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Novel redox-responsive polymeric magnetosomes with tunable magnetic resonance property for in vivo drug release visualization and dual-modal cancer therapy.

Wang Z, Xue X, He Y, Lu Z, Jia B, Wu H, Yuan Y, Huang Y, Wang H, Lu H, Lam KS, Lin TY, Li Y.

Adv Funct Mater. 2018 Aug 15;28(33). pii: 1802159. doi: 10.1002/adfm.201802159. Epub 2018 Jun 22.


High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer.

Xiao W, Ma W, Wei S, Li Q, Liu R, Carney RP, Yang K, Lee J, Nyugen A, Yoneda KY, Lam KS, Li T.

J Hematol Oncol. 2019 Jun 10;12(1):56. doi: 10.1186/s13045-019-0740-7.


Galectin-1 Inhibition Induces Cell Apoptosis Through Dual Suppression of CXCR4 and Ras Pathways in Human Malignant Peripheral Nerve Sheath Tumors.

Shih TC, Fan Y, Kiss S, Li X, Deng XN, Liu R, Chen XJ, Carney R, Chen A, Ghosh PM, Lam KS.

Neuro Oncol. 2019 May 24. pii: noz093. doi: 10.1093/neuonc/noz093. [Epub ahead of print]


Rapid Discovery of Illuminating Peptides for Instant Detection of Opioids in Blood and Body Fluids.

Jafari S, Thillier Y, Ajena YH, Shorty D, Li J, Huynh JS, Pan BM, Pan T, Lam KS, Liu R.

Molecules. 2019 May 10;24(9). pii: E1813. doi: 10.3390/molecules24091813.


Daunorubicin-containing CLL1-targeting nanomicelles have anti-leukemia stem cell activity in acute myeloid leukemia.

Lin TY, Zhu Y, Li Y, Zhang H, Ma AH, Long Q, Keck J, Lam KS, Pan CX, Jonas BA.

Nanomedicine. 2019 May 2;20:102004. doi: 10.1016/j.nano.2019.04.007. [Epub ahead of print]


Glycogenic hepatopathy as an unusual etiology of deranged liver function in a patient with type 1 diabetes: A case report.

Lui DT, Woo YC, Chow WS, Lee CH, Lee AC, Leung EK, Tan KC, Lam KS, Lam JK.

Medicine (Baltimore). 2019 Apr;98(17):e15296. doi: 10.1097/MD.0000000000015296.


Dual blockage of STAT3 and ERK1/2 eliminates radioresistant GBM cells.

Xie B, Zhang L, Hu W, Fan M, Jiang N, Duan Y, Jing D, Xiao W, Fragoso RC, Lam KS, Sun LQ, Li JJ.

Redox Biol. 2019 Jun;24:101189. doi: 10.1016/j.redox.2019.101189. Epub 2019 Apr 9.


Association of adipokines with hepatic steatosis and fibrosis in chronic hepatitis B patients on long-term nucleoside analogue.

Mak LY, Lee CH, Cheung KS, Wong DK, Liu F, Hui RW, Fung J, Xu A, Lam KS, Yuen MF, Seto WK.

Liver Int. 2019 Jul;39(7):1217-1225. doi: 10.1111/liv.14104. Epub 2019 Apr 11.


Affinity selection and sequencing.

Lam KS.

Nat Chem Biol. 2019 Apr;15(4):320-321. doi: 10.1038/s41589-019-0253-2. No abstract available.


Alternative Splicing of MXD3 and Its Regulation of MXD3 Levels in Glioblastoma.

Ngo T, Corrales A, Bourne T, Elmojahid S, Lam KS, Díaz E.

Front Mol Biosci. 2019 Feb 19;6:5. doi: 10.3389/fmolb.2019.00005. eCollection 2019.


Vedolizumab-mediated integrin α4β7 blockade does not control HIV-1SF162 rebound after combination antiretroviral therapy interruption in humanized mice.

