Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 59

1.

Regression/eradication of gliomas in mice by a systemically-deliverable ATF5 dominant-negative peptide.

Cates CC, Arias AD, Nakayama Wong LS, Lamé MW, Sidorov M, Cayanan G, Rowland DJ, Fung J, Karpel-Massler G, Siegelin MD, Greene LA, Angelastro JM.

Oncotarget. 2016 Mar 15;7(11):12718-30. doi: 10.18632/oncotarget.7212.

2.

TGRL Lipolysis Products Induce Stress Protein ATF3 via the TGF-β Receptor Pathway in Human Aortic Endothelial Cells.

Eiselein L, Nyunt T, Lamé MW, Ng KF, Wilson DW, Rutledge JC, Aung HH.

PLoS One. 2015 Dec 28;10(12):e0145523. doi: 10.1371/journal.pone.0145523. eCollection 2015.

3.

TCDD and omeprazole prime platelets through the aryl hydrocarbon receptor (AhR) non-genomic pathway.

Pombo M, Lamé MW, Walker NJ, Huynh DH, Tablin F.

Toxicol Lett. 2015 May 19;235(1):28-36. doi: 10.1016/j.toxlet.2015.03.005. Epub 2015 Mar 19.

4.

Induction of ATF3 gene network by triglyceride-rich lipoprotein lipolysis products increases vascular apoptosis and inflammation.

Aung HH, Lame MW, Gohil K, An CI, Wilson DW, Rutledge JC.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2088-96. doi: 10.1161/ATVBAHA.113.301375. Epub 2013 Jul 18.

5.

Comparative Analysis of the Immunomodulatory Properties of Equine Adult-Derived Mesenchymal Stem Cells().

Carrade DD, Lame MW, Kent MS, Clark KC, Walker NJ, Borjesson DL.

Cell Med. 2012;4(1):1-11. Epub 2012 Jan 1.

6.

Seasonal influences on CAPs exposures: differential responses in platelet activation, serum cytokines and xenobiotic gene expression.

Tablin F, den Hartigh LJ, Aung HH, Lame MW, Kleeman MJ, Ham W, Norris JW, Pombo M, Wilson DW.

Inhal Toxicol. 2012 Jul;24(8):506-17. doi: 10.3109/08958378.2012.695815.

PMID:
22746400
7.

Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas.

Arias A, Lamé MW, Santarelli L, Hen R, Greene LA, Angelastro JM.

Oncogene. 2012 Feb 9;31(6):739-51. doi: 10.1038/onc.2011.276. Epub 2011 Jul 4.

8.

Fine particulate matter from urban ambient and wildfire sources from California's San Joaquin Valley initiate differential inflammatory, oxidative stress, and xenobiotic responses in human bronchial epithelial cells.

Nakayama Wong LS, Aung HH, Lamé MW, Wegesser TC, Wilson DW.

Toxicol In Vitro. 2011 Dec;25(8):1895-905. doi: 10.1016/j.tiv.2011.06.001. Epub 2011 Jun 15.

PMID:
21703343
9.

Comparative gene responses to collected ambient particles in vitro: endothelial responses.

Aung HH, Lame MW, Gohil K, He G, Denison MS, Rutledge JC, Wilson DW.

Physiol Genomics. 2011 Aug 16;43(15):917-29. doi: 10.1152/physiolgenomics.00051.2011. Epub 2011 Jun 7.

10.

Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive oxygen species.

den Hartigh LJ, Lamé MW, Ham W, Kleeman MJ, Tablin F, Wilson DW.

Toxicol In Vitro. 2010 Oct;24(7):1993-2002. doi: 10.1016/j.tiv.2010.08.017. Epub 2010 Aug 27.

PMID:
20801209
11.

Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole.

Nakayama Wong LS, Lamé MW, Jones AD, Wilson DW.

Chem Res Toxicol. 2010 Sep 20;23(9):1504-13. doi: 10.1021/tx1002436.

PMID:
20695460
12.

Overexpression of CD133 promotes drug resistance in C6 glioma cells.

Angelastro JM, Lamé MW.

Mol Cancer Res. 2010 Aug;8(8):1105-15. doi: 10.1158/1541-7786.MCR-09-0383. Epub 2010 Jul 27.

13.

Exposure of mice to concentrated ambient particulate matter results in platelet and systemic cytokine activation.

Wilson DW, Aung HH, Lame MW, Plummer L, Pinkerton KE, Ham W, Kleeman M, Norris JW, Tablin F.

Inhal Toxicol. 2010 Mar;22(4):267-76. doi: 10.3109/08958370903278069.

PMID:
20064101
14.

Smad signaling in the rat model of monocrotaline pulmonary hypertension.

Ramos MF, Lamé MW, Segall HJ, Wilson DW.

Toxicol Pathol. 2008 Feb;36(2):311-20. doi: 10.1177/0192623307311402. Epub 2008 Mar 26.

