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Items: 47


Administration of the Hyper-immune Bovine Colostrum Extract IMM-124E Ameliorates Experimental Murine Colitis.

Spalinger MR, Atrott K, Baebler K, Schwarzfischer M, Melhem H, Peres DR, Lalazar G, Rogler G, Scharl M, Frey-Wagner I.

J Crohns Colitis. 2019 May 27;13(6):785-797. doi: 10.1093/ecco-jcc/jjy213.


Glycosphingolipids Prevent APAP and HMG-CoA Reductase Inhibitors-mediated Liver Damage: A Novel Method for "Safer Drug" Formulation that Prevents Drug-induced Liver Injury.

Mizrahi M, Adar T, Lalazar G, Nachman D, El Haj M, Ben Ya'acov A, Lichtenstein Y, Shabat Y, Kanovich D, Zolotarov L, Ilan Y.

J Clin Transl Hepatol. 2018 Jun 28;6(2):127-134. doi: 10.14218/JCTH.2017.00071. Epub 2018 Feb 14.


PSMD5 Inactivation Promotes 26S Proteasome Assembly during Colorectal Tumor Progression.

Levin A, Minis A, Lalazar G, Rodriguez J, Steller H.

Cancer Res. 2018 Jul 1;78(13):3458-3468. doi: 10.1158/0008-5472.CAN-17-2296. Epub 2018 May 1.


Non coding RNA analysis in fibrolamellar hepatocellular carcinoma.

Farber BA, Lalazar G, Simon EP, Hammond WJ, Requena D, Bhanot UK, La Quaglia MP, Simon SM.

Oncotarget. 2017 Dec 15;9(12):10211-10227. doi: 10.18632/oncotarget.23325. eCollection 2018 Feb 13.


Fibrolamellar Carcinoma: Recent Advances and Unresolved Questions on the Molecular Mechanisms.

Lalazar G, Simon SM.

Semin Liver Dis. 2018 Feb;38(1):51-59. doi: 10.1055/s-0037-1621710. Epub 2018 Feb 22. Review.


Intracranial metastasis in fibrolamellar hepatocellular carcinoma.

Hammond WJ, Lalazar G, Saltsman JA, Farber BA, Danzer E, Sherpa TC, Banda CD, Andolina JR, Karimi S, Brennan CW, Torbenson MS, La Quaglia MP, Simon SM.

Pediatr Blood Cancer. 2018 Apr;65(4). doi: 10.1002/pbc.26919. Epub 2017 Dec 29.


DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.

Kastenhuber ER, Lalazar G, Houlihan SL, Tschaharganeh DF, Baslan T, Chen CC, Requena D, Tian S, Bosbach B, Wilkinson JE, Simon SM, Lowe SW.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):13076-13084. doi: 10.1073/pnas.1716483114. Epub 2017 Nov 21.


Oral Administration of β-Glucosylceramide for the Treatment of Insulin Resistance and Nonalcoholic Steatohepatitis: Results of a Double-Blind, Placebo-Controlled Trial.

Lalazar G, Zigmond E, Weksler-Zangen S, Ya'acov AB, Levy MS, Hemed N, Raz I, Ilan Y.

J Med Food. 2017 May;20(5):458-464. doi: 10.1089/jmf.2016.3753. Epub 2017 Apr 7.


Autophagy confers resistance to lipopolysaccharide-induced mouse hepatocyte injury.

Lalazar G, Ilyas G, Malik SA, Liu K, Zhao E, Amir M, Lin Y, Tanaka KE, Czaja MJ.

Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G377-86. doi: 10.1152/ajpgi.00124.2016. Epub 2016 Jul 28.


Transcriptomic characterization of fibrolamellar hepatocellular carcinoma.

Simon EP, Freije CA, Farber BA, Lalazar G, Darcy DG, Honeyman JN, Chiaroni-Clarke R, Dill BD, Molina H, Bhanot UK, La Quaglia MP, Rosenberg BR, Simon SM.

Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E5916-25. doi: 10.1073/pnas.1424894112. Epub 2015 Oct 21.


Use of the methacetin breath test to classify the risk of cirrhotic complications and mortality in patients evaluated/listed for liver transplantation.

