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Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion.

Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY.

Nat Commun. 2019 Jun 13;10(1):2588. doi: 10.1038/s41467-019-10411-w.


Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation.

Zhang T, Guan X, Choi UL, Dong Q, Lam MMT, Zeng J, Xiong J, Wang X, Poon TCW, Zhang H, Zhang X, Wang H, Xie R, Zhu B, Li G.

Epigenetics Chromatin. 2019 Jun 4;12(1):32. doi: 10.1186/s13072-019-0281-x.


Revisiting Fragmentation Reactions of Protonated α-Amino Acids by High-Resolution Electrospray Ionization Tandem Mass Spectrometry with Collision-Induced Dissociation.

Zhang P, Chan W, Ang IL, Wei R, Lam MMT, Lei KMK, Poon TCW.

Sci Rep. 2019 Apr 23;9(1):6453. doi: 10.1038/s41598-019-42777-8.


Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae.

Wyres KL, Wick RR, Judd LM, Froumine R, Tokolyi A, Gorrie CL, Lam MMC, Duchêne S, Jenney A, Holt KE.

PLoS Genet. 2019 Apr 15;15(4):e1008114. doi: 10.1371/journal.pgen.1008114. eCollection 2019 Apr.


Angiotensin II promotes ovarian cancer spheroid formation and metastasis by upregulation of lipid desaturation and suppression of endoplasmic reticulum stress.

Zhang Q, Yu S, Lam MMT, Poon TCW, Sun L, Jiao Y, Wong AST, Lee LTO.

J Exp Clin Cancer Res. 2019 Mar 7;38(1):116. doi: 10.1186/s13046-019-1127-x.


Gas-Phase Fragmentation Reactions of Protonated Cystine using High-Resolution Tandem Mass Spectrometry.

Zhang P, Chan W, Ang IL, Wei R, Lam MMT, Lei KMK, Poon TCW.

Molecules. 2019 Feb 19;24(4). pii: E747. doi: 10.3390/molecules24040747.


Energization of the Ring Current by Substorms.

Sandhu JK, Rae IJ, Freeman MP, Forsyth C, Gkioulidou M, Reeves GD, Spence HE, Jackman CM, Lam MM.

J Geophys Res Space Phys. 2018 Oct;123(10):8131-8148. doi: 10.1029/2018JA025766. Epub 2018 Oct 8.


Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15.

Lam MMC, Wyres KL, Wick RR, Judd LM, Fostervold A, Holt KE, Löhr IH.

J Antimicrob Chemother. 2019 May 1;74(5):1218-1222. doi: 10.1093/jac/dkz028.


Aryl hydrocarbon receptor-mediated potencies in field-deployed plastics vary by type of polymer.

Schönlau C, Larsson M, Lam MM, Engwall M, Giesy JP, Rochman C, Kärrman A.

Environ Sci Pollut Res Int. 2019 Mar;26(9):9079-9088. doi: 10.1007/s11356-019-04281-4. Epub 2019 Feb 4.


Small IncQ1 and Col-Like Plasmids Harboring bla KPC-2 and Non-Tn4401 Elements (NTEKPC-IId) in High-Risk Lineages of Klebsiella pneumoniae CG258.

Cerdeira LT, Lam MMC, Wyres KL, Wick RR, Judd LM, Lopes R, Ribas RM, Morais MM, Holt KE, Lincopan N.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e02140-18. doi: 10.1128/AAC.02140-18. Print 2019 Mar. No abstract available.


Comment on: CG258 Klebsiella pneumoniae isolates without β-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City.

Wyres KL, Lam MMC, Holt KE.

J Antimicrob Chemother. 2019 Mar 1;74(3):831-833. doi: 10.1093/jac/dky472. No abstract available.


Assessment of the performance of blood glucose monitoring systems for monitoring dysglycaemia in neonatal patients.

Ba Y, Xu J, Yuan L, Zhu H, Yang Y, Lam MM, Zhang S, Xiao M, Xu J, Zhang R, Chen C.

BMJ Paediatr Open. 2018 Oct 23;2(1):e000339. doi: 10.1136/bmjpo-2018-000339. eCollection 2018.


Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae.

Lam MMC, Wyres KL, Judd LM, Wick RR, Jenney A, Brisse S, Holt KE.

Genome Med. 2018 Oct 29;10(1):77. doi: 10.1186/s13073-018-0587-5.


Increasing tolerance of hospital Enterococcus faecium to handwash alcohols.