PMID:
18367643
15.

Differences in taurine synthesis rate among dogs relate to differences in their maintenance energy requirement.

Ko KS, Backus RC, Berg JR, Lame MW, Rogers QR.

J Nutr. 2007 May;137(5):1171-5.

PMID:
17449577
16.

Monocrotaline pyrrole induces Smad nuclear accumulation and altered signaling expression in human pulmonary arterial endothelial cells.

Ramos M, Lamé MW, Segall HJ, Wilson DW.

Vascul Pharmacol. 2007 Jun;46(6):439-48. Epub 2007 Feb 2.

17.

Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1 and F-actin, and induce apoptosis.

Eiselein L, Wilson DW, Lamé MW, Rutledge JC.

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2745-53. Epub 2007 Jan 26.

18.

The BMP type II receptor is located in lipid rafts, including caveolae, of pulmonary endothelium in vivo and in vitro.

Ramos M, Lamé MW, Segall HJ, Wilson DW.

Vascul Pharmacol. 2006 Jan;44(1):50-9. Epub 2005 Nov 3.

PMID:
16271518
19.
20.

Characterization of cytosolic glutathione S-transferases in juvenile Chinook salmon (Oncorhynchus tshawytscha).

Donham RT, Morin D, Jewell WT, Lamé MW, Segall HJ, Tjeerdema RS.

Aquat Toxicol. 2005 Jul 1;73(3):221-9. Epub 2005 Apr 26.

PMID:
15935862
21.

Characterization of glutathione S-transferases in juvenile white sturgeon.

Donham RT, Morin D, Jewell WT, Burns SA, Mitchell AE, Lamé MW, Segall HJ, Tjeerdema RS.

Aquat Toxicol. 2005 Feb 10;71(3):203-14. Epub 2005 Jan 17.

PMID:
15670627
22.

Phytochemical research using accelerator mass spectrometry.

Le Vuong T, Buchholz BA, Lamé MW, Dueker SR.

Nutr Rev. 2004 Oct;62(10):375-88. Review.

PMID:
15508907
23.

Protein targets of 1,4-benzoquinone and 1,4-naphthoquinone in human bronchial epithelial cells.

Lamé MW, Jones AD, Wilson DW, Segall HJ.

Proteomics. 2003 Apr;3(4):479-95.

PMID:
12687615
24.

Effects of monocrotaline pyrrole and thrombin on pulmonary endothelial cell junction and matrix adhesion proteins.

Taylor DW, Lamé MW, Nakayama LS, Segall HJ, Wilson DW.

Toxicology. 2003 Mar 3;184(2-3):227-40.

PMID:
12499124
25.

Long-term kinetic study of beta-carotene, using accelerator mass spectrometry in an adult volunteer.

Dueker SR, Lin Y, Buchholz BA, Schneider PD, Lamé MW, Segall HJ, Vogel JS, Clifford AJ.

J Lipid Res. 2000 Nov;41(11):1790-800.

26.

DNA damage cell checkpoint activities are altered in monocrotaline pyrrole-induced cell cycle arrest in human pulmonary artery endothelial cells.

Wilson DW, Lamé MW, Dunston SK, Segall HJ.

Toxicol Appl Pharmacol. 2000 Jul 15;166(2):69-80.

PMID:
10896848
27.

Protein targets of monocrotaline pyrrole in pulmonary artery endothelial cells.

Lamé MW, Jones AD, Wilson DW, Dunston SK, Segall HJ.

J Biol Chem. 2000 Sep 15;275(37):29091-9.

28.

Monocrotaline pyrrole interacts with actin and increases thrombin-mediated permeability in pulmonary artery endothelial cells.

Wilson DW, Lamé MW, Dunston SK, Taylor DW, Segall HJ.

Toxicol Appl Pharmacol. 1998 Sep;152(1):138-44.

PMID:
9772209
29.

Monocrotaline pyrrole induces apoptosis in pulmonary artery endothelial cells.

Thomas HC, Lamé MW, Dunston SK, Segall HJ, Wilson DW.

Toxicol Appl Pharmacol. 1998 Aug;151(2):236-44.

PMID:
9707500
30.

Prolonged cell-cycle arrest associated with altered cdc2 kinase in monocrotaline pyrrole-treated pulmonary artery endothelial cells.

Thomas HC, Lamé MW, Morin D, Wilson DW, Segall HJ.

Am J Respir Cell Mol Biol. 1998 Jul;19(1):129-42.

PMID:
9651189
31.

Involvement of cytochrome P450 3A in the metabolism and covalent binding of 14C-monocrotaline in rat liver microsomes.

Reid MJ, Lamé MW, Morin D, Wilson DW, Segall HJ.

J Biochem Mol Toxicol. 1998;12(3):157-66.

PMID:
9522275
32.

Effect of monocrotaline metabolites on glutathione levels in human and bovine pulmonary artery endothelial cells.

