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Items: 33

1.

Dictyostelium as a Model to Assess Site-Specific ADP-Ribosylation Events.

Kolb AL, Hsu DW, Wallis ABA, Ura S, Rakhimova A, Pears CJ, Lakin ND.

Methods Mol Biol. 2018;1813:125-148. doi: 10.1007/978-1-4939-8588-3_9.

PMID:
30097865
2.

PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation.

Ronson GE, Piberger AL, Higgs MR, Olsen AL, Stewart GS, McHugh PJ, Petermann E, Lakin ND.

Nat Commun. 2018 Feb 21;9(1):746. doi: 10.1038/s41467-018-03159-2.

3.
4.

Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks.

Rakhimova A, Ura S, Hsu DW, Wang HY, Pears CJ, Lakin ND.

Sci Rep. 2017 Mar 2;7:43750. doi: 10.1038/srep43750.

5.

The role of ADP-ribosylation in regulating DNA interstrand crosslink repair.

Gunn AR, Banos-Pinero B, Paschke P, Sanchez-Pulido L, Ariza A, Day J, Emrich M, Leys D, Ponting CP, Ahel I, Lakin ND.

J Cell Sci. 2016 Oct 15;129(20):3845-3858. Epub 2016 Sep 1.

6.

Emerging models for DNA repair: Dictyostelium discoideum as a model for nonhomologous end-joining.

Pears CJ, Lakin ND.

DNA Repair (Amst). 2014 May;17:121-31. doi: 10.1016/j.dnarep.2014.01.008. Epub 2014 Feb 16.

PMID:
24548787
7.

Nonhomologous end-joining promotes resistance to DNA damage in the absence of an ADP-ribosyltransferase that signals DNA single strand breaks.

Couto CA, Hsu DW, Teo R, Rakhimova A, Lempidaki S, Pears CJ, Lakin ND.

J Cell Sci. 2013 Aug 1;126(Pt 15):3452-61. doi: 10.1242/jcs.128769. Epub 2013 Jun 7.

8.

Investigation of DNA repair pathway activity.

Couto AM, Lakin ND, Pears CJ.

Methods Mol Biol. 2013;983:295-310. doi: 10.1007/978-1-62703-302-2_16.

PMID:
23494314
9.

The role of ADP-ribosylation in regulating DNA double-strand break repair.

Pears CJ, Couto CA, Wang HY, Borer C, Kiely R, Lakin ND.

Cell Cycle. 2012 Jan 1;11(1):48-56. doi: 10.4161/cc.11.1.18793. Epub 2012 Jan 1. Review.

10.

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks.

Couto CA, Wang HY, Green JC, Kiely R, Siddaway R, Borer C, Pears CJ, Lakin ND.

J Cell Biol. 2011 Aug 8;194(3):367-75. doi: 10.1083/jcb.201012132. Epub 2011 Aug 1.

11.

DNA double-strand break repair pathway choice in Dictyostelium.

Hsu DW, Kiely R, Couto CA, Wang HY, Hudson JJ, Borer C, Pears CJ, Lakin ND.

J Cell Sci. 2011 May 15;124(Pt 10):1655-63. doi: 10.1242/jcs.081471.

12.

Recruitment of 9-1-1 to sites of DNA damage through cell cycle-dependent processing of DNA lesions.

Lakin ND.

Cell Cycle. 2009 Jul 1;8(13):1981. Epub 2009 Jul 1. No abstract available.

PMID:
19550150
13.

ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage.

Medhurst AL, Warmerdam DO, Akerman I, Verwayen EH, Kanaar R, Smits VA, Lakin ND.

J Cell Sci. 2008 Dec 1;121(Pt 23):3933-40. doi: 10.1242/jcs.033688.

14.

DNA damage signaling and repair in Dictyostelium discoideum.

Hsu DW, Gaudet P, Hudson JJ, Pears CJ, Lakin ND.

