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Items: 28


A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation.

Bery N, Keller L, Soulié M, Gence R, Iscache AL, Cherier J, Cabantous S, Sordet O, Lajoie-Mazenc I, Pedelacq JD, Favre G, Olichon A.

Cell Chem Biol. 2019 Nov 21;26(11):1544-1558.e6. doi: 10.1016/j.chembiol.2019.08.009. Epub 2019 Sep 12.


High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation.

Koraïchi F, Gence R, Bouchenot C, Grosjean S, Lajoie-Mazenc I, Favre G, Cabantous S.

J Cell Sci. 2018 Jan 8;131(1). pii: jcs210419. doi: 10.1242/jcs.210419.


In vivo Effects in Melanoma of ROCK Inhibition-Induced FasL Overexpression.

Teiti I, Florie B, Pich C, Gence R, Lajoie-Mazenc I, Rochaix P, Favre G, Tilkin-Mariamé AF.

Front Oncol. 2015 Jul 14;5:156. doi: 10.3389/fonc.2015.00156. eCollection 2015.


RhoB loss induces Rac1-dependent mesenchymal cell invasion in lung cells through PP2A inhibition.

Bousquet E, Calvayrac O, Mazières J, Lajoie-Mazenc I, Boubekeur N, Favre G, Pradines A.

Oncogene. 2016 Apr 7;35(14):1760-9. doi: 10.1038/onc.2015.240. Epub 2015 Jul 6.


Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma.

Bertrand F, Rochotte J, Colacios C, Montfort A, Tilkin-Mariamé AF, Touriol C, Rochaix P, Lajoie-Mazenc I, Andrieu-Abadie N, Levade T, Benoist H, Ségui B.

Cancer Res. 2015 Jul 1;75(13):2619-28. doi: 10.1158/0008-5472.CAN-14-2524. Epub 2015 May 14.


Generation of a single chain antibody variable fragment (scFv) to sense selectively RhoB activation.

Chinestra P, Olichon A, Medale-Giamarchi C, Lajoie-Mazenc I, Gence R, Inard C, Ligat L, Faye JC, Favre G.

PLoS One. 2014 Nov 3;9(11):e111034. doi: 10.1371/journal.pone.0111034. eCollection 2014.


RhoA and RhoC differentially modulate estrogen receptor α recruitment, transcriptional activities, and expression in breast cancer cells (MCF-7).

Malissein E, Meunier E, Lajoie-Mazenc I, Médale-Giamarchi C, Dalenc F, Doisneau-Sixou SF.

J Cancer Res Clin Oncol. 2013 Dec;139(12):2079-88. doi: 10.1007/s00432-013-1533-y. Epub 2013 Oct 6.


RhoB modifies estrogen responses in breast cancer cells by influencing expression of the estrogen receptor.

Médale-Giamarchi C, Lajoie-Mazenc I, Malissein E, Meunier E, Couderc B, Bergé Y, Filleron T, Keller L, Marty C, Lacroix-Triki M, Dalenc F, Doisneau-Sixou SF, Favre G.

Breast Cancer Res. 2013 Jan 22;15(1):R6. doi: 10.1186/bcr3377.


Use of phage display for the identification of molecular sensors specific for activated Rho.

Chinestra P, Lajoie-Mazenc I, Faye JC, Favre G.

Methods Mol Biol. 2012;827:283-303. doi: 10.1007/978-1-61779-442-1_19.


Phosphorylation of RhoB by CK1 impedes actin stress fiber organization and epidermal growth factor receptor stabilization.

Tillement V, Lajoie-Mazenc I, Casanova A, Froment C, Penary M, Tovar D, Marquez R, Monsarrat B, Favre G, Pradines A.

Exp Cell Res. 2008 Sep 10;314(15):2811-21. doi: 10.1016/j.yexcr.2008.06.011. Epub 2008 Jun 18.


Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection.

Goffinet M, Chinestra P, Lajoie-Mazenc I, Medale-Giamarchi C, Favre G, Faye JC.

BMC Biotechnol. 2008 Mar 31;8:34. doi: 10.1186/1472-6750-8-34.


MAP1A light chain-2 interacts with GTP-RhoB to control epidermal growth factor (EGF)-dependent EGF receptor signaling.

Lajoie-Mazenc I, Tovar D, Penary M, Lortal B, Allart S, Favard C, Brihoum M, Pradines A, Favre G.

J Biol Chem. 2008 Feb 15;283(7):4155-64. Epub 2007 Dec 3.


Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells.

Goffinet M, Thoulouzan M, Pradines A, Lajoie-Mazenc I, Weinbaum C, Faye JC, Séronie-Vivien S.

BMC Cancer. 2006 Mar 15;6:60.


Activation of RhoB by hypoxia controls hypoxia-inducible factor-1alpha stabilization through glycogen synthase kinase-3 in U87 glioblastoma cells.

