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Items: 1 to 50 of 108

1.

Effects of redox label location on the performance of an electrochemical aptamer-based tumor necrosis factor-alpha sensor.

Mayer MD, Lai RY.

Talanta. 2018 Nov 1;189:585-591. doi: 10.1016/j.talanta.2018.07.055. Epub 2018 Jul 18.

PMID:
30086964
2.

Highly Active C8-Acyl-ACP Thioesterase Variant Isolated by a Synthetic Selection Strategy.

Hernández Lozada NJ, Lai RY, Simmons TR, Thomas KA, Chowdhury R, Maranas CD, Pfleger BF.

ACS Synth Biol. 2018 Sep 21;7(9):2205-2215. doi: 10.1021/acssynbio.8b00215. Epub 2018 Aug 21.

PMID:
30064208
3.

Application of Calcium-Binding Motif of E-Cadherin for Electrochemical Detection of Pb(II).

Lotfi Zadeh Zhad HR, Lai RY.

Anal Chem. 2018 Jun 5;90(11):6519-6525. doi: 10.1021/acs.analchem.7b05458. Epub 2018 May 16.

PMID:
29767947
4.

Computational Redesign of Acyl-ACP Thioesterase with Improved Selectivity toward Medium-Chain-Length Fatty Acids.

Grisewood MJ, Hernandez Lozada NJ, Thoden JB, Gifford NP, Mendez-Perez D, Schoenberger HA, Allan MF, Floy ME, Lai RY, Holden HM, Pfleger BF, Maranas CD.

ACS Catal. 2017 Jun 2;7(6):3837-3849. doi: 10.1021/acscatal.7b00408. Epub 2017 Apr 20.

5.

Hexavalent Chromium as an Electrocatalyst in DNA Sensing.

Lotfi Zadeh Zhad HR, Lai RY.

Anal Chem. 2017 Dec 19;89(24):13342-13348. doi: 10.1021/acs.analchem.7b03514. Epub 2017 Dec 1.

PMID:
29143529
6.

A reagentless and reusable electrochemical aptamer-based sensor for rapid detection of ampicillin in complex samples.

Yu ZG, Lai RY.

Talanta. 2018 Jan 1;176:619-624. doi: 10.1016/j.talanta.2017.08.057. Epub 2017 Aug 19.

PMID:
28917799
7.

Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi.

Tempone AG, Ferreira DD, Lima ML, Costa Silva TA, Borborema SET, Reimão JQ, Galuppo MK, Guerra JM, Russell AJ, Wynne GM, Lai RYL, Cadelis MM, Copp BR.

Eur J Med Chem. 2017 Oct 20;139:947-960. doi: 10.1016/j.ejmech.2017.08.055. Epub 2017 Sep 1.

PMID:
28881289
8.

Tunable Signal-Off and Signal-On Electrochemical Cisplatin Sensor.

Wu Y, Lai RY.

Anal Chem. 2017 Sep 19;89(18):9984-9989. doi: 10.1021/acs.analchem.7b02353. Epub 2017 Aug 25.

PMID:
28799328
9.

Folding- and Dynamics-Based Electrochemical DNA Sensors.

Lai RY.

Methods Enzymol. 2017;589:221-252. doi: 10.1016/bs.mie.2017.02.001. Epub 2017 Mar 14.

PMID:
28336065
11.

Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease.

Lai RY, Harrington CR, Wischik CM.

Biomolecules. 2016 Apr 8;6(2). pii: E19. doi: 10.3390/biom6020019.

12.
13.

Electrochemical Gold(III) Sensor with High Sensitivity and Tunable Dynamic Range.

Wu Y, Lai RY.

Anal Chem. 2016 Feb 16;88(4):2227-33. doi: 10.1021/acs.analchem.5b03868. Epub 2016 Feb 2.

PMID:
26780489
14.

Electrochemical Detection of Platinum(IV) Prodrug Satraplatin in Serum.

