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Items: 1 to 50 of 141

1.

Characterization of New Zealand White Rabbit Gut-Associated Lymphoid Tissues and Use as Viral Oncology Animal Model.

Haines RA, Urbiztondo RA, Haynes RA 2nd, Simpson E, Niewiesk S, Lairmore MD.

ILAR J. 2016;57(1):34-43. doi: 10.1093/ilar/ilw004.

2.

Models of Virus-Induced Carcinogenesis and Oncolytic Viruses.

Lairmore MD, Niewiesk S.

ILAR J. 2016;57(1):1-2. doi: 10.1093/ilar/ilw003. No abstract available.

PMID:
27034389
3.

Animals Used in Research and Education, 1966-2016: Evolving Attitudes, Policies, and Relationships.

Lairmore MD, Ilkiw J.

J Vet Med Educ. 2015 Winter;42(5):425-40. doi: 10.3138/jvme.0615-087R.

PMID:
26673210
4.

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.

Romeo MM, Ko B, Kim J, Brady R, Heatley HC, He J, Harrod CK, Barnett B, Ratner L, Lairmore MD, Martinez E, Lüscher B, Robson CN, Henriksson M, Harrod R.

Virology. 2015 Feb;476:271-288. doi: 10.1016/j.virol.2014.12.008. Epub 2015 Jan 5.

5.

Animal models of bovine leukemia virus and human T-lymphotrophic virus type-1: insights in transmission and pathogenesis.

Lairmore MD.

Annu Rev Anim Biosci. 2014 Feb;2:189-208. doi: 10.1146/annurev-animal-022513-114117. Epub 2013 Dec 13. Review.

PMID:
25384140
6.

Naturally occurring diseases in animals: contributions to translational medicine.

Lairmore MD, Khanna C.

ILAR J. 2014;55(1):1-3. doi: 10.1093/ilar/ilu022. No abstract available.

PMID:
24936026
7.

Comparative host protein interactions with HTLV-1 p30 and HTLV-2 p28: insights into difference in pathobiology of human retroviruses.

Doueiri R, Anupam R, Kvaratskhelia M, Green KB, Lairmore MD, Green PL.

Retrovirology. 2012 Aug 9;9:64. doi: 10.1186/1742-4690-9-64.

8.

Mechanisms of human T-lymphotropic virus type 1 transmission and disease.

Lairmore MD, Haines R, Anupam R.

Curr Opin Virol. 2012 Aug;2(4):474-81. doi: 10.1016/j.coviro.2012.06.007. Epub 2012 Jul 20. Review.

PMID:
22819021
9.

Distinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansion.

Kannian P, Yin H, Doueiri R, Lairmore MD, Fernandez S, Green PL.

J Virol. 2012 Apr;86(7):3757-66. doi: 10.1128/JVI.06900-11. Epub 2012 Jan 25.

10.

Recombinant human T-cell leukemia virus types 1 and 2 Tax proteins induce high levels of CC-chemokines and downregulate CCR5 in human peripheral blood mononuclear cells.

Barrios CS, Abuerreish M, Lairmore MD, Castillo L, Giam CZ, Beilke MA.

Viral Immunol. 2011 Dec;24(6):429-39. doi: 10.1089/vim.2011.0037. Epub 2011 Nov 23.

11.

Conference highlights of the 15th International Conference on Human Retrovirology: HTLV and related retroviruses, 4-8 June 2011, Leuven, Gembloux, Belgium.

Martin F, Bangham CR, Ciminale V, Lairmore MD, Murphy EL, Switzer WM, Mahieux R.

Retrovirology. 2011 Oct 28;8:86. doi: 10.1186/1742-4690-8-86.

12.

Molecular determinants of human T-lymphotropic virus type 1 transmission and spread.

Lairmore MD, Anupam R, Bowden N, Haines R, Haynes RA 2nd, Ratner L, Green PL.

Viruses. 2011 Jul;3(7):1131-65. doi: 10.3390/v3071131. Epub 2011 Jul 12. Review.

13.

Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.

Zimmerman B, Sargeant A, Landes K, Fernandez SA, Chen CS, Lairmore MD.

Leuk Res. 2011 Nov;35(11):1491-7. doi: 10.1016/j.leukres.2011.07.015. Epub 2011 Jul 29.

14.

Advancing translational research.

Bolon B, Altrock B, Barthold SW, Baumgarth N, Besselsen D, Boivin G, Boyd KL, Brayton C, Cardiff RD, Couto S, Eaton KA, Foreman O, Griffey SM, La Perle K, Lairmore MD, Liu C, Meyerholz DK, Nikitin AY, Schoeb TR, Schwahn D, Sellers RS, Sundberg JP, Tolwani R, Valli VE, Zink MC.

Science. 2011 Mar 25;331(6024):1516-7. doi: 10.1126/science.331.6024.1516-b. No abstract available.

PMID:
21436422
15.

Human T-lymphotropic virus type 1 p30 interacts with REGgamma and modulates ATM (ataxia telangiectasia mutated) to promote cell survival.

