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Development of Clinical Criteria for Functional Assessment to Predict Primary Nonfunction of High-Risk Livers Using Normothermic Machine Perfusion.

Mergental H, Stephenson BTF, Laing RW, Kirkham AJ, Neil DAH, Wallace LL, Boteon YL, Widmer J, Bhogal RH, Perera MTPR, Smith A, Reynolds GM, Yap C, Hübscher SG, Mirza DF, Afford SC.

Liver Transpl. 2018 Oct;24(10):1453-1469. doi: 10.1002/lt.25291.


UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences.

Matoušková P, Lecová L, Laing R, Dimunová D, Vogel H, Raisová Stuchlíková L, Nguyen LT, Kellerová P, Vokřál I, Lamka J, Szotáková B, Várady M, Skálová L.

Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):420-429. doi: 10.1016/j.ijpddr.2018.09.005. Epub 2018 Sep 26.


Cord Splitting Access to Ventral Intradural Cysts of Cervicothoracic Junction and Thoracic Spine.

Laing R, Timofeev I, Colasanti R, Dean A, Di Rienzo A.

World Neurosurg. 2018 Oct 5. pii: S1878-8750(18)32243-5. doi: 10.1016/j.wneu.2018.09.188. [Epub ahead of print]


Access to Antihypertensive Medicines at the Household Level: A Study From 8 Counties of Kenya.

Syed N, Rockers PC, Vian T, Onyango M, Laing RO, Wirtz VJ.

Glob Heart. 2018 Dec;13(4):247-253.e5. doi: 10.1016/j.gheart.2018.08.001. Epub 2018 Sep 20.


Perceptions of Kenyan adults on access to medicines for non-communicable diseases: A qualitative study.

Onyango MA, Vian T, Hirsch I, Salvi DD, Laing R, Rockers PC, Ashigbie PG, Wirtz VJ.

PLoS One. 2018 Aug 24;13(8):e0201917. doi: 10.1371/journal.pone.0201917. eCollection 2018.


Reducing hospital admissions for COPD: perspectives following the Christchurch Earthquake.

Epton M, Limber C, Gullery C, McGeoch G, Shand B, Laing R, Brokenshire S, Meads A, Nicholson-Hitt R.

BMJ Open Respir Res. 2018 Aug 2;5(1):e000286. doi: 10.1136/bmjresp-2018-000286. eCollection 2018.


Hidden in plain sight - Multiple resistant species within a strongyle community.

McIntyre J, Hamer K, Morrison AA, Bartley DJ, Sargison N, Devaney E, Laing R.

Vet Parasitol. 2018 Jul 15;258:79-87. doi: 10.1016/j.vetpar.2018.06.012. Epub 2018 Jun 11.


Combined Hypothermic and Normothermic Machine Perfusion Improves Functional Recovery of Extended Criteria Donor Livers.

Boteon YL, Laing RW, Schlegel A, Wallace L, Smith A, Attard J, Bhogal RH, Neil DAH, Hübscher S, Perera MTPR, Mirza DF, Afford SC, Mergental H.

Liver Transpl. 2018 Dec;24(12):1699-1715. doi: 10.1002/lt.25315.


Comparative analysis of essential medicines for cardiovascular diseases in countries of the WHO Eastern Mediterranean Region.

Mehrtash H, Laing R, Wirtz VJ.

East Mediterr Health J. 2018 Jul 17;24(5):427-434. doi: 10.26719/2018.24.5.427.


Equity in access to non-communicable disease medicines: a cross-sectional study in Kenya.

Rockers PC, Laing RO, Wirtz VJ.

BMJ Glob Health. 2018 Jun 22;3(3):e000828. doi: 10.1136/bmjgh-2018-000828. eCollection 2018. Erratum in: BMJ Glob Health. 2018 Aug 10;3(4):e000828corr1.


The impact of ileal pouch-anal anastomosis on graft survival following liver transplantation for primary sclerosing cholangitis.

Trivedi PJ, Reece J, Laing RW, Slaney E, Cooney R, Gunson BK, Kamarajah SK, Pinkney T, Thompson F, Muiesan P, Schlegel A, Hirschfield GM, Iqbal T, Ferguson J.

Aliment Pharmacol Ther. 2018 Aug;48(3):322-332. doi: 10.1111/apt.14828. Epub 2018 Jun 8.


Access to medicines for asthma, diabetes and hypertension in eight counties of Kenya.

Wirtz VJ, Turpin K, Laing RO, Mukiira CK, Rockers PC.

