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Phase II Trial of Acai Juice Product in Biochemically Recurrent Prostate Cancer.

Kessler ER, Su LJ, Gao D, Torkko KC, Wacker M, Anduha M, Chronister N, Maroni P, Crawford ED, Flaig TW, Glode LM, Lam ET.

Integr Cancer Ther. 2018 Dec;17(4):1103-1108. doi: 10.1177/1534735418803755. Epub 2018 Oct 5.


High-resolution comparative analysis of great ape genomes.

Kronenberg ZN, Fiddes IT, Gordon D, Murali S, Cantsilieris S, Meyerson OS, Underwood JG, Nelson BJ, Chaisson MJP, Dougherty ML, Munson KM, Hastie AR, Diekhans M, Hormozdiari F, Lorusso N, Hoekzema K, Qiu R, Clark K, Raja A, Welch AE, Sorensen M, Baker C, Fulton RS, Armstrong J, Graves-Lindsay TA, Denli AM, Hoppe ER, Hsieh P, Hill CM, Pang AWC, Lee J, Lam ET, Dutcher SK, Gage FH, Warren WC, Shendure J, Haussler D, Schneider VA, Cao H, Ventura M, Wilson RK, Paten B, Pollen A, Eichler EE.

Science. 2018 Jun 8;360(6393). pii: eaar6343. doi: 10.1126/science.aar6343.


Renal cell carcinoma: a review of biology and pathophysiology.

Nabi S, Kessler ER, Bernard B, Flaig TW, Lam ET.

F1000Res. 2018 Mar 12;7:307. doi: 10.12688/f1000research.13179.1. eCollection 2018. Review.


Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma.

Courtney KD, Infante JR, Lam ET, Figlin RA, Rini BI, Brugarolas J, Zojwalla NJ, Lowe AM, Wang K, Wallace EM, Josey JA, Choueiri TK.

J Clin Oncol. 2018 Mar 20;36(9):867-874. doi: 10.1200/JCO.2017.74.2627. Epub 2017 Dec 19.


OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps.

Li L, Leung AK, Kwok TP, Lai YYY, Pang IK, Chung GT, Mak ACY, Poon A, Chu C, Li M, Wu JJK, Lam ET, Cao H, Lin C, Sibert J, Yiu SM, Xiao M, Lo KW, Kwok PY, Chan TF, Yip KY.

Genome Biol. 2017 Dec 1;18(1):230. doi: 10.1186/s13059-017-1356-2.


Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors.

Lam ET, Eckhardt SG, Messersmith W, Jimeno A, O'Bryant CL, Ramanathan RK, Weiss GJ, Chadha M, Oey A, Ding HT, Culp PA, Keller SF, Zhao VY, Tsao LC, Singhal A, Holen KD, Von Hoff D.

Mol Cancer Ther. 2018 Jan;17(1):215-221. doi: 10.1158/1535-7163.MCT-17-0330. Epub 2017 Oct 20.


Kidney Cancer, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.

Motzer RJ, Jonasch E, Agarwal N, Bhayani S, Bro WP, Chang SS, Choueiri TK, Costello BA, Derweesh IH, Fishman M, Gallagher TH, Gore JL, Hancock SL, Harrison MR, Kim W, Kyriakopoulos C, LaGrange C, Lam ET, Lau C, Michaelson MD, Olencki T, Pierorazio PM, Plimack ER, Redman BG, Shuch B, Somer B, Sonpavde G, Sosman J, Dwyer M, Kumar R.

J Natl Compr Canc Netw. 2017 Jun;15(6):804-834. doi: 10.6004/jnccn.2017.0100.


Phase II study of cabazitaxel with or without abiraterone acetate and prednisone in patients with metastatic castrate resistant prostate cancer after prior docetaxel and abiraterone acetate.

Kessler ER, Gao D, Flaig TW, Breaker K, Wold M, Wacker M, Lam ET.

Ann Oncol. 2017 Mar 1;28(3):668. doi: 10.1093/annonc/mdw674. No abstract available.


Impact of back squat training intensity on strength and flexibility of hamstring muscle group.

Shariat A, Lam ETC, Shaw BS, Shaw I, Kargarfard M, Sangelaji B.

J Back Musculoskelet Rehabil. 2017;30(3):641-647. doi: 10.3233/BMR-160526.


The application of a feasible exercise training program in the office setting.

Shariat A, Lam ET, Kargarfard M, Tamrin SB, Danaee M.

Work. 2017;56(3):421-428. doi: 10.3233/WOR-172508.


Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome.

Bickhart DM, Rosen BD, Koren S, Sayre BL, Hastie AR, Chan S, Lee J, Lam ET, Liachko I, Sullivan ST, Burton JN, Huson HJ, Nystrom JC, Kelley CM, Hutchison JL, Zhou Y, Sun J, Crisà A, Ponce de León FA, Schwartz JC, Hammond JA, Waldbieser GC, Schroeder SG, Liu GE, Dunham MJ, Shendure J, Sonstegard TS, Phillippy AM, Van Tassell CP, Smith TP.

Nat Genet. 2017 Apr;49(4):643-650. doi: 10.1038/ng.3802. Epub 2017 Mar 6.


Patient characterization and usage trends of proton beam therapy for localized prostate cancer in the United States: A study of the National Cancer Database.

Amini A, Raben D, Crawford ED, Flaig TW, Kessler ER, Lam ET, Maroni P, Pugh TJ.

Urol Oncol. 2017 Jun;35(6):438-446. doi: 10.1016/j.urolonc.2017.01.013. Epub 2017 Feb 15.


Prevalence of Anemia in Subjects Randomized into Roux-en-Y Gastric Bypass or Sleeve Gastrectomy.

Kheniser KG, Kashyap SR, Schauer PR, Lam ETC, Kullman ES.

Obes Surg. 2017 May;27(5):1381-1386. doi: 10.1007/s11695-017-2573-1.


Clinical significance of sunitinib-associated macrocytosis in metastatic renal cell carcinoma.

Bourlon MT, Gao D, Trigero S, Clemons JE, Breaker K, Lam ET, Flaig TW.

Cancer Med. 2016 Dec;5(12):3386-3393. doi: 10.1002/cam4.919. Epub 2016 Oct 19.


Effects of endurance and high intensity training on ICAM-1 and VCAM-1 levels and arterial pressure in obese and normal weight adolescents.

Kargarfard M, Lam ET, Shariat A, Asle Mohammadi M, Afrasiabi S, Shaw I, Shaw BS.

Phys Sportsmed. 2016 Sep;44(3):208-16. doi: 10.1080/00913847.2016.1200442. Epub 2016 Jul 5.


Physiological responses and exercise preference between the Trikke and the bicycle ergometer.

Lam ETC, Sparks K, Barton-Verdi MA, Lowe A, Jones D, Lam EC.

J Exerc Sci Fit. 2016 Jun;14(1):7-13. doi: 10.1016/j.jesf.2016.01.001. Epub 2016 Apr 23.


A hybrid approach for de novo human genome sequence assembly and phasing.

Mostovoy Y, Levy-Sakin M, Lam J, Lam ET, Hastie AR, Marks P, Lee J, Chu C, Lin C, Džakula Ž, Cao H, Schlebusch SA, Giorda K, Schnall-Levin M, Wall JD, Kwok PY.

Nat Methods. 2016 Jul;13(7):587-90. doi: 10.1038/nmeth.3865. Epub 2016 May 9.


Genome assembly and geospatial phylogenomics of the bed bug Cimex lectularius.

Rosenfeld JA, Reeves D, Brugler MR, Narechania A, Simon S, Durrett R, Foox J, Shianna K, Schatz MC, Gandara J, Afshinnekoo E, Lam ET, Hastie AR, Chan S, Cao H, Saghbini M, Kentsis A, Planet PJ, Kholodovych V, Tessler M, Baker R, DeSalle R, Sorkin LN, Kolokotronis SO, Siddall ME, Amato G, Mason CE.

Nat Commun. 2016 Feb 2;7:10164. doi: 10.1038/ncomms10164.


Upfront Chemotherapy for Metastatic Prostate Cancer.

Lam ET, Flaig TW.

Oncology (Williston Park). 2015 Dec;29(12):956-62. Review.


A Patient With Newly Diagnosed Metastatic Type 2 Papillary Renal Cell Carcinoma.

Bourlon MT, Meneses-Medina M, Vázquez-Manjarrez S, Bustamante-Romero FM, Gallegos-Garza AC, Lam ET.

Oncology (Williston Park). 2015 Nov;29(11):880-6. No abstract available.


Genome-Wide Structural Variation Detection by Genome Mapping on Nanochannel Arrays.

