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Items: 1 to 50 of 170


The Cervicovaginal Microbiota-Host Interaction Modulates Chlamydia trachomatis Infection.

Edwards VL, Smith SB, McComb EJ, Tamarelle J, Ma B, Humphrys MS, Gajer P, Gwilliam K, Schaefer AM, Lai SK, Terplan M, Mark KS, Brotman RM, Forney LJ, Bavoil PM, Ravel J.

MBio. 2019 Aug 13;10(4). pii: e01548-19. doi: 10.1128/mBio.01548-19.


Pretargeted delivery of PEG-coated drug carriers to breast tumors using multivalent, bispecific antibody against polyethylene glycol and HER2.

Parker CL, McSweeney MD, Lucas AT, Jacobs TM, Wadsworth D, Zamboni WC, Lai SK.

Nanomedicine. 2019 Aug 5:102076. doi: 10.1016/j.nano.2019.102076. [Epub ahead of print]


Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria.

Xu F, Newby JM, Schiller JL, Schroeder HA, Wessler T, Chen A, Forest MG, Lai SK.

ACS Infect Dis. 2019 Jul 3. doi: 10.1021/acsinfecdis.9b00109. [Epub ahead of print]


Robust antigen-specific tuning of the nanoscale barrier properties of biogels using matrix-associating IgG and IgM antibodies.

Schiller JL, Marvin A, McCallen JD, Lai SK.

Acta Biomater. 2019 Apr 15;89:95-103. doi: 10.1016/j.actbio.2019.03.023. Epub 2019 Mar 14.


Engineering Polymer-Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus-Covered Epithelium.

Huckaby JT, Parker CL, Jacobs TM, Schaefer A, Wadsworth D, Nguyen A, Wang A, Newby J, Lai SK.

Angew Chem Int Ed Engl. 2019 Apr 16;58(17):5604-5608. doi: 10.1002/anie.201814665. Epub 2019 Mar 21.


Plasmonic gold nanoparticles as multifaceted probe for tissue imaging.

Cheng YH, Tam TS, Chau SL, Lai SK, Tang HW, Lok CN, Lam CW, Ng KM.

Chem Commun (Camb). 2019 Feb 28;55(19):2761-2764. doi: 10.1039/c9cc00356h.


The impact of variations in obstetric practice on maternal birth trauma.

Kamisan Atan I, Lai SK, Langer S, Caudwell-Hall J, Dietz HP.

Int Urogynecol J. 2019 Jun;30(6):917-923. doi: 10.1007/s00192-019-03887-z. Epub 2019 Feb 11.


The phase separation underlying the pyrenoid-based microalgal Rubisco supercharger.

Wunder T, Cheng SLH, Lai SK, Li HY, Mueller-Cajar O.

Nat Commun. 2018 Nov 29;9(1):5076. doi: 10.1038/s41467-018-07624-w.


Live-Cell Imaging and Functional Dissection of Xist RNA Reveal Mechanisms of X Chromosome Inactivation and Reactivation.

Ha N, Lai LT, Chelliah R, Zhen Y, Yi Vanessa SP, Lai SK, Li HY, Ludwig A, Sandin S, Chen L, Zhang LF.

iScience. 2018 Oct 26;8:1-14. doi: 10.1016/j.isci.2018.09.007. Epub 2018 Sep 13.


Convolutional neural networks automate detection for tracking of submicron-scale particles in 2D and 3D.

Newby JM, Schaefer AM, Lee PT, Forest MG, Lai SK.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):9026-9031. doi: 10.1073/pnas.1804420115. Epub 2018 Aug 22.


Herpes simplex virus-binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition.

Schroeder HA, Nunn KL, Schaefer A, Henry CE, Lam F, Pauly MH, Whaley KJ, Zeitlin L, Humphrys MS, Ravel J, Lai SK.

Mucosal Immunol. 2018 Sep;11(5):1477-1486. doi: 10.1038/s41385-018-0054-z. Epub 2018 Jul 9.


A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse.

McSweeney MD, Wessler T, Price LSL, Ciociola EC, Herity LB, Piscitelli JA, Zamboni WC, Forest MG, Cao Y, Lai SK.