Trop Med Int Health. 2018 Aug;23(8):879-885. doi: 10.1111/tmi.13081. Epub 2018 Jun 14.


Access to asthma medicines at the household level in eight counties of Kenya.

Barakat D, Rockers PC, Vian T, Onyango MA, Laing RO, Wirtz VJ.

Int J Tuberc Lung Dis. 2018 May 1;22(5):585-590. doi: 10.5588/ijtld.17.0664.


Proof of concept: liver splitting during normothermic machine perfusion.

Stephenson BTF, Bonney GK, Laing RW, Bhogal RH, Marcon F, Neil DAH, Perera MTPR, Afford SC, Mergental H, Mirza DF.

J Surg Case Rep. 2018 Mar 28;2018(3):rjx218. doi: 10.1093/jscr/rjx218. eCollection 2018 Mar.


Low-dose-rate brachytherapy for the treatment of localised prostate cancer in men with a high risk of disease relapse.

Laing R, Uribe J, Uribe-Lewis S, Money-Kyrle J, Perna C, Chintzoglou S, Khaksar S, Langley SEM.

BJU Int. 2018 Oct;122(4):610-617. doi: 10.1111/bju.14223. Epub 2018 May 8.


Transcriptomic profiling of nematode parasites surviving vaccine exposure.

Sallé G, Laing R, Cotton JA, Maitland K, Martinelli A, Holroyd N, Tracey A, Berriman M, Smith WD, Newlands GFJ, Hanks E, Devaney E, Britton C.

Int J Parasitol. 2018 Apr;48(5):395-402. doi: 10.1016/j.ijpara.2018.01.004. Epub 2018 Mar 10.


Mechanisms of autophagy activation in endothelial cell and their targeting during normothermic machine liver perfusion.

Boteon YL, Laing R, Mergental H, Reynolds GM, Mirza DF, Afford SC, Bhogal RH.

World J Gastroenterol. 2017 Dec 28;23(48):8443-8451. doi: 10.3748/wjg.v23.i48.8443. Review.


A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.

Doyle SR, Laing R, Bartley DJ, Britton C, Chaudhry U, Gilleard JS, Holroyd N, Mable BK, Maitland K, Morrison AA, Tait A, Tracey A, Berriman M, Devaney E, Cotton JA, Sargison ND.

Genome Biol Evol. 2018 Feb 1;10(2):396-409. doi: 10.1093/gbe/evx269.


Analyzing implementation dynamics using theory-driven evaluation principles: lessons learnt from a South African centralized chronic dispensing model.

Magadzire BP, Marchal B, Mathys T, Laing RO, Ward K.

BMC Health Serv Res. 2017 Dec 4;17(Suppl 2):724. doi: 10.1186/s12913-017-2640-2.


Increased Expression of a MicroRNA Correlates with Anthelmintic Resistance in Parasitic Nematodes.

Gillan V, Maitland K, Laing R, Gu H, Marks ND, Winter AD, Bartley D, Morrison A, Skuce PJ, Rezansoff AM, Gilleard JS, Martinelli A, Britton C, Devaney E.

Front Cell Infect Microbiol. 2017 Nov 6;7:452. doi: 10.3389/fcimb.2017.00452. eCollection 2017.


Viability testing and transplantation of marginal livers (VITTAL) using normothermic machine perfusion: study protocol for an open-label, non-randomised, prospective, single-arm trial.

Laing RW, Mergental H, Yap C, Kirkham A, Whilku M, Barton D, Curbishley S, Boteon YL, Neil DA, Hübscher SG, Perera MTPR, Muiesan P, Isaac J, Roberts KJ, Cilliers H, Afford SC, Mirza DF.

BMJ Open. 2017 Nov 28;7(11):e017733. doi: 10.1136/bmjopen-2017-017733.


The UK DCD Risk Score: A new proposal to define futility in donation-after-circulatory-death liver transplantation.

Schlegel A, Kalisvaart M, Scalera I, Laing RW, Mergental H, Mirza DF, Perera T, Isaac J, Dutkowski P, Muiesan P.

J Hepatol. 2018 Mar;68(3):456-464. doi: 10.1016/j.jhep.2017.10.034. Epub 2017 Nov 15.


Comparative Analysis of Clinical Outcomes and Procedural Costs between the Conventional Two-stage Technique and 4D Brachytherapy for Early Prostate Cancer.

Langley SEM, Uribe J, Uribe-Lewis S, Money-Kyrle J, Perna C, Khaksar S, Soares R, Laing R.

