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Covert COVID-19 and false-positive dengue serology in Singapore.

Yan G, Lee CK, Lam LTM, Yan B, Chua YX, Lim AYN, Phang KF, Kew GS, Teng H, Ngai CH, Lin L, Foo RM, Pada S, Ng LC, Tambyah PA.

Lancet Infect Dis. 2020 Mar 4. pii: S1473-3099(20)30158-4. doi: 10.1016/S1473-3099(20)30158-4. [Epub ahead of print] No abstract available.


Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.

Faivre EJ, McDaniel KF, Albert DH, Mantena SR, Plotnik JP, Wilcox D, Zhang L, Bui MH, Sheppard GS, Wang L, Sehgal V, Lin X, Huang X, Lu X, Uziel T, Hessler P, Lam LT, Bellin RJ, Mehta G, Fidanze S, Pratt JK, Liu D, Hasvold LA, Sun C, Panchal SC, Nicolette JJ, Fossey SL, Park CH, Longenecker K, Bigelow L, Torrent M, Rosenberg SH, Kati WM, Shen Y.

Nature. 2020 Feb;578(7794):306-310. doi: 10.1038/s41586-020-1930-8. Epub 2020 Jan 22.


Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

Holt I, Fuller HR, Lam LT, Sewry CA, Shirran SL, Zhang Q, Shanahan CM, Morris GE.

Sci Rep. 2019 Oct 2;9(1):14202. doi: 10.1038/s41598-019-50728-6.


Basic Psychological Needs Satisfaction and Frustration, Stress, and Sports Injury Among University Athletes: A Four-Wave Prospective Survey.

Li C, Ivarsson A, Lam LT, Sun J.

Front Psychol. 2019 Mar 26;10:665. doi: 10.3389/fpsyg.2019.00665. eCollection 2019.


Graded Exercise Testing Predicts Recovery Trajectory of Concussion in Children and Adolescents.

Orr R, Bogg T, Fyffe A, Lam LT, Browne GJ.

Clin J Sport Med. 2018 Nov 14. doi: 10.1097/JSM.0000000000000683. [Epub ahead of print]


Two alternatively-spliced human nebulin isoforms with either exon 143 or exon 144 and their developmental regulation.

Lam LT, Holt I, Laitila J, Hanif M, Pelin K, Wallgren-Pettersson C, Sewry CA, Morris GE.

Sci Rep. 2018 Oct 24;8(1):15728. doi: 10.1038/s41598-018-33281-6.


Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP.

Wang R, He Y, Robinson V, Yang Z, Hessler P, Lasko LM, Lu X, Bhathena A, Lai A, Uziel T, Lam LT.

Mol Cancer Ther. 2018 Dec;17(12):2543-2550. doi: 10.1158/1535-7163.MCT-18-0511. Epub 2018 Sep 28.


Predictors of mental health literacy in older people.

Piper SE, Bailey PE, Lam LT, Kneebone II.

Arch Gerontol Geriatr. 2018 Nov - Dec;79:52-56. doi: 10.1016/j.archger.2018.07.010. Epub 2018 Jul 26.


Application of the Social Network Analysis to Better Comprehend Relationships in Qualitative Health Data.

Lam LT, Lam MK, Benrimoj CS, Cardens VG.

Stud Health Technol Inform. 2018;252:86-91.


Statins enhance efficacy of venetoclax in blood cancers.

Lee JS, Roberts A, Juarez D, Vo TT, Bhatt S, Herzog LO, Mallya S, Bellin RJ, Agarwal SK, Salem AH, Xu T, Jia J, Li L, Hanna JR, Davids MS, Fleischman AG, O'Brien S, Lam LT, Leverson JD, Letai A, Schatz JH, Fruman DA.

Sci Transl Med. 2018 Jun 13;10(445). pii: eaaq1240. doi: 10.1126/scitranslmed.aaq1240.


Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Kluge AF, Patane MA, Van Drie JH, Wang C, McElligott D, Kesicki EA, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2018 Jun;558(7710):E1. doi: 10.1038/s41586-018-0111-5.