Wu Y, Lai RY.

Anal Chem. 2015 Nov 3;87(21):11092-7. doi: 10.1021/acs.analchem.5b03215. Epub 2015 Oct 26.

PMID:
26465061
15.

Comparison of nanostructured silver-modified silver and carbon ultramicroelectrodes for electrochemical detection of nitrate.

Lotfi Zadeh Zhad HR, Lai RY.

Anal Chim Acta. 2015 Sep 10;892:153-9. doi: 10.1016/j.aca.2015.08.022. Epub 2015 Aug 22.

PMID:
26388486
16.

Incorporation of extra amino acids in peptide recognition probe to improve specificity and selectivity of an electrochemical peptide-based sensor.

Zaitouna AJ, Maben AJ, Lai RY.

Anal Chim Acta. 2015 Jul 30;886:157-64. doi: 10.1016/j.aca.2015.05.037. Epub 2015 Jul 7.

PMID:
26320648
17.

Comparison of Mannose, Ethylene Glycol, and Methoxy-Terminated Diluents on Specificity and Selectivity of Electrochemical Peptide-Based Sensors.

Zaitouna AJ, Joyce J, Cerny RL, Dussault PH, Lai RY.

Anal Chem. 2015 Jul 7;87(13):6966-73. doi: 10.1021/acs.analchem.5b01759. Epub 2015 Jun 22.

PMID:
26057465
18.

[Design and application of psychological intervention paths for ascites type of advanced schistosomiasis patients].

Lai RY, Shao ZW, Yu HQ, Li LL, Mei Y, He Y.

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2014 Dec;26(6):662-4. Chinese.

PMID:
25856895
19.

A randomized, placebo-controlled trial of the analgesic efficacy and safety of the p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain from lumbosacral radiculopathy.

Ostenfeld T, Krishen A, Lai RY, Bullman J, Green J, Anand P, Scholz J, Kelly M.

Clin J Pain. 2015 Apr;31(4):283-93. doi: 10.1097/AJP.0000000000000122.

PMID:
25751578
20.

Methylene blue-mediated electrocatalytic detection of hexavalent chromium.

Korshoj LE, Zaitouna AJ, Lai RY.

Anal Chem. 2015 Mar 3;87(5):2560-4. doi: 10.1021/acs.analchem.5b00197. Epub 2015 Feb 13.

PMID:
25671382
21.

Electrochemical hydrogen peroxide sensors fabricated using cytochrome c immobilized on macroelectrodes and ultramicroelectrodes.

Salamifar SE, Lee S, Lai RY.

Colloids Surf B Biointerfaces. 2014 Nov 1;123:866-9. doi: 10.1016/j.colsurfb.2014.10.033. Epub 2014 Oct 28.

PMID:
25454757
22.

Effects of DNA probe and target flexibility on the performance of a "signal-on" electrochemical DNA sensor.

Wu Y, Lai RY.

Anal Chem. 2014 Sep 2;86(17):8888-95. doi: 10.1021/ac5027226. Epub 2014 Aug 19.

PMID:
25110351
23.

Application of electrochemical surface plasmon resonance spectroscopy for characterization of electrochemical DNA sensors.

Salamifar SE, Lai RY.

Colloids Surf B Biointerfaces. 2014 Oct 1;122:835-839. doi: 10.1016/j.colsurfb.2014.07.028. Epub 2014 Jul 24.

PMID:
25096722
24.

A Hg(II)-mediated "signal-on" electrochemical glutathione sensor.

Lotfi Zadeh Zhad HR, Lai RY.

Chem Commun (Camb). 2014 Aug 7;50(61):8385-7. doi: 10.1039/c4cc03329a.

PMID:
24942852
25.

An electrochemical peptide-based Ara h 2 antibody sensor fabricated on a nickel(II)-nitriloacetic acid self-assembled monolayer using a His-tagged peptide.

Zaitouna AJ, Lai RY.