Pidot SJ, Gao W, Buultjens AH, Monk IR, Guerillot R, Carter GP, Lee JYH, Lam MMC, Grayson ML, Ballard SA, Mahony AA, Grabsch EA, Kotsanas D, Korman TM, Coombs GW, Robinson JO, Gonçalves da Silva A, Seemann T, Howden BP, Johnson PDR, Stinear TP.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaar6115. doi: 10.1126/scitranslmed.aar6115.


Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination.

Lam MMC, Wyres KL, Duchêne S, Wick RR, Judd LM, Gan YH, Hoh CH, Archuleta S, Molton JS, Kalimuddin S, Koh TH, Passet V, Brisse S, Holt KE.

Nat Commun. 2018 Jul 13;9(1):2703. doi: 10.1038/s41467-018-05114-7.


Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations.

Lam MMC, Wick RR, Wyres KL, Gorrie CL, Judd LM, Jenney AWJ, Brisse S, Holt KE.

Microb Genom. 2018 Sep;4(9). doi: 10.1099/mgen.0.000196. Epub 2018 Jul 9.


Occurrence and leachability of polycyclic aromatic compounds in contaminated soils: Chemical and bioanalytical characterization.

Larsson M, Lam MM, van Hees P, Giesy JP, Engwall M.

Sci Total Environ. 2018 May 1;622-623:1476-1484. doi: 10.1016/j.scitotenv.2017.12.015. Epub 2017 Dec 19.


Methylated PACs are more potent than their parent compounds: A study of aryl hydrocarbon receptor-mediated activity, degradability, and mixture interactions in the H4IIE-luc assay.

Lam MM, Bülow R, Engwall M, Giesy JP, Larsson M.

Environ Toxicol Chem. 2018 May;37(5):1409-1419. doi: 10.1002/etc.4087. Epub 2018 Mar 26.


Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon-contaminated soils.

Lam MM, Engwall M, Denison MS, Larsson M.

Environ Toxicol Chem. 2018 Feb;37(2):385-397. doi: 10.1002/etc.3958. Epub 2017 Nov 6.


Evolutionary origins of the emergent ST796 clone of vancomycin resistant Enterococcus faecium.

Buultjens AH, Lam MM, Ballard S, Monk IR, Mahony AA, Grabsch EA, Grayson ML, Pang S, Coombs GW, Robinson JO, Seemann T, Johnson PD, Howden BP, Stinear TP.

PeerJ. 2017 Jan 24;5:e2916. doi: 10.7717/peerj.2916. eCollection 2017.


Stability of a frequency-comb-based transfer-lock using a passive Fabry-Perot resonator.

Pal SB, Lam MM, Dieckmann K.

Opt Lett. 2016 Dec 1;41(23):5527-5530. doi: 10.1364/OL.41.005527.


Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus.

He W, Tan GS, Mullarkey CE, Lee AJ, Lam MM, Krammer F, Henry C, Wilson PC, Ashkar AA, Palese P, Miller MS.

Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11931-11936. Epub 2016 Oct 3.


Abnormal regulation of the antiviral response in neurological/neurodegenerative diseases.

Lam MM, Mapletoft JP, Miller MS.

Cytokine. 2016 Dec;88:251-258. doi: 10.1016/j.cyto.2016.09.002. Epub 2016 Sep 30. Review.


Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk: A Meta-analytical Stratification.

Fusar-Poli P, Cappucciati M, Borgwardt S, Woods SW, Addington J, Nelson B, Nieman DH, Stahl DR, Rutigliano G, Riecher-Rössler A, Simon AE, Mizuno M, Lee TY, Kwon JS, Lam MM, Perez J, Keri S, Amminger P, Metzler S, Kawohl W, Rössler W, Lee J, Labad J, Ziermans T, An SK, Liu CC, Woodberry KA, Braham A, Corcoran C, McGorry P, Yung AR, McGuire PK.

JAMA Psychiatry. 2016 Feb;73(2):113-20. doi: 10.1001/jamapsychiatry.2015.2324.


Correction: Whole Genome Comparisons Suggest Random Distribution of Mycobacterium ulcerans Genotypes in a Buruli Ulcer Endemic Region of Ghana.

Ablordey AS, Vandelannoote K, Frimpong IA, Ahortor EK, Amissah NA, Eddyani M, Durnez L, Portaels F, de Jong BC, Leirs H, Porter JL, Mangas KM, Lam MM, Buultjens A, Seemann T, Tobias NJ, Stinear TP.

PLoS Negl Trop Dis. 2015 May 13;9(5):e0003798. doi: 10.1371/journal.pntd.0003798. eCollection 2015 May. No abstract available.


Three-year community case management for early psychosis: a randomised controlled study.

Chen EY, Chang WC, Chan SK, Lam MM, Hung SF, Chung DW, Hui CL, Wong GH, Au Yang WS, Tang JY.

