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Items: 37

1.

Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality: data from the FINNAKI observational study.

Inkinen N, Pettilä V, Lakkisto P, Kuitunen A, Jukarainen S, Bendel S, Inkinen O, Ala-Kokko T, Vaara ST; FINNAKI Study Group.

Ann Intensive Care. 2019 Sep 11;9(1):103. doi: 10.1186/s13613-019-0575-y.

2.

The association of endothelial injury and systemic inflammation with perioperative myocardial infarction.

Ollila A, Vikatmaa L, Virolainen J, Nisula S, Lakkisto P, Vikatmaa P, Tikkanen I, Venermo M, Pettilä V.

Ann Clin Biochem. 2019 Nov;56(6):674-683. doi: 10.1177/0004563219873357. Epub 2019 Sep 4. No abstract available.

PMID:
31409092
3.

Heme oxygenase-1 repeat polymorphism in septic acute kidney injury.

Vilander LM, Vaara ST, Donner KM, Lakkisto P, Kaunisto MA, Pettilä V; FINNAKI Study Group.

PLoS One. 2019 May 23;14(5):e0217291. doi: 10.1371/journal.pone.0217291. eCollection 2019.

4.

Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish.

Narumanchi S, Kalervo K, Perttunen S, Wang H, Immonen K, Kosonen R, Laine M, Ruskoaho H, Tikkanen I, Lakkisto P, Paavola J.

J Cardiovasc Dev Dis. 2019 Apr 4;6(2). pii: E16. doi: 10.3390/jcdd6020016.

5.

Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129.

Gomes CPC, Ágg B, Andova A, Arslan S, Baker A, Barteková M, Beis D, Betsou F, Wettinger SB, Bugarski B, Condorelli G, Silva GJJD, Danilin S, de Gonzalo-Calvo D, Buil A, Carmo-Fonseca M, Enguita FJ, Felekkis K, Ferdinandy P, Gyöngyösi M, Hackl M, Karaduzovic-Hadziabdic K, Hellemans J, Heymans S, Hlavackova M, Hoydal MA, Jankovic A, Jusic A, Kardassis D, Kerkelä R, Kuster GM, Lakkisto P, Leszek P, Lustrek M, Maegdefessel L, Martelli F, Novella S, O'Brien T, Papaneophytou C, Pedrazzini T, Pinet F, Popescu O, Potočnjak I, Robinson E, Sasson S, Scholz M, Simionescu M, Stoll M, Varga ZV, Vinciguerra M, Xuereb A, Yilmaz MB, Emanueli C, Devaux Y, on behalf of the EU-CardioRNA COST Action (CA17129).

Noncoding RNA. 2019 Mar 29;5(2). pii: E31. doi: 10.3390/ncrna5020031.

6.

Circulating levels of microRNA 423-5p are associated with 90 day mortality in cardiogenic shock.

Jäntti T, Segersvärd H, Tolppanen H, Tarvasmäki T, Lassus J, Devaux Y, Vausort M, Pulkki K, Sionis A, Bayes-Genis A, Tikkanen I, Lakkisto P, Harjola VP.

ESC Heart Fail. 2019 Feb;6(1):98-102. doi: 10.1002/ehf2.12377. Epub 2018 Nov 24.

7.

Circulating MiRNA Dynamics in ST-Segment Elevation Myocardial Infarction-driven Cardiogenic Shock.

Iborra-Egea O, Rueda F, Lakkisto P, Harjola VP, García-García C, Bayes-Genis A.

Rev Esp Cardiol (Engl Ed). 2019 Sep;72(9):783-786. doi: 10.1016/j.rec.2018.10.008. Epub 2018 Nov 22. English, Spanish. No abstract available.

PMID:
30471962
8.

Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach.

Lalowski MM, Björk S, Finckenberg P, Soliymani R, Tarkia M, Calza G, Blokhina D, Tulokas S, Kankainen M, Lakkisto P, Baumann M, Kankuri E, Mervaala E.