Anal Chim Acta. 2014 May 30;828:85-91. doi: 10.1016/j.aca.2014.04.033. Epub 2014 Apr 21.

PMID:
24845819
26.

Unexpectedly high affinity of a novel histamine H(3) receptor antagonist, GSK239512, in vivo in human brain, determined using PET.

Ashworth S, Berges A, Rabiner EA, Wilson AA, Comley RA, Lai RY, Boardley R, Searle G, Gunn RN, Laruelle M, Cunningham VJ.

Br J Pharmacol. 2014 Mar;171(5):1241-9. doi: 10.1111/bph.12505.

27.

Use of thiolated oligonucleotides as anti-fouling diluents in electrochemical peptide-based sensors.

McQuistan A, Zaitouna AJ, Echeverria E, Lai RY.

Chem Commun (Camb). 2014 May 11;50(36):4690-2. doi: 10.1039/c4cc01290a.

PMID:
24668223
28.

Fabrication of electrochemical DNA sensors on gold-modified recessed platinum nanoelectrodes.

Salamifar SE, Lai RY.

Anal Chem. 2014 Mar 18;86(6):2849-52. doi: 10.1021/ac403816h. Epub 2014 Feb 26.

PMID:
24559231
29.

Effect of redox label tether length and flexibility on sensor performance of displacement-based electrochemical DNA sensors.

Yu ZG, Zaitouna AJ, Lai RY.

Anal Chim Acta. 2014 Feb 17;812:176-83. doi: 10.1016/j.aca.2013.12.040. Epub 2014 Jan 9.

PMID:
24491779
30.

Characterization of an electrochemical mercury sensor using alternating current, cyclic, square wave and differential pulse voltammetry.

Guerreiro GV, Zaitouna AJ, Lai RY.

Anal Chim Acta. 2014 Jan 31;810:79-85. doi: 10.1016/j.aca.2013.12.005. Epub 2013 Dec 11.

PMID:
24439508
31.
32.

Use of combined scanning electrochemical and fluorescence microscopy for detection of reactive oxygen species in prostate cancer cells.

Salamifar SE, Lai RY.

Anal Chem. 2013 Oct 15;85(20):9417-21. doi: 10.1021/ac402367f. Epub 2013 Sep 26.

PMID:
24044675
33.

A whole-cell biosensor for the detection of gold.

Zammit CM, Quaranta D, Gibson S, Zaitouna AJ, Ta C, Brugger J, Lai RY, Grass G, Reith F.

PLoS One. 2013 Aug 9;8(8):e69292. doi: 10.1371/journal.pone.0069292. eCollection 2013.

34.

Electrochemical techniques for characterization of stem-loop probe and linear probe-based DNA sensors.

Lai RY, Walker B, Stormberg K, Zaitouna AJ, Yang W.

Methods. 2013 Dec 15;64(3):267-75. doi: 10.1016/j.ymeth.2013.07.041. Epub 2013 Aug 8.

PMID:
23933234
35.

Development of a "signal-on" electrochemical DNA sensor with an oligo-thymine spacer for point mutation detection.

Wu Y, Lai RY.

Chem Commun (Camb). 2013 Apr 28;49(33):3422-4. doi: 10.1039/c3cc41281d.

PMID:
23503676
36.

Effect of signaling probe conformation on sensor performance of a displacement-based electrochemical DNA sensor.

Yu ZG, Lai RY.

Anal Chem. 2013 Mar 19;85(6):3340-6. doi: 10.1021/ac3037987. Epub 2013 Mar 6.

PMID:
23413882
37.

Chemistry: a bridge to discovery.

Gross EM, Lai RY.

Bioanalysis. 2013 Jan;5(2):131-3. doi: 10.4155/bio.12.311.

38.

Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study.

Ostenfeld T, Krishen A, Lai RY, Bullman J, Baines AJ, Green J, Anand P, Kelly M.