Ling L, Wu T, To KKW, Cheung KW, Lui KOL, Niu M, Lam KS, Wang CC, Li J, Wang H, Yuen KY, Chen Z.

AIDS. 2019 Mar 15;33(4):F1-F12. doi: 10.1097/QAD.0000000000002149.


Novel window for cancer nanotheranostics: non-invasive ocular assessments of tumor growth and nanotherapeutic treatment efficacy in vivo.

Goswami M, Wang X, Zhang P, Xiao W, Karlen SJ, Li Y, Zawadzki RJ, Burns ME, Lam KS, Pugh EN Jr.

Biomed Opt Express. 2018 Dec 11;10(1):151-166. doi: 10.1364/BOE.10.000151. eCollection 2019 Jan 1.


Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes.

Kumar P, Becker JC, Gao K, Carney RP, Lankford L, Keller BA, Herout K, Lam KS, Farmer DL, Wang A.

FASEB J. 2019 May;33(5):5836-5849. doi: 10.1096/fj.201800972R. Epub 2019 Feb 12.


Never too old for statin treatment?

Cheung BMY, Lam KSL.

Lancet. 2019 Feb 2;393(10170):379-380. doi: 10.1016/S0140-6736(18)32263-3. No abstract available.


Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation.

Pan Y, Hui X, Hoo RLC, Ye D, Chan CYC, Feng T, Wang Y, Lam KSL, Xu A.

J Clin Invest. 2019 Feb 1;129(2):834-849. doi: 10.1172/JCI123069. Epub 2019 Jan 22.


Vedolizumab-mediated integrin α4β7 blockade does not control HIV-1SF162 rebound after cART interruption in humanized mice.

Ling L, Wu T, To KKW, Cheung KW, Lui KO, Niu M, Lam KS, Wang CC, Li J, Wang H, Yuen KY, Chen Z.

AIDS. 2019 Jan 14. doi: 10.1097/QAD.0000000000002149. [Epub ahead of print]


Alginate Hydrogel Modified with a Ligand Interacting with α3β1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro.

Wen H, Xiao W, Biswas S, Cong ZQ, Liu XM, Lam KS, Liao YH, Deng W.

ACS Appl Mater Interfaces. 2019 Feb 13;11(6):5821-5833. doi: 10.1021/acsami.8b19438. Epub 2019 Jan 29.


Combinatorial Peptide Microarray Synthesis Based on Microfluidic Impact Printing.

Li J, Zhao S, Yang G, Liu R, Xiao W, Disano P, Lam KS, Pan T.

ACS Comb Sci. 2019 Jan 14;21(1):6-10. doi: 10.1021/acscombsci.8b00125. Epub 2018 Dec 30.


Erratum. Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans. Diabetes 2008;57:1246-1253.

Zhang X, Yeung DCY, Karpisek M, Stejskal D, Zhou ZG, Liu F, Wong RLC, Chow WS, Tso AWK, Lam KSL, Xu A.

Diabetes. 2019 Jan;68(1):235. doi: 10.2337/db19-er01c. Epub 2018 Nov 19. No abstract available.


Fighting the Health Challenges of Diabetes in Hong Kong: A Window Into Mainland China.

Lee PCH, Woo YC, Lam KSL.

Am J Public Health. 2018 Dec;108(12):1623-1624. doi: 10.2105/AJPH.2018.304740. No abstract available.


Dietary Intake of Anti-Oxidant Vitamins A, C, and E Is Inversely Associated with Adverse Cardiovascular Outcomes in Chinese-A 22-Years Population-Based Prospective Study.

Lee CH, Chan RSM, Wan HYL, Woo YC, Cheung CYY, Fong CHY, Cheung BMY, Lam TH, Janus E, Woo J, Lam KSL.

Nutrients. 2018 Nov 4;10(11). pii: E1664. doi: 10.3390/nu10111664.


A Plug-and-Play, Drug-on-Pillar Platform for Combination Drug Screening Implemented by Microfluidic Adaptive Printing.