Mak AC, Lai YY, Lam ET, Kwok TP, Leung AK, Poon A, Mostovoy Y, Hastie AR, Stedman W, Anantharaman T, Andrews W, Zhou X, Pang AW, Dai H, Chu C, Lin C, Wu JJ, Li CM, Li JW, Yim AK, Chan S, Sibert J, Džakula Ž, Cao H, Yiu SM, Chan TF, Yip KY, Xiao M, Kwok PY.

Genetics. 2016 Jan;202(1):351-62. doi: 10.1534/genetics.115.183483. Epub 2015 Oct 28.


Local Control Rates of Metastatic Renal Cell Carcinoma (RCC) to Thoracic, Abdominal, and Soft Tissue Lesions Using Stereotactic Body Radiotherapy (SBRT).

Altoos B, Amini A, Yacoub M, Bourlon MT, Kessler EE, Flaig TW, Fisher CM, Kavanagh BD, Lam ET, Karam SD.

Radiat Oncol. 2015 Oct 28;10:218. doi: 10.1186/s13014-015-0528-z.


Does the Renal Parenchyma Adjacent to the Tumor Contribute to Kidney Function? A Critical Analysis of Glomerular Viability in Partial Nephrectomy Specimens.

Khemees TA, Lam ET, Joehlin-Price AS, Mortazavi A, Phillips GS, Shabsigh A, Sharp DS, Zynger DL.

Urology. 2016 Jan;87:114-9. doi: 10.1016/j.urology.2015.10.018. Epub 2015 Oct 23.


Tools and pipelines for BioNano data: molecule assembly pipeline and FASTA super scaffolding tool.

Shelton JM, Coleman MC, Herndon N, Lu N, Lam ET, Anantharaman T, Sheth P, Brown SJ.

BMC Genomics. 2015 Sep 29;16:734. doi: 10.1186/s12864-015-1911-8.


Efficacy of massage on muscle soreness, perceived recovery, physiological restoration and physical performance in male bodybuilders.

Kargarfard M, Lam ET, Shariat A, Shaw I, Shaw BS, Tamrin SB.

J Sports Sci. 2016;34(10):959-65. doi: 10.1080/02640414.2015.1081264. Epub 2015 Sep 3.


Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults.

Tranah GJ, Yaffe K, Katzman SM, Lam ET, Pawlikowska L, Kwok PY, Schork NJ, Manini TM, Kritchevsky S, Thomas F, Newman AB, Harris TB, Coleman AL, Gorin MB, Helzner EP, Rowbotham MC, Browner WS, Cummings SR; Health, Aging and Body Composition Study.

J Gerontol A Biol Sci Med Sci. 2015 Nov;70(11):1418-24. doi: 10.1093/gerona/glv097. Epub 2015 Aug 31.


Local control rates of metastatic renal cell carcinoma (RCC) to the bone using stereotactic body radiation therapy: Is RCC truly radioresistant?

Amini A, Altoos B, Bourlon MT, Bedrick E, Bhatia S, Kessler ER, Flaig TW, Fisher CM, Kavanagh BD, Lam ET, Karam SD.

Pract Radiat Oncol. 2015 Nov-Dec;5(6):e589-e596. doi: 10.1016/j.prro.2015.05.004. Epub 2015 Jun 30.


Testicular Cancer, Version 2.2015.

Motzer RJ, Jonasch E, Agarwal N, Beard C, Bhayani S, Bolger GB, Chang SS, Choueiri TK, Costello BA, Derweesh IH, Gupta S, Hancock SL, Kim JJ, Kuzel TM, Lam ET, Lau C, Levine EG, Lin DW, Michaelson MD, Olencki T, Pili R, Plimack ER, Rampersaud EN, Redman BG, Ryan CJ, Sheinfeld J, Shuch B, Sircar K, Somer B, Wilder RB, Dwyer M, Kumar R.

J Natl Compr Canc Netw. 2015 Jun;13(6):772-99.


Pharmacokinetic drug-drug interaction study of the angiopoietin-1/angiopoietin-2-inhibiting peptibody trebananib (AMG 386) and paclitaxel in patients with advanced solid tumors.

Diamond JR, Wu B, Agarwal N, Bowles DW, Lam ET, Werner TL, Rasmussen E, Gamelin E, Soto F, Friberg G, Sun YN, Sharma S.

Invest New Drugs. 2015 Jun;33(3):691-9. doi: 10.1007/s10637-015-0236-4. Epub 2015 Apr 21.


Assessing structural variation in a personal genome-towards a human reference diploid genome.