Cell Cycle. 2006 Apr;5(7):702-8. Epub 2006 Apr 1. Review.

PMID:
16582628
15.

Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex.

Adams KE, Medhurst AL, Dart DA, Lakin ND.

Oncogene. 2006 Jun 29;25(28):3894-904. Epub 2006 Feb 13.

16.

DNA-PKcs-dependent signaling of DNA damage in Dictyostelium discoideum.

Hudson JJ, Hsu DW, Guo K, Zhukovskaya N, Liu PH, Williams JG, Pears CJ, Lakin ND.

Curr Biol. 2005 Oct 25;15(20):1880-5.

17.

Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase.

Dart DA, Adams KE, Akerman I, Lakin ND.

J Biol Chem. 2004 Apr 16;279(16):16433-40. Epub 2004 Feb 9.

18.

Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest.

Davies SL, North PS, Dart A, Lakin ND, Hickson ID.

Mol Cell Biol. 2004 Feb;24(3):1279-91.

19.

Regulation of p53 in response to DNA damage.

Lakin ND, Jackson SP.

Oncogene. 1999 Dec 13;18(53):7644-55. Review.

20.

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

Smith GC, Cary RB, Lakin ND, Hann BC, Teo SH, Chen DJ, Jackson SP.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11134-9.

21.

Cleavage and inactivation of ATM during apoptosis.

Smith GC, d'Adda di Fagagna F, Lakin ND, Jackson SP.

Mol Cell Biol. 1999 Sep;19(9):6076-84.

22.

The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.

Lakin ND, Hann BC, Jackson SP.

Oncogene. 1999 Jul 8;18(27):3989-95.

23.

DNA-dependent protein kinase and related proteins.

Smith GC, Divecha N, Lakin ND, Jackson SP.

Biochem Soc Symp. 1999;64:91-104. Review.

PMID:
10207623
24.

The p53-mediated DNA damage response to ionizing radiation in fibroblasts from ataxia-without-telangiectasia patients.

Jongmans W, Vuillaume M, Kleijer WJ, Lakin ND, Hall J.

Int J Radiat Biol. 1998 Sep;74(3):287-95.

PMID:
9737532
25.

Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors.

Morris PJ, Lakin ND, Dawson SJ, Ryabinin AE, Kilimann MW, Wilson MC, Latchman DS.

Brain Res Mol Brain Res. 1996 Dec 31;43(1-2):279-85.

PMID:
9037543
26.

Analysis of the ATM protein in wild-type and ataxia telangiectasia cells.

Lakin ND, Weber P, Stankovic T, Rottinghaus ST, Taylor AM, Jackson SP.

Oncogene. 1996 Dec 19;13(12):2707-16.

PMID:
9000145
27.

The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site.

Budhram-Mahadeo V, Morris PJ, Lakin ND, Dawson SJ, Latchman DS.

J Biol Chem. 1996 Apr 12;271(15):9108-13.

28.

Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor.

Lakin ND, Morris PJ, Theil T, Sato TN, Möröy T, Wilson MC, Latchman DS.

J Biol Chem. 1995 Jun 30;270(26):15858-63.

29.

Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein.

Budhram-Mahadeo V, Morris PJ, Lakin ND, Theil T, Ching GY, Lillycrop KA, Möröy T, Liem RK, Latchman DS.

J Biol Chem. 1995 Feb 10;270(6):2853-8.

30.

Down regulation of the octamer binding protein Oct-1 during growth arrest and differentiation of a neuronal cell line.

Lakin ND, Palmer R, Lillycrop KA, Howard MK, Burke LC, Thomas NS, Latchman DS.

Brain Res Mol Brain Res. 1995 Jan;28(1):47-54.

PMID:
7707877
31.
32.
33.

A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells.

Lillycrop KA, Budrahan VS, Lakin ND, Terrenghi G, Wood JN, Polak JM, Latchman DS.

Nucleic Acids Res. 1992 Oct 11;20(19):5093-6.

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