Sort by
Items per page

Send to

Choose Destination

Search results

Items: 50


Redox and "Antioxidant" Properties of Fe2(μ-SH)2(CO)4(PPh3)2.

Kagalwala HN, Lalaoui N, Li QL, Liu L, Woods T, Rauchfuss TB.

Inorg Chem. 2019 Feb 18;58(4):2761-2769. doi: 10.1021/acs.inorgchem.8b03344. Epub 2019 Feb 6.


Synthetic Designs and Structural Investigations of Biomimetic Ni-Fe Thiolates.

Basu D, Bailey TS, Lalaoui N, Richers CP, Woods TJ, Rauchfuss TB, Arrigoni F, Zampella G.

Inorg Chem. 2019 Feb 18;58(4):2430-2443. doi: 10.1021/acs.inorgchem.8b02991. Epub 2019 Feb 1.


Antagonism of IAPs Enhances CAR T-cell Efficacy.

Michie J, Beavis PA, Freeman AJ, Vervoort SJ, Ramsbottom KM, Narasimhan V, Lelliott EJ, Lalaoui N, Ramsay RG, Johnstone RW, Silke J, Darcy PK, Voskoboinik I, Kearney CJ, Oliaro J.

Cancer Immunol Res. 2019 Feb;7(2):183-192. doi: 10.1158/2326-6066.CIR-18-0428. Epub 2019 Jan 16.


Recent advances in understanding inhibitor of apoptosis proteins.

Lalaoui N, Vaux DL.

F1000Res. 2018 Dec 3;7. pii: F1000 Faculty Rev-1889. doi: 10.12688/f1000research.16439.1. eCollection 2018. Review.


Tumor immune evasion arises through loss of TNF sensitivity.

Kearney CJ, Vervoort SJ, Hogg SJ, Ramsbottom KM, Freeman AJ, Lalaoui N, Pijpers L, Michie J, Brown KK, Knight DA, Sutton V, Beavis PA, Voskoboinik I, Darcy PK, Silke J, Trapani JA, Johnstone RW, Oliaro J.

Sci Immunol. 2018 May 18;3(23). pii: eaar3451. doi: 10.1126/sciimmunol.aar3451.


Electron-Rich, Diiron Bis(monothiolato) Carbonyls: C-S Bond Homolysis in a Mixed Valence Diiron Dithiolate.

Li Q, Lalaoui N, Woods TJ, Rauchfuss TB, Arrigoni F, Zampella G.

Inorg Chem. 2018 Apr 16;57(8):4409-4418. doi: 10.1021/acs.inorgchem.8b00094. Epub 2018 Apr 5.


The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues.

Vasanthakumar A, Liao Y, Teh P, Pascutti MF, Oja AE, Garnham AL, Gloury R, Tempany JC, Sidwell T, Cuadrado E, Tuijnenburg P, Kuijpers TW, Lalaoui N, Mielke LA, Bryant VL, Hodgkin PD, Silke J, Smyth GK, Nolte MA, Shi W, Kallies A.

Cell Rep. 2017 Sep 19;20(12):2906-2920. doi: 10.1016/j.celrep.2017.08.068. Epub 2017 Sep 7.


Characterization of a Borane σ Complex of a Diiron Dithiolate: Model for an Elusive Dihydrogen Adduct.

Lalaoui N, Woods T, Rauchfuss TB, Zampella G.

Organometallics. 2017 Jun 12;36(11):2054-2057. doi: 10.1021/acs.organomet.7b00236. Epub 2017 May 16.


Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer.

Merino D, Whittle JR, Vaillant F, Serrano A, Gong JN, Giner G, Maragno AL, Chanrion M, Schneider E, Pal B, Li X, Dewson G, Gräsel J, Liu K, Lalaoui N, Segal D, Herold MJ, Huang DCS, Smyth GK, Geneste O, Lessene G, Visvader JE, Lindeman GJ.