Li J, Tan W, Xiao W, Carney RP, Men Y, Li Y, Quon G, Ajena Y, Lam KS, Pan T.

Anal Chem. 2018 Dec 4;90(23):13969-13977. doi: 10.1021/acs.analchem.8b03456. Epub 2018 Nov 13.


Age-Biomarkers-Clinical Risk Factors for Prediction of Cardiovascular Events in Patients With Coronary Artery Disease.

Wong YK, Cheung CYY, Tang CS, Au KW, Hai JSH, Lee CH, Lau KK, Cheung BMY, Sham PC, Xu A, Lam KSL, Tse HF.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2519-2527. doi: 10.1161/ATVBAHA.118.311726.


Unique Photochemo-Immuno-Nanoplatform against Orthotopic Xenograft Oral Cancer and Metastatic Syngeneic Breast Cancer.

Zhang L, Jing D, Wang L, Sun Y, Li JJ, Hill B, Yang F, Li Y, Lam KS.

Nano Lett. 2018 Nov 14;18(11):7092-7103. doi: 10.1021/acs.nanolett.8b03096. Epub 2018 Oct 26.


Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes.

Cheung CYY, Lee CH, Tang CS, Xu A, Au KW, Fong CHY, Ng KKK, Kwok KHM, Chow WS, Woo YC, Yuen MMA, Hai J, Tan KCB, Lam TH, Tse HF, Sham PC, Lam KSL.

Diabetes. 2019 Jan;68(1):198-206. doi: 10.2337/db18-0500. Epub 2018 Oct 10.


Prospective associations of circulating adipocyte fatty acid-binding protein levels with risks of renal outcomes and mortality in type 2 diabetes.

Lee CH, Cheung CYY, Woo YC, Lui DTW, Yuen MMA, Fong CHY, Chow WS, Xu A, Lam KSL.

Diabetologia. 2019 Jan;62(1):169-177. doi: 10.1007/s00125-018-4742-8. Epub 2018 Sep 28.


Corrigendum to "A Phase I, Single- and Multiple-dose Study to Evaluate the Pharmacokinetics of Elbasvir and Grazoprevir in Healthy Chinese Participants" [Clinical Therapeutics 40 (2018) 719-732].

Cheung TT, Chiu JWY, Yuen MF, Lam KSL, Cheung BMY, Feng HP, Yeh WW, Wang J, Li W, Zhao XM, Wang Z, Mu S.

Clin Ther. 2018 Sep;40(9):1618. doi: 10.1016/j.clinthera.2018.06.005. Epub 2018 Aug 25. No abstract available.


Obesity-induced insulin resistance and macrophage infiltration of the adipose tissue: A vicious cycle.

Lee CH, Lam KS.

J Diabetes Investig. 2019 Jan;10(1):29-31. doi: 10.1111/jdi.12918. Epub 2018 Sep 24. No abstract available.


Identification of integrin drug targets for 17 solid tumor types.

Arun AS, Tepper CG, Lam KS.

Oncotarget. 2018 Jul 10;9(53):30146-30162. doi: 10.18632/oncotarget.25731. eCollection 2018 Jul 10.


Circulating Adipocyte Fatty Acid-Binding Protein Concentrations Predict Multiple Mortality Outcomes among Men and Women with Diabetes.

Lee CH, Cheung CYY, Woo YC, Lui DTW, Yuen MMA, Fong CHY, Chow WS, Xu A, Lam KSL.

Clin Chem. 2018 Oct;64(10):1496-1504. doi: 10.1373/clinchem.2018.289157. Epub 2018 Jul 18.


Independent association of serum vitamin D with anti-Mullerian hormone levels in women with polycystic ovary syndrome.

Wong HYQ, Li HWR, Lam KSL, Tam S, Shek CC, Lee CYV, Yeung WSB, Ho PC, Ng EHY.

Clin Endocrinol (Oxf). 2018 Nov;89(5):634-641. doi: 10.1111/cen.13816. Epub 2018 Aug 7.


Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides.

Carney RP, Hazari S, Rojalin T, Knudson A, Gao T, Tang Y, Liu R, Viitala T, Yliperttula M, Lam KS.

Adv Biosyst. 2017 May;1(5). pii: 1600038. doi: 10.1002/adbi.201600038. Epub 2017 Apr 3.


Nanoformulated paclitaxel and AZD9291 synergistically eradicate non-small-cell lung cancers in vivo.

Wang XS, Zhang L, Li X, Kong DJ, Hu XC, Ding XZ, Yang JQ, Zhao MQ, He Y, Lam KS, Gao SG, Lin TY, Li Y.

Nanomedicine (Lond). 2018 May;13(10):1107-1120. doi: 10.2217/nnm-2017-0355. Epub 2018 Jun 6.


Reversibly disulfide cross-linked micelles improve the pharmacokinetics and facilitate the targeted, on-demand delivery of doxorubicin in the treatment of B-cell lymphoma.

Xiao K, Liu Q, Al Awwad N, Zhang H, Lai L, Luo Y, Lee JS, Li Y, Lam KS.

Nanoscale. 2018 May 3;10(17):8207-8216. doi: 10.1039/c8nr00680f.


Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion.

Shih TC, Liu R, Wu CT, Li X, Xiao W, Deng X, Kiss S, Wang T, Chen XJ, Carney R, Kung HJ, Duan Y, Ghosh PM, Lam KS.

Clin Cancer Res. 2018 Sep 1;24(17):4319-4331. doi: 10.1158/1078-0432.CCR-18-0157. Epub 2018 Apr 17.


Size-Modulable Nanoprobe for High-Performance Ultrasound Imaging and Drug Delivery against Cancer.

Zhang L, Yin T, Li B, Zheng R, Qiu C, Lam KS, Zhang Q, Shuai X.

ACS Nano. 2018 Apr 24;12(4):3449-3460. doi: 10.1021/acsnano.8b00076. Epub 2018 Apr 13.


Microfluidic Print-to-Synthesis Platform for Efficient Preparation and Screening of Combinatorial Peptide Microarrays.

Li J, Carney RP, Liu R, Fan J, Zhao S, Chen Y, Lam KS, Pan T.

Anal Chem. 2018 May 1;90(9):5833-5840. doi: 10.1021/acs.analchem.8b00371. Epub 2018 Apr 13.


Corrigendum to 'Tumor-targeting peptides from combinatorial libraries' [Adv Drug Deliv Rev.110-111 (2017) 13-37].

Liu R, Li X, Xiao W, Lam KS.

Adv Drug Deliv Rev. 2018 Feb 1;125:152. doi: 10.1016/j.addr.2018.02.005. Epub 2018 Mar 9. No abstract available.


Tandem bispecific neutralizing antibody eliminates HIV-1 infection in humanized mice.

Wu X, Guo J, Niu M, An M, Liu L, Wang H, Jin X, Zhang Q, Lam KS, Wu T, Wang H, Wang Q, Du Y, Li J, Cheng L, Tang HY, Shang H, Zhang L, Zhou P, Chen Z.

J Clin Invest. 2018 Jun 1;128(6):2239-2251. doi: 10.1172/JCI96764. Epub 2018 Apr 23.


Reply to Letter to the Editor.

Lam KS.

Curr Opin Chem Biol. 2018 Feb;42:187. doi: 10.1016/j.cbpa.2018.01.011. Epub 2018 Feb 14. No abstract available.


Transient activation of Wnt/β-catenin signaling reporter in fibrotic scar formation after compression spinal cord injury in adult mice.

Yamagami T, Pleasure DE, Lam KS, Zhou CJ.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1302-1307. doi: 10.1016/j.bbrc.2018.02.004. Epub 2018 Feb 3.


Dystrophic Scoliosis in Neurofibromatosis and Rib-head Resection: A Case Report.

Chong KL, Lam KS, Zuki Z.