Stravitz RT, Reuben A, Mizrahi M, Lalazar G, Brown K, Gordon SC, Ilan Y, Sanyal A.

J Hepatol. 2015 Dec;63(6):1345-51. doi: 10.1016/j.jhep.2015.07.021. Epub 2015 Jul 26.


Oral mixture of autologous colon-extracted proteins for the Crohn's disease: A double-blind trial.

Israeli E, Zigmond E, Lalazar G, Klein A, Hemed N, Goldin E, Ilan Y.

World J Gastroenterol. 2015 May 14;21(18):5685-94. doi: 10.3748/wjg.v21.i18.5685.


Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-Controlled Trial.

Lalazar G, Mizrahi M, Turgeman I, Adar T, Ben Ya'acov A, Shabat Y, Nimer A, Hemed N, Zolotarovya L, Lichtenstein Y, Lisovoder N, Samira S, Shalit I, Ellis R, Ilan Y.

J Clin Immunol. 2015 May;35(4):399-407. doi: 10.1007/s10875-015-0160-6. Epub 2015 Apr 17.


Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.

Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka KE, Czaja MJ.

Autophagy. 2015;11(2):271-84. doi: 10.1080/15548627.2015.1009787.


β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the Psammomys obesus model.

Zigmond E, Tayer-Shifman O, Lalazar G, Ben Ya'acov A, Weksler-Zangen S, Shasha D, Sklair-Levy M, Zolotarov L, Shalev Z, Kalman R, Ziv E, Raz I, Ilan Y.

J Inflamm Res. 2014 Oct 8;7:151-8. doi: 10.2147/JIR.S50508. eCollection 2014.


The effect of medical students' gender, ethnicity and attitude towards poetry-reading on the evaluation of a required, clinically-integrated poetry-based educational intervention.

Muszkat M, Barak O, Lalazar G, Mazal B, Schneider R, Levi IM, Cohen MJ, Canetti L, Ben Yehuda A, Naparstek Y.

BMC Med Educ. 2014 Sep 15;14:188. doi: 10.1186/1472-6920-14-188.


Unexpected FDG-PET uptake in the gastrointestinal tract: endoscopic and histopathological correlations.

Goldin E, Mahamid M, Koslowsky B, Shteingart S, Dubner Y, Lalazar G, Wengrower D.

World J Gastroenterol. 2014 Apr 21;20(15):4377-81. doi: 10.3748/wjg.v20.i15.4377.


Clinical problem-solving. Unfolding the diagnosis.

Lalazar G, Doviner V, Ben-Chetrit E.

N Engl J Med. 2014 Apr 3;370(14):1344-8. doi: 10.1056/NEJMcps1300859. No abstract available.


Impaired liver regeneration by β-glucosylceramide is associated with decreased fat accumulation.

Ben Ya'acov A, Lalazar G, Zolotaryova L, Steinhardt Y, Lichtentein Y, Ilan Y, Shteyer E.

J Dig Dis. 2013 Aug;14(8):425-32. doi: 10.1111/1751-2980.12062.


Alleviation of insulin resistance and liver damage by oral administration of Imm124-E is mediated by increased Tregs and associated with increased serum GLP-1 and adiponectin: results of a phase I/II clinical trial in NASH.

Mizrahi M, Shabat Y, Ben Ya'acov A, Lalazar G, Adar T, Wong V, Muller B, Rawlin G, Ilan Y.

J Inflamm Res. 2012;5:141-50. doi: 10.2147/JIR.S35227. Epub 2012 Dec 20.


Protein-Loosing Entropathy Induced by Unique Combination of CMV and HP in an Immunocompetent Patient.

Chen S, Lalazar G, Barak O, Adar T, Doviner V, Mizrahi M.

Case Rep Med. 2012;2012:361892. doi: 10.1155/2012/361892. Epub 2012 Nov 8.


Continuous 13C-methacetin breath test differentiates biliary atresia from other causes of neonatal cholestasis.

Shteyer E, Lalazar G, Hemed N, Pappo O, Granot E, Yerushalmi B, Gross E.

J Pediatr Gastroenterol Nutr. 2013 Jan;56(1):60-5. doi: 10.1097/MPG.0b013e3182638d29.