Sci Transl Med. 2017 Aug 2;9(401). pii: eaam7049. doi: 10.1126/scitranslmed.aam7049.


PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF.

Kearney CJ, Lalaoui N, Freeman AJ, Ramsbottom KM, Silke J, Oliaro J.

Cell Death Differ. 2017 Oct;24(10):1705-1716. doi: 10.1038/cdd.2017.94. Epub 2017 Jun 30.


Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.

Anderton H, Rickard JA, Varigos GA, Lalaoui N, Silke J.

J Invest Dermatol. 2017 Nov;137(11):2371-2379. doi: 10.1016/j.jid.2017.05.031. Epub 2017 Jun 22. Erratum in: J Invest Dermatol. 2018 Sep;138(9):2084.


MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.

Jaco I, Annibaldi A, Lalaoui N, Wilson R, Tenev T, Laurien L, Kim C, Jamal K, Wicky John S, Liccardi G, Chau D, Murphy JM, Brumatti G, Feltham R, Pasparakis M, Silke J, Meier P.

Mol Cell. 2017 Jun 1;66(5):698-710.e5. doi: 10.1016/j.molcel.2017.05.003. Epub 2017 May 11.


Jekyll & Hyde: The Other Life of the Death Ligand TRAIL.

Lalaoui N, Silke J.

Mol Cell. 2017 Feb 16;65(4):585-587. doi: 10.1016/j.molcel.2017.02.004.


'Did He Who Made the Lamb Make Thee?' New Developments in Treating the 'Fearful Symmetry' of Acute Myeloid Leukemia.

Brumatti G, Lalaoui N, Wei AH, Silke J.

Trends Mol Med. 2017 Mar;23(3):264-281. doi: 10.1016/j.molmed.2017.01.005. Epub 2017 Feb 11. Review.


Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways.

Tanzer MC, Khan N, Rickard JA, Etemadi N, Lalaoui N, Spall SK, Hildebrand JM, Segal D, Miasari M, Chau D, Wong WL, McKinlay M, Chunduru SK, Benetatos CA, Condon SM, Vince JE, Herold MJ, Silke J.

Cell Death Differ. 2017 Mar;24(3):481-491. doi: 10.1038/cdd.2016.147. Epub 2017 Jan 20.


Carbon-Nanotube-Supported Bio-Inspired Nickel Catalyst and Its Integration in Hybrid Hydrogen/Air Fuel Cells.

Gentil S, Lalaoui N, Dutta A, Nedellec Y, Cosnier S, Shaw WJ, Artero V, Le Goff A.

Angew Chem Int Ed Engl. 2017 Feb 6;56(7):1845-1849. doi: 10.1002/anie.201611532. Epub 2017 Jan 12.


Relevance of necroptosis in cancer.

Lalaoui N, Brumatti G.

Immunol Cell Biol. 2017 Feb;95(2):137-145. doi: 10.1038/icb.2016.120. Epub 2016 Dec 6. Review.


Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis.

Teh CE, Lalaoui N, Jain R, Policheni AN, Heinlein M, Alvarez-Diaz S, Sheridan JM, Rieser E, Deuser S, Darding M, Koay HF, Hu Y, Kupresanin F, O'Reilly LA, Godfrey DI, Smyth GK, Bouillet P, Strasser A, Walczak H, Silke J, Gray DH.

Nat Commun. 2016 Nov 18;7:13353. doi: 10.1038/ncomms13353.


Functionally distinct roles for different miR-155 expression levels through contrasting effects on gene expression, in acute myeloid leukaemia.

Narayan N, Morenos L, Phipson B, Willis SN, Brumatti G, Eggers S, Lalaoui N, Brown LM, Kosasih HJ, Bartolo RC, Zhou L, Catchpoole D, Saffery R, Oshlack A, Goodall GJ, Ekert PG.