Skuli N, Monferran S, Delmas C, Lajoie-Mazenc I, Favre G, Toulas C, Cohen-Jonathan-Moyal E.

Cancer Res. 2006 Jan 1;66(1):482-9.


RhoB protects human keratinocytes from UVB-induced apoptosis through epidermal growth factor receptor signaling.

Canguilhem B, Pradines A, Baudouin C, Boby C, Lajoie-Mazenc I, Charveron M, Favre G.

J Biol Chem. 2005 Dec 30;280(52):43257-63. Epub 2005 Nov 8.


Geranylgeranyl transferase inhibition stimulates anti-melanoma immune response through MHC Class I and costimulatory molecule expression.

Tilkin-Mariamé AF, Cormary C, Ferro N, Sarrabayrouse G, Lajoie-Mazenc I, Faye JC, Favre G.

FASEB J. 2005 Sep;19(11):1513-5. Epub 2005 Jun 29.


Farnesylated RhoB inhibits radiation-induced mitotic cell death and controls radiation-induced centrosome overduplication.

Milia J, Teyssier F, Dalenc F, Ader I, Delmas C, Pradines A, Lajoie-Mazenc I, Baron R, Bonnet J, Cohen-Jonathan E, Favre G, Toulas C.

Cell Death Differ. 2005 May;12(5):492-501.


RhoB prenylation is driven by the three carboxyl-terminal amino acids of the protein: evidenced in vivo by an anti-farnesyl cysteine antibody.

Baron R, Fourcade E, Lajoie-Mazenc I, Allal C, Couderc B, Barbaras R, Favre G, Faye JC, Pradines A.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11626-31.


RhoA prenylation is required for promotion of cell growth and transformation and cytoskeleton organization but not for induction of serum response element transcription.

Allal C, Favre G, Couderc B, Salicio S, Sixou S, Hamilton AD, Sebti SM, Lajoie-Mazenc I, Pradines A.

J Biol Chem. 2000 Oct 6;275(40):31001-8.


Activation of epithelial growth factor receptor pathway by unsaturated fatty acids.

Vacaresse N, Lajoie-Mazenc I, Augé N, Suc I, Frisach MF, Salvayre R, Nègre-Salvayre A.

Circ Res. 1999 Nov 12;85(10):892-9.


Condensation-decondensation of the gamma-tubulin containing material in the absence of a structurally visible organelle during the cell cycle of Physarum plasmodia.

Rotaru V, Lajoie-Mazenc I, Tollon Y, Raynaud-Messina B, Jean C, Détraves C, Julian M, Moisand A, Wright M.

Biol Cell. 1999 May-Jun;91(4-5):393-406.


Activation of EGF receptor by oxidized LDL.

Suc I, Meilhac O, Lajoie-Mazenc I, Vandaele J, Jürgens G, Salvayre R, Nègre-Salvayre A.

FASEB J. 1998 Jun;12(9):665-71.


Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein.

Augé N, Escargueil-Blanc I, Lajoie-Mazenc I, Suc I, Andrieu-Abadie N, Pieraggi MT, Chatelut M, Thiers JC, Jaffrézou JP, Laurent G, Levade T, Nègre-Salvayre A, Salvayre R.

J Biol Chem. 1998 May 22;273(21):12893-900.


Protein complexes containing gamma-tubulin are present in mammalian brain microtubule protein preparations.

Detraves C, Mazarguil H, Lajoie-Mazenc I, Julian M, Raynaud-Messina B, Wright M.

Cell Motil Cytoskeleton. 1997;36(2):179-89.


A single gamma-tubulin gene and mRNA, but two gamma-tubulin polypeptides differing by their binding to the spindle pole organizing centres.

Lajoie-Mazenc I, Détraves C, Rotaru V, Garès M, Tollon Y, Jean C, Julian M, Wright M, Raynaud-Messina B.

J Cell Sci. 1996 Oct;109 ( Pt 10):2483-92.


Recruitment of antigenic gamma-tubulin during mitosis in animal cells: presence of gamma-tubulin in the mitotic spindle.

Lajoie-Mazenc I, Tollon Y, Detraves C, Julian M, Moisand A, Gueth-Hallonet C, Debec A, Salles-Passador I, Puget A, Mazarguil H, et al.

J Cell Sci. 1994 Oct;107 ( Pt 10):2825-37.


gamma-Tubulin is present in acentriolar MTOCs during early mouse development.

Gueth-Hallonet C, Antony C, Aghion J, Santa-Maria A, Lajoie-Mazenc I, Wright M, Maro B.

J Cell Sci. 1993 May;105 ( Pt 1):157-66.


gamma-Tubulin participates in the formation of the midbody during cytokinesis in mammalian cells.

Julian M, Tollon Y, Lajoie-Mazenc I, Moisand A, Mazarguil H, Puget A, Wright M.

J Cell Sci. 1993 May;105 ( Pt 1):145-56.

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