Isolated jejunal varices: a cause of occult gastrointestinal hemorrhage in a cirrhotic patient with mild portal hypertension.

Shussman N, Lalazar G, Bloom AI.

Clin Gastroenterol Hepatol. 2012 May;10(5):A32. doi: 10.1016/j.cgh.2012.01.016. Epub 2012 Jan 28. No abstract available.


Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells.

Adar T, Ben Ya'acov A, Lalazar G, Lichtenstein Y, Nahman D, Mizrahi M, Wong V, Muller B, Rawlin G, Ilan Y.

Clin Exp Immunol. 2012 Feb;167(2):252-60. doi: 10.1111/j.1365-2249.2011.04511.x.


Assessment of insulin resistance by a 13C glucose breath test: a new tool for early diagnosis and follow-up of high-risk patients.

Mizrahi M, Lalazar G, Adar T, Raz I, Ilan Y.

Nutr J. 2010 May 27;9:25. doi: 10.1186/1475-2891-9-25.


Assessment of liver function in acute or chronic liver disease by the methacetin breath test: a tool for decision making in clinical hepatology.

Lalazar G, Ilan Y.

J Breath Res. 2009 Dec;3(4):047001. doi: 10.1088/1752-7155/3/4/047001. Epub 2009 Nov 27.


Decreased STAT-1 phosphorylation by a thio analogue of beta-D-glucosylceramide is associated with altered NKT lymphocyte polarization.

Ben Ya'acov A, Lalazar G, Livovsky DM, Kanovich D, Axelrod E, Preston S, Schwarzmann G, Ilan Y.

Mol Immunol. 2009 Dec;47(2-3):526-33. doi: 10.1016/j.molimm.2009.07.030. Epub 2009 Oct 8.


Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells.

Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya'acov A, Hemed N, Kasis I, Axelrod E, Zolotarov L, Klein A, El Haj M, Gandhi R, Baecher-Allan C, Wu H, Murugaiyan G, Kivisakk P, Farez MF, Quintana FJ, Khoury SJ, Weiner HL.

J Clin Immunol. 2010 Jan;30(1):167-77. doi: 10.1007/s10875-009-9323-7. Epub 2009 Sep 16.


Beta-glycoglycosphingolipid-induced alterations of the STAT signaling pathways are dependent on CD1d and the lipid raft protein flotillin-2.

Lalazar G, Ben Ya'acov A, Livovsky DM, El Haj M, Pappo O, Preston S, Zolotarov L, Ilan Y.

Am J Pathol. 2009 Apr;174(4):1390-9. doi: 10.2353/ajpath.2009.080841. Epub 2009 Feb 26.


[Nephrogenic systemic fibrosis].

Adar T, Rubinger D, Lalazar G, Levi L, Mizrahi M, Bogot RN.

Harefuah. 2008 Oct;147(10):801-3, 837. Review. Hebrew.


Beta-glycosphingolipids improve glucose intolerance and hepatic steatosis of the Cohen diabetic rat.

Zigmond E, Zangen SW, Pappo O, Sklair-Levy M, Lalazar G, Zolotaryova L, Raz I, Ilan Y.

Am J Physiol Endocrinol Metab. 2009 Jan;296(1):E72-8. doi: 10.1152/ajpendo.90634.2008. Epub 2008 Oct 21.


[Benign recurrent intrahepatic cholestasis type-II--a rare cause of direct hyperbilirubinemia exacerbations with hepatic fibrosis].

Mizrahi M, Lalazar G, Horwich Y, Adar T, Safadi R.

Harefuah. 2008 May;147(5):381-3, 480. Hebrew.


A continuous 13C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT.

Lalazar G, Pappo O, Hershcovici T, Hadjaj T, Shubi M, Ohana H, Hemed N, Ilan Y.

J Viral Hepat. 2008 Oct;15(10):716-28. doi: 10.1111/j.1365-2893.2008.01007.x. Epub 2008 Jul 11.


Administration of beta-glycolipids overcomes an unfavorable nutritional dependent host milieu: a role for a soy-free diet and natural ligands in intrahepatic CD8+ lymphocyte trapping and NKT cell redistribution.