Leukemia. 2017 Apr;31(4):808-820. doi: 10.1038/leu.2016.279. Epub 2016 Oct 14.


Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NN, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J.

Cancer Cell. 2016 Sep 12;30(3):499-500. doi: 10.1016/j.ccell.2016.08.009. Epub 2016 Sep 12. No abstract available.


The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.

Alvarez-Diaz S, Dillon CP, Lalaoui N, Tanzer MC, Rodriguez DA, Lin A, Lebois M, Hakem R, Josefsson EC, O'Reilly LA, Silke J, Alexander WS, Green DR, Strasser A.

Immunity. 2016 Sep 20;45(3):513-526. doi: 10.1016/j.immuni.2016.07.016. Epub 2016 Aug 11.


Diazonium Functionalisation of Carbon Nanotubes for Specific Orientation of Multicopper Oxidases: Controlling Electron Entry Points and Oxygen Diffusion to the Enzyme.

Lalaoui N, Holzinger M, Le Goff A, Cosnier S.

Chemistry. 2016 Jul 18;22(30):10494-500. doi: 10.1002/chem.201601377. Epub 2016 Jun 21.


The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.

Brumatti G, Ma C, Lalaoui N, Nguyen NY, Navarro M, Tanzer MC, Richmond J, Ghisi M, Salmon JM, Silke N, Pomilio G, Glaser SP, de Valle E, Gugasyan R, Gurthridge MA, Condon SM, Johnstone RW, Lock R, Salvesen G, Wei A, Vaux DL, Ekert PG, Silke J.

Sci Transl Med. 2016 May 18;8(339):339ra69. doi: 10.1126/scitranslmed.aad3099. Erratum in: Sci Transl Med. 2017 May 31;9(392):.


Ready to use bioinformatics analysis as a tool to predict immobilisation strategies for protein direct electron transfer (DET).

Cazelles R, Lalaoui N, Hartmann T, Leimkühler S, Wollenberger U, Antonietti M, Cosnier S.

Biosens Bioelectron. 2016 Nov 15;85:90-95. doi: 10.1016/j.bios.2016.04.078. Epub 2016 Apr 23.


Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.

Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NY, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J.

Cancer Cell. 2016 Feb 8;29(2):145-58. doi: 10.1016/j.ccell.2016.01.006. Erratum in: Cancer Cell. 2016 Sep 12;30(3):499-500.


Autophagy and AML--food for thought.

Lalaoui N, Johnstone R, Ekert PG.

Cell Death Differ. 2016 Jan;23(1):5-6. doi: 10.1038/cdd.2015.136. Epub 2015 Oct 30. No abstract available.


Fully Oriented Bilirubin Oxidase on Porphyrin-Functionalized Carbon Nanotube Electrodes for Electrocatalytic Oxygen Reduction.

Lalaoui N, Le Goff A, Holzinger M, Cosnier S.

Chemistry. 2015 Nov 16;21(47):16868-73. doi: 10.1002/chem.201502377. Epub 2015 Oct 9.


Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells.

Iessi E, Zischler L, Etringer A, Bergeret M, Morlé A, Jacquemin G, Morizot A, Shirley S, Lalaoui N, Elifio-Esposito SL, Fais S, Garrido C, Solary E, Micheau O.

PLoS One. 2015 May 26;10(5):e0126526. doi: 10.1371/journal.pone.0126526. eCollection 2015.


One-year stability for a glucose/oxygen biofuel cell combined with pH reactivation of the laccase/carbon nanotube biocathode.

Reuillard B, Abreu C, Lalaoui N, Le Goff A, Holzinger M, Ondel O, Buret F, Cosnier S.

Bioelectrochemistry. 2015 Dec;106(Pt A):73-6. doi: 10.1016/j.bioelechem.2015.04.009. Epub 2015 Apr 22.


A membraneless air-breathing hydrogen biofuel cell based on direct wiring of thermostable enzymes on carbon nanotube electrodes.