Clin Oncol (R Coll Radiol). 2018 Jan;30(1):57-64. doi: 10.1016/j.clon.2017.09.006. Epub 2017 Oct 18.


Clinical outcomes of donation after circulatory death liver transplantation in primary sclerosing cholangitis.

Trivedi PJ, Scalera I, Slaney E, Laing RW, Gunson B, Hirschfield GM, Schlegel A, Ferguson J, Muiesan P.

J Hepatol. 2017 Nov;67(5):957-965. doi: 10.1016/j.jhep.2017.06.027. Epub 2017 Jul 8.


Long-term oncological outcomes and toxicity in 597 men aged ≤60 years at time of low-dose-rate brachytherapy for localised prostate cancer.

Langley SEM, Soares R, Uribe J, Uribe-Lewis S, Money-Kyrle J, Perna C, Khaksar S, Laing R.

BJU Int. 2018 Jan;121(1):38-45. doi: 10.1111/bju.13946. Epub 2017 Aug 2.


Accelerated versus standard epirubicin followed by cyclophosphamide, methotrexate, and fluorouracil or capecitabine as adjuvant therapy for breast cancer in the randomised UK TACT2 trial (CRUK/05/19): a multicentre, phase 3, open-label, randomised, controlled trial.

Cameron D, Morden JP, Canney P, Velikova G, Coleman R, Bartlett J, Agrawal R, Banerji J, Bertelli G, Bloomfield D, Brunt AM, Earl H, Ellis P, Gaunt C, Gillman A, Hearfield N, Laing R, Murray N, Couper N, Stein RC, Verrill M, Wardley A, Barrett-Lee P, Bliss JM; TACT2 Investigators.

Lancet Oncol. 2017 Jul;18(7):929-945. doi: 10.1016/S1470-2045(17)30404-7. Epub 2017 Jun 7.


A qualitative study of determinants of patient behaviour leading to an infection related hospital admission.

Tonna AP, Weidmann AE, Laing RB, Tonna I, Macartney GM, Paudyal V, Stewart D.

J R Coll Physicians Edinb. 2017 Mar;47(1):40-46. doi: 10.4997/JRCPE.2017.109.


The Use of an Acellular Oxygen Carrier in a Human Liver Model of Normothermic Machine Perfusion.

Laing RW, Bhogal RH, Wallace L, Boteon Y, Neil DAH, Smith A, Stephenson BTF, Schlegel A, Hübscher SG, Mirza DF, Afford SC, Mergental H.

Transplantation. 2017 Nov;101(11):2746-2756. doi: 10.1097/TP.0000000000001821.


Industry-Led Access-To-Medicines Initiatives In Low- And Middle-Income Countries: Strategies And Evidence.

Rockers PC, Wirtz VJ, Umeh CA, Swamy PM, Laing RO.

Health Aff (Millwood). 2017 Apr 1;36(4):706-713. doi: 10.1377/hlthaff.2016.1213.


Normothermic ex-situ liver preservation: the new gold standard.

Laing RW, Mergental H, Mirza DF.

Curr Opin Organ Transplant. 2017 Jun;22(3):274-280. doi: 10.1097/MOT.0000000000000414. Review.


Ivermectin - Old Drug, New Tricks?

Laing R, Gillan V, Devaney E.

Trends Parasitol. 2017 Jun;33(6):463-472. doi: 10.1016/ Epub 2017 Mar 9. Review.


Baseline assessment of WHO's target for both availability and affordability of essential medicines to treat non-communicable diseases.

Ewen M, Zweekhorst M, Regeer B, Laing R.

PLoS One. 2017 Feb 7;12(2):e0171284. doi: 10.1371/journal.pone.0171284. eCollection 2017.


Prices and availability of locally produced and imported medicines in Ethiopia and Tanzania.

Ewen M, Kaplan W, Gedif T, Justin-Temu M, Vialle-Valentin C, Mirza Z, Regeer B, Zweekhorst M, Laing R.

J Pharm Policy Pract. 2017 Jan 16;10:7. doi: 10.1186/s40545-016-0095-1. eCollection 2017.


Study protocol for a cluster-randomised controlled trial of an NCD access to medicines initiative: evaluation of Novartis Access in Kenya.

Rockers PC, Wirtz VJ, Vian T, Onyango MA, Ashigbie PG, Laing R.

BMJ Open. 2016 Nov 25;6(11):e013386. doi: 10.1136/bmjopen-2016-013386.


Mass Spectrometry Based Metabolomics Comparison of Liver Grafts from Donors after Circulatory Death (DCD) and Donors after Brain Death (DBD) Used in Human Orthotopic Liver Transplantation.