Anupam R, Datta A, Kesic M, Green-Church K, Shkriabai N, Kvaratskhelia M, Lairmore MD.

J Biol Chem. 2011 Mar 4;286(9):7661-8. doi: 10.1074/jbc.M110.176354. Epub 2011 Jan 7.

16.

The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.

Rauch DA, Hurchla MA, Harding JC, Deng H, Shea LK, Eagleton MC, Niewiesk S, Lairmore MD, Piwnica-Worms D, Rosol TJ, Weber JD, Ratner L, Weilbaecher KN.

PLoS One. 2010 Dec 30;5(12):e15755. doi: 10.1371/journal.pone.0015755.

17.

Mouse models of human T lymphotropic virus type-1-associated adult T-cell leukemia/lymphoma.

Zimmerman B, Niewiesk S, Lairmore MD.

Vet Pathol. 2010 Jul;47(4):677-89. doi: 10.1177/0300985810370009. Epub 2010 May 4.

18.

Early spatial and temporal events of human T-lymphotropic virus type 1 spread following blood-borne transmission in a rabbit model of infection.

Haynes RA 2nd, Zimmerman B, Millward L, Ware E, Premanandan C, Yu L, Phipps AJ, Lairmore MD.

J Virol. 2010 May;84(10):5124-30. doi: 10.1128/JVI.01537-09. Epub 2010 Mar 10.

19.

Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.

Banerjee P, Tripp A, Lairmore MD, Crawford L, Sieburg M, Ramos JC, Harrington W Jr, Beilke MA, Feuer G.

Blood. 2010 Apr 1;115(13):2640-8. doi: 10.1182/blood-2009-10-246959. Epub 2010 Feb 1. Retraction in: Blood. 2014 Jul 10;124(2):305.

20.

Cyclosporine-induced immune suppression alters establishment of HTLV-1 infection in a rabbit model.

Haynes RA 2nd, Ware E, Premanandan C, Zimmerman B, Yu L, Phipps AJ, Lairmore MD.

Blood. 2010 Jan 28;115(4):815-23. doi: 10.1182/blood-2009-07-230912. Epub 2009 Nov 20.

21.

Development of a cytotoxic T-cell assay in rabbits to evaluate early immune response to human T-lymphotropic virus type 1 infection.

Haynes RA 2nd, Phipps AJ, Yamamoto B, Green P, Lairmore MD.

Viral Immunol. 2009 Dec;22(6):397-405. doi: 10.1089/vim.2009.0059.

22.

The need for veterinarians in biomedical research.

Rosol TJ, Moore RM, Saville WJ, Oglesbee MJ, Rush LJ, Mathes LE, Lairmore MD.

J Vet Med Educ. 2009 Spring;36(1):70-5. doi: 10.3138/jvme.36.1.70. Review.

23.

Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages.

Premanandan C, Storozuk CA, Clay CD, Lairmore MD, Schlesinger LS, Phipps AJ.

Microb Pathog. 2009 Jun;46(6):306-14. doi: 10.1016/j.micpath.2009.03.004. Epub 2009 Mar 27.

PMID:
19328844
24.

Human T-cell leukemia virus type 2 Rex carboxy terminus is an inhibitory/stability domain that regulates Rex functional activity and viral replication.

Xie L, Kesic M, Yamamoto B, Li M, Younis I, Lairmore MD, Green PL.

J Virol. 2009 May;83(10):5232-43. doi: 10.1128/JVI.02271-08. Epub 2009 Mar 11.

25.

Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation.

Arnold J, Zimmerman B, Li M, Lairmore MD, Green PL.

Blood. 2008 Nov 1;112(9):3788-97. doi: 10.1182/blood-2008-04-154286. Epub 2008 Aug 8.

26.

XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from molecular pathogenesis to targeted therapy in leukemia and solid tumors.

Hackanson B, Becker H, Berg T, Binder M, Dierks C, Duque-Afonso J, Lairmore MD, Schäfer HS, Schnitzler M, Zeiser R, Martens U, Mertelsmann R, Lübbert M.

Cancer Res. 2008 Jul 15;68(14):5512-8. doi: 10.1158/0008-5472.CAN-07-6859. No abstract available.

27.

Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation.

Nadella MV, Shu ST, Dirksen WP, Thudi NK, Nadella KS, Fernandez SA, Lairmore MD, Green PL, Rosol TJ.

Retrovirology. 2008 Jun 9;5:46. doi: 10.1186/1742-4690-5-46.

28.

Human T-cell leukemia virus type 2 post-transcriptional control protein p28 is required for viral infectivity and persistence in vivo.

Yamamoto B, Li M, Kesic M, Younis I, Lairmore MD, Green PL.

Retrovirology. 2008 May 12;5:38. doi: 10.1186/1742-4690-5-38.

29.

Developing and fostering a dynamic program for training in veterinary pathology and clinical pathology: veterinary students to post-graduate education.

Lairmore MD, Oglesbee M, Weisbrode SE, Wellman M, Rosol T, Stromberg P.

J Vet Med Educ. 2007 Fall;34(4):464-72. doi: 10.3138/jvme.34.4.464.