Reid MJ, Dunston SK, Lamé MW, Wilson DW, Morin D, Segall HJ.

Res Commun Mol Pathol Pharmacol. 1998 Jan;99(1):53-68.

PMID:
9523355
33.

Association of dehydromonocrotaline with rat red blood cells.

Lamé MW, Jones AD, Morin D, Wilson DW, Segall HJ.

Chem Res Toxicol. 1997 Jun;10(6):694-701.

PMID:
9208177
34.

Monocrotaline metabolism and distribution in Fisher 344 and Sprague-Dawley rats.

Reid MJ, Lamé MW, Morin D, Wilson DW, Segall HJ.

Comp Biochem Physiol B Biochem Mol Biol. 1997 May;117(1):115-23.

PMID:
9180020
35.

Comparative cytotoxicity of monocrotaline and its metabolites in cultured pulmonary artery endothelial cells.

Taylor DW, Wilson DW, Lamé MW, Dunston SD, Jones AD, Segall HJ.

Toxicol Appl Pharmacol. 1997 Mar;143(1):196-204.

PMID:
9073608
36.

Cell cycle alterations associated with covalent binding of monocrotaline pyrrole to pulmonary artery endothelial cell DNA.

Thomas HC, Lamé MW, Wilson DW, Segall HJ.

Toxicol Appl Pharmacol. 1996 Nov;141(1):319-29.

PMID:
8917705
37.

Purification, mass spectrometric characterization, and covalent modification of murine glutathione S-transferases.

Mitchell AE, Morin D, Lamé MW, Jones AD.

Chem Res Toxicol. 1995 Dec;8(8):1054-62.

PMID:
8605288
38.

Biliary excretion of pyrrolic metabolites of [14C]monocrotaline in the rat.

Lamé MW, Jones AD, Morin D, Segall HJ, Wilson DW.

Drug Metab Dispos. 1995 Mar;23(3):422-9.

PMID:
7628310
39.

Hydrolysis rates of pyrrolizidine alkaloids derived from Senecio jacobaea.

Dueker SR, Lamé MW, Segall HJ.

Arch Toxicol. 1995;69(10):725-8.

PMID:
8572933
40.

Metabolism of [14C]naphthalene in the B6C3F1 murine isolated perfused liver.

Tsuruda LS, Lamé MW, Jones AD.

Drug Metab Dispos. 1995 Jan;23(1):129-36.

PMID:
7720516
42.

Glutathione conjugation with the pyrrolizidine alkaloid, jacobine.

Dueker SR, Lamé MW, Jones AD, Morin D, Segall HJ.

Biochem Biophys Res Commun. 1994 Jan 28;198(2):516-22.

PMID:
8297362
43.

In vivo metabolism of retrorsine and retrorsine-N-oxide.

Chu PS, Lamé MW, Segall HJ.

Arch Toxicol. 1993;67(1):39-43.

PMID:
8452478
44.

COR pulmonale is caused by monocrotaline and dehydromonocrotaline, but not by glutathione or cysteine conjugates of dihydropyrrolizine.

Pan LC, Wilson DW, Lamé MW, Jones AD, Segall HJ.

Toxicol Appl Pharmacol. 1993 Jan;118(1):87-97.

PMID:
8430429
45.

Hydrolysis of pyrrolizidine alkaloids by guinea pig hepatic carboxylesterases.

Dueker SR, Lamé MW, Segall HJ.

Toxicol Appl Pharmacol. 1992 Nov;117(1):116-21.

PMID:
1440605
46.

Guinea pig and rat hepatic microsomal metabolism of monocrotaline.

Dueker SR, Lamé MW, Morin D, Wilson DW, Segall HJ.

Drug Metab Dispos. 1992 Mar-Apr;20(2):275-80.

PMID:
1352221
47.

Mechanisms and pathology of monocrotaline pulmonary toxicity.

Wilson DW, Segall HJ, Pan LC, Lamé MW, Estep JE, Morin D.

Crit Rev Toxicol. 1992;22(5-6):307-25. Review.

PMID:
1489509
48.

Red blood cells augment transport of reactive metabolites of monocrotaline from liver to lung in isolated and tandem liver and lung preparations.

Pan LC, Lamé MW, Morin D, Wilson DW, Segall HJ.

Toxicol Appl Pharmacol. 1991 Sep 1;110(2):336-46.

PMID:
1909819
49.

Metabolism of [14C]monocrotaline by isolated perfused rat liver.

Lamé MW, Jones AD, Morin D, Segall HJ.

Drug Metab Dispos. 1991 Mar-Apr;19(2):516-24.

PMID:
1676664
50.

[14C]monocrotaline kinetics and metabolism in the rat.

Estep JE, Lamé MW, Morin D, Jones AD, Wilson DW, Segall HJ.

Drug Metab Dispos. 1991 Jan-Feb;19(1):135-9.

PMID:
1673386

Supplemental Content

Support Center