Hong Kong Med J. 2015 Apr;21 Suppl 2:23-6. No abstract available.


Early intervention versus standard care for psychosis in Hong Kong: a 10-year study.

Chan SK, Chen EY, Tang JY, Chiu CP, Lam MM, Chung DW, Tso S, Hung SF, Yip KC, Dunn EL.

Hong Kong Med J. 2015 Apr;21 Suppl 2:19-22. No abstract available.


Whole genome comparisons suggest random distribution of Mycobacterium ulcerans genotypes in a Buruli ulcer endemic region of Ghana.

Ablordey AS, Vandelannoote K, Frimpong IA, Ahortor EK, Amissah NA, Eddyani M, Durnez L, Portaels F, de Jong BC, Leirs H, Porter JL, Mangas KM, Lam MM, Buultjens A, Seemann T, Tobias NJ, Stinear TP.

PLoS Negl Trop Dis. 2015 Mar 31;9(3):e0003681. doi: 10.1371/journal.pntd.0003681. eCollection 2015 Mar. Erratum in: PLoS Negl Trop Dis. 2015 May;9(5):e0003798.


Tracking diet preferences of bats using stable isotope and fatty acid signatures of faeces.

Lam MM, Martin-Creuzburg D, Rothhaupt KO, Safi K, Yohannes E, Salvarina I.

PLoS One. 2013 Dec 23;8(12):e83452. doi: 10.1371/journal.pone.0083452. eCollection 2013.


Comparative analysis of the complete genome of an epidemic hospital sequence type 203 clone of vancomycin-resistant Enterococcus faecium.

Lam MM, Seemann T, Tobias NJ, Chen H, Haring V, Moore RJ, Ballard S, Grayson LM, Johnson PD, Howden BP, Stinear TP.

BMC Genomics. 2013 Sep 1;14:595. doi: 10.1186/1471-2164-14-595.


Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis.

Hui CL, Wong GH, Tang JY, Chang WC, Chan SK, Lee EH, Lam MM, Chiu CP, Law CW, Chung DW, Tso S, Pang EP, Chan KT, Wong YC, Mo FY, Chan KP, Hung SF, Honer WG, Chen EY.

Schizophr Res. 2013 Oct;150(1):297-302. doi: 10.1016/j.schres.2013.08.010. Epub 2013 Aug 29.


Genomic insights to control the emergence of vancomycin-resistant enterococci.

Howden BP, Holt KE, Lam MM, Seemann T, Ballard S, Coombs GW, Tong SY, Grayson ML, Johnson PD, Stinear TP.

MBio. 2013 Aug 13;4(4). pii: e00412-13. doi: 10.1128/mBio.00412-13.


Genomic analysis of teicoplanin resistance emerging during treatment of vanB vancomycin-resistant Enterococcus faecium infections in solid organ transplant recipients including donor-derived cases.

Holmes NE, Ballard SA, Lam MM, Johnson PD, Grayson ML, Stinear TP, Howden BP.

J Antimicrob Chemother. 2013 Sep;68(9):2134-9. doi: 10.1093/jac/dkt130. Epub 2013 Apr 23.


Three-year outcome of phase-specific early intervention for first-episode psychosis: a cohort study in Hong Kong.

Chen EY, Tang JY, Hui CL, Chan SK, Chang WC, Lee EH, Chiu CP, Lam MM, Law CW, Yew CW, Wong GH, Chung DW, Tso S, Chan KP, Yip KC, Fung SF, Honer WG.

Hong Kong Med J. 2012 Dec;18 Suppl 6:7-13. No abstract available.


Gut-associated biomarkers L-FABP, I-FABP, and TFF3 and LIT score for diagnosis of surgical necrotizing enterocolitis in preterm infants.

Ng EW, Poon TC, Lam HS, Cheung HM, Ma TP, Chan KY, Wong RP, Leung KT, Lam MM, Li K, Ng PC.

Ann Surg. 2013 Dec;258(6):1111-8. doi: 10.1097/SLA.0b013e318288ea96.


Liver steatosis: concordance of MR imaging and MR spectroscopic data with histologic grade.

Noworolski SM, Lam MM, Merriman RB, Ferrell L, Qayyum A.

Radiology. 2012 Jul;264(1):88-96. doi: 10.1148/radiol.12110673.


Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex.

Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, Rašin MR, Sousa AM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, Schwartz ML, Willemsen R, Oostra BA, Rakic P, Heffer M, Kostović I, Judaš M, Sestan N.

Cell. 2012 May 11;149(4):899-911. doi: 10.1016/j.cell.2012.02.060.


Duration of untreated psychosis: relationship with baseline characteristics and three-year outcome in first-episode psychosis.