The association between financial literacy and Problematic Internet Shopping in a multinational sample.

Lam LT, Lam MK.

Addict Behav Rep. 2017 Oct 18;6:123-127. doi: 10.1016/j.abrep.2017.10.002. eCollection 2017 Dec.


Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Erratum in: Nature. 2018 May 16;:.


Identification of novel resistance mechanisms to NAMPT inhibition via the de novo NAD+ biosynthesis pathway and NAMPT mutation.

Guo J, Lam LT, Longenecker KL, Bui MH, Idler KB, Glaser KB, Wilsbacher JL, Tse C, Pappano WN, Huang TH.

Biochem Biophys Res Commun. 2017 Sep 23;491(3):681-686. doi: 10.1016/j.bbrc.2017.07.143. Epub 2017 Jul 26.


Potential mechanisms of resistance to venetoclax and strategies to circumvent it.

Tahir SK, Smith ML, Hessler P, Rapp LR, Idler KB, Park CH, Leverson JD, Lam LT.

BMC Cancer. 2017 Jun 2;17(1):399. doi: 10.1186/s12885-017-3383-5.


Vulnerability of Small-Cell Lung Cancer to Apoptosis Induced by the Combination of BET Bromodomain Proteins and BCL2 Inhibitors.

Lam LT, Lin X, Faivre EJ, Yang Z, Huang X, Wilcox DM, Bellin RJ, Jin S, Tahir SK, Mitten M, Magoc T, Bhathena A, Kati WM, Albert DH, Shen Y, Uziel T.

Mol Cancer Ther. 2017 Aug;16(8):1511-1520. doi: 10.1158/1535-7163.MCT-16-0459. Epub 2017 May 3.


Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies.

Bui MH, Lin X, Albert DH, Li L, Lam LT, Faivre EJ, Warder SE, Huang X, Wilcox D, Donawho CK, Sheppard GS, Wang L, Fidanze S, Pratt JK, Liu D, Hasvold L, Uziel T, Lu X, Kohlhapp F, Fang G, Elmore SW, Rosenberg SH, McDaniel KF, Kati WM, Shen Y.

Cancer Res. 2017 Jun 1;77(11):2976-2989. doi: 10.1158/0008-5472.CAN-16-1793. Epub 2017 Apr 17.


Study protocol: a phase III randomised, double-blind, parallel arm, stratified, block randomised, placebo-controlled trial investigating the clinical effect and cost-effectiveness of sertraline for the palliative relief of breathlessness in people with chronic breathlessness.

Watts GJ, Clark K, Agar M, Davidson PM, McDonald C, Lam LT, Sajkov D, McCaffrey N, Doogue M, Abernethy AP, Currow DC; Australian national Palliative Care Clinical Studies Collaborative (PaCCSC).

BMJ Open. 2016 Nov 29;6(11):e013177. doi: 10.1136/bmjopen-2016-013177.


eHealth Intervention for Problematic Internet Use (PIU).

Lam LT, Lam MK.

Curr Psychiatry Rep. 2016 Dec;18(12):107. Review.


Identifying Factors That Predict Worse Constipation Symptoms in Palliative Care Patients: A Secondary Analysis.

Clark K, Lam LT, Talley NJ, Phillips JL, Currow DC.

J Palliat Med. 2017 May;20(5):528-532. doi: 10.1089/jpm.2016.0331. Epub 2016 Oct 18.


Assessing the Presence and Severity of Constipation with Plain Radiographs in Constipated Palliative Care Patients.

Clark K, Lam LT, Talley NJ, Quinn J, Blight A, Byfieldt N, Currow DC.

J Palliat Med. 2016 Jun;19(6):617-21. doi: 10.1089/jpm.2015.0451. Epub 2016 May 20.


Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199).

Phillips DC, Xiao Y, Lam LT, Litvinovich E, Roberts-Rapp L, Souers AJ, Leverson JD.

Blood Cancer J. 2016 Mar 11;6:e403. doi: 10.1038/bcj.2016.12. No abstract available.


