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Items: 1 to 50 of 99

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Altered levels of hsromega lncRNAs further enhance Ras signaling during ectopically activated Ras induced R7 differentiation in Drosophila.

Ray M, Singh G, Lakhotia SC.

Gene Expr Patterns. 2019 Sep;33:20-36. doi: 10.1016/j.gep.2019.05.002. Epub 2019 May 13.

PMID:
31096022
4.

Amalaki Rasayana improved memory and neuronal metabolic activity in AbPP-PS1 mouse model of Alzheimer's disease.

Tiwari V, Saba K, Veeraiah P, Jose J, Lakhotia SC, Patel AB.

J Biosci. 2017 Sep;42(3):363-371.

5.

Energetics of Excitatory and Inhibitory Neurotransmission in Aluminum Chloride Model of Alzheimer's Disease: Reversal of Behavioral and Metabolic Deficits by Rasa Sindoor.

Saba K, Rajnala N, Veeraiah P, Tiwari V, Rana RK, Lakhotia SC, Patel AB.

Front Mol Neurosci. 2017 Oct 17;10:323. doi: 10.3389/fnmol.2017.00323. eCollection 2017.

6.

From Heterochromatin to Long Noncoding RNAs in Drosophila: Expanding the Arena of Gene Function and Regulation.

Lakhotia SC.

Adv Exp Med Biol. 2017;1008:75-118. doi: 10.1007/978-981-10-5203-3_3. Review.

PMID:
28815537
8.

Azadiradione ameliorates polyglutamine expansion disease in Drosophila by potentiating DNA binding activity of heat shock factor 1.

Nelson VK, Ali A, Dutta N, Ghosh S, Jana M, Ganguli A, Komarov A, Paul S, Dwivedi V, Chatterjee S, Jana NR, Lakhotia SC, Chakrabarti G, Misra AK, Mandal SC, Pal M.

Oncotarget. 2016 Nov 29;7(48):78281-78296. doi: 10.18632/oncotarget.12930.

10.

Erratum to: Expression of hsrω-RNAi transgene prior to heat shock specifically compromises accumulation of heat shock-induced Hsp70 in Drosophila melanogaster.

Singh AK, Lakhotia SC.

Cell Stress Chaperones. 2016 Jan;21(1):121. doi: 10.1007/s12192-015-0649-1. No abstract available.

12.

Expression of hsrω-RNAi transgene prior to heat shock specifically compromises accumulation of heat shock-induced Hsp70 in Drosophila melanogaster.

Singh AK, Lakhotia SC.

Cell Stress Chaperones. 2016 Jan;21(1):105-120. doi: 10.1007/s12192-015-0644-6. Epub 2015 Sep 19. Erratum in: Cell Stress Chaperones. 2015 Oct 20.DOI: 10.1007/s12192-015-0649-1. Cell Stress Chaperones. 2015 Oct 20;:.

13.

The hnRNP A1 homolog Hrb87F/Hrp36 is important for telomere maintenance in Drosophila melanogaster.

Singh AK, Lakhotia SC.

Chromosoma. 2016 Jun;125(3):373-88. doi: 10.1007/s00412-015-0540-y. Epub 2015 Sep 16.

PMID:
26373285
14.

excellence in medical research - can we make it in india?

Lakhotia SC, Anand A.

Ann Neurosci. 2015 Apr;22(2):55-7. doi: 10.5214/ans.0972.7531.220201. No abstract available.

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Dynamics of hnRNPs and omega speckles in normal and heat shocked live cell nuclei of Drosophila melanogaster.

Singh AK, Lakhotia SC.

Chromosoma. 2015 Sep;124(3):367-83. doi: 10.1007/s00412-015-0506-0. Epub 2015 Feb 8.

PMID:
25663367
17.

Translating Ayurveda's Dosha-Prakriti into objective parameters.

Lakhotia SC.

J Ayurveda Integr Med. 2014 Jul;5(3):176. No abstract available.

18.

Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment.

Kumar A, Singh PK, Parihar R, Dwivedi V, Lakhotia SC, Ganesh S.

J Biol Chem. 2014 May 9;289(19):13543-53. doi: 10.1074/jbc.M114.553321. Epub 2014 Mar 19.

19.

Neurodegeneration disorders need holistic care and treatment - can ayurveda meet the challenge?

Lakhotia SC.

Ann Neurosci. 2013 Jan;20(1):1-2. doi: 10.5214/ans.0972.7531.200101. No abstract available.

20.

Dysregulation of core components of SCF complex in poly-glutamine disorders.

Bhutani S, Das A, Maheshwari M, Lakhotia SC, Jana NR.

Cell Death Dis. 2012 Nov 22;3:e428. doi: 10.1038/cddis.2012.166.

21.

Long non-coding RNAs coordinate cellular responses to stress.

Lakhotia SC.

Wiley Interdiscip Rev RNA. 2012 Nov-Dec;3(6):779-96. doi: 10.1002/wrna.1135. Epub 2012 Sep 13. Review.

PMID:
22976942
23.

