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Items: 50

1.

Alterations of drug-metabolizing enzymes and transporters under diabetic conditions: what is the potential clinical significance?

Chen F, Li DY, Zhang B, Sun JY, Sun F, Ji X, Qiu JC, Parker RB, Laizure SC, Xu J.

Drug Metab Rev. 2018 Aug;50(3):369-397. doi: 10.1080/03602532.2018.1497645. Epub 2018 Sep 16.

PMID:
30221555
2.

Clinical implications of genetic variation in carboxylesterase drug metabolism.

Chen F, Zhang B, Parker RB, Laizure SC.

Expert Opin Drug Metab Toxicol. 2018 Feb;14(2):131-142. doi: 10.1080/17425255.2018.1420164. Epub 2018 Jan 4. Review.

PMID:
29264996
3.

Comparison of caffeine disposition following administration by oral solution (energy drink) and inspired powder (AeroShot) in human subjects.

Laizure SC, Meibohm B, Nelson K, Chen F, Hu ZY, Parker RB.

Br J Clin Pharmacol. 2017 Dec;83(12):2687-2694. doi: 10.1111/bcp.13389. Epub 2017 Sep 5.

4.

Simultaneous assay of multiple antibiotics in human plasma by LC-MS/MS: importance of optimizing formic acid concentration.

Chen F, Hu ZY, Laizure SC, Hudson JQ.

Bioanalysis. 2017 Mar;9(5):469-483. doi: 10.4155/bio-2016-0157. Epub 2017 Feb 8.

PMID:
28176533
5.

Measurement of caffeine and its three primary metabolites in human plasma by HPLC-ESI-MS/MS and clinical application.

Chen F, Hu ZY, Parker RB, Laizure SC.

Biomed Chromatogr. 2017 Jun;31(6). doi: 10.1002/bmc.3900. Epub 2017 Jan 4.

6.

Pharmacokinetics of Imipenem/Cilastatin Burn Intensive Care Unit Patients Undergoing High-Dose Continuous Venovenous Hemofiltration.

Boucher BA, Hudson JQ, Hill DM, Swanson JM, Wood GC, Laizure SC, Arnold-Ross A, Hu ZY, Hickerson WL.

Pharmacotherapy. 2016 Dec;36(12):1229-1237. doi: 10.1002/phar.1866. Epub 2016 Dec 4.

PMID:
27862103
7.

Effects of alcohol on human carboxylesterase drug metabolism.

Parker RB, Hu ZY, Meibohm B, Laizure SC.

Clin Pharmacokinet. 2015 Jun;54(6):627-38. doi: 10.1007/s40262-014-0226-2.

8.

Physiologically based pharmacokinetic modeling of impaired carboxylesterase-1 activity: effects on oseltamivir disposition.

Hu ZY, Edginton AN, Laizure SC, Parker RB.

Clin Pharmacokinet. 2014 Sep;53(9):825-36. doi: 10.1007/s40262-014-0160-3. Erratum in: Clin Pharmacokinet. 2014 Oct;53(10):959.

PMID:
25103325
9.

Identification of alcohol-dependent clopidogrel metabolites using conventional liquid chromatography/triple quadrupole mass spectrometry.

Hu ZY, Laizure SC, Herring VL, Parker RB.

Rapid Commun Mass Spectrom. 2014 Jun 15;28(11):1285-92. doi: 10.1002/rcm.6901.

10.

Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis.

Laizure SC, Parker RB, Herring VL, Hu ZY.

Drug Metab Dispos. 2014 Feb;42(2):201-6. doi: 10.1124/dmd.113.054353. Epub 2013 Nov 8.

12.

The role of human carboxylesterases in drug metabolism: have we overlooked their importance?

Laizure SC, Herring V, Hu Z, Witbrodt K, Parker RB.

Pharmacotherapy. 2013 Feb;33(2):210-22. doi: 10.1002/phar.1194. Review.

13.
15.

In vivo information-guided prediction approach for assessing the risks of drug-drug interactions associated with circulating inhibitory metabolites.

Hu ZY, Parker RB, Laizure SC.

Drug Metab Dispos. 2012 Aug;40(8):1487-94. doi: 10.1124/dmd.112.045799. Epub 2012 May 4.

16.

A comparison of the metabolism of clopidogrel and prasugrel.

Laizure SC, Parker RB.