A Mixed-Methods, Randomized, Controlled Feasibility Trial to Inform the Design of a Phase III Trial to Test the Effect of the Handheld Fan on Physical Activity and Carer Anxiety in Patients With Refractory Breathlessness.

Johnson MJ, Booth S, Currow DC, Lam LT, Phillips JL.

J Pain Symptom Manage. 2016 May;51(5):807-15. doi: 10.1016/j.jpainsymman.2015.11.026. Epub 2016 Feb 12.


Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199).

Phillips DC, Xiao Y, Lam LT, Litvinovich E, Roberts-Rapp L, Souers AJ, Leverson JD.

Blood Cancer J. 2015 Nov 13;5:e368. doi: 10.1038/bcj.2015.88. Erratum in: Blood Cancer J. 2016;6:e403.


Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer.

Zhang H, Xue J, Hessler P, Tahir SK, Chen J, Jin S, Souers AJ, Leverson JD, Lam LT.

Mol Cancer. 2015 Jul 2;14:126. doi: 10.1186/s12943-015-0397-y.


Stress moderates the relationship between problematic Internet use by parents and problematic Internet use by adolescents.

Lam LT, Wong EM.

J Adolesc Health. 2015 Mar;56(3):300-6. doi: 10.1016/j.jadohealth.2014.10.263.


Antihelminthic benzimidazoles potentiate navitoclax (ABT-263) activity by inducing Noxa-dependent apoptosis in non-small cell lung cancer (NSCLC) cell lines.

Lam LT, Zhang H, Xue J, Leverson JD, Bhathena A.

Cancer Cell Int. 2015 Feb 4;15(1):5. doi: 10.1186/s12935-014-0151-3. eCollection 2015.


Knowledge, attitudes, beliefs and behaviour intentions for three bowel management practices in intensive care: effects of a targeted protocol implementation for nursing and medical staff.

Knowles S, Lam LT, McInnes E, Elliott D, Hardy J, Middleton S.

BMC Nurs. 2015 Jan 31;14:6. doi: 10.1186/s12912-015-0056-z. eCollection 2015.


Parental mental health and Internet Addiction in adolescents.

Lam LT.

Addict Behav. 2015 Mar;42:20-3. doi: 10.1016/j.addbeh.2014.10.033. Epub 2014 Nov 1.


Orofacial functional impairments among patients following stroke: a systematic review.

Dai R, Lam OL, Lo EC, Li LS, Wen Y, McGrath C.

Oral Dis. 2015 Oct;21(7):836-49. doi: 10.1111/odi.12274. Epub 2014 Sep 12. Review.


The association between internet addiction and psychiatric co-morbidity: a meta-analysis.

Ho RC, Zhang MW, Tsang TY, Toh AH, Pan F, Lu Y, Cheng C, Yip PS, Lam LT, Lai CM, Watanabe H, Mak KK.

BMC Psychiatry. 2014 Jun 20;14:183. doi: 10.1186/1471-244X-14-183.


Multiplex analysis of anti-apoptotic BCL2 family and caspase 3 activation by microbead arrays.

Lam LT, Roberts-Rapp L.

Assay Drug Dev Technol. 2014 Apr;12(3):190-6. doi: 10.1089/adt.2013.557.


Internet gaming addiction, problematic use of the internet, and sleep problems: a systematic review.

Lam LT.

Curr Psychiatry Rep. 2014 Apr;16(4):444. doi: 10.1007/s11920-014-0444-1. Review.


Correlations between polysomnographic and lateral airway radiograph measurements in paediatric obstructive sleep apnoea.

Waters K, Kol-Castro C, Varghese A, Lam LT, Prelog K, Cheng A.

J Paediatr Child Health. 2013 Jun;49(6):445-51. doi: 10.1111/jpc.12212. Epub 2013 Apr 29.


ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.

Souers AJ, Leverson JD, Boghaert ER, Ackler SL, Catron ND, Chen J, Dayton BD, Ding H, Enschede SH, Fairbrother WJ, Huang DC, Hymowitz SG, Jin S, Khaw SL, Kovar PJ, Lam LT, Lee J, Maecker HL, Marsh KC, Mason KD, Mitten MJ, Nimmer PM, Oleksijew A, Park CH, Park CM, Phillips DC, Roberts AW, Sampath D, Seymour JF, Smith ML, Sullivan GM, Tahir SK, Tse C, Wendt MD, Xiao Y, Xue JC, Zhang H, Humerickhouse RA, Rosenberg SH, Elmore SW.