Lalaoui N, de Poulpiquet A, Haddad R, Le Goff A, Holzinger M, Gounel S, Mermoux M, Infossi P, Mano N, Lojou E, Cosnier S.

Chem Commun (Camb). 2015 May 1;51(35):7447-50. doi: 10.1039/c5cc02166a.


The molecular relationships between apoptosis, autophagy and necroptosis.

Lalaoui N, Lindqvist LM, Sandow JJ, Ekert PG.

Semin Cell Dev Biol. 2015 Mar;39:63-9. doi: 10.1016/j.semcdb.2015.02.003. Epub 2015 Feb 28. Review.


Wiring laccase on covalently modified graphene: carbon nanotube assemblies for the direct bio-electrocatalytic reduction of oxygen.

Lalaoui N, Le Goff A, Holzinger M, Mermoux M, Cosnier S.

Chemistry. 2015 Feb 16;21(8):3198-201. doi: 10.1002/chem.201405557. Epub 2014 Dec 11.


TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

Rickard JA, Anderton H, Etemadi N, Nachbur U, Darding M, Peltzer N, Lalaoui N, Lawlor KE, Vanyai H, Hall C, Bankovacki A, Gangoda L, Wong WW, Corbin J, Huang C, Mocarski ES, Murphy JM, Alexander WS, Voss AK, Vaux DL, Kaiser WJ, Walczak H, Silke J.

Elife. 2014 Dec 2;3. doi: 10.7554/eLife.03464.


RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T, Vince JE, Lawlor KE, Ninnis RL, Anderton H, Hall C, Spall SK, Phesse TJ, Abud HE, Cengia LH, Corbin J, Mifsud S, Di Rago L, Metcalf D, Ernst M, Dewson G, Roberts AW, Alexander WS, Murphy JM, Ekert PG, Masters SL, Vaux DL, Croker BA, Gerlic M, Silke J.

Cell. 2014 May 22;157(5):1175-88. doi: 10.1016/j.cell.2014.04.019. Epub 2014 May 8.


Rational design of a redox-labeled chiral target for an enantioselective aptamer-based electrochemical binding assay.

Moreau J, Challier L, Lalaoui N, Mavré F, Noël V, Limoges B, Schöllhorn B, Fave C.

Chemistry. 2014 Mar 3;20(10):2953-9. doi: 10.1002/chem.201302979. Epub 2014 Feb 12.


cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner.

Wong WW, Vince JE, Lalaoui N, Lawlor KE, Chau D, Bankovacki A, Anderton H, Metcalf D, O'Reilly L, Jost PJ, Murphy JM, Alexander WS, Strasser A, Vaux DL, Silke J.

Blood. 2014 Apr 17;123(16):2562-72. doi: 10.1182/blood-2013-06-510743. Epub 2014 Feb 4.


The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.

Murphy JM, Czabotar PE, Hildebrand JM, Lucet IS, Zhang JG, Alvarez-Diaz S, Lewis R, Lalaoui N, Metcalf D, Webb AI, Young SN, Varghese LN, Tannahill GM, Hatchell EC, Majewski IJ, Okamoto T, Dobson RC, Hilton DJ, Babon JJ, Nicola NA, Strasser A, Silke J, Alexander WS.

Immunity. 2013 Sep 19;39(3):443-53. doi: 10.1016/j.immuni.2013.06.018. Epub 2013 Sep 5.


Efficient direct oxygen reduction by laccases attached and oriented on pyrene-functionalized polypyrrole/carbon nanotube electrodes.

Lalaoui N, Elouarzaki K, Le Goff A, Holzinger M, Cosnier S.

Chem Commun (Camb). 2013 Oct 18;49(81):9281-3. doi: 10.1039/c3cc44994g.


Supramolecular immobilization of laccase on carbon nanotube electrodes functionalized with (methylpyrenylaminomethyl)anthraquinone for direct electron reduction of oxygen.