30.

A novel bioluminescent mouse model and effective therapy for adult T-cell leukemia/lymphoma.

Shu ST, Nadella MV, Dirksen WP, Fernandez SA, Thudi NK, Werbeck JL, Lairmore MD, Rosol TJ.

Cancer Res. 2007 Dec 15;67(24):11859-66.

31.

Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival.

Datta A, Silverman L, Phipps AJ, Hiraragi H, Ratner L, Lairmore MD.

Retrovirology. 2007 Jul 16;4:49.

32.

Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity.

Michael B, Nair AM, Datta A, Hiraragi H, Ratner L, Lairmore MD.

Virology. 2006 Oct 25;354(2):225-39. Epub 2006 Aug 4.

33.

Quantitative measurement of anthrax toxin receptor messenger RNA in primary mononuclear phagocytes.

Premanandan C, Lairmore MD, Fernandez S, Phipps AJ.

Microb Pathog. 2006 Oct-Nov;41(4-5):193-8. Epub 2006 Jul 18.

PMID:
16854559
34.

Calcium-dependent enhancement of transcription of p300 by human T-lymphotropic type 1 p12I.

Nair AM, Michael B, Datta A, Fernandez S, Lairmore MD.

Virology. 2006 Sep 30;353(2):247-57. Epub 2006 Jul 14.

35.

Enhancement of LFA-1-mediated T cell adhesion by human T lymphotropic virus type 1 p12I1.

Kim SJ, Nair AM, Fernandez S, Mathes L, Lairmore MD.

J Immunol. 2006 May 1;176(9):5463-70.

36.

Human T-lymphotropic virus type 1 mitochondrion-localizing protein p13(II) is required for viral infectivity in vivo.

Hiraragi H, Kim SJ, Phipps AJ, Silic-Benussi M, Ciminale V, Ratner L, Green PL, Lairmore MD.

J Virol. 2006 Apr;80(7):3469-76.

37.

Coordinate enhancement of transgene transcription and translation in a lentiviral vector.

Yilmaz A, Fernandez S, Lairmore MD, Boris-Lawrie K.

Retrovirology. 2006 Feb 15;3:13.

38.

Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1.

Arnold J, Yamamoto B, Li M, Phipps AJ, Younis I, Lairmore MD, Green PL.

Blood. 2006 May 15;107(10):3976-82. Epub 2006 Jan 19.

39.
40.

Animal models for human T-lymphotropic virus type 1 (HTLV-1) infection and transformation.

Lairmore MD, Silverman L, Ratner L.

Oncogene. 2005 Sep 5;24(39):6005-15. Review.

41.
42.

In vivo analysis of replication and immunogenicity of proviral clones of human T-lymphotropic virus type 1 with selective envelope surface-unit mutations.

Silverman LR, Phipps AJ, Montgomery A, Fernandez S, Tsukahara T, Ratner L, Lairmore MD.

Blood. 2005 Nov 15;106(10):3602-8. Epub 2005 Jul 26.

43.

Transcriptional regulation of parathyroid hormone-related protein promoter P3 by ETS-1 in adult T-cell leukemia/lymphoma.

Richard V, Nadella MV, Green PL, Lairmore MD, Feuer G, Foley JG, Rosol TJ.

Leukemia. 2005 Jul;19(7):1175-83.

44.

The human T-cell leukemia virus type 1 p13II protein: effects on mitochondrial function and cell growth.

D'Agostino DM, Silic-Benussi M, Hiraragi H, Lairmore MD, Ciminale V.

Cell Death Differ. 2005 Aug;12 Suppl 1:905-15. Review.

45.

Rabbit and nonhuman primate models of toxin-targeting human anthrax vaccines.

Phipps AJ, Premanandan C, Barnewall RE, Lairmore MD.

Microbiol Mol Biol Rev. 2004 Dec;68(4):617-29. Review.

46.

Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes.

Michael B, Nair AM, Hiraragi H, Shen L, Feuer G, Boris-Lawrie K, Lairmore MD.

Retrovirology. 2004 Nov 23;1:39.

47.

Long-term infection with retroviral structural gene vector provides protection against bovine leukemia virus disease in rabbits.

Altanerova V, Holicova D, Kucerova L, Altaner C, Lairmore MD, Boris-Lawrie K.

Virology. 2004 Nov 24;329(2):434-9.

48.

Repression of human T-cell leukemia virus type 1 and type 2 replication by a viral mRNA-encoded posttranscriptional regulator.

Younis I, Khair L, Dundr M, Lairmore MD, Franchini G, Green PL.

J Virol. 2004 Oct;78(20):11077-83.

49.
50.

Suppression of tumor growth and cell proliferation by p13II, a mitochondrial protein of human T cell leukemia virus type 1.

Silic-Benussi M, Cavallari I, Zorzan T, Rossi E, Hiraragi H, Rosato A, Horie K, Saggioro D, Lairmore MD, Willems L, Chieco-Bianchi L, D'Agostino DM, Ciminale V.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6629-34. Epub 2004 Apr 20.

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