In vivo effects of traditional Ayurvedic formulations in Drosophila melanogaster model relate with therapeutic applications.

Dwivedi V, Anandan EM, Mony RS, Muraleedharan TS, Valiathan MS, Mutsuddi M, Lakhotia SC.

PLoS One. 2012;7(5):e37113. doi: 10.1371/journal.pone.0037113. Epub 2012 May 14.

24.

The large noncoding hsrω-n transcripts are essential for thermotolerance and remobilization of hnRNPs, HP1 and RNA polymerase II during recovery from heat shock in Drosophila.

Lakhotia SC, Mallik M, Singh AK, Ray M.

Chromosoma. 2012 Feb;121(1):49-70. doi: 10.1007/s00412-011-0341-x. Epub 2011 Sep 9. Erratum in: Chromosoma. 2012 Feb;121(1):105-6.

PMID:
21913129
25.

DNApol-ϵ gene is indispensable for the survival and growth of Drosophila melanogaster.

Verma A, Sengupta S, Lakhotia SC.

Genesis. 2012 Feb;50(2):86-101. doi: 10.1002/dvg.20791. Epub 2011 Oct 19.

PMID:
21898761
26.

Forty years of the 93D puff of Drosophila melanogaster.

Lakhotia SC.

J Biosci. 2011 Aug;36(3):399-423. Review.

28.

The ISWI chromatin remodeler organizes the hsrω ncRNA-containing omega speckle nuclear compartments.

Onorati MC, Lazzaro S, Mallik M, Ingrassia AM, Carreca AP, Singh AK, Chaturvedi DP, Lakhotia SC, Corona DF.

PLoS Genet. 2011 May;7(5):e1002096. doi: 10.1371/journal.pgen.1002096. Epub 2011 May 26.

29.

Validation of Ayurvedic formulations in animal models requires stringent scientific rigor.

Lakhotia SC.

J Ayurveda Integr Med. 2010 Jul;1(3):171-2. doi: 10.4103/0975-9476.72607. No abstract available.

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Nature of methods in science: technology driven science versus science driven technology.

Lakhotia SC.

Bioessays. 2009 Dec;31(12):1370-1. doi: 10.1002/bies.200900144. No abstract available.

PMID:
19921664
33.

The developmentally active and stress-inducible noncoding hsromega gene is a novel regulator of apoptosis in Drosophila.

Mallik M, Lakhotia SC.

Genetics. 2009 Nov;183(3):831-52. doi: 10.1534/genetics.109.108571. Epub 2009 Sep 7.

34.

RNAi for the large non-coding hsromega transcripts suppresses polyglutamine pathogenesis in Drosophila models.

Mallik M, Lakhotia SC.

RNA Biol. 2009 Sep-Oct;6(4):464-78. Epub 2009 Sep 17.

PMID:
19667761
35.
36.

Hsp60D is essential for caspase-mediated induced apoptosis in Drosophila melanogaster.

Arya R, Lakhotia SC.

Cell Stress Chaperones. 2008 Dec;13(4):509-26. doi: 10.1007/s12192-008-0051-3. Epub 2008 May 28.

37.

Hsp60C is required in follicle as well as germline cells during oogenesis in Drosophila melanogaster.

Sarkar S, Lakhotia SC.

Dev Dyn. 2008 May;237(5):1334-47. doi: 10.1002/dvdy.21524.

38.

Perils of "industrial gene" and "beanbag genetics".

Lakhotia SC.

Bioessays. 2008 Mar;30(3):288. doi: 10.1002/bies.20727. No abstract available.

PMID:
18293374
39.

Heat shock genes - integrating cell survival and death.

Arya R, Mallik M, Lakhotia SC.

J Biosci. 2007 Apr;32(3):595-610. Review.

40.

Altered expressions of the noncoding hsromega gene enhances poly-Q-induced neurotoxicity in Drosophila.

Sengupta S, Lakhotia SC.

RNA Biol. 2006 Jan-Mar;3(1):28-35. Epub 2006 Feb 1.

PMID:
17114940
41.

Human sat III and Drosophila hsr omega transcripts: a common paradigm for regulation of nuclear RNA processing in stressed cells.

Jolly C, Lakhotia SC.

Nucleic Acids Res. 2006;34(19):5508-14. Epub 2006 Oct 4. Review. Erratum in: Nucleic Acids Res. 2007;35(8):2812.

44.

Epigenetics of heterochromatin.

Lakhotia SC.

J Biosci. 2004 Sep;29(3):219-24. No abstract available.

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Tissue-specific variations in the induction of Hsp70 and Hsp64 by heat shock in insects.

Singh AK, Lakhotia SC.

Cell Stress Chaperones. 2000 Apr;5(2):90-7.

50.

Omega speckles - a novel class of nuclear speckles containing hnRNPs associated with noncoding hsr-omega RNA in Drosophila.

Prasanth KV, Rajendra TK, Lal AK, Lakhotia SC.

J Cell Sci. 2000 Oct;113 Pt 19:3485-97.

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