. doi: 10.1111/dom.13363. Epub 2018 Jun 10.


Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial.

Blumberger DM, Vila-Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, Knyahnytska Y, Kennedy SH, Lam RW, Daskalakis ZJ, Downar J.

Lancet. 2018 Apr 28;391(10131):1683-1692. doi: 10.1016/S0140-6736(18)30295-2. Epub 2018 Apr 26. Erratum in: Lancet. 2018 Jun 23;391(10139):e24.


A simplified sheathless cell separation approach using combined gravitational-sedimentation-based prefocusing and dielectrophoretic separation.

Luo T, Fan L, Zeng Y, Liu Y, Chen S, Tan Q, Lam RHW, Sun D.

Lab Chip. 2018 May 29;18(11):1521-1532. doi: 10.1039/c8lc00173a.


Use of Placebo in Clinical Trials of Psychotropic Medication.

Hasnain M, Rudnick A, Bonnell WS, Remington G, Lam RW.

Can J Psychiatry. 2018 May;63(5):338-341. doi: 10.1177/0706743717752917.


Hyperbaric oxygen therapy: its use in medical emergencies and its development in Hong Kong.

Leung JK, Lam RP.

Hong Kong Med J. 2018 Apr;24(2):191-199. doi: 10.12809/hkmj176875.


Abnormal Functional Connectivity of Frontopolar Subregions in Treatment-Nonresponsive Major Depressive Disorder.

Fettes PW, Moayedi M, Dunlop K, Mansouri F, Vila-Rodriguez F, Giacobbe P, Davis KD, Lam RW, Kennedy SH, Daskalakis ZJ, Blumberger DM, Downar J.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Apr;3(4):337-347. doi: 10.1016/j.bpsc.2017.12.003. Epub 2017 Dec 27.


Identifying the Priority Topics for the Assessment of Competence in Care of the Elderly.

Charles LA, Frank CC, Allen T, Lozanovska T, Arcand M, Feldman S, Lam RE, Mehta PG, Mangal NY.

Can Geriatr J. 2018 Mar 26;21(1):6-13. doi: 10.5770/cgj.21.289. eCollection 2018 Mar.


Acupuncture in the emergency department: a systematic review of randomised controlled trials.

Chia KL, Lam RPK, Lam CK, Tsui SH.

Acupunct Med. 2018 Jun;36(3):183-192. doi: 10.1136/acupmed-2017-011547. Epub 2018 Mar 26.


Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.

Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, Sharma V, Goldstein BI, Rej S, Beaulieu S, Alda M, MacQueen G, Milev RV, Ravindran A, O'Donovan C, McIntosh D, Lam RW, Vazquez G, Kapczinski F, McIntyre RS, Kozicky J, Kanba S, Lafer B, Suppes T, Calabrese JR, Vieta E, Malhi G, Post RM, Berk M.

Bipolar Disord. 2018 Mar;20(2):97-170. doi: 10.1111/bdi.12609. Epub 2018 Mar 14.


Surgical management of a cat with hepatic arterioportal fistula.

Phillips A, Kulendra ER, Lam R, Kulendra NJ, Brockman DJ.

J Small Anim Pract. 2018 Mar 14. doi: 10.1111/jsap.12820. [Epub ahead of print]


Impact of altered phosphorylation on loss of function of juvenile Parkinsonism-associated genetic variants of the E3 ligase parkin.

Aguirre JD, Dunkerley KM, Lam R, Rusal M, Shaw GS.

J Biol Chem. 2018 Apr 27;293(17):6337-6348. doi: 10.1074/jbc.RA117.000605. Epub 2018 Mar 12.


Comprehensive Evaluation of the MBT STAR-BL Module for Simultaneous Bacterial Identification and β-Lactamase-Mediated Resistance Detection in Gram-Negative Rods from Cultured Isolates and Positive Blood Cultures.

Lee AWT, Lam JKS, Lam RKW, Ng WH, Lee ENL, Lee VTY, Sze PP, Rajwani R, Fung KSC, To WK, Lee RA, Tsang DNC, Siu GKH.

Front Microbiol. 2018 Feb 23;9:334. doi: 10.3389/fmicb.2018.00334. eCollection 2018.


Cognitive Impairment in Major Depressive Disorder: A Case Discussion Illustrating Impact, Assessment, and Management.