Expert Opin Drug Metab Toxicol. 2010 Nov;6(11):1417-24. doi: 10.1517/17425255.2010.519334. Epub 2010 Sep 14. Review.

PMID:
20839914
17.

The effect of ethanol on oral cocaine pharmacokinetics reveals an unrecognized class of ethanol-mediated drug interactions.

Parker RB, Laizure SC.

Drug Metab Dispos. 2010 Feb;38(2):317-22. doi: 10.1124/dmd.109.030056. Epub 2009 Nov 17.

18.

Pharmacodynamic evaluation of the cardiovascular effects after the coadministration of cocaine and ethanol.

Laizure SC, Parker RB.

Drug Metab Dispos. 2009 Feb;37(2):310-4. doi: 10.1124/dmd.108.023531. Epub 2008 Nov 12.

19.

Pharmacokinetics of buprenorphine after intravenous administration in the mouse.

Yu S, Zhang X, Sun Y, Peng Y, Johnson J, Mandrell T, Shukla AJ, Laizure SC.

J Am Assoc Lab Anim Sci. 2006 May;45(3):12-6.

PMID:
16642964
20.

P-glycoprotein modulates aldosterone plasma disposition and tissue uptake.

Parker RB, Yates CR, Laizure SC, Weber KT.

J Cardiovasc Pharmacol. 2006 Jan;47(1):55-9.

PMID:
16424786
21.

Studies on itraconazole delivery and pharmacokinetics in mallard ducks (Anas platyrhynchos).

Tell LA, Craigmill AL, Clemons KV, Sun Y, Laizure SC, Clifford A, Ina JH, Nugent-Deal JP, Woods L, Stevens DA.

J Vet Pharmacol Ther. 2005 Jun;28(3):267-74.

PMID:
15953200
22.

Selective serotonin reuptake inhibitors for migraine prophylaxis.

Landy S, McGinnis J, Curlin D, Laizure SC.

Headache. 1999 Jan;39(1):28-32.

PMID:
15613191
23.

Effects of grapefruit juice on intestinal P-glycoprotein: evaluation using digoxin in humans.

Parker RB, Yates CR, Soberman JE, Laizure SC.

Pharmacotherapy. 2003 Aug;23(8):979-87.

PMID:
12921244
24.

Cocaethylene metabolism and interaction with cocaine and ethanol: role of carboxylesterases.

Laizure SC, Mandrell T, Gades NM, Parker RB.

Drug Metab Dispos. 2003 Jan;31(1):16-20.

PMID:
12485948
25.

Controlled release of oxytetracycline in sheep.

Sun Y, Peng Y, Aksornkoae N, Johnson JR, Boring JG, Scruggs D, Cooper RC, Laizure SC, Shukla AJ.

J Control Release. 2002 Dec 13;85(1-3):125-34.

PMID:
12480318
26.

Increased lithium dose requirement in a hyperglycemic patient.

Cyr M, Guia MA, Laizure SC.

Ann Pharmacother. 2002 Mar;36(3):427-9.

PMID:
11898805
27.

Disposition of morphine in tissues of the pregnant rat and foetus following single and continuous intraperitoneal administration to the mother.

DeVane CL, Simpkins JW, Boulton DW, Laizure SC, Miller RL.

J Pharm Pharmacol. 1999 Nov;51(11):1283-7.

PMID:
10632086
28.

Nefazodone: An update.

Laizure SC, Cyr M.

Int J Psychiatry Clin Pract. 2000;4(4):267-73. doi: 10.1080/13651500050517812.

PMID:
24926576
29.

Cocaethylene formation in rat, dog, and human hepatic microsomes.

Song N, Parker RB, Laizure SC.

Life Sci. 1999;64(23):2101-8.

PMID:
10372652
30.

Evaluation of dose-dependent pharmacokinetics of cocaethylene and cocaine in conscious dogs.

Parker RB, Laizure SC, Williams CL, Mandrell TD, Lima JJ.

Life Sci. 1998;62(4):333-42.

PMID:
9450505
31.

Decreased hypoprothrombinemic effect of warfarin associated with furosemide.

Laizure SC, Madlock L, Cyr M, Self T.

Ther Drug Monit. 1997 Jun;19(3):361-3.

PMID:
9200780
32.

Methazolamide-induced delirium.

Cyr M, Laizure SC, daCunha CM.