Front Physiol. 2018 Apr 11;9:365. doi: 10.3389/fphys.2018.00365. eCollection 2018.

9.

Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia.

Kaartokallio T, Utge S, Klemetti MM, Paananen J, Pulkki K, Romppanen J, Tikkanen I, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Lakkisto P, Laivuori H.

Hypertension. 2018 Jan;71(1):95-102. doi: 10.1161/HYPERTENSIONAHA.117.10425. Epub 2017 Dec 4.

PMID:
29203625
10.

Endothelin A receptor blocker and calcimimetic in the adenine rat model of chronic renal insufficiency.

Törmänen S, Pörsti I, Lakkisto P, Tikkanen I, Niemelä O, Paavonen T, Mustonen J, Eräranta A.

BMC Nephrol. 2017 Oct 27;18(1):323. doi: 10.1186/s12882-017-0742-z.

11.

Carbon monoxide releasing molecule improves structural and functional cardiac recovery after myocardial injury.

Segersvärd H, Lakkisto P, Hänninen M, Forsten H, Siren J, Immonen K, Kosonen R, Sarparanta M, Laine M, Tikkanen I.

Eur J Pharmacol. 2018 Jan 5;818:57-66. doi: 10.1016/j.ejphar.2017.10.031. Epub 2017 Oct 18.

PMID:
29055786
12.

Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish.

Dash SN, Narumanchi S, Paavola J, Perttunen S, Wang H, Lakkisto P, Tikkanen I, Lehtonen S.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016. Epub 2017 Mar 24.

13.

Urinary Biomarkers Indicative of Apoptosis and Acute Kidney Injury in the Critically Ill.

Vaara ST, Lakkisto P, Immonen K, Tikkanen I, Ala-Kokko T, Pettilä V; FINNAKI Study Group.

PLoS One. 2016 Feb 26;11(2):e0149956. doi: 10.1371/journal.pone.0149956. eCollection 2016.

14.

PLASMA HEME OXYGENASE-1 IN PATIENTS RESUSCITATED FROM OUT-OF-HOSPITAL CARDIAC ARREST.

Siren J, Vaahersalo J, Skrifvars M, Pettilä V, Tiainen M, Tikkanen I, Lakkisto P; FINNRESUSCI Study Group.

Shock. 2016 Mar;45(3):320-5. doi: 10.1097/SHK.0000000000000521.

PMID:
26555743
15.

Human plasma cell-free DNA as a predictor of infectious complications of neutropenic fever in hematological patients.

Purhonen AK, Juutilainen A, Vänskä M, Lehtikangas M, Lakkisto P, Hämäläinen S, Koivula I, Jantunen E, Pulkki K.

Infect Dis (Lond). 2015 Apr;47(4):255-9. doi: 10.3109/00365548.2014.985711. Epub 2015 Feb 9.

PMID:
25664374
16.

Phosphate binding reduces aortic angiotensin-converting enzyme and enhances nitric oxide bioactivity in experimental renal insufficiency.

Eräranta A, Törmänen S, Kööbi P, Vehmas TI, Lakkisto P, Tikkanen I, Moilanen E, Niemelä O, Mustonen J, Pörsti I.

Am J Nephrol. 2014;39(5):400-8. doi: 10.1159/000362507. Epub 2014 May 6.

PMID:
24818649
17.

Microsatellite polymorphism in the heme oxygenase-1 promoter is associated with nonsevere and late-onset preeclampsia.

Kaartokallio T, Klemetti MM, Timonen A, Uotila J, Heinonen S, Kajantie E, Kere J, Kivinen K, Pouta A, Lakkisto P, Laivuori H.

Hypertension. 2014 Jul;64(1):172-7. doi: 10.1161/HYPERTENSIONAHA.114.03337. Epub 2014 May 5.

PMID:
24799610
18.

Effects of angiotensin II blockade on cardiomyocyte regeneration after myocardial infarction in rats.