Culpepper L, Lam RW, McIntyre RS.

J Clin Psychiatry. 2018 Jan/Feb;79(1). pii: TK16043PD4C. doi: 10.4088/JCP.TK16043PD4C.


Predictive Biomarkers of Gastroesophageal Reflux Disease and Barrett's Esophagus in World Trade Center Exposed Firefighters: a 15 Year Longitudinal Study.

Haider SH, Kwon S, Lam R, Lee AK, Caraher EJ, Crowley G, Zhang L, Schwartz TM, Zeig-Owens R, Liu M, Prezant DJ, Nolan A.

Sci Rep. 2018 Feb 15;8(1):3106. doi: 10.1038/s41598-018-21334-9.


Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis.

Cui X, Morales RT, Qian W, Wang H, Gagner JP, Dolgalev I, Placantonakis D, Zagzag D, Cimmino L, Snuderl M, Lam RHW, Chen W.

Biomaterials. 2018 Apr;161:164-178. doi: 10.1016/j.biomaterials.2018.01.053. Epub 2018 Feb 3.


Soft X-Ray Second Harmonic Generation as an Interfacial Probe.

Lam RK, Raj SL, Pascal TA, Pemmaraju CD, Foglia L, Simoncig A, Fabris N, Miotti P, Hull CJ, Rizzuto AM, Smith JW, Mincigrucci R, Masciovecchio C, Gessini A, Allaria E, De Ninno G, Diviacco B, Roussel E, Spampinati S, Penco G, Di Mitri S, Trovò M, Danailov M, Christensen ST, Sokaras D, Weng TC, Coreno M, Poletto L, Drisdell WS, Prendergast D, Giannessi L, Principi E, Nordlund D, Saykally RJ, Schwartz CP.

Phys Rev Lett. 2018 Jan 12;120(2):023901. doi: 10.1103/PhysRevLett.120.023901.


Implications of Cannabis Legalization on Youth and Young Adults.

Tibbo P, Crocker CE, Lam RW, Meyer J, Sareen J, Aitchison KJ.

Can J Psychiatry. 2018 Jan;63(1):65-71. doi: 10.1177/0706743718759031. No abstract available.


Impact of Cognitive Impairment on Functioning in Patients With Depression.

Lam RW.

J Clin Psychiatry. 2017 Nov/Dec;78(9):e1430. doi: 10.4088/JCP.tk16043tx1c.


Cognitive Impairment in Patients With Depression: Awareness, Assessment, and Management.

Culpepper L, Lam RW, McIntyre RS.

J Clin Psychiatry. 2017 Nov/Dec;78(9):1383-1394. doi: 10.4088/JCP.tk16043ah5c. Review.


A fluorescent microbead-based microfluidic immunoassay chip for immune cell cytokine secretion quantification.

Cui X, Liu Y, Hu D, Qian W, Tin C, Sun D, Chen W, Lam RHW.

Lab Chip. 2018 Jan 30;18(3):522-531. doi: 10.1039/c7lc01183k.


Protein-Substrate Adhesion in Microcontact Printing Regulates Cell Behavior.

Hu S, Chen TH, Zhao Y, Wang Z, Lam RHW.

Langmuir. 2018 Jan 30;34(4):1750-1759. doi: 10.1021/acs.langmuir.7b02935. Epub 2018 Jan 18.


Fluorescently Labeled Morphine Derivatives for Bioimaging Studies.

Lam R, Gondin AB, Canals M, Kellam B, Briddon SJ, Graham B, Scammells PJ.

J Med Chem. 2018 Feb 8;61(3):1316-1329. doi: 10.1021/acs.jmedchem.7b01811. Epub 2018 Jan 10.


Clinical signs, imaging findings, and outcome in twelve cats with internal ophthalmoparesis/ophthalmoplegia.

Hamzianpour N, Lam R, Tetas R, Beltran E.

Vet Ophthalmol. 2018 Jul;21(4):382-390. doi: 10.1111/vop.12523. Epub 2017 Dec 28.


Painless aortic dissection presenting with multisystem organ failure and owl's eyes sign of the spinal cord.

Lam R, Swenson SL, Nuckton TJ, Nisam M.

