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Items: 20


ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.

Guan T, Dominguez CX, Amezquita RA, Laidlaw BJ, Cheng J, Henao-Mejia J, Williams A, Flavell RA, Lu J, Kaech SM.

J Exp Med. 2018 Apr 2;215(4):1153-1168. doi: 10.1084/jem.20171352. Epub 2018 Feb 15.


Correction: STAT4 and T-bet control follicular helper T cell development in viral infections.

Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J.

J Exp Med. 2018 Mar 5;215(3):999. doi: 10.1084/jem.2017045702062018c. Epub 2018 Feb 13. No abstract available.


STAT4 and T-bet control follicular helper T cell development in viral infections.

Weinstein JS, Laidlaw BJ, Lu Y, Wang JK, Schulz VP, Li N, Herman EI, Kaech SM, Gallagher PG, Craft J.

J Exp Med. 2018 Jan 2;215(1):337-355. doi: 10.1084/jem.20170457. Epub 2017 Dec 6. Erratum in: J Exp Med. 2018 Feb 13;:.


Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response.

Laidlaw BJ, Lu Y, Amezquita RA, Weinstein JS, Vander Heiden JA, Gupta NT, Kleinstein SH, Kaech SM, Craft J.

Sci Immunol. 2017 Oct 20;2(16). pii: eaan4767. doi: 10.1126/sciimmunol.aan4767.


Interfer'n with antibody responses.

Laidlaw BJ, Cyster JG.

Sci Immunol. 2016 Oct 21;1(4). pii: eaaj1836. doi: 10.1126/sciimmunol.aaj1836. Review.


The Eph-related tyrosine kinase ligand Ephrin-B1 marks germinal center and memory precursor B cells.

Laidlaw BJ, Schmidt TH, Green JA, Allen CD, Okada T, Cyster JG.

J Exp Med. 2017 Mar 6;214(3):639-649. doi: 10.1084/jem.20161461. Epub 2017 Jan 31.


The multifaceted role of CD4(+) T cells in CD8(+) T cell memory.

Laidlaw BJ, Craft JE, Kaech SM.

Nat Rev Immunol. 2016 Feb;16(2):102-11. doi: 10.1038/nri.2015.10. Epub 2016 Jan 19. Review.


The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J.

Immunity. 2015 Oct 20;43(4):690-702. doi: 10.1016/j.immuni.2015.08.017. Epub 2015 Sep 22.


Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.

Laidlaw BJ, Cui W, Amezquita RA, Gray SM, Guan T, Lu Y, Kobayashi Y, Flavell RA, Kleinstein SH, Craft J, Kaech SM.

Nat Immunol. 2015 Aug;16(8):871-9. doi: 10.1038/ni.3224. Epub 2015 Jul 6.


The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa.

Marshall HD, Ray JP, Laidlaw BJ, Zhang N, Gawande D, Staron MM, Craft J, Kaech SM.

Elife. 2015 Jan 8;4:e04851. doi: 10.7554/eLife.04851.


A central role for Notch in effector CD8(+) T cell differentiation.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF, ten Brinke A, Willemsen AM, van Kampen AH, Kaech SM, Blander JM, van Gisbergen K, Amsen D.

Nat Immunol. 2014 Dec;15(12):1143-51. doi: 10.1038/ni.3027. Epub 2014 Oct 26.


CD4+ T cell help guides formation of CD103+ lung-resident memory CD8+ T cells during influenza viral infection.

Laidlaw BJ, Zhang N, Marshall HD, Staron MM, Guan T, Hu Y, Cauley LS, Craft J, Kaech SM.

Immunity. 2014 Oct 16;41(4):633-45. doi: 10.1016/j.immuni.2014.09.007. Epub 2014 Oct 9.


Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1.

Parish IA, Marshall HD, Staron MM, Lang PA, Brüstle A, Chen JH, Cui W, Tsui YC, Perry C, Laidlaw BJ, Ohashi PS, Weaver CT, Kaech SM.

J Clin Invest. 2014 Aug;124(8):3455-68. doi: 10.1172/JCI66108. Epub 2014 Jul 8.


Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells.

Ray JP, Marshall HD, Laidlaw BJ, Staron MM, Kaech SM, Craft J.

Immunity. 2014 Mar 20;40(3):367-77. doi: 10.1016/j.immuni.2014.02.005. Epub 2014 Mar 13.


CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity.

Kumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A.

Immunity. 2013 Oct 17;39(4):733-43. doi: 10.1016/j.immuni.2013.08.029. Epub 2013 Sep 26.


Cooperativity between CD8+ T cells, non-neutralizing antibodies, and alveolar macrophages is important for heterosubtypic influenza virus immunity.

Laidlaw BJ, Decman V, Ali MA, Abt MC, Wolf AI, Monticelli LA, Mozdzanowska K, Angelosanto JM, Artis D, Erikson J, Wherry EJ.

PLoS Pathog. 2013 Mar;9(3):e1003207. doi: 10.1371/journal.ppat.1003207. Epub 2013 Mar 14.


Defective CD8 T cell responses in aged mice are due to quantitative and qualitative changes in virus-specific precursors.

Decman V, Laidlaw BJ, Doering TA, Leng J, Ertl HC, Goldstein DR, Wherry EJ.

J Immunol. 2012 Feb 15;188(4):1933-41. doi: 10.4049/jimmunol.1101098. Epub 2012 Jan 13.


Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.

Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA, Angelosanto JM, Laidlaw BJ, Yang CY, Sathaliyawala T, Kubota M, Turner D, Diamond JM, Goldrath AW, Farber DL, Collman RG, Wherry EJ, Artis D.

Nat Immunol. 2011 Nov;12(11):1045-54. doi: 10.1031/ni.2131.


Cell-intrinsic defects in the proliferative response of antiviral memory CD8 T cells in aged mice upon secondary infection.

Decman V, Laidlaw BJ, Dimenna LJ, Abdulla S, Mozdzanowska K, Erikson J, Ertl HC, Wherry EJ.

J Immunol. 2010 May 1;184(9):5151-9. doi: 10.4049/jimmunol.0902063. Epub 2010 Apr 5.


Using intranasal lidocaine to reduce food intake.

Greenway FL, Martin CK, Gupta AK, Cruickshank S, Whitehouse J, DeYoung L, Kamdar K, Caruso MK, Roberts AT, England M, Dumas K, Laidlaw BJ, Rogers B, Cowley MA.

Int J Obes (Lond). 2007 May;31(5):858-63. Epub 2006 Nov 28.


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