Eur J Pain. 2013 Jul;17(6):844-57. doi: 10.1002/j.1532-2149.2012.00256.x. Epub 2012 Dec 14.

PMID:
23239139
39.

Development of an electrochemical insulin sensor based on the insulin-linked polymorphic region.

Gerasimov JY, Schaefer CS, Yang W, Grout RL, Lai RY.

Biosens Bioelectron. 2013 Apr 15;42:62-8. doi: 10.1016/j.bios.2012.10.046. Epub 2012 Oct 30.

PMID:
23202332
40.
41.

A dual-signalling electrochemical DNA sensor based on target hybridization-induced change in DNA probe flexibility.

Yang W, Lai RY.

Chem Commun (Camb). 2012 Sep 7;48(69):8703-5. doi: 10.1039/c2cc34312f. Epub 2012 Jul 24.

PMID:
22825042
42.

mRNA stability as a function of striated muscle oxidative capacity.

D'souza D, Lai RY, Shuen M, Hood DA.

Am J Physiol Regul Integr Comp Physiol. 2012 Aug 15;303(4):R408-17. doi: 10.1152/ajpregu.00085.2012. Epub 2012 Jun 20.

43.

Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate.

Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP.

J Am Chem Soc. 2012 Jun 6;134(22):9157-9. doi: 10.1021/ja302474a. Epub 2012 May 24.

44.

Combined optical and acoustical method for determination of thickness and porosity of transparent organic layers below the ultra-thin film limit.

Rodenhausen KB, Kasputis T, Pannier AK, Gerasimov JY, Lai RY, Solinsky M, Tiwald TE, Wang H, Sarkar A, Hofmann T, Ianno N, Schubert M.

Rev Sci Instrum. 2011 Oct;82(10):103111. doi: 10.1063/1.3653880.

PMID:
22047284
45.

Design and characterization of a metal ion-imidazole self-assembled monolayer for reversible immobilization of histidine-tagged peptides.

Zaitouna AJ, Lai RY.

Chem Commun (Camb). 2011 Dec 7;47(45):12391-3. doi: 10.1039/c1cc15510e. Epub 2011 Oct 21.

PMID:
22016887
46.

Comparison of the stem-loop and linear probe-based electrochemical DNA sensors by alternating current voltammetry and cyclic voltammetry.

Yang W, Lai RY.

Langmuir. 2011 Dec 6;27(23):14669-77. doi: 10.1021/la203015v. Epub 2011 Oct 28.

PMID:
21981414
47.

Application of synchrotron FTIR microspectroscopy for determination of spatial distribution of methylene blue conjugated onto a SAM via"click" chemistry.

Cañete SJ, Zhang Z, Kong L, Schlegel VL, Plantz BA, Dowben PA, Lai RY.

Chem Commun (Camb). 2011 Nov 21;47(43):11918-20. doi: 10.1039/c1cc13255e. Epub 2011 Oct 5.

PMID:
21975515
48.

Improvement in multifocal electroretinography after half-dose verteporfin photodynamic therapy for central serous chorioretinopathy: a randomized placebo-controlled trial.

Wu ZH, Lai RY, Yip YW, Chan WM, Lam DS, Lai TY.

Retina. 2011 Jul-Aug;31(7):1378-86. doi: 10.1097/FTD.0b013e31820beb02.

PMID:
21836413
49.

Design and characterization of an electrochemical peptide-based sensor fabricated via"click" chemistry.

Gerasimov JY, Lai RY.

Chem Commun (Camb). 2011 Aug 14;47(30):8688-90. doi: 10.1039/c1cc12783g. Epub 2011 Jul 1.

PMID:
21725543
50.

Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.

Anand P, Shenoy R, Palmer JE, Baines AJ, Lai RY, Robertson J, Bird N, Ostenfeld T, Chizh BA.

Eur J Pain. 2011 Nov;15(10):1040-8. doi: 10.1016/j.ejpain.2011.04.005. Epub 2011 May 14.

PMID:
21576029

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