Pharmacotherapy. 1997 Mar-Apr;17(2):387-9.

PMID:
9085335
33.

Effects of ethanol and cocaethylene on cocaine pharmacokinetics in conscious dogs.

Parker RB, Williams CL, Laizure SC, Mandrell TD, LaBranche GS, Lima JJ.

Drug Metab Dispos. 1996 Aug;24(8):850-3.

PMID:
8869818
34.

Quantitation of cocaine and cocaethylene in canine serum by high-performance liquid chromatography.

Williams CL, Laizure SC, Parker RB, Lima JJ.

J Chromatogr B Biomed Appl. 1996 Jun 7;681(2):271-6.

PMID:
8811436
35.

Factors affecting serum protein binding of cocaine in humans.

Parker RB, Williams CL, Laizure SC, Lima JJ.

J Pharmacol Exp Ther. 1995 Nov;275(2):605-10.

PMID:
7473145
36.

Predominant pathway of cocaine metabolism unknown.

Laizure SC, Williams CL, Parker RB.

Am J Emerg Med. 1995 Mar;13(2):250. No abstract available.

PMID:
7893324
37.

Considerations in morphine therapy.

Laizure SC.

Am J Hosp Pharm. 1994 Aug 15;51(16):2042-3. Review. No abstract available.

PMID:
7977426
38.

Stability of ondansetron hydrochloride in syrups compounded from tablets.

Williams CL, Sanders PL, Laizure SC, Stevens RC, Fox JL, Hak LJ.

Am J Hosp Pharm. 1994 Mar 15;51(6):806-9. No abstract available.

PMID:
8010321
39.

Trimethoprim-sulfamethoxazole pharmacokinetics in trauma patients.

Hess MM, Boucher BA, Laizure SC, Stevens RC, Sanders PL, Janning SW, Croce MA, Fabian TC.

Pharmacotherapy. 1993 Nov-Dec;13(6):602-6.

PMID:
8302685
40.

The disposition and cerebrospinal fluid penetration of morphine and its two major glucuronidated metabolites in adults undergoing lumbar myelogram.

Laizure SC, Miller JH, Stevens RC, Donahue DJ, Laster RE, Brown D.

Pharmacotherapy. 1993 Sep-Oct;13(5):471-5.

PMID:
8247914
41.

Disposition of tirilazad (U74006F), a 21-aminosteroid, in the plasma, heart, brain, and liver of the rat.

Laizure SC, Franklin LK, Kaiser DG, Williams CL, Stevens RC, Sanders PL, Miller M.

Drug Metab Dispos. 1993 Sep-Oct;21(5):951-4.

PMID:
7902261
42.
43.

Pharmacokinetics and adverse effects of 20-mg/kg/day trimethoprim and 100-mg/kg/day sulfamethoxazole in healthy adult subjects.

Stevens RC, Laizure SC, Williams CL, Stein DS.

Antimicrob Agents Chemother. 1991 Sep;35(9):1884-90.

44.

Use of low-dose trimethoprim-sulfamethoxazole thrice weekly for primary and secondary prophylaxis of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients.

Stein DS, Stevens RC, Terry D, Laizure SC, Palte S, Lancaster DJ, Weems JJ, Williams CL.

Antimicrob Agents Chemother. 1991 Sep;35(9):1705-9.

45.

Disposition of bupropion in healthy volunteers and subjects with alcoholic liver disease.

DeVane CL, Laizure SC, Stewart JT, Kolts BE, Ryerson EG, Miller RL, Lai AA.

J Clin Psychopharmacol. 1990 Oct;10(5):328-32.

PMID:
2124217
46.
47.

Bupropion in depression. II. The role of metabolites in clinical outcome.

Golden RN, De Vane CL, Laizure SC, Rudorfer MV, Sherer MA, Potter WZ.

Arch Gen Psychiatry. 1988 Feb;45(2):145-9.

PMID:
3122699
48.
49.

Pharmacokinetics of bupropion and its major basic metabolites in normal subjects after a single dose.

Laizure SC, DeVane CL, Stewart JT, Dommisse CS, Lai AA.

Clin Pharmacol Ther. 1985 Nov;38(5):586-9.

PMID:
3931955
50.

Stability of bupropion and its major metabolites in human plasma.

Laizure SC, DeVane CL.

Ther Drug Monit. 1985;7(4):447-50.

PMID:
3936237

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