J Control Release. 2018 Aug 28;284:171-178. doi: 10.1016/j.jconrel.2018.06.002. Epub 2018 Jun 5.


ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus.

Yang B, Schaefer A, Wang YY, McCallen J, Lee P, Newby JM, Arora H, Kumar PA, Zeitlin L, Whaley KJ, McKinley SA, Fischer WA 2nd, Harit D, Lai SK.

J Infect Dis. 2018 Aug 14;218(6):901-910. doi: 10.1093/infdis/jiy230.


Wearable Activity Tracker Use Among Australian Adolescents: Usability and Acceptability Study.

Ridgers ND, Timperio A, Brown H, Ball K, Macfarlane S, Lai SK, Richards K, Mackintosh KA, McNarry MA, Foster M, Salmon J.

JMIR Mhealth Uhealth. 2018 Apr 11;6(4):e86. doi: 10.2196/mhealth.9199.


Accelerated Clearance of Ultrasound Contrast Agents Containing Polyethylene Glycol is Associated with the Generation of Anti-Polyethylene Glycol Antibodies.

Fix SM, Nyankima AG, McSweeney MD, Tsuruta JK, Lai SK, Dayton PA.

Ultrasound Med Biol. 2018 Jun;44(6):1266-1280. doi: 10.1016/j.ultrasmedbio.2018.02.006. Epub 2018 Mar 27.


Physician Awareness of Immune Responses to Polyethylene Glycol-Drug Conjugates.

McSweeney MD, Versfeld ZC, Carpenter DM, Lai SK.

Clin Transl Sci. 2018 Mar;11(2):162-165. doi: 10.1111/cts.12537. Epub 2018 Jan 31.


Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery.

Newby JM, Seim I, Lysy M, Ling Y, Huckaby J, Lai SK, Forest MG.

Adv Drug Deliv Rev. 2018 Jan 15;124:64-81. doi: 10.1016/j.addr.2017.12.002. Epub 2017 Dec 12. Review.


A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors.

Newby J, Schiller JL, Wessler T, Edelstein J, Forest MG, Lai SK.

Nat Commun. 2017 Oct 10;8(1):833. doi: 10.1038/s41467-017-00739-6.


PEGylation for enhancing nanoparticle diffusion in mucus.

Huckaby JT, Lai SK.

Adv Drug Deliv Rev. 2018 Jan 15;124:125-139. doi: 10.1016/j.addr.2017.08.010. Epub 2017 Sep 4. Review.


Multivalent interactions between streptavidin-based pretargeting fusion proteins and cell receptors impede efficient internalization of biotinylated nanoparticles.

Parker CL, Yang Q, Yang B, McCallen JD, Park SI, Lai SK.

Acta Biomater. 2017 Nov;63:181-189. doi: 10.1016/j.actbio.2017.08.049. Epub 2017 Sep 9.


Nonlinear wave propagation in porous materials based on the Biot theory.

Tong LH, Liu YS, Geng DX, Lai SK.

J Acoust Soc Am. 2017 Aug;142(2):756. doi: 10.1121/1.4996439.


Identification of a novel HLA-B allele, HLA-B*40:238, in a Taiwanese individual.

Lee HL, Lai SK, Chen PL, Chu CC.

HLA. 2017 Oct;90(4):252-253. doi: 10.1111/tan.13093. Epub 2017 Jul 31.


Broadband signal response of thermo-acoustic devices and its applications.

Tong LH, Lai SK, Lim CW.

J Acoust Soc Am. 2017 Apr;141(4):2430. doi: 10.1121/1.4979667.


P. falciparum RH5-Basigin interaction induces changes in the cytoskeleton of the host RBC.

Aniweh Y, Gao X, Hao P, Meng W, Lai SK, Gunalan K, Chu TT, Sinha A, Lescar J, Chandramohanadas R, Li HY, Sze SK, Preiser PR.

Cell Microbiol. 2017 Sep;19(9). doi: 10.1111/cmi.12747. Epub 2017 May 9.


Pretargeting with bispecific fusion proteins facilitates delivery of nanoparticles to tumor cells with distinct surface antigens.