Hrydziuszko O, Perera MT, Laing R, Kirwan J, Silva MA, Richards DA, Murphy N, Mirza DF, Viant MR.

PLoS One. 2016 Nov 11;11(11):e0165884. doi: 10.1371/journal.pone.0165884. eCollection 2016.


Hemi-gland focal low dose rate prostate brachytherapy: An analysis of dosimetric outcomes.

Laing R, Franklin A, Uribe J, Horton A, Uribe-Lewis S, Langley S.

Radiother Oncol. 2016 Nov;121(2):310-315. doi: 10.1016/j.radonc.2016.09.014. Epub 2016 Nov 1.


Transplantation of Declined Liver Allografts Following Normothermic Ex-Situ Evaluation.

Mergental H, Perera MT, Laing RW, Muiesan P, Isaac JR, Smith A, Stephenson BT, Cilliers H, Neil DA, Hübscher SG, Afford SC, Mirza DF.

Am J Transplant. 2016 Nov;16(11):3235-3245. doi: 10.1111/ajt.13875. Epub 2016 Jul 13.


The financial outcome of traumatic brain injury: a single centre study.

Fountain DM, Kolias AG, Laing RJ, Hutchinson PJ.

Br J Neurosurg. 2017 Jun;31(3):350-355. doi: 10.1080/02688697.2016.1244254. Epub 2016 Oct 22.


Response by Wirtz et al to Letter Regarding Article, "Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries".

Wirtz VJ, Kaplan WA, Kwan GF, Laing RO.

Circulation. 2016 Oct 4;134(14):e305-e306. No abstract available.


Creating the optimal workspace for hospital staff using human centred design.

Cawood T, Saunders E, Drennan C, Cross N, Nicholl D, Kenny A, Meates D, Laing R.

Intern Med J. 2016 Jul;46(7):840-5. doi: 10.1111/imj.13124.


Insulin in 2016: Challenge and constraints to access.

Beran D, Ewen M, Laing R.

Diabetes Res Clin Pract. 2016 Jul;117:119-21. doi: 10.1016/j.diabres.2016.06.001. No abstract available.


Haemonchus contortus: Genome Structure, Organization and Comparative Genomics.

Laing R, Martinelli A, Tracey A, Holroyd N, Gilleard JS, Cotton JA.

Adv Parasitol. 2016;93:569-98. doi: 10.1016/bs.apar.2016.02.016. Epub 2016 Apr 11. Review.


Access to Medications for Cardiovascular Diseases in Low- and Middle-Income Countries.

Wirtz VJ, Kaplan WA, Kwan GF, Laing RO.

Circulation. 2016 May 24;133(21):2076-85. doi: 10.1161/CIRCULATIONAHA.115.008722. Review.


Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in Haemonchus contortus.

Rezansoff AM, Laing R, Gilleard JS.

Int J Parasitol. 2016 Sep;46(10):653-61. doi: 10.1016/j.ijpara.2016.04.007. Epub 2016 May 20.


Analysis of putative resistance gene loci in UK field populations of Haemonchus contortus after 6years of macrocyclic lactone use.

Laing R, Maitland K, Lecová L, Skuce PJ, Tait A, Devaney E.

Int J Parasitol. 2016 Sep;46(10):621-30. doi: 10.1016/j.ijpara.2016.03.010. Epub 2016 May 11.


Evaluating availability and price of essential medicines in Boston area (Massachusetts, USA) using WHO/HAI methodology.

Sharma A, Rorden L, Ewen M, Laing R.

J Pharm Policy Pract. 2016 Apr 5;9:12. doi: 10.1186/s40545-016-0059-5. eCollection 2016.


Use of claims data to estimate annual cervical cancer screening percentages in Portland metropolitan area, Oregon.

Abdullah N, Laing RS, Hariri S, Young CM, Schafer S.

Cancer Epidemiol. 2016 Apr;41:106-12. doi: 10.1016/j.canep.2016.01.010. Epub 2016 Feb 18.


Constraints and challenges in access to insulin: a global perspective.

Beran D, Ewen M, Laing R.

Lancet Diabetes Endocrinol. 2016 Mar;4(3):275-285. doi: 10.1016/S2213-8587(15)00521-5. Epub 2016 Feb 6. Review.


Insulin patents and market exclusivities: unresolved issues.

Kaplan W, Laing R, Ewen M, Beran D.

Lancet Diabetes Endocrinol. 2016 Feb;4(2):98. doi: 10.1016/S2213-8587(15)00496-9. No abstract available.


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