Nat Med. 2013 Feb;19(2):202-8. doi: 10.1038/nm.3048. Epub 2013 Jan 6.


Violent online games exposure and cyberbullying/victimization among adolescents.

Lam LT, Cheng Z, Liu X.

Cyberpsychol Behav Soc Netw. 2013 Mar;16(3):159-65. doi: 10.1089/cyber.2012.0087. Epub 2012 Dec 19.


Biomarkers of therapeutic response to BCL2 antagonists in cancer.

Lam LT, Zhang H, Chyla B.

Mol Diagn Ther. 2012 Dec;16(6):347-56. doi: 10.1007/s40291-012-0003-6. Review.


Factors associated with social interaction anxiety among Chinese adolescents.

Peng ZW, Lam LT, Jin J.

East Asian Arch Psychiatry. 2011 Dec;21(4):135-41.


The use of non-invasive ventilation for the relief of dyspnoea in exacerbations of chronic obstructive pulmonary disease; a systematic review.

Smith TA, Davidson PM, Lam LT, Jenkins CR, Ingham JM.

Respirology. 2012 Feb;17(2):300-7. doi: 10.1111/j.1440-1843.2011.02085.x. Review.


A randomised trial of a four-step multidisciplinary approach to the antenatal care of obese pregnant women.

Quinlivan JA, Lam LT, Fisher J.

Aust N Z J Obstet Gynaecol. 2011 Apr;51(2):141-6. doi: 10.1111/j.1479-828X.2010.01268.x. Epub 2011 Jan 31.


A mechanistic rationale for MEK inhibitor therapy in myeloma based on blockade of MAF oncogene expression.

Annunziata CM, Hernandez L, Davis RE, Zingone A, Lamy L, Lam LT, Hurt EM, Shaffer AL, Kuehl WM, Staudt LM.

Blood. 2011 Feb 24;117(8):2396-404. doi: 10.1182/blood-2010-04-278788. Epub 2010 Dec 16.


Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines.

Zhang H, Guttikonda S, Roberts L, Uziel T, Semizarov D, Elmore SW, Leverson JD, Lam LT.

Oncogene. 2011 Apr 21;30(16):1963-8. doi: 10.1038/onc.2010.559. Epub 2010 Dec 6.


The pulmonary index score as a clinical assessment tool for acute childhood asthma.

Hsu P, Lam LT, Browne G.

Ann Allergy Asthma Immunol. 2010 Dec;105(6):425-9. doi: 10.1016/j.anai.2010.10.009.


Does psychological distress increase the risk for motor vehicle crashes in young people? findings from the DRIVE study.

Martiniuk AL, Ivers RQ, Glozier N, Patton GC, Senserrick T, Boufous S, Lam LT, Williamson A, Stevenson M, Woodward M, Norton R.

J Adolesc Health. 2010 Nov;47(5):488-95. doi: 10.1016/j.jadohealth.2010.03.010. Epub 2010 May 21.


Selecting medical students for academic and attitudinal outcomes in a Catholic medical school.

Quinlivan JA, Lam LT, Wan Sh, Petersen RW.

Med J Aust. 2010 Sep 20;193(6):347-50.


A microRNA screen to identify modulators of sensitivity to BCL2 inhibitor ABT-263 (navitoclax).

Lam LT, Lu X, Zhang H, Lesniewski R, Rosenberg S, Semizarov D.

Mol Cancer Ther. 2010 Nov;9(11):2943-50. doi: 10.1158/1535-7163.MCT-10-0427. Epub 2010 Sep 9.


Effect of pathological use of the internet on adolescent mental health: a prospective study.

Lam LT, Peng ZW.

Arch Pediatr Adolesc Med. 2010 Oct;164(10):901-6. doi: 10.1001/archpediatrics.2010.159.


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