English AC, Salerno WJ, Hampton OA, Gonzaga-Jauregui C, Ambreth S, Ritter DI, Beck CR, Davis CF, Dahdouli M, Ma S, Carroll A, Veeraraghavan N, Bruestle J, Drees B, Hastie A, Lam ET, White S, Mishra P, Wang M, Han Y, Zhang F, Stankiewicz P, Wheeler DA, Reid JG, Muzny DM, Rogers J, Sabo A, Worley KC, Lupski JR, Boerwinkle E, Gibbs RA.

BMC Genomics. 2015 Apr 11;16:286. doi: 10.1186/s12864-015-1479-3.


SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer.

Yu EY, Li H, Higano CS, Agarwal N, Pal SK, Alva A, Heath EI, Lam ET, Gupta S, Lilly MB, Inoue Y, Chi KN, Vogelzang NJ, Quinn DI, Cheng HH, Plymate SR, Hussain M, Tangen CM, Thompson IM Jr.

J Clin Oncol. 2015 May 10;33(14):1601-8. doi: 10.1200/JCO.2014.59.4127. Epub 2015 Apr 6.


Kidney cancer, version 3.2015.

Motzer RJ, Jonasch E, Agarwal N, Beard C, Bhayani S, Bolger GB, Chang SS, Choueiri TK, Costello BA, Derweesh IH, Gupta S, Hancock SL, Kim JJ, Kuzel TM, Lam ET, Lau C, Levine EG, Lin DW, Michaelson MD, Olencki T, Pili R, Plimack ER, Rampersaud EN, Redman BG, Ryan CJ, Sheinfeld J, Shuch B, Sircar K, Somer B, Wilder RB, Dwyer M, Kumar R; National comprehensive cancer network.

J Natl Compr Canc Netw. 2015 Feb;13(2):151-9.


Rapid detection of structural variation in a human genome using nanochannel-based genome mapping technology.

Cao H, Hastie AR, Cao D, Lam ET, Sun Y, Huang H, Liu X, Lin L, Andrews W, Chan S, Huang S, Tong X, Requa M, Anantharaman T, Krogh A, Yang H, Cao H, Xu X.

Gigascience. 2014 Dec 30;3(1):34. doi: 10.1186/2047-217X-3-34. eCollection 2014.


Effects of polluted air on cardiovascular and hematological parameters after progressive maximal aerobic exercise.

Kargarfard M, Shariat A, Shaw BS, Shaw I, Lam ET, Kheiri A, Eatemadyboroujeni A, Tamrin SB.

Lung. 2015 Apr;193(2):275-81. doi: 10.1007/s00408-014-9679-1. Epub 2015 Jan 22.


Retrospective analysis of the safety and efficacy of high-dose interleukin-2 after prior tyrosine kinase inhibitor therapy in patients with advanced renal cell carcinoma.

Lam ET, Wong MK, Agarwal N, Redman BG, Logan T, Gao D, Flaig TW, Lewis K, Poust J, Monk P, Jarkowski A, Sendilnathan A, Bolden M, Kuzel TM, Olencki T.

J Immunother. 2014 Sep;37(7):360-5. doi: 10.1097/CJI.0000000000000044. Erratum in: J Immunother. 2014 Nov-Dec;37(9):468.


Application of next generation sequencing to CEPH cell lines to discover variants associated with FDA approved chemotherapeutics.

Hariani GD, Lam ET, Havener T, Kwok PY, McLeod HL, Wagner MJ, Motsinger-Reif AA.

BMC Res Notes. 2014 Jun 12;7:360. doi: 10.1186/1756-0500-7-360. Erratum in: BMC Res Notes. 2014;7:652. Lam, Ernest J [corrected to Lam, Ernest T].


Kidney cancer, version 2.2014.

Motzer RJ, Jonasch E, Agarwal N, Beard C, Bhayani S, Bolger GB, Chang SS, Choueiri TK, Derweesh IH, Gupta S, Hancock SL, Kim JJ, Kuzel TM, Lam ET, Lau C, Levine EG, Lin DW, Margolin KA, Michaelson MD, Olencki T, Pili R, Plimack ER, Rampersaud EN, Redman BG, Ryan CJ, Sheinfeld J, Sircar K, Somer B, Wang J, Wilder RB, Dwyer MA, Kumar R; Natiomal compresensive cancer networks.

J Natl Compr Canc Netw. 2014 Feb;12(2):175-82.


Phase I study of oral rigosertib (ON 01910.Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignancies.