Yang Q, Parker CL, Lin Y, Press OW, Park SI, Lai SK.

J Control Release. 2017 Jun 10;255:73-80. doi: 10.1016/j.jconrel.2017.03.388. Epub 2017 Mar 29.


Efficacy and safety of barbed suture in minimally invasive radical prostatectomy: A systematic review and meta-analysis.

Lin YF, Lai SK, Liu QY, Liao BH, Huang J, Du L, Wang KJ, Li H.

Kaohsiung J Med Sci. 2017 Mar;33(3):107-115. doi: 10.1016/j.kjms.2016.12.005. Epub 2017 Jan 27. Review.


Engineering Well-Characterized PEG-Coated Nanoparticles for Elucidating Biological Barriers to Drug Delivery.

Yang Q, Lai SK.

Methods Mol Biol. 2017;1530:125-137. doi: 10.1007/978-1-4939-6646-2_8.


Influenza-binding antibodies immobilise influenza viruses in fresh human airway mucus.

Wang YY, Harit D, Subramani DB, Arora H, Kumar PA, Lai SK.

Eur Respir J. 2017 Jan 25;49(1). pii: 1601709. doi: 10.1183/13993003.01709-2016. Print 2017 Jan. No abstract available.


A cluster-randomised controlled trial to promote physical activity in adolescents: the Raising Awareness of Physical Activity (RAW-PA) Study.

Ridgers ND, Timperio A, Brown H, Ball K, Macfarlane S, Lai SK, Richards K, Ngan W, Salmon J.

BMC Public Health. 2017 Jan 4;17(1):6. doi: 10.1186/s12889-016-3945-5.


The Young Innovators Program at the Eshelman Institute for Innovation: a case study examining the role of a professional pharmacy school in enhancing STEM pursuits among secondary school students.

Friedman AD, Melendez CR, Bush AA, Lai SK, McLaughlin JE.

Int J STEM Educ. 2017;4(1):17. doi: 10.1186/s40594-017-0081-4. Epub 2017 Sep 16.


Stereolithography-Based 3D Printed "Pillar Plates" that Minimizes Fluid Transfers During Enzyme Linked Immunosorbent Assays.

McCallen JD, Schaefer A, Lee P, Hing L, Lai SK.

Ann Biomed Eng. 2017 Apr;45(4):982-989. doi: 10.1007/s10439-016-1763-7. Epub 2016 Dec 2.


Solution-Processed MoS2 /Organolead Trihalide Perovskite Photodetectors.

Wang Y, Fullon R, Acerce M, Petoukhoff CE, Yang J, Chen C, Du S, Lai SK, Lau SP, Voiry D, O'Carroll D, Gupta G, Mohite AD, Zhang S, Zhou H, Chhowalla M.

Adv Mater. 2017 Jan;29(4). doi: 10.1002/adma.201603995. Epub 2016 Nov 21.


Analysis of Pre-existing IgG and IgM Antibodies against Polyethylene Glycol (PEG) in the General Population.

Yang Q, Jacobs TM, McCallen JD, Moore DT, Huckaby JT, Edelstein JN, Lai SK.

Anal Chem. 2016 Dec 6;88(23):11804-11812. Epub 2016 Nov 16.


Enhancement of Image Contrast, Stability, and SALDI-MS Detection Sensitivity for Latent Fingerprint Analysis by Tuning the Composition of Silver-Gold Nanoalloys.

Cheng YH, Zhang Y, Chau SL, Lai SK, Tang HW, Ng KM.

ACS Appl Mater Interfaces. 2016 Nov 2;8(43):29668-29675. Epub 2016 Oct 24.


Data on the effect of Cytopiloyne against Listeria monocytogenes infection in mice.

Chung CY, Yang WC, Liang CL, Liu HY, Lai SK, Chang CL.

Data Brief. 2016 Mar 17;7:995-998. eCollection 2016 Jun.


Mucus-Penetrating Nanosuspensions for Enhanced Delivery of Poorly Soluble Drugs to Mucosal Surfaces.

Yu T, Chisholm J, Choi WJ, Anonuevo A, Pulicare S, Zhong W, Chen M, Fridley C, Lai SK, Ensign LM, Suk JS, Hanes J.