Malays Orthop J. 2017 Nov;11(3):59-62. doi: 10.5704/MOJ.1711.007.


Dapagliflozin and Empagliflozin Ameliorate Hepatic Dysfunction Among Chinese Subjects with Diabetes in Part Through Glycemic Improvement: A Single-Center, Retrospective, Observational Study.

Lee PCH, Gu Y, Yeung MY, Fong CHY, Woo YC, Chow WS, Tan K, Lam KSL.

Diabetes Ther. 2018 Feb;9(1):285-295. doi: 10.1007/s13300-017-0355-3. Epub 2018 Jan 10.


Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model.

Long Q, Lin TY, Huang Y, Li X, Ma AH, Zhang H, Carney R, Airhart S, Lam KS, deVere White RW, Pan CX, Li Y.

Nanomedicine. 2018 Apr;14(3):789-799. doi: 10.1016/j.nano.2017.12.014. Epub 2018 Jan 6.


Simple and Rapid Tissue Clearing Method for Three-Dimensional Histology of the Pancreas.

Wong HS, Yeung PKK, Lai HM, Lam KSL, Wutian W, Chung SK.

Curr Protoc Cell Biol. 2017 Dec 11;77:19.20.1-19.20.10. doi: 10.1002/cpcb.34.


Genetically deprived vitamin D exposure predisposes to atrial fibrillation.

Chan YH, Yiu KH, Hai JJ, Chan PH, Lam TH, Cowling BJ, Sham PC, Lau CP, Lam KS, Siu CW, Tse HF.

Europace. 2017 Dec 1;19(suppl_4):iv25-iv31. doi: 10.1093/europace/eux312.


"One-Pot" Fabrication of Highly Versatile and Biocompatible Poly(vinyl alcohol)-porphyrin-based Nanotheranostics.

Luo Y, Wu H, Feng C, Xiao K, Yang X, Liu Q, Lin TY, Zhang H, Walton JH, Ajena Y, Hu Y, Lam KS, Li Y.

Theranostics. 2017 Sep 5;7(16):3901-3914. doi: 10.7150/thno.20190. eCollection 2017.


Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Lu X, Peloso GM, Liu DJ, Wu Y, Zhang H, Zhou W, Li J, Tang CS, Dorajoo R, Li H, Long J, Guo X, Xu M, Spracklen CN, Chen Y, Liu X, Zhang Y, Khor CC, Liu J, Sun L, Wang L, Gao YT, Hu Y, Yu K, Wang Y, Cheung CYY, Wang F, Huang J, Fan Q, Cai Q, Chen S, Shi J, Yang X, Zhao W, Sheu WH, Cherny SS, He M, Feranil AB, Adair LS, Gordon-Larsen P, Du S, Varma R, Chen YI, Shu XO, Lam KSL, Wong TY, Ganesh SK, Mo Z, Hveem K, Fritsche LG, Nielsen JB, Tse HF, Huo Y, Cheng CY, Chen YE, Zheng W, Tai ES, Gao W, Lin X, Huang W, Abecasis G; GLGC Consortium, Kathiresan S, Mohlke KL, Wu T, Sham PC, Gu D, Willer CJ.

Nat Genet. 2017 Dec;49(12):1722-1730. doi: 10.1038/ng.3978. Epub 2017 Oct 30.


Validation of the diabetes screening tools proposed by the American Diabetes Association in an aging Chinese population.

Woo YC, Lee CH, Fong CHY, Tso AWK, Cheung BMY, Lam KSL.

PLoS One. 2017 Sep 14;12(9):e0184840. doi: 10.1371/journal.pone.0184840. eCollection 2017.


Extremely long tumor retention, multi-responsive boronate crosslinked micelles with superior therapeutic efficacy for ovarian cancer.

Xiao W, Suby N, Xiao K, Lin TY, Al Awwad N, Lam KS, Li Y.

J Control Release. 2017 Oct 28;264:169-179. doi: 10.1016/j.jconrel.2017.08.028. Epub 2017 Aug 25.

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