Segersvärd H, Lakkisto P, Forsten H, Immonen K, Kosonen R, Palojoki E, Kankuri E, Harjula A, Laine M, Tikkanen I.

J Renin Angiotensin Aldosterone Syst. 2015 Mar;16(1):92-102. doi: 10.1177/1470320313487567. Epub 2013 Apr 29.

PMID:
23629679
19.

Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats.

Eräranta A, Riutta A, Fan M, Koskela J, Tikkanen I, Lakkisto P, Niemelä O, Parkkinen J, Mustonen J, Pörsti I.

Am J Nephrol. 2012;35(5):401-8. doi: 10.1159/000337942. Epub 2012 Apr 19.

PMID:
22517117
20.

Heat shock attenuates VEGF expression in three-dimensional myoblast sheets deteriorating therapeutic efficacy in heart failure.

Augustin M, Ali Asim Mahar M, Lakkisto P, Tikkanen I, Vento A, Patila T, Harjula A.

Med Sci Monit. 2011 Dec;17(12):BR345-53.

21.

Heme oxygenase-1 induction protects the heart and modulates cellular and extracellular remodelling after myocardial infarction in rats.

Lakkisto P, Siren JM, Kytö V, Forsten H, Laine M, Pulkki K, Tikkanen I.

Exp Biol Med (Maywood). 2011 Dec;236(12):1437-48. doi: 10.1258/ebm.2011.011148. Epub 2011 Nov 15.

PMID:
22087023
22.

Plasma cell-free DNA in patients needing mechanical ventilation.

Okkonen M, Lakkisto P, Korhonen AM, Parviai-nen I, Reinikainen M, Varpula T, Pettilä V; FINNALI Study Group.

Crit Care. 2011 Aug 12;15(4):R196. doi: 10.1186/cc10357.

23.

Effects of levosimendan on cardiac gene expression profile and post-infarct cardiac remodelling in diabetic Goto-Kakizaki rats.

Vahtola E, Storvik M, Louhelainen M, Merasto S, Lakkisto P, Lakkisto J, Tikkanen I, Kaheinen P, Levijoki J, Mervaala E.

Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):387-97. doi: 10.1111/j.1742-7843.2011.00743.x. Epub 2011 Aug 17.

24.

hHGF overexpression in myoblast sheets enhances their angiogenic potential in rat chronic heart failure.

Siltanen A, Kitabayashi K, Lakkisto P, Mäkelä J, Pätilä T, Ono M, Tikkanen I, Sawa Y, Kankuri E, Harjula A.

PLoS One. 2011 Apr 26;6(4):e19161. doi: 10.1371/journal.pone.0019161.

25.

Heme oxygenase 1 polymorphisms and plasma concentrations in critically ill patients.

Saukkonen K, Lakkisto P, Kaunisto MA, Varpula M, Voipio-Pulkki LM, Varpula T, Pettilä V, Pulkki K.

Shock. 2010 Dec;34(6):558-64. doi: 10.1097/SHK.0b013e3181e14de9.

PMID:
20386498
26.

Heme oxygenase-1 and carbon monoxide promote neovascularization after myocardial infarction by modulating the expression of HIF-1alpha, SDF-1alpha and VEGF-B.

Lakkisto P, Kytö V, Forsten H, Siren JM, Segersvärd H, Voipio-Pulkki LM, Laine M, Pulkki K, Tikkanen I.

Eur J Pharmacol. 2010 Jun 10;635(1-3):156-64. doi: 10.1016/j.ejphar.2010.02.050. Epub 2010 Mar 19.

PMID:
20303947
27.

Angiotensin receptors in the eyes of arterial hypertensive rats.

Vaajanen A, Lakkisto P, Virtanen I, Kankuri E, Oksala O, Vapaatalo H, Tikkanen I.

Acta Ophthalmol. 2010 Jun;88(4):431-8. doi: 10.1111/j.1755-3768.2009.01563.x. Epub 2009 Sep 16.