Adv Healthc Mater. 2016 Nov;5(21):2745-2750. doi: 10.1002/adhm.201600599. Epub 2016 Sep 26.


The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors.

Miao L, Newby JM, Lin CM, Zhang L, Xu F, Kim WY, Forest MG, Lai SK, Milowsky MI, Wobker SE, Huang L.

ACS Nano. 2016 Oct 25;10(10):9243-9258. doi: 10.1021/acsnano.6b02776. Epub 2016 Sep 28.


Rough gold films as broadband absorbers for plasmonic enhancement of TiO2 photocurrent over 400-800 nm.

Tan F, Li T, Wang N, Lai SK, Tsoi CC, Yu W, Zhang X.

Sci Rep. 2016 Sep 9;6:33049. doi: 10.1038/srep33049.


Anti-PEG antibodies alter the mobility and biodistribution of densely PEGylated nanoparticles in mucus.

Henry CE, Wang YY, Yang Q, Hoang T, Chattopadhyay S, Hoen T, Ensign LM, Nunn KL, Schroeder H, McCallen J, Moench T, Cone R, Roffler SR, Lai SK.

Acta Biomater. 2016 Oct 1;43:61-70. doi: 10.1016/j.actbio.2016.07.019. Epub 2016 Jul 14.


Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus.

Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA.

PLoS One. 2016 Jun 30;11(6):e0158338. doi: 10.1371/journal.pone.0158338. eCollection 2016.


Aurora kinase-induced phosphorylation excludes transcription factor RUNX from the chromatin to facilitate proper mitotic progression.

Chuang LS, Khor JM, Lai SK, Garg S, Krishnan V, Koh CG, Lee SH, Ito Y.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6490-5. doi: 10.1073/pnas.1523157113. Epub 2016 May 23.


Shoot tolerance mechanisms to iron toxicity in rice (Oryza sativa L.).

Wu LB, Ueda Y, Lai SK, Frei M.

Plant Cell Environ. 2017 Apr;40(4):570-584. doi: 10.1111/pce.12733. Epub 2016 May 12.


Cytopiloyne, a polyacetylenic glucoside from Bidens pilosa, acts as a novel anticandidal agent via regulation of macrophages.

Chung CY, Yang WC, Liang CL, Liu HY, Lai SK, Chang CL.

J Ethnopharmacol. 2016 May 26;184:72-80. doi: 10.1016/j.jep.2016.02.036. Epub 2016 Feb 26.


Correlates of Gross Motor Competence in Children and Adolescents: A Systematic Review and Meta-Analysis.

Barnett LM, Lai SK, Veldman SLC, Hardy LL, Cliff DP, Morgan PJ, Zask A, Lubans DR, Shultz SP, Ridgers ND, Rush E, Brown HL, Okely AD.

Sports Med. 2016 Nov;46(11):1663-1688. doi: 10.1007/s40279-016-0495-z. Review.


Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus.

Wessler T, Chen A, McKinley SA, Cone R, Forest G, Lai SK.

ACS Infect Dis. 2016 Jan 8;2(1):82-92. Epub 2015 Oct 17.


Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue.

Shams F, Oldfield NJ, Lai SK, Tunio SA, Wooldridge KG, Turner DP.

Microbiologyopen. 2016 Apr;5(2):340-50. doi: 10.1002/mbo3.331. Epub 2016 Jan 5.


Minimizing biases associated with tracking analysis of submicron particles in heterogeneous biological fluids.

Wang YY, Nunn KL, Harit D, McKinley SA, Lai SK.

J Control Release. 2015 Dec 28;220(Pt A):37-43. doi: 10.1016/j.jconrel.2015.10.021. Epub 2015 Oct 18.


Enhanced Trapping of HIV-1 by Human Cervicovaginal Mucus Is Associated with Lactobacillus crispatus-Dominant Microbiota.

Nunn KL, Wang YY, Harit D, Humphrys MS, Ma B, Cone R, Ravel J, Lai SK.

MBio. 2015 Oct 6;6(5):e01084-15. doi: 10.1128/mBio.01084-15.

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