Chang WC, Tang JY, Hui CL, Lam MM, Wong GH, Chan SK, Chiu CP, Chung DW, Law CW, Tso S, Chan K, Hung SF, Chen EY.

Psychiatry Res. 2012 Aug 15;198(3):360-5. doi: 10.1016/j.psychres.2011.09.006. Epub 2012 Mar 16.


Comparative analysis of the first complete Enterococcus faecium genome.

Lam MM, Seemann T, Bulach DM, Gladman SL, Chen H, Haring V, Moore RJ, Ballard S, Grayson ML, Johnson PD, Howden BP, Stinear TP.

J Bacteriol. 2012 May;194(9):2334-41. doi: 10.1128/JB.00259-12. Epub 2012 Feb 24.


Prediction of remission and recovery in young people presenting with first-episode psychosis in Hong Kong: a 3-year follow-up study.

Chang WC, Tang JY, Hui CL, Lam MM, Chan SK, Wong GH, Chiu CP, Chen EY.

Aust N Z J Psychiatry. 2012 Feb;46(2):100-8. doi: 10.1177/0004867411428015.


Clinical and cognitive correlates of insight in first-episode schizophrenia.

Chan SK, Chan KK, Lam MM, Chiu CP, Hui CL, Wong GH, Chang WC, Chen EY.

Schizophr Res. 2012 Mar;135(1-3):40-5. doi: 10.1016/j.schres.2011.12.013. Epub 2012 Jan 13.


Screening and assessing ideas and delusions of reference using a semi-structured interview scale: a validation study of the Ideas of Reference Interview Scale (IRIS) in early psychosis patients.

Wong GH, Hui CL, Tang JY, Chiu CP, Lam MM, Chan SK, Chang WC, Chen EY.

Schizophr Res. 2012 Mar;135(1-3):158-63. doi: 10.1016/j.schres.2011.12.006. Epub 2012 Jan 12.


Persistent negative symptoms in first-episode schizophrenia: a prospective three-year follow-up study.

Chang WC, Hui CL, Tang JY, Wong GH, Lam MM, Chan SK, Chen EY.

Schizophr Res. 2011 Dec;133(1-3):22-8. doi: 10.1016/j.schres.2011.09.006. Epub 2011 Oct 2.


Cost-effectiveness of an early assessment service for young people with early psychosis in Hong Kong.

Wong KK, Chan SK, Lam MM, Hui CL, Hung SF, Tay M, Lee KH, Chen EY.

Aust N Z J Psychiatry. 2011 Aug;45(8):673-80. doi: 10.3109/00048674.2011.586329.


SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.

Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stančáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, Farese RV Jr, Kahn CR, Verdin E.

Mol Cell. 2011 Oct 21;44(2):177-90. doi: 10.1016/j.molcel.2011.07.019.


Three-year outcome of phase-specific early intervention for first-episode psychosis: a cohort study in Hong Kong.

Chen EY, Tang JY, Hui CL, Chiu CP, Lam MM, Law CW, Yew CW, Wong GH, Chung DW, Tso S, Chan KP, Yip KC, Hung SF, Honer WG.

Early Interv Psychiatry. 2011 Nov;5(4):315-23. doi: 10.1111/j.1751-7893.2011.00279.x. Epub 2011 Jul 4.


Perceptions of relapse risks following first-episode psychosis and attitudes towards maintenance medication: a comparison between nursing and social work professionals.

Chan KK, Chin QP, Tang JY, Longenecker J, Hui CL, Chiu CP, Lam MM, Wong GH, Chen EY.

Early Interv Psychiatry. 2011 Nov;5(4):324-34. doi: 10.1111/j.1751-7893.2011.00268.x. Epub 2011 Apr 26.


Factors affecting mortality in Hong Kong patients with upper limb necrotising fasciitis.

Yeung YK, Ho ST, Yen CH, Ho PC, Tse WL, Lau YK, Choi KY, Choi ST, Lam MM, Cheng SH, Wong TC; Hong Kong Society for Surgery of the Hand.

Hong Kong Med J. 2011 Apr;17(2):96-104.


Random number generation deficit in early schizophrenia.

Chan KK, Hui CL, Tang JY, Chiu CP, Chan SK, Lam MM, Chen EY.

Percept Mot Skills. 2011 Feb;112(1):91-103.


TBR1 directly represses Fezf2 to control the laminar origin and development of the corticospinal tract.

Han W, Kwan KY, Shim S, Lam MM, Shin Y, Xu X, Zhu Y, Li M, Sestan N.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3041-6. doi: 10.1073/pnas.1016723108. Epub 2011 Feb 1.

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