28.

Paricalcitol and renin-angiotensin components in remnant kidneys.

Eräranta A, Lakkisto PJ, Tikkanen I, Mustonen JT, Pörsti IH.

Kidney Int. 2009 Feb;75(3):339-40; author reply 340. doi: 10.1038/ki.2008.593. No abstract available.

29.

The heme oxygenase inducer hemin protects against cardiac dysfunction and ventricular fibrillation in ischaemic/reperfused rat hearts: role of connexin 43.

Lakkisto P, Csonka C, Fodor G, Bencsik P, Voipio-Pulkki LM, Ferdinandy P, Pulkki K.

Scand J Clin Lab Invest. 2009;69(2):209-18. doi: 10.1080/00365510802474392.

PMID:
18946777
30.

Oxonic acid-induced hyperuricemia elevates plasma aldosterone in experimental renal insufficiency.

Eräranta A, Kurra V, Tahvanainen AM, Vehmas TI, Kööbi P, Lakkisto P, Tikkanen I, Niemelä OJ, Mustonen JT, Pörsti IH.

J Hypertens. 2008 Aug;26(8):1661-8. doi: 10.1097/HJH.0b013e328303205d.

PMID:
18622246
31.

Cell-free plasma DNA as a predictor of outcome in severe sepsis and septic shock.

Saukkonen K, Lakkisto P, Pettilä V, Varpula M, Karlsson S, Ruokonen E, Pulkki K; Finnsepsis Study Group.

Clin Chem. 2008 Jun;54(6):1000-7. doi: 10.1373/clinchem.2007.101030. Epub 2008 Apr 17.

32.

Activation of protective and damaging components of the cardiac renin-angiotensin system after myocardial infarction in experimental diabetes.

Bäcklund T, Lakkisto P, Palojoki E, Grönholm T, Saraste A, Finckenberg P, Mervaala E, Tikkanen I, Laine M.

J Renin Angiotensin Aldosterone Syst. 2007 Jun;8(2):66-73.

PMID:
17703432
33.

Association of cell-free plasma DNA with hospital mortality and organ dysfunction in intensive care unit patients.

Saukkonen K, Lakkisto P, Varpula M, Varpula T, Voipio-Pulkki LM, Pettilä V, Pulkki K.

Intensive Care Med. 2007 Sep;33(9):1624-7. Epub 2007 May 31.

PMID:
17541553
34.

Glutathione depletion and cardiomyocyte apoptosis in viral myocarditis.

Kytö V, Lapatto R, Lakkisto P, Saraste A, Voipio-Pulkki LM, Vuorinen T, Pulkki K.

Eur J Clin Invest. 2004 Mar;34(3):167-75.

PMID:
15025674
35.

Sustained cardiomyocyte apoptosis and left ventricular remodelling after myocardial infarction in experimental diabetes.

Bäcklund T, Palojoki E, Saraste A, Eriksson A, Finckenberg P, Kytö V, Lakkisto P, Mervaala E, Voipio-Pulkki LM, Laine M, Tikkanen I.

Diabetologia. 2004 Feb;47(2):325-30. Epub 2004 Jan 13.

PMID:
14722653
36.

Effect of vasopeptidase inhibitor omapatrilat on cardiomyocyte apoptosis and ventricular remodeling in rat myocardial infarction.

Bäcklund T, Palojoki E, Saraste A, Grönholm T, Eriksson A, Lakkisto P, Vuolteenaho O, Nieminen MS, Voipio-Pulkki LM, Laine M, Tikkanen I.

Cardiovasc Res. 2003 Mar;57(3):727-37.

PMID:
12618234
37.

Expression of heme oxygenase-1 in response to myocardial infarction in rats.

Lakkisto P, Palojoki E, Bäcklund T, Saraste A, Tikkanen I, Voipio-Pulkki LM, Pulkki K.

J Mol Cell Cardiol. 2002 Oct;34(10):1357-65.

PMID:
12392996

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