Livovsky DM, Lalazar G, Ben Ya'acov A, Pappo O, Preston S, Zolotaryova L, Ilan Y.

Int Immunopharmacol. 2008 Sep;8(9):1298-305. doi: 10.1016/j.intimp.2008.05.005. Epub 2008 Jun 6.


Modulation of intracellular machinery by beta-glycolipids is associated with alteration of NKT lipid rafts and amelioration of concanavalin-induced hepatitis.

Lalazar G, Ben Ya'acov A, Lador A, Livovsky DM, Pappo O, Preston S, Hareati M, Ilan Y.

Mol Immunol. 2008 Aug;45(13):3517-25. doi: 10.1016/j.molimm.2008.05.009. Epub 2008 Jun 24.


Beta-glycosphingolipids-mediated lipid raft alteration is associated with redistribution of NKT cells and increased intrahepatic CD8+ T lymphocyte trapping.

Lalazar G, Ben Ya'acov A, Eliakim-Raz N, Livovsky DM, Pappo O, Preston S, Zolotarov L, Ilan Y.

J Lipid Res. 2008 Sep;49(9):1884-93. doi: 10.1194/jlr.M800113-JLR200. Epub 2008 May 13.


Beta-glycoglycosphingolipid-induced augmentation of the anti-HBV immune response is associated with altered CD8 and NKT lymphocyte distribution: a novel adjuvant for HBV vaccination.

Mizrahi M, Lalazar G, Ben Ya'acov A, Livovsky DM, Horowitz Y, Zolotarov L, Adler R, Shouval D, Ilan Y.

Vaccine. 2008 May 19;26(21):2589-95. doi: 10.1016/j.vaccine.2008.03.026. Epub 2008 Apr 3.


Potential role of NKT regulatory cell ligands for the treatment of immune mediated colitis.

El Haj M, Ben Ya'acov A, Lalazar G, Ilan Y.

World J Gastroenterol. 2007 Nov 28;13(44):5799-804. Review.


Metastatic pancreatic neuroendocrine tumor presenting as a pituitary space occupying lesion: a case report.

Gur C, Lalazar G, Salmon A, Dubiner V, Gross DJ.

Pituitary. 2008;11(3):293-7.


Late-onset sarcoidosis after liver transplantation for primary biliary cirrhosis.

Gur C, Lalazar G, Doviner V, Fridlender ZG, Molcho V, Abu-Much S, Shalit M, Elinav E.

J Clin Gastroenterol. 2007 Mar;41(3):329-32.


Screening, prevention and treatment of viral hepatitis B reactivation in patients with haematological malignancies.

Lalazar G, Rund D, Shouval D.

Br J Haematol. 2007 Mar;136(5):699-712. Review. Erratum in: Br J Haematol. 2007 Apr;137(1):81.


Alleviation of acute and chronic graft-versus-host disease in a murine model is associated with glucocerebroside-enhanced natural killer T lymphocyte plasticity.

Ilan Y, Ohana M, Pappo O, Margalit M, Lalazar G, Engelhardt D, Rabbani E, Nagler A.

Transplantation. 2007 Feb 27;83(4):458-67.


Beta-glucosylceramide: a novel method for enhancement of natural killer T lymphoycte plasticity in murine models of immune-mediated disorders.

Zigmond E, Preston S, Pappo O, Lalazar G, Margalit M, Shalev Z, Zolotarov L, Friedman D, Alper R, Ilan Y.

Gut. 2007 Jan;56(1):82-9.


Glycolipids as immune modulatory tools.

Lalazar G, Preston S, Zigmond E, Ben Yáacov A, Ilan Y.

Mini Rev Med Chem. 2006 Nov;6(11):1249-53. Review.


Histamine dihydrochloride: actions and efficacy in the treatment of chronic hepatitis C infection.

Lalazar G, Ilan Y.

Expert Rev Anti Infect Ther. 2006 Jun;4(3):377-85. Review.


Mitral stenosis presenting with acute hearing loss.

Gur C, Lalazar G, Raphaeli G, Gilon D, Ben-Chetrit E.

PLoS Med. 2006 Jun;3(6):e233. Epub 2006 Jun 27. No abstract available.

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