Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 30

1.

Integrative Analysis Reveals Subtype-Specific Regulatory Determinants in Triple Negative Breast Cancer.

Huang S, Xu W, Hu P, Lakowski TM.

Cancers (Basel). 2019 Apr 10;11(4). pii: E507. doi: 10.3390/cancers11040507.

2.

Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections.

Zelenitsky SA, Calic D, Arora RC, Grocott HP, Lakowski TM, Lillico R, Ariano RE.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01360-18. doi: 10.1128/AAC.01360-18. Print 2018 Nov.

3.

Selective DOT1L, LSD1, and HDAC Class I Inhibitors Reduce HOXA9 Expression in MLL-AF9 Rearranged Leukemia Cells, But Dysregulate the Expression of Many Histone-Modifying Enzymes.

Lillico R, Lawrence CK, Lakowski TM.

J Proteome Res. 2018 Aug 3;17(8):2657-2667. doi: 10.1021/acs.jproteome.8b00118. Epub 2018 Jul 17.

PMID:
29972300
4.

Absolute Oral Bioavailability of Creatine Monohydrate in Rats: Debunking a Myth.

Alraddadi EA, Lillico R, Vennerstrom JL, Lakowski TM, Miller DW.

Pharmaceutics. 2018 Mar 8;10(1). pii: E31. doi: 10.3390/pharmaceutics10010031.

5.

Evaluation of cefazolin antimicrobial prophylaxis during cardiac surgery with cardiopulmonary bypass.

Calic D, Ariano RE, Arora RC, Grocott HP, Lakowski TM, Lillico R, Zelenitsky SA.

J Antimicrob Chemother. 2018 Mar 1;73(3):768-771. doi: 10.1093/jac/dkx439.

PMID:
29237016
6.

Increased Post-Translational Lysine Acetylation of Myelin Basic Protein Is Associated with Peak Neurological Disability in a Mouse Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis.

Lillico R, Zhou T, Khorshid Ahmad T, Stesco N, Gozda K, Truong J, Kong J, Lakowski TM, Namaka M.

J Proteome Res. 2018 Jan 5;17(1):55-62. doi: 10.1021/acs.jproteome.7b00270. Epub 2017 Nov 20.

PMID:
29111742
7.

Disposition, Metabolism and Histone Deacetylase and Acetyltransferase Inhibition Activity of Tetrahydrocurcumin and Other Curcuminoids.

Novaes JT, Lillico R, Sayre CL, Nagabushnam K, Majeed M, Chen Y, Ho EA, Oliveira ALP, Martinez SE, Alrushaid S, Davies NM, Lakowski TM.

Pharmaceutics. 2017 Oct 12;9(4). pii: E45. doi: 10.3390/pharmaceutics9040045.

8.

Pharmacokinetic Analysis of an Oral Multicomponent Joint Dietary Supplement (Phycox®) in Dogs.

Martinez SE, Lillico R, Lakowski TM, Martinez SA, Davies NM.

Pharmaceutics. 2017 Aug 18;9(3). pii: E30. doi: 10.3390/pharmaceutics9030030.

9.
10.

Simultaneous quantification of reparixin and paclitaxel in plasma and urine using ultra performance liquid chromatography-tandem mass spectroscopy (UHPLC-MS/MS): Application to a preclinical pharmacokinetic study in rats.

Malhi S, Stesco N, Alrushaid S, Lakowski TM, Davies NM, Gu X.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 1;1046:165-171. doi: 10.1016/j.jchromb.2016.12.015. Epub 2017 Feb 3.

PMID:
28187377
11.

PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X.

Vhuiyan MI, Pak ML, Park MA, Thomas D, Lakowski TM, Chalfant CE, Frankel A.

J Biochem. 2017 Jul 1;162(1):17-25. doi: 10.1093/jb/mvw102.

12.

Quantification of cefazolin in serum and adipose tissue by ultra high performance liquid chromatography-Tandem mass spectrometry (UHPLC-MS/MS): application to a pilot study of obese women undergoing cesarean delivery.

Lillico R, Sayre CL, Sitar DS, Davies NM, Baron CM, Lakowski TM.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 15;1031:94-98. doi: 10.1016/j.jchromb.2016.07.032. Epub 2016 Jul 18.

PMID:
27469905
13.

Inhibitors of enzymes catalyzing modifications to histone lysine residues: structure, function and activity.

Lillico R, Stesco N, Khorshid Amhad T, Cortes C, Namaka MP, Lakowski TM.

Future Med Chem. 2016 May;8(8):879-97. doi: 10.4155/fmc-2016-0021. Epub 2016 May 13. Review.

PMID:
27173004
14.

HDAC inhibitors induce global changes in histone lysine and arginine methylation and alter expression of lysine demethylases.

Lillico R, Sobral MG, Stesco N, Lakowski TM.

J Proteomics. 2016 Feb 5;133:125-133. doi: 10.1016/j.jprot.2015.12.018. Epub 2015 Dec 22.

PMID:
26721445
15.