BMJ Case Rep. 2017 Dec 13;2017. pii: bcr-2017-223185. doi: 10.1136/bcr-2017-223185. No abstract available.


Rapid postoperative recurrence of a cranial multilobular tumor of bone in a young dog.

Cook S, Civello A, Lam R, Fenn J, Neilson D, Priestnall S, Decker S.

Clin Case Rep. 2017 Oct 30;5(12):1995-1999. doi: 10.1002/ccr3.1243. eCollection 2017 Dec.


Rabbits with naturally occurring cataracts referred for phacoemulsification and intraocular lens implantation: a preliminary study of 12 cases.

Sanchez RF, Everson R, Hedley J, Dawson C, Lam R, Priestnall SL, Garcia de Carellan A, de Miguel C, Seymour C.

Vet Ophthalmol. 2018 Jul;21(4):399-412. doi: 10.1111/vop.12525. Epub 2017 Dec 4.


The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study.

Baskaran A, Farzan F, Milev R, Brenner CA, Alturi S, Pat McAndrews M, Blier P, Evans K, Foster JA, Frey BN, Giacobbe P, Lam RW, Leri F, MacQueen GM, Müller DJ, Parikh SV, Rotzinger S, Soares CN, Strother SC, Turecki G, Kennedy SH; CAN-BIND Investigators Team.

J Affect Disord. 2018 Feb;227:542-549. doi: 10.1016/j.jad.2017.10.028. Epub 2017 Nov 3.


A multicomponent intervention for the management of chronic pain in older adults: study protocol for a randomized controlled trial.

Cheng ST, Chan KL, Lam RWL, Mok MHT, Chen PP, Chow YF, Chung JWY, Law ACB, Lee JSW, Leung EMF, Tam CWC.

Trials. 2017 Nov 9;18(1):528. doi: 10.1186/s13063-017-2270-3.


Success rates of a skeletal anchorage system in orthodontics: A retrospective analysis.

Lam R, Goonewardene MS, Allan BP, Sugawara J.

Angle Orthod. 2018 Jan;88(1):27-34. doi: 10.2319/060617-375.1. Epub 2017 Oct 20.


Efficacy and tolerability of lisdexamfetamine as an antidepressant augmentation strategy: A meta-analysis of randomized controlled trials.

Giacobbe P, Rakita U, Lam R, Milev R, Kennedy SH, McIntyre RS.

J Affect Disord. 2018 Jan 15;226:294-300. doi: 10.1016/j.jad.2017.09.041. Epub 2017 Oct 3.


A Positron Emission Tomography Study of Norepinephrine Transporter Occupancy and Its Correlation with Symptom Response in Depressed Patients Treated with Quetiapine XR.

Yatham LN, Sossi V, Ding YS, Vafai N, Arumugham SS, Dhanoa T, Lam RW, Bond DJ, Puyat JH.

Int J Neuropsychopharmacol. 2018 Feb 1;21(2):108-113. doi: 10.1093/ijnp/pyx066.


Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial.

Holtzheimer PE, Husain MM, Lisanby SH, Taylor SF, Whitworth LA, McClintock S, Slavin KV, Berman J, McKhann GM, Patil PG, Rittberg BR, Abosch A, Pandurangi AK, Holloway KL, Lam RW, Honey CR, Neimat JS, Henderson JM, DeBattista C, Rothschild AJ, Pilitsis JG, Espinoza RT, Petrides G, Mogilner AY, Matthews K, Peichel D, Gross RE, Hamani C, Lozano AM, Mayberg HS.

Lancet Psychiatry. 2017 Nov;4(11):839-849. doi: 10.1016/S2215-0366(17)30371-1. Epub 2017 Oct 4.


Monitoring for antidepressant-associated adverse events in the treatment of patients with major depressive disorder: An international consensus statement.

Dodd S, Mitchell PB, Bauer M, Yatham L, Young AH, Kennedy SH, Williams L, Suppes T, Lopez Jaramillo C, Trivedi MH, Fava M, Rush AJ, McIntyre RS, Thase ME, Lam RW, Severus E, Kasper S, Berk M.

World J Biol Psychiatry. 2018 Aug;19(5):330-348. doi: 10.1080/15622975.2017.1379609. Epub 2017 Oct 6. Review. Erratum in: World J Biol Psychiatry. 2018 Aug;19(5):i.


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