Bowles DW, Diamond JR, Lam ET, Weekes CD, Astling DP, Anderson RT, Leong S, Gore L, Varella-Garcia M, Vogler BW, Keysar SB, Freas E, Aisner DL, Ren C, Tan AC, Wilhelm F, Maniar M, Eckhardt SG, Messersmith WA, Jimeno A.

Clin Cancer Res. 2014 Mar 15;20(6):1656-65. doi: 10.1158/1078-0432.CCR-13-2506. Epub 2014 Feb 3.


Collision renal cell papillary and medullary carcinoma in a 66-year-old man.

Lam ET, Kessler ER, Flaig TW, La Rosa FG.

Oncology (Williston Park). 2013 Sep;27(9):893, 896, 898. No abstract available.


Neoadjuvant and adjuvant hormonal and chemotherapy for prostate cancer.

Lam ET, Glodé LM.

Hematol Oncol Clin North Am. 2013 Dec;27(6):1189-204, viii. doi: 10.1016/j.hoc.2013.08.004. Epub 2013 Sep 21. Review.


Tivozanib: practical implications for renal cell carcinoma and other solid tumors.

Berge EM, Bowles DW, Flaig TW, Lam ET, Jimeno A.

Drugs Today (Barc). 2013 May;49(5):303-15. doi: 10.1358/dot.2013.49.5.1960218. Review.


In vitro activities of PNU-100480 and linezolid against drug-susceptible and drug-resistant Mycobacterium tuberculosis isolates.

Yip PC, Kam KM, Lam ET, Chan RC, Yew WW.

Int J Antimicrob Agents. 2013 Jul;42(1):96-7. doi: 10.1016/j.ijantimicag.2013.03.002. Epub 2013 May 15. No abstract available.


Comparison of direct-measured and derived short form six dimensions (SF-6D) health preference values among chronic hepatitis B patients.

Wong CK, Lam ET, Lam CL.

Qual Life Res. 2013 Dec;22(10):2973-81. doi: 10.1007/s11136-013-0403-z. Epub 2013 Apr 6.


Rapid genome mapping in nanochannel arrays for highly complete and accurate de novo sequence assembly of the complex Aegilops tauschii genome.

Hastie AR, Dong L, Smith A, Finklestein J, Lam ET, Huo N, Cao H, Kwok PY, Deal KR, Dvorak J, Luo MC, Gu Y, Xiao M.

PLoS One. 2013;8(2):e55864. doi: 10.1371/journal.pone.0055864. Epub 2013 Feb 6.


Axitinib, a new therapeutic option in renal cell carcinoma.

Kessler ER, Bowles DW, Flaig TW, Lam ET, Jimeno A.

Drugs Today (Barc). 2012 Oct;48(10):633-44. doi: 10.1358/dot.2012.48.10.1860768. Review.


Variation in genes related to cochlear biology is strongly associated with adult-onset deafness in border collies.

Yokoyama JS, Lam ET, Ruhe AL, Erdman CA, Robertson KR, Webb AA, Williams DC, Chang ML, Hytönen MK, Lohi H, Hamilton SP, Neff MW.

PLoS Genet. 2012 Sep;8(9):e1002898. doi: 10.1371/journal.pgen.1002898. Epub 2012 Sep 13.


Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly.

Lam ET, Hastie A, Lin C, Ehrlich D, Das SK, Austin MD, Deshpande P, Cao H, Nagarajan N, Xiao M, Kwok PY.

Nat Biotechnol. 2012 Aug;30(8):771-6.


Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly.

Tranah GJ, Nalls MA, Katzman SM, Yokoyama JS, Lam ET, Zhao Y, Mooney S, Thomas F, Newman AB, Liu Y, Cummings SR, Harris TB, Yaffe K.

J Alzheimers Dis. 2012;32(2):357-72. doi: 10.3233/JAD-2012-120466.


Differences between African-American and Caucasian students on enrollment influences and barriers in kinesiology-based allied health education programs.

Barfield JP, Cobler DC, Lam ET, Zhang J, Chitiyo G.

Adv Physiol Educ. 2012 Jun;36(2):164-9. doi: 10.1152/advan.00129.2011.


Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly.

Tranah GJ, Lam ET, Katzman SM, Nalls MA, Zhao Y, Evans DS, Yokoyama JS, Pawlikowska L, Kwok PY, Mooney S, Kritchevsky S, Goodpaster BH, Newman AB, Harris TB, Manini TM, Cummings SR; Health, Aging and Body Composition Study.

Biochim Biophys Acta. 2012 Sep;1817(9):1691-700. Epub 2012 May 31.

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