Physiologic Changes in the Heart Following Cessation of Mechanical Ventilation in a Porcine Model of Donation After Circulatory Death: Implications for Cardiac Transplantation.

White CW, Lillico R, Sandha J, Hasanally D, Wang F, Ambrose E, Müller A, Rachid O, Li Y, Xiang B, Le H, Messer S, Ali A, Large SR, Lee TW, Dixon IM, Lakowski TM, Simons K, Arora RC, Tian G, Nagendran J, Hryshko LV, Freed DH.

Am J Transplant. 2016 Mar;16(3):783-93. doi: 10.1111/ajt.13543. Epub 2015 Dec 11.

16.

Arginine methylation in yeast proteins during stationary-phase growth and heat shock.

Lakowski TM, Pak ML, Szeitz A, Thomas D, Vhuiyan MI, Clement B, Frankel A.

Amino Acids. 2015 Dec;47(12):2561-71. doi: 10.1007/s00726-015-2047-5. Epub 2015 Jul 19.

PMID:
26189025
17.

Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS).

KhorshidAhmad T, Acosta C, Cortes C, Lakowski TM, Gangadaran S, Namaka M.

Mol Neurobiol. 2016 Mar;53(2):1092-107. doi: 10.1007/s12035-014-9074-1. Epub 2015 Jan 13. Review.

PMID:
25579386
18.

Protein arginine N-methyltransferase substrate preferences for different nη-substituted arginyl peptides.

Thomas D, Koopmans T, Lakowski TM, Kreinin H, Vhuiyan MI, Sedlock SA, Bui JM, Martin NI, Frankel A.

Chembiochem. 2014 Jul 21;15(11):1607-13. doi: 10.1002/cbic.201402045. Epub 2014 Jul 8.

PMID:
25044481
19.
20.

MS³ fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM³.

Lakowski TM, Szeitz A, Pak ML, Thomas D, Vhuiyan MI, Kotthaus J, Clement B, Frankel A.

J Proteomics. 2013 Mar 27;80:43-54. doi: 10.1016/j.jprot.2013.01.003. Epub 2013 Jan 17.

PMID:
23333926
21.

A protein arginine N-methyltransferase 1 (PRMT1) and 2 heteromeric interaction increases PRMT1 enzymatic activity.

Pak ML, Lakowski TM, Thomas D, Vhuiyan MI, Hüsecken K, Frankel A.

Biochemistry. 2011 Sep 27;50(38):8226-40. doi: 10.1021/bi200644c. Epub 2011 Aug 29.

PMID:
21851090
22.

Peptidic partial bisubstrates as inhibitors of the protein arginine N-methyltransferases.

't Hart P, Lakowski TM, Thomas D, Frankel A, Martin NI.

Chembiochem. 2011 Jun 14;12(9):1427-32. doi: 10.1002/cbic.201100074. Epub 2011 May 10. No abstract available.

PMID:
21560220
23.

Förster resonance energy transfer measurements of cofactor-dependent effects on protein arginine N-methyltransferase homodimerization.

Thomas D, Lakowski TM, Pak ML, Kim JJ, Frankel A.

Protein Sci. 2010 Nov;19(11):2141-51. doi: 10.1002/pro.492.

24.

Nη-substituted arginyl peptide inhibitors of protein arginine N-methyltransferases.

Lakowski TM, 't Hart P, Ahern CA, Martin NI, Frankel A.

ACS Chem Biol. 2010 Nov 19;5(11):1053-63. doi: 10.1021/cb100161u.

PMID:
20701328
25.

Approaches to measuring the activities of protein arginine N-methyltransferases.

Lakowski TM, Zurita-Lopez C, Clarke SG, Frankel A.

Anal Biochem. 2010 Feb 1;397(1):1-11. doi: 10.1016/j.ab.2009.09.021. Epub 2009 Sep 15. Review. No abstract available.

26.

Sources of S-adenosyl-L-homocysteine background in measuring protein arginine N-methyltransferase activity using tandem mass spectrometry.

Lakowski TM, Frankel A.

Anal Biochem. 2010 Jan 1;396(1):158-60. doi: 10.1016/j.ab.2009.08.043. Epub 2009 Sep 3.

PMID:
19733141
27.
28.

A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism.

Lakowski TM, Frankel A.

J Biol Chem. 2008 Apr 11;283(15):10015-25. doi: 10.1074/jbc.M710176200. Epub 2008 Feb 8.

29.

Peptide binding by a fragment of calmodulin composed of EF-hands 2 and 3.

Lakowski TM, Lee GM, Lelj-Garolla B, Okon M, Reid RE, McIntosh LP.

Biochemistry. 2007 Jul 24;46(29):8525-36. Epub 2007 Jun 27.

PMID:
17595060
30.

Calcium-induced folding of a fragment of calmodulin composed of EF-hands 2 and 3.

Lakowski TM, Lee GM, Okon M, Reid RE, McIntosh LP.

Protein Sci. 2007 Jun;16(6):1119-32. Epub 2007 May 1.

Supplemental Content

Loading ...
Support Center