Bourourou M, Elouarzaki K, Lalaoui N, Agnès C, Le Goff A, Holzinger M, Maaref A, Cosnier S.

Chemistry. 2013 Jul 8;19(28):9371-5. doi: 10.1002/chem.201301043. Epub 2013 Jun 5.


Benzimidazole-based anion receptors exhibiting selectivity for lactate over pyruvate.

Hiscock JR, Gale PA, Lalaoui N, Light ME, Wells NJ.

Org Biomol Chem. 2012 Oct 14;10(38):7780-8. doi: 10.1039/c2ob26299a.


dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8.

Estornes Y, Toscano F, Virard F, Jacquemin G, Pierrot A, Vanbervliet B, Bonnin M, Lalaoui N, Mercier-Gouy P, Pachéco Y, Salaun B, Renno T, Micheau O, Lebecque S.

Cell Death Differ. 2012 Sep;19(9):1482-94. doi: 10.1038/cdd.2012.22. Epub 2012 Mar 16.


Benzimidazole-based anion receptors: tautomeric switching and selectivity.

Gale PA, Hiscock JR, Lalaoui N, Light ME, Wells NJ, Wenzel M.

Org Biomol Chem. 2012 Aug 14;10(30):5909-15. doi: 10.1039/c1ob06800h. Epub 2012 Jan 4.


Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells.

Jacquemin G, Granci V, Gallouet AS, Lalaoui N, Morlé A, Iessi E, Morizot A, Garrido C, Guillaudeux T, Micheau O.

Haematologica. 2012 Jan;97(1):38-46. doi: 10.3324/haematol.2011.046466. Epub 2011 Sep 20.


TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT.

Lalaoui N, Morlé A, Mérino D, Jacquemin G, Iessi E, Morizot A, Shirley S, Robert B, Solary E, Garrido C, Micheau O.

PLoS One. 2011;6(5):e19679. doi: 10.1371/journal.pone.0019679. Epub 2011 May 20.


Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level.

Morizot A, Mérino D, Lalaoui N, Jacquemin G, Granci V, Iessi E, Lanneau D, Bouyer F, Solary E, Chauffert B, Saas P, Garrido C, Micheau O.

Cell Death Differ. 2011 Apr;18(4):700-11. doi: 10.1038/cdd.2010.144. Epub 2010 Nov 12.


Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages.

Jacquel A, Benikhlef N, Paggetti J, Lalaoui N, Guery L, Dufour EK, Ciudad M, Racoeur C, Micheau O, Delva L, Droin N, Solary E.

Blood. 2009 Oct 22;114(17):3633-41. doi: 10.1182/blood-2009-03-208843. Epub 2009 Aug 31.


P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells.

Toscano F, Fajoui ZE, Gay F, Lalaoui N, Parmentier B, Chayvialle JA, Scoazec JY, Micheau O, Abello J, Saurin JC.

Oncogene. 2008 Jul 10;27(30):4161-71. doi: 10.1038/onc.2008.52. Epub 2008 Mar 17.


TRAIL in cancer therapy: present and future challenges.

Mérino D, Lalaoui N, Morizot A, Solary E, Micheau O.

Expert Opin Ther Targets. 2007 Oct;11(10):1299-314. Review.


Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.

Mérino D, Lalaoui N, Morizot A, Schneider P, Solary E, Micheau O.

Mol Cell Biol. 2006 Oct;26(19):7046-55.


Dynamics of HPV16 DNA load reflect the natural history of cervical HPV-associated lesions.

Monnier-Benoit S, Dalstein V, Riethmuller D, Lalaoui N, Mougin C, Prétet JL.

J Clin Virol. 2006 Mar;35(3):270-7. Epub 2005 Oct 7. Erratum in: J Clin Virol. 2006 Oct;37(2):137.


Supplemental Content

Loading ...
Support Center